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Search results 201 to 293 out of 293 for Irf5

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Type Details Score
Publication
20456021 | J:162497
First Author: Okun E
Year: 2010
Journal: J Neurochem
Title: TLR2 activation inhibits embryonic neural progenitor cell proliferation.
Volume: 114
Issue: 2
Pages: 462-74
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Publication
10788617 | J:61896
First Author: Lee YJ
Year: 2000
Journal: FEBS Lett
Title: Mit1/Lb9 and Copg2, new members of mouse imprinted genes closely linked to Peg1/Mest(1).
Volume: 472
Issue: 2-3
Pages: 230-4
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Publication
33357409 | J:303987
First Author: Yousif AS
Year: 2021
Journal: Immunity
Title: The persistence of interleukin-6 is regulated by a blood buffer system derived from dendritic cells.
Volume: 54
Issue: 2
Pages: 235-246.e5
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Publication
37021574 | J:360893
First Author: Faragher JL
Year: 2023
Journal: Arterioscler Thromb Vasc Biol
Title: Autoimmune Valvular Carditis Requires Endothelial Cell TNFR1 Expression.
Volume: 43
Issue: 6
Pages: 943-957
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Publication
32123346 | J:360216
First Author: Burke TP
Year: 2020
Journal: Nat Microbiol
Title: Inflammasome-mediated antagonism of type I interferon enhances Rickettsia pathogenesis.
Volume: 5
Issue: 5
Pages: 688-696
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Publication
28468974 | J:247750
First Author: Zhu Q
Year: 2017
Journal: J Immunol
Title: Cutting Edge: Distinct Regulatory Mechanisms Control Proinflammatory Cytokines IL-18 and IL-1β.
Volume: 198
Issue: 11
Pages: 4210-4215
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Publication
19652017 | J:152182
First Author: McWhirter SM
Year: 2009
Journal: J Exp Med
Title: A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP.
Volume: 206
Issue: 9
Pages: 1899-911
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Publication
34249474 | J:353174
First Author: Shah D
Year: 2021
Journal: Oncoimmunology
Title: A novel miR1983-TLR7-IFNβ circuit licenses NK cells to kill glioma cells, and is under the control of galectin-1.
Volume: 10
Issue: 1
Pages: 1939601
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Publication
21820332 | J:175845
First Author: Sharma S
Year: 2011
Journal: Immunity
Title: Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome.
Volume: 35
Issue: 2
Pages: 194-207
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Publication
26358260 | J:239050
First Author: Sager HB
Year: 2015
Journal: Circulation
Title: Targeting Interleukin-1β Reduces Leukocyte Production After Acute Myocardial Infarction.
Volume: 132
Issue: 20
Pages: 1880-90
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Publication
33278357 | J:361144
First Author: Karki R
Year: 2021
Journal: Cell
Title: Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes.
Volume: 184
Issue: 1
Pages: 149-168.e17
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Publication
28237967 | J:242076
First Author: Poobalasingam T
Year: 2017
Journal: Dis Model Mech
Title: Heterozygous Vangl2Looptail mice reveal novel roles for the planar cell polarity pathway in adult lung homeostasis and repair.
Volume: 10
Issue: 4
Pages: 409-423
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Publication
22366192 | J:184926
First Author: Blackburn J
Year: 2012
Journal: Dev Biol
Title: The role of Irf6 in tooth epithelial invagination.
Volume: 365
Issue: 1
Pages: 61-70
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Publication
28400473 | J:242009
First Author: Choo MK
Year: 2017
Journal: J Exp Med
Title: TLR sensing of bacterial spore-associated RNA triggers host immune responses with detrimental effects.
Volume: 214
Issue: 5
Pages: 1297-1311
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Publication
- | J:58777
     
First Author: Elliott R
Year: 2000
Journal: Personal Communication
Title: Chromosome Locations Based on RH mapping
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Publication
- | J:147112
     
First Author: Taconic
Year: 2006
Journal: MGI Direct Data Submission
Title: Information obtained from Taconic website.
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
22988430 | J:190636
 
First Author: Wiese CB
Year: 2012
Journal: Front Neurosci
Title: A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.
Volume: 6
Pages: 130
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Publication
30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Pathway
R-MMU-9860276 | SLC15A4:TASL-dependent IRF5 activation
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Publication
28924041 | J:248506
First Author: Cushing L
Year: 2017
Journal: J Biol Chem
Title: IRAK4 kinase activity controls Toll-like receptor-induced inflammation through the transcription factor IRF5 in primary human monocytes.
Volume: 292
Issue: 45
Pages: 18689-18698
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Interaction Experiment
Heinz LX (2020)
Description: TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9.
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Publication
32433612 | -
First Author: Heinz LX
Year: 2020
Journal: Nature
Title: TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9.
Volume: 581
Issue: 7808
Pages: 316-322
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Allele
Irf5<em2Smoc> | MGI:7290580
Name: interferon regulatory factor 5; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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DO Term
DOID:0110895 | inflammatory bowel disease 14
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Interaction Experiment
Kim D (2017)
Description: Cytosolic Pellino-1-Mediated K63-Linked Ubiquitination of IRF5 in M1 Macrophages Regulates Glucose Intolerance in Obesity.
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Protein
Q9D3J9
Organism: Mus musculus/domesticus
Length: 298  
Fragment?: false
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Strain
MGI:6770865 | C57BL/6JSmoc-Irf5<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Irf5<em1Smoc> | MGI:7290579
Name: interferon regulatory factor 5; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Protein Coding Gene
MGI:1918648 | Tasl
Type: protein_coding_gene
Organism: mouse, laboratory
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Strain
MGI:6475611 | C57BL/6JSmoc-Irf5<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Protein Coding Gene
MGI:2140796 | Slc15a4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q91W98
Organism: Mus musculus/domesticus
Length: 574  
Fragment?: false
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Protein
Q8BHV4
Organism: Mus musculus/domesticus
Length: 303  
Fragment?: false
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Protein
A2ALN9
Organism: Mus musculus/domesticus
Length: 83  
Fragment?: true
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Protein
Q08EG0
Organism: Mus musculus/domesticus
Length: 298  
Fragment?: false
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Publication
31001245 | -
 
First Author: Harris VM
Year: 2019
Journal: Front Immunol
Title: Lysosomal pH Is Regulated in a Sex Dependent Manner in Immune Cells Expressing CXorf21.
Volume: 10
Pages: 578
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Protein Domain
IPR027869 | TASL
Type: Family
Description: In humans, TASL (TLR adaptor interacting with SLC15A4 on the lysosome) is encoded by CXorf21 that is associated with systemic lupus erythematosus []. It is an immune adaptor that is required for recruitment and activation of IRF5 by TLR7, TLR8 and TLR9, in mechanistic analogy to IRF3 and its three adaptors STING, MAVS and TRIF. TASL interacts with the endolysosomal transporter SLC15A4; the SLC15A4-TASL complex is required for endolysosomal TLR signalling. TASL contains a pLxIS motif that is important for its function [].
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Publication
31101814 | J:343419
First Author: Jiang SH
Year: 2019
Journal: Nat Commun
Title: Functional rare and low frequency variants in BLK and BANK1 contribute to human lupus.
Volume: 10
Issue: 1
Pages: 2201
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Publication
25813085 | J:221863
 
First Author: Lu G
Year: 2015
Journal: Nat Commun
Title: Myeloid cell-derived inducible nitric oxide synthase suppresses M1 macrophage polarization.
Volume: 6
Pages: 6676
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Publication
25565375 | J:219748
 
First Author: Jin J
Year: 2015
Journal: Nat Commun
Title: Proinflammatory TLR signalling is regulated by a TRAF2-dependent proteolysis mechanism in macrophages.
Volume: 6
Pages: 5930
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Publication
27210752 | J:231437
First Author: Mahajan VS
Year: 2016
Journal: Cell Rep
Title: Striking Immune Phenotypes in Gene-Targeted Mice Are Driven by a Copy-Number Variant Originating from a Commercially Available C57BL/6 Strain.
Volume: 15
Issue: 9
Pages: 1901-9
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Publication
23455675 | J:194820
First Author: McEwan WA
Year: 2013
Journal: Nat Immunol
Title: Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor TRIM21.
Volume: 14
Issue: 4
Pages: 327-36
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Publication
34282331 | J:321291
First Author: Khoyratty TE
Year: 2021
Journal: Nat Immunol
Title: Distinct transcription factor networks control neutrophil-driven inflammation.
Volume: 22
Issue: 9
Pages: 1093-1106
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Protein Coding Gene
MGI:99484 | Chuk
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1338071 | Ikbkb
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
O88351
Organism: Mus musculus/domesticus
Length: 757  
Fragment?: false
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Protein
Q60680
Organism: Mus musculus/domesticus
Length: 745  
Fragment?: false
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Publication
17018642 | J:115304
First Author: Negishi H
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program.
Volume: 103
Issue: 41
Pages: 15136-41
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Publication
30061415 | J:265082
First Author: Kayama H
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Heme ameliorates dextran sodium sulfate-induced colitis through providing intestinal macrophages with noninflammatory profiles.
Volume: 115
Issue: 33
Pages: 8418-8423
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Publication
21625574 | J:176091
First Author: Gratz N
Year: 2011
Journal: PLoS Pathog
Title: Type I interferon production induced by Streptococcus pyogenes-derived nucleic acids is required for host protection.
Volume: 7
Issue: 5
Pages: e1001345
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Publication
37872182 | J:343050
First Author: Li F
Year: 2023
Journal: Nat Commun
Title: C-type lectin receptor 2d forms homodimers and heterodimers with TLR2 to negatively regulate IRF5-mediated antifungal immunity.
Volume: 14
Issue: 1
Pages: 6718
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Publication
22547697 | J:188727
First Author: Lacey DC
Year: 2012
Journal: J Immunol
Title: Defining GM-CSF- and macrophage-CSF-dependent macrophage responses by in vitro models.
Volume: 188
Issue: 11
Pages: 5752-65
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Publication
32117252 | J:308212
 
First Author: Kunishita Y
Year: 2020
Journal: Front Immunol
Title: TRIM21 Dysfunction Enhances Aberrant B-Cell Differentiation in Autoimmune Pathogenesis.
Volume: 11
Pages: 98
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Protein Coding Gene
MGI:1338074 | Ikbkg
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
O88522
Organism: Mus musculus/domesticus
Length: 412  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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