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Search results 201 to 281 out of 281 for Klhl5

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_04
Specimen Label: euxassay_012137_04
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_05
Specimen Label: euxassay_012137_05
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_06
Specimen Label: euxassay_012137_06
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_07
Specimen Label: euxassay_012137_07
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_14
Specimen Label: euxassay_012137_14
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_15
Specimen Label: euxassay_012137_15
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_16
Specimen Label: euxassay_012137_16
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_17
Specimen Label: euxassay_012137_17
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_18
Specimen Label: euxassay_012137_18
Detected: true
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_19
Specimen Label: euxassay_012137_19
Detected: true
Specimen Num: 19
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3507348
Assay Type: RNA in situ
Annotation Date: 2005-01-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754021
Pattern: Single cells
Stage: TS21
Assay Id: MGI:3512665
Age: embryonic day 13.5
Note: Expression was detected in some cells.
Specimen Label: 1
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507348
Assay Type: RNA in situ
Annotation Date: 2005-01-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754027
Stage: TS27
Assay Id: MGI:3512665
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507348
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5540266
Age: embryonic day 15.5
Image: GUDMAP:6455
Specimen Label: GUDMAP:6455
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3507348
Assay Type: RNA in situ
Annotation Date: 2005-01-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3280927
Stage: TS27
Assay Id: MGI:3512665
Age: postnatal newborn
Image: 2
Note: The tissue was olfactory epithelium and/or bulb.
Specimen Label: 2
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1745423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_01
Specimen Label: euxassay_012137_01
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1745423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_02
Specimen Label: euxassay_012137_02
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_03
Specimen Label: euxassay_012137_03
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3507348
Assay Type: RNA in situ
Annotation Date: 2005-01-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267921
Pattern: Single cells
Stage: TS21
Assay Id: MGI:3512665
Age: embryonic day 13.5
Note: Expression was detected in some cells.
Specimen Label: 1
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507348
Assay Type: RNA in situ
Annotation Date: 2005-01-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3267927
Stage: TS27
Assay Id: MGI:3512665
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507348
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5540266
Age: embryonic day 15.5
Image: GUDMAP:6455
Specimen Label: GUDMAP:6455
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507348
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2874723
Stage: TS23
Assay Id: MGI:5540266
Age: embryonic day 15.5
Image: GUDMAP:6455
Specimen Label: GUDMAP:6455
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_09
Specimen Label: euxassay_012137_09
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_10
Specimen Label: euxassay_012137_10
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_11
Specimen Label: euxassay_012137_11
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_14
Specimen Label: euxassay_012137_14
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_15
Specimen Label: euxassay_012137_15
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_16
Specimen Label: euxassay_012137_16
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3507348
Assay Type: RNA in situ
Annotation Date: 2005-01-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757721
Stage: TS21
Assay Id: MGI:3512665
Age: embryonic day 13.5
Specimen Label: 1
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507348
Assay Type: RNA in situ
Annotation Date: 2005-01-04
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:3512665
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3281228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691967
Age: postnatal adult
Image: CCP-IMG_2127265
Specimen Label: CCP-IMG_2127265
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3281228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691967
Age: postnatal adult
Image: CCP-IMG_2127257
Specimen Label: CCP-IMG_2127257
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3507348
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5540266
Age: embryonic day 15.5
Image: GUDMAP:6455
Specimen Label: GUDMAP:6455
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_04
Specimen Label: euxassay_012137_04
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_06
Specimen Label: euxassay_012137_06
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_07
Specimen Label: euxassay_012137_07
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_08
Specimen Label: euxassay_012137_08
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_09
Specimen Label: euxassay_012137_09
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_10
Specimen Label: euxassay_012137_10
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4417737
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1755623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825805
Age: embryonic day 14.5
Image: euxassay_012137_11
Specimen Label: euxassay_012137_11
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3507348
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540266
Age: embryonic day 15.5
Image: GUDMAP:6455
Specimen Label: GUDMAP:6455
Detected: true
Specimen Num: 1
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•
Publication
19521500 | J:149737
First Author: Sansom SN
Year: 2009
Journal: PLoS Genet
Title: The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.
Volume: 5
Issue: 6
Pages: e1000511
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
- | J:73796
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
11590829 | -
First Author: Wang S
Year: 2001
Journal: Biochem Genet
Title: Cloning and characterization of KLHL5, a novel human gene encoding a kelch-related protein with a BTB domain.
Volume: 39
Issue: 7-8
Pages: 227-38
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Protein Domain
IPR030606 | KLHL5_BTB/POZ
Type: Domain
Description: This entry represents the BTB/POZ domain found in Kelch-like protein 5 (KLHL5), which belongs to the KLHL family []. The function of KLHL5 is not clear [].The KLHL (Kelch-like) proteins generally have a BTB/POZ domain, a BACK domain, and five to six Kelch motifs. They constitute a subgroup at the intersection between the BTB/POZ domain and Kelch domain superfamilies. The BTB/POZ domain facilitates protein binding [], while the Kelch domain (repeats) form β-propellers. The Kelch superfamily of proteins can be subdivided into five groups: (1) N-propeller, C-dimer proteins, (2) N-propeller proteins, (3) propeller proteins, (4) N-dimer, C-propeller proteins, and (5) C-propeller proteins. KLHL family members belong to the N-dimer, C-propeller subclass of Kelch repeat proteins []. In addition to BTB/POZ and Kelch domains, the KLHL family members contain a BACK domain, first described as a 130-residue region of conservation observed amongst BTB-Kelch proteins []. Many of the Kelch-like proteins have been identified as adaptors for the recruitment of substrates to Cul3-based E3 ubiquitin ligases [, ].
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Protein
E9Q1L2
Organism: Mus musculus/domesticus
Length: 568  
Fragment?: false
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Protein
Q571J4
Organism: Mus musculus/domesticus
Length: 649  
Fragment?: true
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Publication
10603472 | -
First Author: Adams J
Year: 2000
Journal: Trends Cell Biol
Title: The kelch repeat superfamily of proteins: propellers of cell function.
Volume: 10
Issue: 1
Pages: 17-24
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Publication
14528312 | -
First Author: Furukawa M
Year: 2003
Journal: Nat Cell Biol
Title: Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases.
Volume: 5
Issue: 11
Pages: 1001-7
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Publication
23135275 | -
First Author: Oberg EA
Year: 2012
Journal: J Biol Chem
Title: Selective proteasomal degradation of the B'β subunit of protein phosphatase 2A by the E3 ubiquitin ligase adaptor Kelch-like 15.
Volume: 287
Issue: 52
Pages: 43378-89
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Publication
15544948 | -
First Author: Stogios PJ
Year: 2004
Journal: Trends Biochem Sci
Title: The BACK domain in BTB-kelch proteins.
Volume: 29
Issue: 12
Pages: 634-7
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Publication
23676014 | -
 
First Author: Dhanoa BS
Year: 2013
Journal: Hum Genomics
Title: Update on the Kelch-like (KLHL) gene family.
Volume: 7
Pages: 13
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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