| Type |
Details |
Score |
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| First Author: |
Slough J |
| Year: |
2008 |
| Journal: |
Dev Dyn |
| Title: |
Monocilia in the embryonic mouse heart suggest a direct role for cilia in cardiac morphogenesis. |
| Volume: |
237 |
| Issue: |
9 |
| Pages: |
2304-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Viau A |
| Year: |
2020 |
| Journal: |
J Am Soc Nephrol |
| Title: |
Tubular STAT3 Limits Renal Inflammation in Autosomal Dominant Polycystic Kidney Disease. |
| Volume: |
31 |
| Issue: |
5 |
| Pages: |
1035-1049 |
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•
•
•
•
|
| Publication |
| First Author: |
Snedeker J |
| Year: |
2017 |
| Journal: |
PLoS One |
| Title: |
Unique spatiotemporal requirements for intraflagellar transport genes during forebrain development. |
| Volume: |
12 |
| Issue: |
3 |
| Pages: |
e0173258 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Pennesi ME |
| Year: |
2003 |
| Journal: |
J Neurosci |
| Title: |
BETA2/NeuroD1 null mice: a new model for transcription factor-dependent photoreceptor degeneration. |
| Volume: |
23 |
| Issue: |
2 |
| Pages: |
453-61 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Schock EN |
| Year: |
2017 |
| Journal: |
PLoS One |
| Title: |
A tissue-specific role for intraflagellar transport genes during craniofacial development. |
| Volume: |
12 |
| Issue: |
3 |
| Pages: |
e0174206 |
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•
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•
•
•
|
| Publication |
| First Author: |
Galiano MR |
| Year: |
2012 |
| Journal: |
Cell |
| Title: |
A distal axonal cytoskeleton forms an intra-axonal boundary that controls axon initial segment assembly. |
| Volume: |
149 |
| Issue: |
5 |
| Pages: |
1125-39 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang C |
| Year: |
2021 |
| Journal: |
J Am Soc Nephrol |
| Title: |
Cyclin-Dependent Kinase 1 Activity Is a Driver of Cyst Growth in Polycystic Kidney Disease. |
| Volume: |
32 |
| Issue: |
1 |
| Pages: |
41-51 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Hiesberger T |
| Year: |
2004 |
| Journal: |
J Clin Invest |
| Title: |
Mutation of hepatocyte nuclear factor-1beta inhibits Pkhd1 gene expression and produces renal cysts in mice. |
| Volume: |
113 |
| Issue: |
6 |
| Pages: |
814-25 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Villalobos E |
| Year: |
2019 |
| Journal: |
Circulation |
| Title: |
Fibroblast Primary Cilia Are Required for Cardiac Fibrosis. |
| Volume: |
139 |
| Issue: |
20 |
| Pages: |
2342-2357 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee CH |
| Year: |
2020 |
| Journal: |
Nat Commun |
| Title: |
Primary cilia mediate early life programming of adiposity through lysosomal regulation in the developing mouse hypothalamus. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
5772 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Insinna C |
| Year: |
2009 |
| Journal: |
Dev Dyn |
| Title: |
Different roles for KIF17 and kinesin II in photoreceptor development and maintenance. |
| Volume: |
238 |
| Issue: |
9 |
| Pages: |
2211-22 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Honda A |
| Year: |
2018 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
FGFR1-mediated protocadherin-15 loading mediates cargo specificity during intraflagellar transport in inner ear hair-cell kinocilia. |
| Volume: |
115 |
| Issue: |
33 |
| Pages: |
8388-8393 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mahuzier A |
| Year: |
2018 |
| Journal: |
Nat Commun |
| Title: |
Ependymal cilia beating induces an actin network to protect centrioles against shear stress. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
2279 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Han YG |
| Year: |
2008 |
| Journal: |
Nat Neurosci |
| Title: |
Hedgehog signaling and primary cilia are required for the formation of adult neural stem cells. |
| Volume: |
11 |
| Issue: |
3 |
| Pages: |
277-84 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Raya A |
| Year: |
2003 |
| Journal: |
Genes Dev |
| Title: |
Notch activity induces Nodal expression and mediates the establishment of left-right asymmetry in vertebrate embryos. |
| Volume: |
17 |
| Issue: |
10 |
| Pages: |
1213-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jones C |
| Year: |
2008 |
| Journal: |
Nat Genet |
| Title: |
Ciliary proteins link basal body polarization to planar cell polarity regulation. |
| Volume: |
40 |
| Issue: |
1 |
| Pages: |
69-77 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Haycraft CJ |
| Year: |
2007 |
| Journal: |
Development |
| Title: |
Intraflagellar transport is essential for endochondral bone formation. |
| Volume: |
134 |
| Issue: |
2 |
| Pages: |
307-16 |
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•
•
•
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| Publication |
| First Author: |
Khonsari RH |
| Year: |
2013 |
| Journal: |
BMC Biol |
| Title: |
The buccohypophyseal canal is an ancestral vertebrate trait maintained by modulation in sonic hedgehog signaling. |
| Volume: |
11 |
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| Pages: |
27 |
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•
•
•
•
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| Publication |
| First Author: |
Song B |
| Year: |
2007 |
| Journal: |
Dev Biol |
| Title: |
Development of the post-natal growth plate requires intraflagellar transport proteins. |
| Volume: |
305 |
| Issue: |
1 |
| Pages: |
202-16 |
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•
•
•
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| Publication |
| First Author: |
Baudoin JP |
| Year: |
2012 |
| Journal: |
Neuron |
| Title: |
Tangentially migrating neurons assemble a primary cilium that promotes their reorientation to the cortical plate. |
| Volume: |
76 |
| Issue: |
6 |
| Pages: |
1108-22 |
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•
•
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| Publication |
| First Author: |
Golas A |
| Year: |
2008 |
| Journal: |
Int J Dev Biol |
| Title: |
Gene mapping of sperm quality parameters in recombinant inbred strains of mice. |
| Volume: |
52 |
| Issue: |
2-3 |
| Pages: |
287-93 |
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•
•
•
•
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| Publication |
| First Author: |
Omori Y |
| Year: |
2010 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Negative regulation of ciliary length by ciliary male germ cell-associated kinase (Mak) is required for retinal photoreceptor survival. |
| Volume: |
107 |
| Issue: |
52 |
| Pages: |
22671-6 |
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•
•
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| Publication |
| First Author: |
Grimes DT |
| Year: |
2016 |
| Journal: |
PLoS Genet |
| Title: |
Genetic Analysis Reveals a Hierarchy of Interactions between Polycystin-Encoding Genes and Genes Controlling Cilia Function during Left-Right Determination. |
| Volume: |
12 |
| Issue: |
6 |
| Pages: |
e1006070 |
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| Publication |
| First Author: |
Foerster P |
| Year: |
2017 |
| Journal: |
Development |
| Title: |
mTORC1 signaling and primary cilia are required for brain ventricle morphogenesis. |
| Volume: |
144 |
| Issue: |
2 |
| Pages: |
201-210 |
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| Publication |
| First Author: |
Botilde Y |
| Year: |
2013 |
| Journal: |
Dev Biol |
| Title: |
Cluap1 localizes preferentially to the base and tip of cilia and is required for ciliogenesis in the mouse embryo. |
| Volume: |
381 |
| Issue: |
1 |
| Pages: |
203-12 |
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•
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•
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| Publication |
| First Author: |
Croyle MJ |
| Year: |
2011 |
| Journal: |
Development |
| Title: |
Role of epidermal primary cilia in the homeostasis of skin and hair follicles. |
| Volume: |
138 |
| Issue: |
9 |
| Pages: |
1675-85 |
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| First Author: |
Cochrane CR |
| Year: |
2020 |
| Journal: |
J Clin Invest |
| Title: |
Trp53 and Rb1 regulate autophagy and ligand-dependent Hedgehog signaling. |
| Volume: |
130 |
| Issue: |
8 |
| Pages: |
4006-4018 |
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| First Author: |
Chang CF |
| Year: |
2016 |
| Journal: |
PLoS Genet |
| Title: |
Craniofacial Ciliopathies Reveal Specific Requirements for GLI Proteins during Development of the Facial Midline. |
| Volume: |
12 |
| Issue: |
11 |
| Pages: |
e1006351 |
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Cheng L |
| Year: |
2014 |
| Journal: |
Neuron |
| Title: |
Human CFEOM1 mutations attenuate KIF21A autoinhibition and cause oculomotor axon stalling. |
| Volume: |
82 |
| Issue: |
2 |
| Pages: |
334-49 |
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Wenderfer SE |
| Year: |
2000 |
| Journal: |
Genomics |
| Title: |
Identification of 40 genes on a 1-Mb contig around the IL-4 cytokine family gene cluster on mouse chromosome 11. |
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63 |
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354-73 |
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Huangfu D |
| Year: |
2005 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Cilia and Hedgehog responsiveness in the mouse. |
| Volume: |
102 |
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32 |
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11325-30 |
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| First Author: |
Chen MH |
| Year: |
2009 |
| Journal: |
Genes Dev |
| Title: |
Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved. |
| Volume: |
23 |
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16 |
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1910-28 |
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Fuller K |
| Year: |
2014 |
| Journal: |
Dev Biol |
| Title: |
Rab23 regulates Nodal signaling in vertebrate left-right patterning independently of the Hedgehog pathway. |
| Volume: |
391 |
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182-95 |
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Millington G |
| Year: |
2017 |
| Journal: |
Dev Biol |
| Title: |
Cilia-dependent GLI processing in neural crest cells is required for tongue development. |
| Volume: |
424 |
| Issue: |
2 |
| Pages: |
124-137 |
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Wang L |
| Year: |
2016 |
| Journal: |
Nat Neurosci |
| Title: |
Hedgehog signaling promotes basal progenitor expansion and the growth and folding of the neocortex. |
| Volume: |
19 |
| Issue: |
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888-96 |
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Schock EN |
| Year: |
2017 |
| Journal: |
Dev Biol |
| Title: |
Neural crest cells utilize primary cilia to regulate ventral forebrain morphogenesis via Hedgehog-dependent regulation of oriented cell division. |
| Volume: |
431 |
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Hum Mol Genet |
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The giant spectrin βV couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route. |
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Proc Natl Acad Sci U S A |
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Proc Natl Acad Sci U S A |
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The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling. |
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Mol Reprod Dev |
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Elliott KH |
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Dev Dyn |
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A novel role for cilia-dependent sonic hedgehog signaling during submandibular gland development. |
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Dev Neurobiol |
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Primary cilia and Gli3 activity regulate cerebral cortical size. |
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Goggolidou P |
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ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis. |
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Proc Natl Acad Sci U S A |
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Dev Cell |
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Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage. |
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Hum Mol Genet |
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Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling. |
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Dev Biol |
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FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism. |
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| UniProt Feature |
| Begin: |
1 |
| Description: |
Kinesin-like protein KIF3A |
| Type: |
chain |
| End: |
701 |
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A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis. |
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2022 |
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| Title: |
Cyagen Biosciences Website. |
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| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
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| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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| Publication |
| First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
| Year: |
2004 |
| Journal: |
Database Release |
| Title: |
Mouse T31 Radiation Hybrid Data Load |
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| Publication |
| First Author: |
Okazaki Y |
| Year: |
2002 |
| Journal: |
Nature |
| Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
| Volume: |
420 |
| Issue: |
6915 |
| Pages: |
563-73 |
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| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
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| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
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| Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
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| Title: |
Annotation inferences using phylogenetic trees |
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| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
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| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
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| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
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| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
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| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
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| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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| Publication |
| First Author: |
Chen JL |
| Year: |
2019 |
| Journal: |
Cereb Cortex |
| Title: |
Gli2 Rescues Delays in Brain Development Induced by Kif3a Dysfunction. |
| Volume: |
29 |
| Issue: |
2 |
| Pages: |
751-764 |
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
701
 |
| Fragment?: |
false |
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
178
 |
| Fragment?: |
true |
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
185
 |
| Fragment?: |
true |
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
25
 |
| Fragment?: |
true |
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| GXD Expression |
| Probe: |
MGI:6794084 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-11-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268121 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:6794088 |
| Age: |
embryonic day 13.5 |
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| Note: |
Coexpression with Kif3a in postmitotic territories. |
| Specimen Label: |
2e |
| Detected: |
true |
| Specimen Num: |
3 |
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•
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•
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| GXD Expression |
| Probe: |
MGI:6794084 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-11-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268121 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:6794088 |
| Age: |
embryonic day 13.5 |
|
| Note: |
Coexpression with Kif3a in postmitotic territories. |
| Specimen Label: |
2m |
| Detected: |
true |
| Specimen Num: |
5 |
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•
•
•
•
•
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| GXD Expression |
| Probe: |
MGI:6794084 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-11-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1758021 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:6794088 |
| Age: |
embryonic day 13.5 |
|
| Note: |
Coexpression with Kif3a in postmitotic territories. |
| Specimen Label: |
2e |
| Detected: |
true |
| Specimen Num: |
3 |
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•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6794084 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2021-11-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1758021 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:6794088 |
| Age: |
embryonic day 13.5 |
|
| Note: |
Coexpression with Kif3a in postmitotic territories. |
| Specimen Label: |
2m |
| Detected: |
true |
| Specimen Num: |
5 |
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| Interaction Experiment |
| Description: |
The Axin/TNKS complex interacts with KIF3A and is required for insulin-stimulated GLUT4 translocation. |
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•
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| Publication |
| First Author: |
Guo HL |
| Year: |
2012 |
| Journal: |
Cell Res |
| Title: |
The Axin/TNKS complex interacts with KIF3A and is required for insulin-stimulated GLUT4 translocation. |
| Volume: |
22 |
| Issue: |
8 |
| Pages: |
1246-57 |
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| HT Experiment |
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| Experiment Type: |
RNA-Seq |
| Study Type: |
WT vs. Mutant |
| Source: |
GEO |
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•
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•
•
•
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| Allele |
| Name: |
Kruppel-like transcription factor 3 (basic); targeted mutation 1, Pumin Zhang |
| Allele Type: |
Targeted |
| Attribute String: |
Inducible, Recombinase |
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