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Search results 201 to 260 out of 260 for Hcn2

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Type Details Score
Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
30638901 | J:272918
First Author: Cheng J
Year: 2019
Journal: Neuron
Title: HCN2 Channels in Cholinergic Interneurons of Nucleus Accumbens Shell Regulate Depressive Behaviors.
Volume: 101
Issue: 4
Pages: 662-672.e5
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Publication
27621481 | J:245544
First Author: Tsantoulas C
Year: 2016
Journal: Biochem J
Title: HCN2 ion channels: basic science opens up possibilities for therapeutic intervention in neuropathic pain.
Volume: 473
Issue: 18
Pages: 2717-36
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Interaction Experiment
Ye B (2009)
Description: Proteolytic processing of HCN2 and co-assembly with HCN4 in the generation of cardiac pacemaker channels.
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GXD Expression
GXD Expression
Probe: MGI:7716808
Assay Type: Immunohistochemistry
Annotation Date: 2024-09-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284527
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7716871
Age: postnatal day 0
Image: 2A-1
Note: Expression in cells migrating from ventricular zone, more prominent for Hcn1 and Hcn2 than for Hcn4.
Specimen Label: 2A-1
Detected: true
Specimen Num: 2
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Allele
Hcn2<em1Smoc> | MGI:7290171
Name: hyperpolarization-activated, cyclic nucleotide-gated K+ 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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GO Term
GO:0098855 | HCN channel complex
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Publication
10962006 | -
First Author: Chen J
Year: 2000
Journal: J Biol Chem
Title: Functional roles of charged residues in the putative voltage sensor of the HCN2 pacemaker channel.
Volume: 275
Issue: 46
Pages: 36465-71
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Publication
21347269 | -
First Author: Hammelmann V
Year: 2011
Journal: PLoS One
Title: The cGMP-dependent protein kinase II Is an inhibitory modulator of the hyperpolarization-activated HCN2 channel.
Volume: 6
Issue: 2
Pages: e17078
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Publication
16500960 | -
First Author: Berrera M
Year: 2006
Journal: Biophys J
Title: cAMP Modulation of the cytoplasmic domain in the HCN2 channel investigated by molecular simulations.
Volume: 90
Issue: 10
Pages: 3428-33
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Strain
MGI:6770813 | C57BL/6JSmoc-Hcn2<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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GXD Expression
GXD Expression
Probe: MGI:7716808
Assay Type: Immunohistochemistry
Annotation Date: 2024-09-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3284522
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7716871
Age: embryonic day 14.5
Image: 1A,C
Note: Expression in hippocampal region, more intense in intermediate zone than in venticular zone. Expression level lower than for Hcn2 and Hcn4.
Specimen Label: 1A,C
Detected: true
Specimen Num: 1
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Allele
Tg(Hcn2-EGFP)EM66Gsat | MGI:4847122
Name: transgene insertion EM66, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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HT Experiment
GSE80378 | Identification of genes regulated by REST in developing hearts
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Hcn2<tm1Ldw> | MGI:2449917
Name: hyperpolarization-activated, cyclic nucleotide-gated K+ 2; targeted mutation 1, Andreas Ludwig
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:5003603 | STOCK Tg(Hcn2-EGFP)EM66Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Allele
Hcn2<m2Btlr> | MGI:6269370
Name: hyperpolarization-activated, cyclic nucleotide-gated K+ 2; mutation 2, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:6269371 | C57BL/6J-Hcn2<m2Btlr>
Attribute String: mutant strain, chemically induced mutation, coisogenic
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Allele
Hcn2<m3Btlr> | MGI:6285968
Name: hyperpolarization-activated, cyclic nucleotide-gated K+ 2; mutation 3, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Genotype
Genotype
Symbol: Hcn2/Hcn2
Background: C57BL/6J-Hcn2
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hcn2/Hcn2
Background: C57BL/6J-Hcn2
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hcn2/Hcn2
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Publication
10524219 | J:57463
First Author: Vaccari T
Year: 1999
Journal: Biochim Biophys Acta
Title: The human gene coding for HCN2, a pacemaker channel of the heart.
Volume: 1446
Issue: 3
Pages: 419-25
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Genotype
Genotype
Symbol: Hcn2/Hcn2 Myl7/Myl7<+>
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Publication
22006928 | J:202583
First Author: Lolicato M
Year: 2011
Journal: J Biol Chem
Title: Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.
Volume: 286
Issue: 52
Pages: 44811-20
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Publication
30079889 | J:269821
   
First Author: Qiu J
Year: 2018
Journal: Elife
Title: Estrogenic-dependent glutamatergic neurotransmission from kisspeptin neurons governs feeding circuits in females.
Volume: 7
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Publication
23382386 | J:203510
First Author: Cao-Ehlker X
Year: 2013
Journal: J Biol Chem
Title: Up-regulation of hyperpolarization-activated cyclic nucleotide-gated channel 3 (HCN3) by specific interaction with K+ channel tetramerization domain-containing protein 3 (KCTD3).
Volume: 288
Issue: 11
Pages: 7580-9
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Publication
11159823 | J:68577
First Author: Gloss B
Year: 2001
Journal: Endocrinology
Title: Cardiac ion channel expression and contractile function in mice with deletion of thyroid hormone receptor alpha or beta.
Volume: 142
Issue: 2
Pages: 544-50
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Publication
28363781 | J:244073
 
First Author: Eroli F
Year: 2017
Journal: Neuroscience
Title: Hyperpolarization-activated current Ih in mouse trigeminal sensory neurons in a transgenic mouse model of familial hemiplegic migraine type-1.
Volume: 351
Pages: 47-64
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Publication
18936078 | J:176560
First Author: Momin A
Year: 2008
Journal: J Physiol
Title: Role of the hyperpolarization-activated current Ih in somatosensory neurons.
Volume: 586
Issue: 24
Pages: 5911-29
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Publication
24368169 | J:259372
 
First Author: Phillips AM
Year: 2014
Journal: Neurobiol Dis
Title: Spike-and-wave discharge mediated reduction in hippocampal HCN1 channel function associates with learning deficits in a genetic mouse model of epilepsy.
Volume: 64
Pages: 30-5
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Publication
39584396 | J:360750
First Author: Lamia SN
Year: 2024
Journal: FASEB J
Title: Overexpression of enhanced yellow fluorescent protein fused with Channelrhodopsin-2 causes contractile dysfunction in skeletal muscle.
Volume: 38
Issue: 22
Pages: e70185
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Publication
29375299 | J:285697
 
First Author: Stieglitz MS
Year: 2017
Journal: Front Mol Neurosci
Title: Disturbed Processing of Contextual Information in HCN3 Channel Deficient Mice.
Volume: 10
Pages: 436
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Publication
29879376 | J:283930
First Author: Silbernagel N
Year: 2018
Journal: FASEB J
Title: The VAMP-associated protein VAPB is required for cardiac and neuronal pacemaker channel function.
Volume: 32
Issue: 11
Pages: 6159-6173
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Publication
22820253 | J:186776
First Author: Angelo K
Year: 2012
Journal: Nature
Title: A biophysical signature of network affiliation and sensory processing in mitral cells.
Volume: 488
Issue: 7411
Pages: 375-8
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Publication
23709563 | J:289589
First Author: Kuwabara Y
Year: 2013
Journal: J Am Heart Assoc
Title: Increased expression of HCN channels in the ventricular myocardium contributes to enhanced arrhythmicity in mouse failing hearts.
Volume: 2
Issue: 3
Pages: e000150
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Publication
20829353 | J:320085
First Author: Xu X
Year: 2010
Journal: J Biol Chem
Title: Structural basis for the cAMP-dependent gating in the human HCN4 channel.
Volume: 285
Issue: 47
Pages: 37082-91
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Publication
27670841 | J:303007
First Author: Oginsky MF
Year: 2017
Journal: J Cell Physiol
Title: Hyperexcitability of Mesencephalic Trigeminal Neurons and Reorganization of Ion Channel Expression in a Rett Syndrome Model.
Volume: 232
Issue: 5
Pages: 1151-1164
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Publication
29327340 | J:325298
First Author: Zhu M
Year: 2018
Journal: J Physiol
Title: Shank3-deficient thalamocortical neurons show HCN channelopathy and alterations in intrinsic electrical properties.
Volume: 596
Issue: 7
Pages: 1259-1276
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Publication
36745683 | J:336290
First Author: Szegedi V
Year: 2023
Journal: PLoS Biol
Title: HCN channels at the cell soma ensure the rapid electrical reactivity of fast-spiking interneurons in human neocortex.
Volume: 21
Issue: 2
Pages: e3002001
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Publication
30459593 | J:288609
 
First Author: Shen H
Year: 2018
Journal: Front Aging Neurosci
Title: Age-Dependent Up-Regulation of HCN Channels in Spiral Ganglion Neurons Coincide With Hearing Loss in Mice.
Volume: 10
Pages: 353
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Protein Coding Gene
MGI:1298211 | Hcn3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1298209 | Hcn4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1096392 | Hcn1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
- | J:100256
     
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data
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