Type |
Details |
Score |
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
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Title: |
Gene Ontology annotation based on UniPathway vocabulary mapping |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
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Title: |
Data Curation Using Mouse Genome Assembly |
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•
•
•
•
•
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Publication |
First Author: |
Visel A |
Year: |
2004 |
Journal: |
Nucleic Acids Res |
Title: |
GenePaint.org: an atlas of gene expression patterns in the mouse embryo. |
Volume: |
32 |
Issue: |
Database issue |
Pages: |
D552-6 |
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•
•
•
•
•
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Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
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•
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Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
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•
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Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
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•
•
•
•
•
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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•
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•
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Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
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•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
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•
•
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Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
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Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
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•
•
•
•
•
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Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
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•
•
•
•
•
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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•
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Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
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Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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•
•
•
•
•
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Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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•
•
•
•
•
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
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•
•
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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•
•
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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•
•
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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•
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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•
•
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•
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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•
•
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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•
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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|
GXD Expression |
Probe: |
MGI:1100579 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-06-03 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3187822 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7643980 |
Age: |
embryonic day 14.5 |
|
Note: |
Restricted to the labyrinth zone, opposite that of Hsd17b7 and Prl6a1. |
Specimen Label: |
3G |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Breitling R |
Year: |
2001 |
Journal: |
Mol Cell Endocrinol |
Title: |
17beta-hydroxysteroid dehydrogenase type 7--an ancient 3-ketosteroid reductase of cholesterogenesis. |
Volume: |
171 |
Issue: |
1-2 |
Pages: |
199-204 |
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•
•
•
•
•
|
Publication |
First Author: |
Krazeisen A |
Year: |
1999 |
Journal: |
FEBS Lett |
Title: |
Determination of cDNA, gene structure and chromosomal localization of the novel human 17beta-hydroxysteroid dehydrogenase type 7(1). |
Volume: |
460 |
Issue: |
2 |
Pages: |
373-9 |
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•
•
•
•
•
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Publication |
First Author: |
Pierson CA |
Year: |
2004 |
Journal: |
Med Mycol |
Title: |
Isolation, characterization, and regulation of the Candida albicans ERG27 gene encoding the sterol 3-keto reductase. |
Volume: |
42 |
Issue: |
5 |
Pages: |
461-73 |
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•
•
•
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Protein Domain |
Type: |
Family |
Description: |
This entry includes a group of 3-keto-steroid reductases, including 17beta-HSD7 (or HSD17B7) from animals and Erg27 from fungi. 3-keto steroid reductase (in concert with other enzymes) catalyzes NADP-dependent sterol C-4 demethylation, as part of steroid biosynthesis. 3-keto reductase is a classical short-chain dehydrogenase/reductase (SDR), with a well conserved canonical active site tetrad and fairly well conserved characteristic NAD-binding motif [, ]. HSD17B7 is the orthologue of the yeast steroid-3-ketoreductase (Erg27), an enzyme of ergosterol biosynthesis []. HSD17B7 catalyses the conversion of estrone (a 17beta-hydroxysteroid) to the biologically active estradiol [, , ]. Similar to Erg27, it also acts as a 3-ketosteroid reductase [].In humans, predominant expression of 17beta-HSD7 is found not only in reproductive tissues (breast, ovary, placenta) but also in liver and developing brain, principal sites of cholesterol synthesis in keeping with the bifunctional nature of this enzyme [, ]. |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
334
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
362
 |
Fragment?: |
false |
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•
•
•
•
•
|
Publication |
First Author: |
Tu X |
Year: |
2018 |
Journal: |
Reprod Biol Endocrinol |
Title: |
The ovarian estrogen synthesis function was impaired in Y123F mouse and partly restored by exogenous FSH supplement. |
Volume: |
16 |
Issue: |
1 |
Pages: |
44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Le JA |
Year: |
2012 |
Journal: |
Biol Reprod |
Title: |
Generation of mice expressing only the long form of the prolactin receptor reveals that both isoforms of the receptor are required for normal ovarian function. |
Volume: |
86 |
Issue: |
3 |
Pages: |
86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Persson B |
Year: |
2003 |
Journal: |
Chem Biol Interact |
Title: |
Coenzyme-based functional assignments of short-chain dehydrogenases/reductases (SDRs). |
Volume: |
143-144 |
|
Pages: |
271-8 |
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•
•
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•
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