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Search results 201 to 238 out of 238 for Insl3

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0.022s
Type Details Score
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication  
First Author: Ferlin A
Year: 2018
Journal: Front Endocrinol (Lausanne)
Title: Protective Role of Testicular Hormone INSL3 From Atrophy and Weakness in Skeletal Muscle.
Volume: 9
Pages: 562
Allele
Name: insulin-like 3; targeted mutation 1, Luis F Parada
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: transgene insertion 4, Ibrahim M Adham
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Publication
First Author: Esteban-Lopez M
Year: 2022
Journal: Commun Biol
Title: Discovery of small molecule agonists of the Relaxin Family Peptide Receptor 2.
Volume: 5
Issue: 1
Pages: 1183
Genotype
Symbol: Insl3/Insl3
Background: involves: 129/Sv * CD-1
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Insl3/Insl3<+>
Background: involves: 129/Sv * CD-1
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Tg(Ins2-Insl3)4Imad/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Brogiolo W
Year: 2001
Journal: Curr Biol
Title: An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control.
Volume: 11
Issue: 4
Pages: 213-21
Protein Domain
Type: Family
Description: This entry includes insulin-like 3 from mammals and probable insulin-like peptide 4 (Ilp4 or dILP4) from fruit flies [].Insulin-like 3 (INSL3) is a secreted protein produced by testicular Leydig cells and in lower amounts by ovarian follicular theca interna cells and the corpus luteum []. It acts as a theca cell-derived growth factor for preantral follicle and its action is mediated by growth differentiation factor 9 []. Signaling through INSL3 and its cognate G protein-coupled receptor RXFP2 is important for testicular descent. It seems to be dispensable for spermatogenesis and fertility in adult males [].The function of Ilp4 is not clear.
Genotype
Symbol: Rxfp1/Rxfp1 Tg(Ins2-Insl3)4Imad/?
Background: involves: 129S7/SvEvBrd * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Nef S
Year: 2000
Journal: Dev Biol
Title: A molecular basis for estrogen-induced cryptorchidism.
Volume: 224
Issue: 2
Pages: 354-61
Publication
First Author: Li Z
Year: 2011
Journal: Endocrinology
Title: Uterine cysts in female mice deficient for caveolin-1 and insulin-like 3 receptor RXFP2.
Volume: 152
Issue: 6
Pages: 2474-82
Publication
First Author: Feng S
Year: 2007
Journal: Biol Reprod
Title: Developmental expression and gene regulation of insulin-like 3 receptor RXFP2 in mouse male reproductive organs.
Volume: 77
Issue: 4
Pages: 671-80
Publication
First Author: Yuan FP
Year: 2006
Journal: Hum Reprod
Title: Cryptorchidism in LhrKO animals and the effect of testosterone-replacement therapy.
Volume: 21
Issue: 4
Pages: 936-42
Publication
First Author: Yuan FP
Year: 2010
Journal: Reproduction
Title: The role of RXFP2 in mediating androgen-induced inguinoscrotal testis descent in LH receptor knockout mice.
Volume: 139
Issue: 4
Pages: 759-69
Publication
First Author: Shirneshan K
Year: 2008
Journal: Mol Cell Endocrinol
Title: Directed overexpression of insulin in Leydig cells causes a progressive loss of germ cells.
Volume: 295
Issue: 1-2
Pages: 79-86
Publication
First Author: Cederroth CR
Year: 2007
Journal: Endocrinology
Title: Estrogen receptor alpha is a major contributor to estrogen-mediated fetal testis dysgenesis and cryptorchidism.
Volume: 148
Issue: 11
Pages: 5507-19
Publication
First Author: Bathgate RA
Year: 2006
Journal: Biochemistry
Title: Relaxin-3: improved synthesis strategy and demonstration of its high-affinity interaction with the relaxin receptor LGR7 both in vitro and in vivo.
Volume: 45
Issue: 3
Pages: 1043-53
Publication
First Author: Ferlin A
Year: 2008
Journal: J Bone Miner Res
Title: Mutations in the insulin-like factor 3 receptor are associated with osteoporosis.
Volume: 23
Issue: 5
Pages: 683-93