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Search results 201 to 300 out of 2110 for Ino80

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Hits by Strain

Type Details Score
Gene
709107 | INO80B
Type: gene
Organism: macaque, rhesus
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Gene
100493655 | ino80d
Type: gene
Organism: frog, western clawed
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Gene
101731482 | ino80c
Type: gene
Organism: frog, western clawed
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Gene
100169675 | ino80e
Type: gene
Organism: frog, western clawed
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Gene
100216277 | ino80b
Type: gene
Organism: frog, western clawed
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Gene
107049493 | INO80B
Type: gene
Organism: chicken
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Gene
110440037 | ino80da
Type: gene
Organism: zebrafish
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Gene
121112804 | LOC121112804
Type: gene
Organism: chicken
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Protein Domain
IPR029523 | INO80B/Ies2
Type: Family
Description: This entry represents INO80 complex subunit 2 (Ies2), also known as INO80 complex subunit B (INO80B). INO80 is involved in transcriptional regulation, DNA replication and probably DNA repair []. Ies2 functions as a molecular switch that potently activates INO80 DNA-dependent ATPase activity [].
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Publication
10952318 | -
First Author: Shen X
Year: 2000
Journal: Nature
Title: A chromatin remodelling complex involved in transcription and DNA processing.
Volume: 406
Issue: 6795
Pages: 541-4
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Protein Domain
IPR038014 | Ies1
Type: Family
Description: Ino80 subunit 1 (Ies1) is a component of the INO80 chromatin remodelling complex [].The INO80 complex is involved in transcriptional regulation, DNA replication and probably DNA repair. It remodels chromatin by increasing nucleosome mobility thus allowing access to enzymes that process DNA. Hydrolysis of ATP is required and the INO80 component is an ATPase []. The complex in yeast is composed of at least ARP4, ARP5, ARP8, RVB1, RVB2, TAF14, NHP10, IES1, IES3, IES4, IES6, ACT1, IES2, IES5 and INO80 [, ].
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Protein
Q7TMJ7
Organism: Mus musculus/domesticus
Length: 138  
Fragment?: false
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Protein Domain
IPR026678 | INO80E
Type: Family
Description: Proteins in this family are INO80 complex subunit E, a metazoan-specific subunit []. Subunit E is a putative regulatory component of the chromatin remodeling INO80 complex, which is involved in transcriptional regulation, DNA replication and probably DNA repair [].
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Protein Domain
IPR032742 | Iec3
Type: Family
Description: INO80 complex subunit 3 (Iec3) is a component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair []. Interestingly, there is no Iec3 orthologue found in S. cerevisiae.
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ncRNA Gene
MGI:3651861 | Ino80dos
Type: lncRNA_gene
Organism: mouse, laboratory
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UniProt Feature
UniProt Feature
Begin: 1
Description: Chromatin-remodeling ATPase INO80
Type: chain
End: 1559
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UniProt Feature
UniProt Feature
Begin: 1
Description: INO80 complex subunit B
Type: chain
End: 375
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UniProt Feature
UniProt Feature
Begin: 1
Description: INO80 complex subunit D
Type: chain
End: 1021
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UniProt Feature
UniProt Feature
Begin: 1
Description: INO80 complex subunit C
Type: chain
End: 191
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Allele
Ino80<em1Smoc> | MGI:7290549
Name: INO80 complex subunit; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
31418686 | -
   
First Author: Zander M
Year: 2019
Journal: Elife
Title: Epigenetic silencing of a multifunctional plant stress regulator.
Volume: 8
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Protein Domain
IPR029525 | INO80C/Ies6
Type: Family
Description: This entry represents INO80 complex subunit Ies6 (also known as INO80 complex subunit C, INO80C). INO80 is involved in transcriptional regulation, DNA replication and probably DNA repair []. Together with Arp5, Ies6 promotes binding of the INO80 complex to nucleosomes to help initiate the remodeling reaction []. The homologue from Arabidopsis ENN mediates a regulatory mechanism that monitors the expression of the essential multifunctional plant stress regulator EIN2 via H3K27me3 repressive histone demethylation and histone variant H2A.Z eviction, thus modulating responses to ethylene (ET), especially during embryogenesis [].
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Publication
24297934 | -
First Author: Chen L
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Multiple modes of regulation of the human Ino80 SNF2 ATPase by subunits of the INO80 chromatin-remodeling complex.
Volume: 110
Issue: 51
Pages: 20497-502
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Protein Domain
IPR013175 | INO80_su_Ies4
Type: Family
Description: The INO80 ATPase is a member of the SNF2 family of ATPases and functions as an integral component of a multisubunit ATP-dependent chromatin remodelling complex. This family of proteins corresponds to the fungal Ies4 subunit of INO80.
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Protein Domain
IPR020366 | Ies5
Type: Family
Description: The INO80 complex is involved in chromatin-remodelling by promoting the repositioning (sliding) or eviction of nucleosomes from the DNA in an ATP-dependent process. The INO80 chromatin-remodelling complex of Saccharomyces cerevisiae (Baker's yeast) is composed of at least 15 subunits and has a molecular mass of about 1.2 to 1.5 MDa. In S. cerevisiae the core conserved subunits are: ATPase; Ino80.RuvB-like; Rvb1 and Rvb2.Actin; Act1.Actin-related: Arp4, Arp5 and Arp8.YEATS protein []; Taf14.The non-conserved subunits are: Ies1, Ies2, Ies3, Ies4, Ies5, Ies6 and Nhp10 []. The Ino80 ATPase is a member of the SNF2 family of ATPases and functions as an integral component of a multisubunit ATP-dependent chromatin remodelling complex that is conserved from yeast to mammals. Although INO80 complexes from yeast and higher eukaryotes share a common core of conserved subunits, the complexes have diverged substantially during evolution and have acquired new subunits with apparently species-specific functions. Studies in S. cerevisiae have shown that the conserved HSA (helicase) domain of the ATPase subunit, Ino80, is required for the binding of the Arp's and Act1, and this conserved module links the chromatin-remodelling complex to itssubstrate, the nucleosome [, ]. In eukaryotes the chromatin-remodelling complexes such as the SWR1 and INO80 complexes have many crucial functions including the control of gene regulation and expression, checkpoint regulation, DNA replication and repair, telomer maintenance and chromosomal segregation and as such represent critical components of pathways that maintain genomic integrity [, , ].This entry represents the INO80 subunit 5 or Ies5, which has been shown to associate with the INO80 chromatin-remodelling complex under low-salt conditions [], though its function is unknown.
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Gene
100426936 | LOC100426936
Type: gene
Organism: macaque, rhesus
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Gene
114673729 | LOC114673729
Type: gene
Organism: macaque, rhesus
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HT Experiment
GSE133799 | Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80 [RNA-seq]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
20971067 | -
First Author: Kashiwaba S
Year: 2010
Journal: Biochem Biophys Res Commun
Title: The mammalian INO80 complex is recruited to DNA damage sites in an ARP8 dependent manner.
Volume: 402
Issue: 4
Pages: 619-25
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Strain
MGI:6770861 | C57BL/6JSmoc-Ino80<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Protein Domain
IPR006880 | INO80B_C
Type: Domain
Description: This is a group of proteins with a conserved C-terminal region which is found in INO80 complex subunit B (INO80B, Ies2 homologue, also known as PAPA-1). INO80B is a component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair [, ].
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Publication
12887900 | -
First Author: Shen X
Year: 2003
Journal: Mol Cell
Title: Involvement of actin-related proteins in ATP-dependent chromatin remodeling.
Volume: 12
Issue: 1
Pages: 147-55
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Protein
Q66JY2
Organism: Mus musculus/domesticus
Length: 1021  
Fragment?: false
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Protein
Q66JY2-4
Organism: Mus musculus/domesticus
Length: 916  
Fragment?: false
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Protein
D6RES5
Organism: Mus musculus/domesticus
Length: 25  
Fragment?: false
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Protein
B1AT34
Organism: Mus musculus/domesticus
Length: 434  
Fragment?: true
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Protein
A0A0U1RPF6
Organism: Mus musculus/domesticus
Length: 81  
Fragment?: true
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Protein
A0A0U1RNZ5
Organism: Mus musculus/domesticus
Length: 36  
Fragment?: true
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Protein
B1AT33
Organism: Mus musculus/domesticus
Length: 438  
Fragment?: true
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Protein
B1AT32
Organism: Mus musculus/domesticus
Length: 916  
Fragment?: false
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Protein
D3YV78
Organism: Mus musculus/domesticus
Length: 60  
Fragment?: true
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Gene
100101296 | ino80b.S
Type: gene
Organism: frog, African clawed
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Gene
108699272 | ino80.L
Type: gene
Organism: frog, African clawed
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Gene
108703062 | ino80d.S
Type: gene
Organism: frog, African clawed
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Gene
108703783 | ino80e.L
Type: gene
Organism: frog, African clawed
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Gene
108704288 | ino80e.S
Type: gene
Organism: frog, African clawed
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Gene
108704444 | ino80.S
Type: gene
Organism: frog, African clawed
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Gene
108704917 | ino80c.S
Type: gene
Organism: frog, African clawed
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Gene
735080 | ino80d.L
Type: gene
Organism: frog, African clawed
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Publication
19040720 | -
First Author: Shevchenko A
Year: 2008
Journal: Genome Biol
Title: Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment.
Volume: 9
Issue: 11
Pages: R167
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Protein Coding Gene
MGP_CAROLIEiJ_G0014196 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_CAROLIEiJ_G0022047 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_CAROLIEiJ_G0030470 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0016084 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_129S1SvImJ_G0024198 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_129S1SvImJ_G0033004 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0016067 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0024163 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032987 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0016024 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0024132 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0032919 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0016022 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0024163 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0032992 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0015854 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0023931 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0032702 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_3027003 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2443014 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2141881 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0016475 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0024605 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0033498 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0015437 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0023405 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0032031 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0015826 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0023899 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0032675 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0015927 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0024031 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0032827 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0015930 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0023997 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0032780 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0015999 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0024112 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0032921 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0015950 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0024025 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0032812 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0016522 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0024653 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0033517 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0015224 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0023149 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0031738 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0015499 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0023469 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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