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Search results 201 to 300 out of 313 for Ing4

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:4417488
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825591
Age: embryonic day 14.5
Image: euxassay_011920_11
Specimen Label: euxassay_011920_11
Detected: true
Specimen Num: 11
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417488
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825591
Age: embryonic day 14.5
Image: euxassay_011920_12
Specimen Label: euxassay_011920_12
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417488
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825591
Age: embryonic day 14.5
Image: euxassay_011920_13
Specimen Label: euxassay_011920_13
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417488
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825591
Age: embryonic day 14.5
Image: euxassay_011920_14
Specimen Label: euxassay_011920_14
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417488
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825591
Age: embryonic day 14.5
Image: euxassay_011920_15
Specimen Label: euxassay_011920_15
Detected: true
Specimen Num: 15
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417488
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825591
Age: embryonic day 14.5
Image: euxassay_011920_16
Specimen Label: euxassay_011920_16
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417488
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825591
Age: embryonic day 14.5
Image: euxassay_011920_17
Specimen Label: euxassay_011920_17
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417488
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825591
Age: embryonic day 14.5
Image: euxassay_011920_18
Specimen Label: euxassay_011920_18
Detected: true
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417488
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825591
Age: embryonic day 14.5
Image: euxassay_011920_19
Specimen Label: euxassay_011920_19
Detected: true
Specimen Num: 19
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507271
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3267921
Stage: TS21
Assay Id: MGI:3508243
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507271
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3267927
Stage: TS27
Assay Id: MGI:3508243
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3507271
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540191
Age: embryonic day 15.5
Image: GUDMAP:6152
Specimen Label: GUDMAP:6152
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507271
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757721
Stage: TS21
Assay Id: MGI:3508243
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507271
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:3508243
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417488
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1784723
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825591
Age: embryonic day 14.5
Image: euxassay_011920_08
Specimen Label: euxassay_011920_08
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417488
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1784723
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825591
Age: embryonic day 14.5
Image: euxassay_011920_09
Specimen Label: euxassay_011920_09
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417488
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1784723
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825591
Age: embryonic day 14.5
Image: euxassay_011920_10
Specimen Label: euxassay_011920_10
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417488
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1784723
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825591
Age: embryonic day 14.5
Image: euxassay_011920_11
Specimen Label: euxassay_011920_11
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417488
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1872223
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825591
Age: embryonic day 14.5
Image: euxassay_011920_02
Specimen Label: euxassay_011920_02
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417488
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1872223
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825591
Age: embryonic day 14.5
Image: euxassay_011920_03
Specimen Label: euxassay_011920_03
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417488
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1872223
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825591
Age: embryonic day 14.5
Image: euxassay_011920_16
Specimen Label: euxassay_011920_16
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417488
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1872223
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825591
Age: embryonic day 14.5
Image: euxassay_011920_17
Specimen Label: euxassay_011920_17
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3507271
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540191
Age: embryonic day 15.5
Image: GUDMAP:6152
Specimen Label: GUDMAP:6152
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3526314
Assay Type: RNA in situ
Annotation Date: 2005-02-14
Strength: Present
Sex: Female
Emaps: EMAPS:1796221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3526372
Age: embryonic day 12.5
Specimen Label: not shown
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417488
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1870623
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825591
Age: embryonic day 14.5
Image: euxassay_011920_08
Specimen Label: euxassay_011920_08
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417488
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1870623
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825591
Age: embryonic day 14.5
Image: euxassay_011920_09
Specimen Label: euxassay_011920_09
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417488
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1870623
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825591
Age: embryonic day 14.5
Image: euxassay_011920_10
Specimen Label: euxassay_011920_10
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417488
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1870623
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825591
Age: embryonic day 14.5
Image: euxassay_011920_11
Specimen Label: euxassay_011920_11
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417488
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1870623
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825591
Age: embryonic day 14.5
Image: euxassay_011920_12
Specimen Label: euxassay_011920_12
Detected: true
Specimen Num: 12
•
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•
•
•
Publication
7482790 | J:31523
First Author: Bassett DE Jr
Year: 1995
Journal: Trends Genet
Title: Comparative genomics, genome cross-referencing and XREFdb.
Volume: 11
Issue: 9
Pages: 372-3
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Publication
11888890 | J:76889
First Author: Ha S
Year: 2002
Journal: Cancer Res
Title: Mouse ING1 homologue, a protein interacting with A1, enhances cell death and is inhibited by A1 in mammary epithelial cells.
Volume: 62
Issue: 5
Pages: 1275-8
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Publication
- | J:94077
     
First Author: Mutant Mouse Regional Resource Centers
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC)
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Publication
20211142 | J:160776
First Author: Ravasi T
Year: 2010
Journal: Cell
Title: An atlas of combinatorial transcriptional regulation in mouse and man.
Volume: 140
Issue: 5
Pages: 744-52
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Publication
14595844 | J:86589
First Author: McClive PJ
Year: 2003
Journal: Genesis
Title: Subtractive hybridisation screen identifies sexually dimorphic gene expression in the embryonic mouse gonad.
Volume: 37
Issue: 2
Pages: 84-90
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Publication
- | J:200814
     
First Author: Toronto Centre for Phenogenomics
Year: 2013
Journal: MGI Direct Data Submission
Title: Strains and alleles submitted by Toronto Centre for Phenogenomics (NorCOMM2, funded by Genome Canada and Ontario Genomics Institute OGI-051).
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Publication
9811942 | J:50869
First Author: Ko MS
Year: 1998
Journal: Hum Mol Genet
Title: Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome.
Volume: 7
Issue: 12
Pages: 1967-78
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Publication
19521500 | J:149737
First Author: Sansom SN
Year: 2009
Journal: PLoS Genet
Title: The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.
Volume: 5
Issue: 6
Pages: e1000511
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:24194
     
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
22988430 | J:190636
 
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
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Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
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•
•
•
Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
20412781 | J:140465
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
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First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
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First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
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First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
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First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q6P8Q6
Organism: Mus musculus/domesticus
Length: 167  
Fragment?: false
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Interaction Experiment
Raho G (2007)
Description: Detection of novel mRNA splice variants of human ING4 tumor suppressor gene.
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Publication
15251430 | -
First Author: Zhang X
Year: 2004
Journal: FEBS Lett
Title: ING4 induces G2/M cell cycle arrest and enhances the chemosensitivity to DNA-damage agents in HepG2 cells.
Volume: 570
Issue: 1-3
Pages: 7-12
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Publication
17325660 | -
First Author: Raho G
Year: 2007
Journal: Oncogene
Title: Detection of novel mRNA splice variants of human ING4 tumor suppressor gene.
Volume: 26
Issue: 36
Pages: 5247-57
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Publication
15528276 | -
First Author: Kim S
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: A screen for genes that suppress loss of contact inhibition: identification of ING4 as a candidate tumor suppressor gene in human cancer.
Volume: 101
Issue: 46
Pages: 16251-6
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Allele
Ing4<Gt(XG370)Byg> | MGI:3587932
Name: inhibitor of growth family, member 4; gene trap XG370, BayGenomics
Allele Type: Gene trapped
Attribute String: Null/knockout, Reporter
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Strain
MGI:4357875 | B6;129P2-Ing4<Gt(XG370)Byg>/Mmucd
Attribute String: gene trap, mutant stock
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Genotype
Genotype
Symbol: Ing4/Ing4
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Publication
16387653 | J:320046
First Author: Doyon Y
Year: 2006
Journal: Mol Cell
Title: ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.
Volume: 21
Issue: 1
Pages: 51-64
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HT Experiment
GSE246403 | RNA sequencing data of Ing4;Ing5 compound mutant embryonic mouse hearts (ING4 and ING5 are essential for histone H3 lysine 14 acetylation and epicardial cell lineage development)
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE246402 | RNA sequencing data of Kat6a (Moz) mutant embryonic mouse hearts (ING4 and ING5 are essential for histone H3 lysine 14 acetylation and epicardial cell lineage development)
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE252338 | RNA sequencing data of Ing4;Ing5 double knock-out embryonic mouse hearts
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Protein Domain
IPR039549 | JADE2_ePHD
Type: Domain
Description: The ePHD ("extended plant homeodomain") zinc finger is characterized as Cys2HisCys5HisCys2His. This entry represents the ePHD finger of Jade-2. Jade-2 is a homeodomain (PHD) zinc finger protein that is closely related to Jade-1, which functions as an essential regulator of multiple cell signaling pathways. Like Jade-1, Jade-2 is required for ING4 and ING5 to associate with histone acetyltransferase (HAT) HBO1 and Eaf6 to form a HBO1 complex that has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3, and is responsible for the bulk of histone H4 acetylation in vivo. Jade-2 contains a canonical PHD finger followed by this non-canonical ePHD finger, both of which are zinc-binding motifs [, ].
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Protein Domain
IPR042009 | BRPF2_PHD
Type: Domain
Description: This entry represents the PHD finger of BRPF2 (also known as BRD1) [].BRPF2 is responsible for the bulk of the acetylation of H3K14 and forms a novel monocytic leukemic zinc-finger protein (MOZ)/MOZ-related factor (MORF) H3 histone acetyltransferase (HAT) complex with HBO1 and ING4 []. The complex is required for full transcriptional activation of the erythroid-specific regulator genes essential for terminal differentiation and survival of erythroblasts in fetal liver []. It contains a cysteine rich region harbouring a plant homeodomain (PHD) finger followed by a non-canonical ePHD finger, a bromodomain, and a proline-tryptophan-tryptophan-proline (PWWP) domain.
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Protein Domain
IPR039548 | JADE2_PHD
Type: Domain
Description: Jade-2, also termed PHD finger protein 15 (PHF15), is a PHD ("plant homeodomain") zinc finger protein that is closely related to Jade-1, which functions as an essential regulator of multiple cell signaling pathways. Like Jade-1, Jade-2 is required for ING4 and ING5 to associate with histone acetyltransferase (HAT) HBO1 and Eaf6 to form a HBO1 complex that has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3, and is responsible for the bulk of histone H4 acetylation in vivo. Jade-2 contains a canonical Cys4HisCys3 PHD finger followed by a non-canonical extended PHD (ePHD) finger, Cys2HisCys5HisCys2His, both of which are zinc-binding motifs. This entry represents the canonical Cys4HisCys3 PHD finger [, ].
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Publication
21753189 | J:177092
First Author: Mishima Y
Year: 2011
Journal: Blood
Title: The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation of H3K14 and required for fetal liver erythropoiesis.
Volume: 118
Issue: 9
Pages: 2443-53
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Publication
14612400 | J:86562
First Author: Tzouanacou E
Year: 2003
Journal: Mol Cell Biol
Title: Identification of Jade1, a gene encoding a PHD zinc finger protein, in a gene trap mutagenesis screen for genes involved in anteroposterior axis development.
Volume: 23
Issue: 23
Pages: 8553-2
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Publication
10775800 | -
First Author: Szelei J
Year: 2000
Journal: J Steroid Biochem Mol Biol
Title: Identification of human estrogen-inducible transcripts that potentially mediate the apoptotic response in breast cancer.
Volume: 72
Issue: 3-4
Pages: 89-102
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Protein Domain
IPR042004 | BRPF2_ePHD
Type: Domain
Description: This entry represents the ePHD finger of bromodomain and PHD finger-containing protein 2 (BRPF2), also known as bromodomain-containing protein 1 (BRD1). The extended plant homeodomain (ePHD) zinc finger is characterized as Cys2HisCys5HisCys2His. BRPF2 is responsible for the bulk of the acetylation of H3K14 and forms a novel monocytic leukemic zinc-finger protein (MOZ)/MOZ-related factor (MORF) H3 histone acetyltransferase (HAT) complex with HBO1 and ING4 []. The complex is required for full transcriptional activation of the erythroid-specific regulator genes essential for terminal differentiation and survival of erythroblasts in fetal liver []. It contains a cysteine rich region harbouring a plant homeodomain (PHD) finger followed by a non-canonical ePHD finger, a bromodomain, and a proline-tryptophan-tryptophan-proline (PWWP) domain.
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Protein Domain
IPR039550 | JADE3_PHD
Type: Domain
Description: Jade-3, also termed PHD finger protein 16 (PHF16), is a PHD ("plant homeodomain") zinc finger protein that is closely related to Jade-1, which functions as an essential regulator of multiple cell signaling pathways. Like Jade-1, Jade-3 is required for ING4 and ING5 to associate with histone acetyl transferase (HAT) HBO1 and Eaf6 to form a HBO1 complex that has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3, and is responsible for the bulk of histone H4 acetylation in vivo. Jade-3 contains a canonical Cys4HisCys3 PHD domain followed by a non-canonical extended PHD (ePHD) domain, Cys2HisCys5HisCys2His, both of which are zinc-binding motifs. This model corresponds to the canonical Cys4HisCys3 PHD finger [, ].
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Publication
12169691 | -
First Author: Zhou MI
Year: 2002
Journal: J Biol Chem
Title: The von Hippel-Lindau tumor suppressor stabilizes novel plant homeodomain protein Jade-1.
Volume: 277
Issue: 42
Pages: 39887-98
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Publication
23824745 | -
First Author: Zeng L
Year: 2013
Journal: Cancer Res
Title: Candidate tumor suppressor and pVHL partner Jade-1 binds and inhibits AKT in renal cell carcinoma.
Volume: 73
Issue: 17
Pages: 5371-80
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Publication
16046545 | -
First Author: Zhou MI
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Jade-1, a candidate renal tumor suppressor that promotes apoptosis.
Volume: 102
Issue: 31
Pages: 11035-40
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Publication
1880678 | -
First Author: Hunter PR
Year: 1991
Journal: J Med Vet Mycol
Title: The sub-specific numerical analysis of Candida albicans.
Volume: 29
Issue: 2
Pages: 105-15
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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