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Search results 201 to 300 out of 325 for Hbp1

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:4879833
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541065
Age: embryonic day 15.5
Image: GUDMAP:5560
Specimen Label: GUDMAP:5560
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4879833
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541065
Age: embryonic day 15.5
Image: GUDMAP:5561
Specimen Label: GUDMAP:5561
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:4879833
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2874723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541065
Age: embryonic day 15.5
Image: GUDMAP:5560
Specimen Label: GUDMAP:5560
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4427871
Assay Type: RNA in situ
Annotation Date: 2011-02-15
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:4888143
Age: embryonic day 14.5
Image: Table S8
Specimen Label: Table S8
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-04-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757722
Stage: TS22
Assay Id: MGI:7464897
Age: embryonic day 14.5
Image: 5B E14.5 embryo
Specimen Label: 5B E14.5 embryo
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:4879833
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541065
Age: embryonic day 15.5
Image: GUDMAP:5560
Specimen Label: GUDMAP:5560
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:4879833
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541065
Age: embryonic day 15.5
Image: GUDMAP:5561
Specimen Label: GUDMAP:5561
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:3047302
Assay Type: RNA in situ
Annotation Date: 2004-08-12
Strength: Absent
Sex: Male
Emaps: EMAPS:1738319
Stage: TS19
Assay Id: MGI:3047323
Age: embryonic day 11.5
Image: E11.5 M
Specimen Label: E11.5 M
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3047302
Assay Type: RNA in situ
Annotation Date: 2004-08-12
Strength: Absent
Sex: Female
Emaps: EMAPS:1738319
Stage: TS19
Assay Id: MGI:3047323
Age: embryonic day 11.5
Image: E11.5 F
Specimen Label: E11.5 F
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-04-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:7464897
Age: embryonic day 14.5
Image: 5B E14.5 embryo
Specimen Label: 5B E14.5 embryo
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
Probe: MGI:3047302
Assay Type: RNA in situ
Annotation Date: 2004-08-12
Strength: Weak
Sex: Female
Emaps: EMAPS:1796221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3047323
Age: embryonic day 13.5
Image: E13.5 F
Note: Expression levels are lower in the ovary than the testis.
Specimen Label: E13.5 F
Detected: true
Specimen Num: 6
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•
GXD Expression
GXD Expression
Probe: MGI:3047302
Assay Type: RNA in situ
Annotation Date: 2004-08-12
Strength: Weak
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:3047323
Age: embryonic day 15.0
Image: E15.0 F
Note: Expression levels are lower in the ovary than the testis.
Specimen Label: E15.0 F
Detected: true
Specimen Num: 8
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•
GXD Expression
GXD Expression
Probe: MGI:3047302
Assay Type: RNA in situ
Annotation Date: 2004-08-12
Strength: Weak
Sex: Female
Emaps: EMAPS:1796224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3047323
Age: embryonic day 16.0
Image: E16.0 F
Note: Expression levels are lower in the ovary than the testis.
Specimen Label: E16.0 F
Detected: true
Specimen Num: 10
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•
GXD Expression
GXD Expression
Probe: MGI:3047302
Assay Type: RNA in situ
Annotation Date: 2004-08-12
Strength: Weak
Sex: Female
Emaps: EMAPS:1796226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:3047323
Age: embryonic day 18.0
Image: E18.0 F
Note: Expression levels are lower in the ovary than the testis.
Specimen Label: E18.0 F
Detected: true
Specimen Num: 12
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•
GXD Expression
GXD Expression
Probe: MGI:3047302
Assay Type: RNA in situ
Annotation Date: 2004-08-12
Strength: Weak
Sex: Female
Emaps: EMAPS:1796220
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3047323
Age: embryonic day 12.5
Image: E12.5 F
Note: Expression levels are lower in the ovary than the testis.
Specimen Label: E12.5 F
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
 
Probe: MGI:4879833
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541065
Age: embryonic day 15.5
Image: GUDMAP:5560
Specimen Label: GUDMAP:5560
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:7464862
Assay Type: RNA in situ
Annotation Date: 2023-04-21
Strength: Absent
Sex: Female
Emaps: EMAPS:1796222
Stage: TS22
Assay Id: MGI:7464891
Age: embryonic day 14.5
Image: 1A - XX
Specimen Label: 1A - XX
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:7464864
Assay Type: RNA in situ
Annotation Date: 2023-04-21
Strength: Present
Sex: Female
Emaps: EMAPS:1796222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7464892
Age: embryonic day 14.5
Image: 1A - XX
Specimen Label: 1A - XX
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2672022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7464897
Age: embryonic day 14.5
Image: 5B E14.5 embryo
Specimen Label: 5B E14.5 embryo
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:3585221
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3586241
Age: embryonic day 14.0
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: E14
Detected: true
Specimen Num: 2
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Publication
34358226 | J:308519
First Author: Alqurashi RS
Year: 2021
Journal: PLoS One
Title: A Warburg-like metabolic program coordinates Wnt, AMPK, and mTOR signaling pathways in epileptogenesis.
Volume: 16
Issue: 8
Pages: e0252282
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Publication
18023262 | J:130227
First Author: Millien G
Year: 2008
Journal: Gene Expr Patterns
Title: Characterization of the mid-foregut transcriptome identifies genes regulated during lung bud induction.
Volume: 8
Issue: 2
Pages: 124-39
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Publication
- | J:29505
     
First Author: Copeland NG
Year: 1999
Journal: Database Release
Title: Copeland-Jenkins (Frederick) Interspecific Backcross Mapping Data
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:82809
     
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
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Publication
15226823 | J:93300
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
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Publication
20412781 | J:140465
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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GXD Expression
GXD Expression
   
Probe: MGI:7446837
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797224
Stage: TS24
Assay Id: MGI:7464917
Age: embryonic day 16.5
Image: 6
Specimen Label: Hbp1 +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3706533
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797224
Stage: TS24
Assay Id: MGI:7464918
Age: embryonic day 16.5
Image: 6
Specimen Label: Hbp1 +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3706532
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797224
Stage: TS24
Assay Id: MGI:7464919
Age: embryonic day 16.5
Image: 6
Specimen Label: Hbp1 +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7464844
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797224
Stage: TS24
Assay Id: MGI:7464920
Age: embryonic day 16.5
Image: 6
Specimen Label: Hbp1 +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7464846
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797224
Stage: TS24
Assay Id: MGI:7464921
Age: embryonic day 16.5
Image: 6
Specimen Label: Hbp1 +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7464847
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797224
Stage: TS24
Assay Id: MGI:7464922
Age: embryonic day 16.5
Image: 6
Specimen Label: Hbp1 +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7464848
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797224
Stage: TS24
Assay Id: MGI:7464923
Age: embryonic day 16.5
Image: 6
Specimen Label: Hbp1 +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7464835
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797224
Stage: TS24
Assay Id: MGI:7464924
Age: embryonic day 16.5
Image: 6
Specimen Label: Hbp1 +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7464837
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797224
Stage: TS24
Assay Id: MGI:7464925
Age: embryonic day 16.5
Image: 6
Specimen Label: Hbp1 +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7464838
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797224
Stage: TS24
Assay Id: MGI:7464926
Age: embryonic day 16.5
Image: 6
Specimen Label: Hbp1 +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5704497
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797224
Stage: TS24
Assay Id: MGI:7464927
Age: embryonic day 16.5
Image: 6
Specimen Label: Hbp1 +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7464849
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797224
Stage: TS24
Assay Id: MGI:7464928
Age: embryonic day 16.5
Image: 6
Specimen Label: Hbp1 +/+
Detected: true
Specimen Num: 1
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•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7464841
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797224
Stage: TS24
Assay Id: MGI:7464929
Age: embryonic day 16.5
Image: 6
Specimen Label: Hbp1 +/+
Detected: true
Specimen Num: 1
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•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7464843
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797224
Stage: TS24
Assay Id: MGI:7464930
Age: embryonic day 16.5
Image: 6
Specimen Label: Hbp1 +/+
Detected: true
Specimen Num: 1
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•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7464840
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Male
Emaps: EMAPS:1797224
Stage: TS24
Assay Id: MGI:7464931
Age: embryonic day 16.5
Image: 6
Specimen Label: Hbp1 +/+
Detected: true
Specimen Num: 1
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•
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Protein
Q9D1N2
Organism: Mus musculus/domesticus
Length: 228  
Fragment?: false
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Allele
Hbp1<em1Smoc> | MGI:7290168
Name: high mobility group box transcription factor 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6354850 | C57BL/6JSmoc-Hbp1<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Publication
29911972 | -
   
First Author: Lampert F
Year: 2018
Journal: Elife
Title: The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.
Volume: 7
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•
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•
Publication
24931370 | J:213562
First Author: Yan Z
Year: 2014
Journal: FEBS Lett
Title: miR-96/HBP1/Wnt/β-catenin regulatory circuitry promotes glioma growth.
Volume: 588
Issue: 17
Pages: 3038-46
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Protein Domain
IPR036096 | Ataxin_AXH_dom_sf
Type: Homologous_superfamily
Description: Spinocerebellar ataxia type 1 is late-onset neurodegenerative diseases caused by the expansion of a CAG triplet repeat in the SCA1 gene. This results in the lengthening of a polyglutamine tract in the gene product ataxin-1 producing a toxic gain of function that results in neuronal death. The crystal structure of the AXH domain of ataxin-1 has been determined as it exhibits significant sequence similarity to the transcription factor HBP1 []and has been implicated in RNA binding and self-association. The AXH domain is dimeric and contains an OB-fold, a structural motif found in many oligonucleotide-binding proteins. By comparison to other proteins that contain an OB-fold, the putative RNA-binding region has been identified. In addition, there are a number of well-conserved residues that form a second ligand-binding surface, suggesting that AXH domains interact with a common yet unidentified partner [].
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Protein Domain
IPR003652 | Ataxin_AXH_dom
Type: Domain
Description: Spinocerebellar ataxia type 1 is late-onset neurodegenerative diseases caused by the expansion of a CAG triplet repeat in the SCA1 gene. This results in the lengthening of a polyglutamine tract in the gene product ataxin-1 producing a toxic gain of function that results in neuronal death. The crystal structure of the AXH domain of ataxin-1 has been determined as it exhibits significant sequence similarity to the transcription factor HBP1 []and has been implicated in RNA binding and self-association. The AXH domain is dimeric and contains an OB-fold, a structural motif found in many oligonucleotide-binding proteins. By comparison to other proteins that contain an OB-fold, the putative RNA-binding region has been identified. In addition, there are a number of well-conserved residues that form a second ligand-binding surface, suggesting that AXH domains interact with a common yet unidentified partner [].
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Publication
14583607 | -
First Author: Chen YW
Year: 2004
Journal: J Biol Chem
Title: The structure of the AXH domain of spinocerebellar ataxin-1.
Volume: 279
Issue: 5
Pages: 3758-65
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•
Publication
16210625 | J:119114
First Author: Sekkali B
Year: 2005
Journal: J Immunol
Title: Human high mobility group box transcription factor 1 affects thymocyte development and transgene variegation.
Volume: 175
Issue: 8
Pages: 5203-12
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•
•
•
•
Publication
28935967 | J:255564
First Author: Chen H
Year: 2017
Journal: Sci Rep
Title: MircroRNA-19a promotes vascular inflammation and foam cell formation by targeting HBP-1 in atherogenesis.
Volume: 7
Issue: 1
Pages: 12089
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•
Publication
11101889 | J:66140
First Author: Spronk CA
Year: 2000
Journal: Nat Struct Biol
Title: The Mad1-Sin3B interaction involves a novel helical fold.
Volume: 7
Issue: 12
Pages: 1100-4
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•
Protein
E9PXF9
Organism: Mus musculus/domesticus
Length: 133  
Fragment?: true
•
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•
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•
Protein
A0A1D5RM25
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: true
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•
•
•
•
Protein
Q80WX0
Organism: Mus musculus/domesticus
Length: 190  
Fragment?: true
•
•
•
•
•
Protein
Q3TN09
Organism: Mus musculus/domesticus
Length: 293  
Fragment?: false
•
•
•
•
•
Publication
14705930 | -
First Author: van Ingen H
Year: 2004
Journal: Biochemistry
Title: Extension of the binding motif of the Sin3 interacting domain of the Mad family proteins.
Volume: 43
Issue: 1
Pages: 46-54
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•
Protein
P0C7T6
Organism: Mus musculus/domesticus
Length: 687  
Fragment?: false
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Publication
18089292 | -
First Author: Sahu SC
Year: 2008
Journal: J Mol Biol
Title: Conserved themes in target recognition by the PAH1 and PAH2 domains of the Sin3 transcriptional corepressor.
Volume: 375
Issue: 5
Pages: 1444-56
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•
•
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Protein
Q9D3F4
Organism: Mus musculus/domesticus
Length: 174  
Fragment?: false
•
•
•
•
•
Protein
Q8C7X3
Organism: Mus musculus/domesticus
Length: 167  
Fragment?: true
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•
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•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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