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Search results 201 to 300 out of 644 for Hbb-b1

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Type Details Score
Publication
21536862 | J:174901
First Author: Meiler SE
Year: 2011
Journal: Blood
Title: Pomalidomide augments fetal hemoglobin production without the myelosuppressive effects of hydroxyurea in transgenic sickle cell mice.
Volume: 118
Issue: 4
Pages: 1109-12
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Publication
11520810 | J:131515
First Author: de Jong K
Year: 2001
Journal: Blood
Title: Short survival of phosphatidylserine-exposing red blood cells in murine sickle cell anemia.
Volume: 98
Issue: 5
Pages: 1577-84
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Publication
29268036 | J:274812
First Author: Potoka KP
Year: 2018
Journal: Am J Respir Cell Mol Biol
Title: Nitric Oxide-Independent Soluble Guanylate Cyclase Activation Improves Vascular Function and Cardiac Remodeling in Sickle Cell Disease.
Volume: 58
Issue: 5
Pages: 636-647
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Publication
23125209 | J:192836
First Author: Kaul DK
Year: 2013
Journal: Am J Physiol Heart Circ Physiol
Title: Antisickling fetal hemoglobin reduces hypoxia-inducible factor-1α expression in normoxic sickle mice: microvascular implications.
Volume: 304
Issue: 1
Pages: H42-50
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Publication
17158223 | J:145347
First Author: Hsu LL
Year: 2007
Journal: Blood
Title: Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability.
Volume: 109
Issue: 7
Pages: 3088-98
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Publication
26346631 | J:315127
First Author: Sopko NA
Year: 2015
Journal: J Sex Med
Title: Subacute Hemolysis in Sickle Cell Mice Causes Priapism Secondary to NO Imbalance and PDE5 Dysregulation.
Volume: 12
Issue: 9
Pages: 1878-85
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Publication
27503873 | J:235608
First Author: Bakeer N
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Sickle cell anemia mice develop a unique cardiomyopathy with restrictive physiology.
Volume: 113
Issue: 35
Pages: E5182-91
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Publication
34478834 | J:315129
 
First Author: Buehler PW
Year: 2021
Journal: Free Radic Biol Med
Title: Hemopexin dosing improves cardiopulmonary dysfunction in murine sickle cell disease.
Volume: 175
Pages: 95-107
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Publication
15073034 | J:92287
First Author: Solovey A
Year: 2004
Journal: Blood
Title: Endothelial cell expression of tissue factor in sickle mice is augmented by hypoxia/reoxygenation and inhibited by lovastatin.
Volume: 104
Issue: 3
Pages: 840-6
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Publication
16407095 | J:105707
First Author: Chang JC
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Correction of the sickle cell mutation in embryonic stem cells.
Volume: 103
Issue: 4
Pages: 1036-40
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Publication
26265698 | J:230085
First Author: Barazia A
Year: 2015
Journal: Blood
Title: Hydroxyurea with AKT2 inhibition decreases vaso-occlusive events in sickle cell disease mice.
Volume: 126
Issue: 22
Pages: 2511-7
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Publication
15489961 | J:93424
First Author: Kaul DK
Year: 2004
Journal: J Clin Invest
Title: Effect of fetal hemoglobin on microvascular regulation in sickle transgenic-knockout mice.
Volume: 114
Issue: 8
Pages: 1136-45
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Publication
30586735 | J:339793
First Author: Li J
Year: 2019
Journal: Circulation
Title: Platelet Protein Disulfide Isomerase Promotes Glycoprotein Ibα-Mediated Platelet-Neutrophil Interactions Under Thromboinflammatory Conditions.
Volume: 139
Issue: 10
Pages: 1300-1319
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Publication
26631480 | J:230900
First Author: Zhao Y
Year: 2016
Journal: FASEB J
Title: MEK1/2 inhibitors reverse acute vascular occlusion in mouse models of sickle cell disease.
Volume: 30
Issue: 3
Pages: 1171-86
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Publication
32533970 | J:300783
 
First Author: Almeida LEF
Year: 2020
Journal: Brain Res
Title: Locomotor mal-performance and gait adaptability deficits in sickle cell mice are associated with vascular and white matter abnormalities and oxidative stress in cerebellum.
Volume: 1746
Pages: 146968
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Publication
16485041 | J:106486
First Author: Belcher JD
Year: 2006
Journal: J Clin Invest
Title: Heme oxygenase-1 is a modulator of inflammation and vaso-occlusion in transgenic sickle mice.
Volume: 116
Issue: 3
Pages: 808-16
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Publication
27573019 | J:242997
First Author: Li C
Year: 2016
Journal: Mol Cell Biol
Title: Activated Transcription Factor 3 in Association with Histone Deacetylase 6 Negatively Regulates MicroRNA 199a2 Transcription by Chromatin Remodeling and Reduces Endothelin-1 Expression.
Volume: 36
Issue: 22
Pages: 2838-2854
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Publication
33045060 | J:307776
 
First Author: Xu C
Year: 2021
Journal: J Exp Med
Title: Nociceptors protect sickle cell disease mice from vaso-occlusive episodes and chronic organ damage.
Volume: 218
Issue: 1
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Publication
21483798 | J:287825
First Author: Ghosh S
Year: 2011
Journal: PLoS One
Title: Global gene expression profiling of endothelium exposed to heme reveals an organ-specific induction of cytoprotective enzymes in sickle cell disease.
Volume: 6
Issue: 3
Pages: e18399
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Publication
23913858 | J:203687
First Author: Prado GN
Year: 2013
Journal: FASEB J
Title: Endothelin-1 receptor antagonists regulate cell surface-associated protein disulfide isomerase in sickle cell disease.
Volume: 27
Issue: 11
Pages: 4619-29
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Publication
12933581 | J:134982
First Author: Levasseur DN
Year: 2003
Journal: Blood
Title: Correction of a mouse model of sickle cell disease: lentiviral/antisickling beta-globin gene transduction of unmobilized, purified hematopoietic stem cells.
Volume: 102
Issue: 13
Pages: 4312-9
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Publication
31509446 | J:281655
First Author: Gliozzi ML
Year: 2019
Journal: Am J Physiol Cell Physiol
Title: Hemoglobin alters vitamin carrier uptake and vitamin D metabolism in proximal tubule cells: implications for sickle cell disease.
Volume: 317
Issue: 5
Pages: C993-C1000
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Publication
20508165 | J:164535
First Author: Chang J
Year: 2010
Journal: Blood
Title: GMI-1070, a novel pan-selectin antagonist, reverses acute vascular occlusions in sickle cell mice.
Volume: 116
Issue: 10
Pages: 1779-86
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Publication
34039739 | J:331627
 
First Author: Sadler KE
Year: 2021
Journal: Sci Transl Med
Title: Transient receptor potential canonical 5 mediates inflammatory mechanical and spontaneous pain in mice.
Volume: 13
Issue: 595
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Publication
12972407 | J:134696
First Author: Pritchard KA Jr
Year: 2004
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Hypoxia-induced acute lung injury in murine models of sickle cell disease.
Volume: 286
Issue: 4
Pages: L705-14
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Publication
16166585 | J:129356
First Author: Manci EA
Year: 2006
Journal: Blood
Title: Pathology of Berkeley sickle cell mice: similarities and differences with human sickle cell disease.
Volume: 107
Issue: 4
Pages: 1651-8
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Publication
26852658 | J:354958
 
First Author: Choi E
Year: 2016
Journal: Blood Cells Mol Dis
Title: No evidence for cell activation or brain vaso-occlusion with plerixafor mobilization in sickle cell mice.
Volume: 57
Pages: 67-70
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Publication
26462816 | J:228649
 
First Author: Wang L
Year: 2016
Journal: Neurobiol Dis
Title: Cognitive and behavior deficits in sickle cell mice are associated with profound neuropathologic changes in hippocampus and cerebellum.
Volume: 85
Pages: 60-72
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Publication
37007990 | J:345251
 
First Author: Cendali FI
Year: 2023
Journal: Front Physiol
Title: Metabolic correlates to critical speed in murine models of sickle cell disease.
Volume: 14
Pages: 1151268
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Publication
22130804 | J:181749
First Author: Lebensburger JD
Year: 2012
Journal: Blood
Title: Hydroxyurea therapy of a murine model of sickle cell anemia inhibits the progression of pneumococcal disease by down-modulating E-selectin.
Volume: 119
Issue: 8
Pages: 1915-21
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Publication
20090940 | J:296374
First Author: Vandorpe DH
Year: 2010
Journal: PLoS One
Title: Hypoxia activates a Ca2+-permeable cation conductance sensitive to carbon monoxide and to GsMTx-4 in human and mouse sickle erythrocytes.
Volume: 5
Issue: 1
Pages: e8732
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Publication
11880644 | J:336721
First Author: Turhan A
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Primary role for adherent leukocytes in sickle cell vascular occlusion: a new paradigm.
Volume: 99
Issue: 5
Pages: 3047-51
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Publication
12064910 | J:128113
First Author: Ieremia J
Year: 2002
Journal: Blood Cells Mol Dis
Title: Limitations of a mouse model of sickle cell anemia.
Volume: 28
Issue: 2
Pages: 146-51
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Publication
30837844 | J:276862
 
First Author: Tran H
Year: 2019
Journal: Front Cell Neurosci
Title: Mast Cells Induce Blood Brain Barrier Damage in SCD by Causing Endoplasmic Reticulum Stress in the Endothelium.
Volume: 13
Pages: 56
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Publication
20926770 | J:168427
First Author: Gutsaeva DR
Year: 2011
Journal: Blood
Title: Inhibition of cell adhesion by anti-P-selectin aptamer: a new potential therapeutic agent for sickle cell disease.
Volume: 117
Issue: 2
Pages: 727-35
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Publication
24620350 | J:210886
First Author: Chen G
Year: 2014
Journal: Blood
Title: Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease.
Volume: 123
Issue: 24
Pages: 3818-27
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Publication
26023917 | J:237731
First Author: Musicki B
Year: 2015
Journal: PLoS One
Title: Mechanism of testosterone deficiency in the transgenic sickle cell mouse.
Volume: 10
Issue: 5
Pages: e0128694
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Publication
34432825 | J:354653
First Author: Brim H
Year: 2021
Journal: PLoS One
Title: The gut microbiome in sickle cell disease: Characterization and potential implications.
Volume: 16
Issue: 8
Pages: e0255956
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Publication
35793591 | J:354655
 
First Author: Woodard KJ
Year: 2022
Journal: Dis Model Mech
Title: Limitations of mouse models for sickle cell disease conferred by their human globin transgene configurations.
Volume: 15
Issue: 6
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Publication
30796025 | J:275442
First Author: Khasabova IA
Year: 2019
Journal: Blood
Title: Sensitization of nociceptors by prostaglandin E2-glycerol contributes to hyperalgesia in mice with sickle cell disease.
Volume: 133
Issue: 18
Pages: 1989-1998
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Publication
36926339 | J:345162
 
First Author: Inostroza-Nieves Y
Year: 2023
Journal: Front Immunol
Title: Blockade of endothelin-1 receptor B regulates molecules of the major histocompatibility complex in sickle cell disease.
Volume: 14
Pages: 1124269
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Publication
37482902 | J:354667
First Author: Rivera A
Year: 2023
Journal: FASEB J
Title: Blockade of the mineralocorticoid receptor improves markers of human endothelial cell dysfunction and hematological indices in a mouse model of sickle cell disease.
Volume: 37
Issue: 8
Pages: e23092
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Publication
14717789 | J:88553
First Author: Banerjee T
Year: 2004
Journal: Br J Haematol
Title: Reactive oxygen species and phosphatidylserine externalization in murine sickle red cells.
Volume: 124
Issue: 3
Pages: 391-402
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Publication
14630831 | J:88562
First Author: Turhan A
Year: 2004
Journal: Blood
Title: Intravenous immune globulin prevents venular vaso-occlusion in sickle cell mice by inhibiting leukocyte adhesion and the interactions between sickle erythrocytes and adherent leukocytes.
Volume: 103
Issue: 6
Pages: 2397-400
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Publication
20053759 | J:159262
First Author: Hebbel RP
Year: 2010
Journal: Blood
Title: The HDAC inhibitors trichostatin A and suberoylanilide hydroxamic acid exhibit multiple modalities of benefit for the vascular pathobiology of sickle transgenic mice.
Volume: 115
Issue: 12
Pages: 2483-90
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Publication
20335221 | J:162823
First Author: Sundaram N
Year: 2010
Journal: Blood
Title: High levels of placenta growth factor in sickle cell disease promote pulmonary hypertension.
Volume: 116
Issue: 1
Pages: 109-12
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Publication
20304807 | J:162824
First Author: Kohli DR
Year: 2010
Journal: Blood
Title: Pain-related behaviors and neurochemical alterations in mice expressing sickle hemoglobin: modulation by cannabinoids.
Volume: 116
Issue: 3
Pages: 456-65
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Publication
27494522 | J:256800
First Author: Lei J
Year: 2016
Journal: PLoS One
Title: Comparative Analysis of Pain Behaviours in Humanized Mouse Models of Sickle Cell Anemia.
Volume: 11
Issue: 8
Pages: e0160608
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Publication
26286849 | J:230254
First Author: Arumugam PI
Year: 2015
Journal: Blood
Title: Genetic diminution of circulating prothrombin ameliorates multiorgan pathologies in sickle cell disease mice.
Volume: 126
Issue: 15
Pages: 1844-55
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Publication
25070860 | J:354923
First Author: Kenyon N
Year: 2015
Journal: Exp Biol Med (Maywood)
Title: Sickle cell disease in mice is associated with sensitization of sensory nerve fibers.
Volume: 240
Issue: 1
Pages: 87-98
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Publication
23530053 | J:204029
First Author: Liu S
Year: 2013
Journal: Mol Cell Biol
Title: Erythropoiesis in the absence of adult hemoglobin.
Volume: 33
Issue: 11
Pages: 2241-51
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Publication
11831863 | J:128124
First Author: Noguchi CT
Year: 2001
Journal: Blood Cells Mol Dis
Title: Pathophysiology of a sickle cell trait mouse model: human alpha(beta)(S) transgenes with one mouse beta-globin allele.
Volume: 27
Issue: 6
Pages: 971-7
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Publication
25724786 | J:354927
 
First Author: Calhoun G
Year: 2015
Journal: Eur J Pharmacol
Title: Dexmedetomidine ameliorates nocifensive behavior in humanized sickle cell mice.
Volume: 754
Pages: 125-33
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Publication
35526095 | J:354926
First Author: Liu B
Year: 2022
Journal: Mol Ther
Title: Development of a double shmiR lentivirus effectively targeting both BCL11A and ZNF410 for enhanced induction of fetal hemoglobin to treat β-hemoglobinopathies.
Volume: 30
Issue: 8
Pages: 2693-2708
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Publication
37502360 | J:358481
 
First Author: Lisk C
Year: 2023
Journal: Front Med (Lausanne)
Title: Moderate hypoxia induces metabolic divergence in circulating monocytes and tissue resident macrophages from Berkeley sickle cell anemia mice.
Volume: 10
Pages: 1149005
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Publication
26124498 | J:226447
First Author: Peranteau WH
Year: 2015
Journal: Blood
Title: Correction of murine hemoglobinopathies by prenatal tolerance induction and postnatal nonmyeloablative allogeneic BM transplants.
Volume: 126
Issue: 10
Pages: 1245-54
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Publication
22033263 | J:194579
First Author: Pritchard KA Jr
Year: 2012
Journal: Am J Respir Cell Mol Biol
Title: Effects of experimental asthma on inflammation and lung mechanics in sickle cell mice.
Volume: 46
Issue: 3
Pages: 389-96
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Publication
24449213 | J:209655
First Author: Sparkenbaugh EM
Year: 2014
Journal: Blood
Title: Differential contribution of FXa and thrombin to vascular inflammation in a mouse model of sickle cell disease.
Volume: 123
Issue: 11
Pages: 1747-56
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Publication
9381190 | J:44159
First Author: Barinaga M
Year: 1997
Journal: Science
Title: Mutant mice mimic human sickle cell anemia.
Volume: 278
Issue: 5339
Pages: 803-4
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Publication
9346487 | J:44160
First Author: Ryan TM
Year: 1997
Journal: Science
Title: Knockout-transgenic mouse model of sickle cell disease.
Volume: 278
Issue: 5339
Pages: 873-6
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Publication
9346488 | J:44161
First Author: Pászty C
Year: 1997
Journal: Science
Title: Transgenic knockout mice with exclusively human sickle hemoglobin and sickle cell disease.
Volume: 278
Issue: 5339
Pages: 876-8
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Publication
38976875 | J:354027
First Author: Kim MG
Year: 2024
Journal: Blood
Title: Low-intensity transcranial focused ultrasound suppresses pain by modulating pain-processing brain circuits.
Volume: 144
Issue: 10
Pages: 1101-1115
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Publication
23844149 | J:204301
First Author: Bivalacqua TJ
Year: 2013
Journal: PLoS One
Title: Sildenafil citrate-restored eNOS and PDE5 regulation in sickle cell mouse penis prevents priapism via control of oxidative/nitrosative stress.
Volume: 8
Issue: 7
Pages: e68028
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Publication
28097236 | J:291203
First Author: Bennewitz MF
Year: 2017
Journal: JCI Insight
Title: Lung vaso-occlusion in sickle cell disease mediated by arteriolar neutrophil-platelet microemboli.
Volume: 2
Issue: 1
Pages: e89761
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Publication
20007516 | J:156179
First Author: Dasgupta T
Year: 2010
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Antisickling property of fetal hemoglobin enhances nitric oxide bioavailability and ameliorates organ oxidative stress in transgenic-knockout sickle mice.
Volume: 298
Issue: 2
Pages: R394-402
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Publication
17077320 | J:145362
First Author: Hu X
Year: 2007
Journal: Blood
Title: Transcriptional interference among the murine beta-like globin genes.
Volume: 109
Issue: 5
Pages: 2210-6
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Publication
- | J:90004
First Author: West JD
Year: 1994
Journal: Mouse Genome
Title: Transgenic Nomenclature (Correction Mouse Genome 1995;93(1):145)
Volume: 92
Issue: 4
Pages: 666-668
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3428512 | J:20298
First Author: Lo CW
Year: 1987
Journal: Differentiation
Title: Tracking of mouse cell lineage using microinjected DNA sequences: analyses using genomic Southern blotting and tissue-section in situ hybridizations.
Volume: 35
Issue: 1
Pages: 37-44
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Publication
8649401 | J:33053
First Author: Hug BA
Year: 1996
Journal: Mol Cell Biol
Title: Analysis of mice containing a targeted deletion of beta-globin locus control region 5' hypersensitive site 3.
Volume: 16
Issue: 6
Pages: 2906-12
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1709592 | J:43747
First Author: Mucenski ML
Year: 1991
Journal: Cell
Title: A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis.
Volume: 65
Issue: 4
Pages: 677-89
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Allele
Hbb<tm1Tow> | MGI:2664239
Name: hemoglobin beta chain complex; targeted mutation 1, Timothy Townes
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
7568113 | J:29087
First Author: Ciavatta DJ
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: Mouse model of human beta zero thalassemia: targeted deletion of the mouse beta maj- and beta min-globin genes in embryonic stem cells.
Volume: 92
Issue: 20
Pages: 9259-63
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Publication
31593554 | J:288590
 
First Author: Matte A
Year: 2019
Journal: JCI Insight
Title: Bitopertin, a selective oral GLYT1 inhibitor, improves anemia in a mouse model of β-thalassemia.
Volume: 4
Issue: 22
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Publication
15686467 | J:96026
First Author: Abdulmalik O
Year: 2005
Journal: Br J Haematol
Title: 5-hydroxymethyl-2-furfural modifies intracellular sickle haemoglobin and inhibits sickling of red blood cells.
Volume: 128
Issue: 4
Pages: 552-61
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Publication
31434755 | J:278703
 
First Author: Lechauve C
Year: 2019
Journal: Sci Transl Med
Title: The autophagy-activating kinase ULK1 mediates clearance of free α-globin in β-thalassemia.
Volume: 11
Issue: 506
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Publication
18579795 | J:138890
First Author: Nandedkar SD
Year: 2008
Journal: Blood
Title: Histopathology of experimentally induced asthma in a murine model of sickle cell disease.
Volume: 112
Issue: 6
Pages: 2529-38
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Publication
18318763 | J:141617
First Author: Keys JR
Year: 2008
Journal: Br J Haematol
Title: A mechanism for Ikaros regulation of human globin gene switching.
Volume: 141
Issue: 3
Pages: 398-406
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Publication
16462943 | J:115753
First Author: Yi Z
Year: 2006
Journal: PLoS Genet
Title: Sox6 directly silences epsilon globin expression in definitive erythropoiesis.
Volume: 2
Issue: 2
Pages: e14
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Publication
11566888 | J:71847
First Author: Shimizu R
Year: 2001
Journal: EMBO J
Title: In vivo requirements for GATA-1 functional domains during primitive and definitive erythropoiesis.
Volume: 20
Issue: 18
Pages: 5250-60
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Publication
15947087 | J:119377
First Author: Basu P
Year: 2005
Journal: Blood
Title: KLF2 is essential for primitive erythropoiesis and regulates the human and murine embryonic beta-like globin genes in vivo.
Volume: 106
Issue: 7
Pages: 2566-71
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Publication
23716600 | J:204573
First Author: Funnell AP
Year: 2013
Journal: Mol Cell Biol
Title: Generation of mice deficient in both KLF3/BKLF and KLF8 reveals a genetic interaction and a role for these factors in embryonic globin gene silencing.
Volume: 33
Issue: 15
Pages: 2976-87
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Publication
25870109 | J:224103
First Author: Papadopoulos P
Year: 2015
Journal: Mol Cell Biol
Title: TAF10 Interacts with the GATA1 Transcription Factor and Controls Mouse Erythropoiesis.
Volume: 35
Issue: 12
Pages: 2103-18
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Publication
11418464 | J:70187
First Author: Kaufman RM
Year: 2001
Journal: Blood
Title: Lack of neighborhood effects from a transcriptionally active phosphoglycerate kinase-neo cassette located between the murine beta-major and beta-minor globin genes.
Volume: 98
Issue: 1
Pages: 65-73
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Publication
19223557 | J:146606
First Author: Pritchard C
Year: 2009
Journal: Cancer Res
Title: Conserved gene expression programs integrate mammalian prostate development and tumorigenesis.
Volume: 69
Issue: 5
Pages: 1739-47
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Publication
19210546 | J:146843
First Author: Nagata M
Year: 2009
Journal: Genes Cells
Title: Transcription arrest relief by S-II/TFIIS during gene expression in erythroblast differentiation.
Volume: 14
Issue: 3
Pages: 371-80
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Publication
12824305 | J:117669
First Author: Battista S
Year: 2003
Journal: FASEB J
Title: Loss of Hmga1 gene function affects embryonic stem cell lympho-hematopoietic differentiation.
Volume: 17
Issue: 11
Pages: 1496-8
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Publication
20798234 | J:166627
First Author: Feng Y
Year: 2010
Journal: Blood
Title: Early mammalian erythropoiesis requires the Dot1L methyltransferase.
Volume: 116
Issue: 22
Pages: 4483-91
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Publication
19258591 | J:148521
First Author: Huo Y
Year: 2009
Journal: Blood
Title: Preclinical transfusion-dependent humanized mouse model of beta thalassemia major.
Volume: 113
Issue: 19
Pages: 4763-70
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Publication
21706023 | J:264340
First Author: Noordermeer D
Year: 2011
Journal: Nat Cell Biol
Title: Variegated gene expression caused by cell-specific long-range DNA interactions.
Volume: 13
Issue: 8
Pages: 944-51
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Publication
19235734 | J:146219
First Author: Postel EH
Year: 2009
Journal: Dev Dyn
Title: Targeted deletion of Nm23/nucleoside diphosphate kinase A and B reveals their requirement for definitive erythropoiesis in the mouse embryo.
Volume: 238
Issue: 3
Pages: 775-87
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Allele
Hbb<tm1.1(HBG1,HBB*)Ryan> | MGI:3843171
Name: hemoglobin beta chain complex; targeted mutation 1.1, Thomas M Ryan
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence, Null/knockout
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Allele
Hbb<tm2(HBG1,HBD,HBB*)Ryan> | MGI:3846101
Name: hemoglobin beta chain complex; targeted mutation 2, Thomas M Ryan
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence, Null/knockout
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
20439494 | J:162666
First Author: Miccio A
Year: 2010
Journal: Mol Cell Biol
Title: Role of the GATA-1/FOG-1/NuRD pathway in the expression of human beta-like globin genes.
Volume: 30
Issue: 14
Pages: 3460-70
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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Publication
1383089 | J:132056
First Author: Strouboulis J
Year: 1992
Journal: Genes Dev
Title: Developmental regulation of a complete 70-kb human beta-globin locus in transgenic mice.
Volume: 6
Issue: 10
Pages: 1857-64
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Publication
27707736 | J:239331
First Author: Smith EC
Year: 2016
Journal: Blood
Title: Strict in vivo specificity of the Bcl11a erythroid enhancer.
Volume: 128
Issue: 19
Pages: 2338-2342
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Publication
37042948 | J:340074
First Author: Wu J
Year: 2023
Journal: Blood Adv
Title: EHBP1L1, an apicobasal polarity regulator, is critical for nuclear polarization during enucleation of erythroblasts.
Volume: 7
Issue: 14
Pages: 3382-3394
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Publication
1954037 | J:989
First Author: Kawashima T
Year: 1991
Journal: Jpn J Genet
Title: A new haplotype of the beta-globin gene complex, Hbbw1, in Chinese wild mouse.
Volume: 66
Issue: 4
Pages: 491-500
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Genotype
Genotype
Symbol: Hbb-b1/Hbb-b1<+> Hbb-b2/Hbb-b2<+>
Background: involves: 129P2/OlaHsd * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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