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Search results 201 to 300 out of 3295 for Kras

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Type Details Score
Publication
First Author: Ambrogio C
Year: 2016
Journal: Nat Med
Title: Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma.
Volume: 22
Issue: 3
Pages: 270-7
Publication
First Author: Shi G
Year: 2009
Journal: Gastroenterology
Title: Loss of the acinar-restricted transcription factor Mist1 accelerates Kras-induced pancreatic intraepithelial neoplasia.
Volume: 136
Issue: 4
Pages: 1368-78
Publication
First Author: Doyle B
Year: 2010
Journal: J Pathol
Title: p53 mutation and loss have different effects on tumourigenesis in a novel mouse model of pleomorphic rhabdomyosarcoma.
Volume: 222
Issue: 2
Pages: 129-37
Publication
First Author: Khalaileh A
Year: 2013
Journal: Cancer Res
Title: Phosphorylation of ribosomal protein S6 attenuates DNA damage and tumor suppression during development of pancreatic cancer.
Volume: 73
Issue: 6
Pages: 1811-20
Publication
First Author: Luo F
Year: 2011
Journal: J Pathol
Title: Mutant K-ras promotes carcinogen-induced murine colorectal tumourigenesis, but does not alter tumour chromosome stability.
Volume: 223
Issue: 3
Pages: 390-9
Publication
First Author: Potenza N
Year: 2005
Journal: EMBO Rep
Title: Replacement of K-Ras with H-Ras supports normal embryonic development despite inducing cardiovascular pathology in adult mice.
Volume: 6
Issue: 5
Pages: 432-7
Publication
First Author: Hernández-Porras I
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: K-RasV14I recapitulates Noonan syndrome in mice.
Volume: 111
Issue: 46
Pages: 16395-400
Publication
First Author: Kun EHS
Year: 2020
Journal: Sci Rep
Title: Differences in gynecologic tumor development in Amhr2-Cre mice with KRASG12D or KRASG12V mutations.
Volume: 10
Issue: 1
Pages: 20678
Publication
First Author: Wu J
Year: 2017
Journal: PLoS One
Title: Generation of a pancreatic cancer model using a Pdx1-Flp recombinase knock-in allele.
Volume: 12
Issue: 9
Pages: e0184984
Publication
First Author: Dey P
Year: 2020
Journal: Cancer Discov
Title: Oncogenic KRAS-Driven Metabolic Reprogramming in Pancreatic Cancer Cells Utilizes Cytokines from the Tumor Microenvironment.
Volume: 10
Issue: 4
Pages: 608-625
Publication
First Author: Yao W
Year: 2019
Journal: Nature
Title: Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer.
Volume: 568
Issue: 7752
Pages: 410-414
Publication
First Author: Hilkens J
Year: 2017
Journal: Gut
Title: RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis.
Volume: 66
Issue: 6
Pages: 1095-1105
HT Experiment  
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication  
First Author: Lefler JE
Year: 2022
Journal: Life Sci Alliance
Title: STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer.
Volume: 5
Issue: 11
Publication
First Author: George DL
Year: 1985
Journal: EMBO J
Title: Structure and expression of amplified cKi-ras gene sequences in Y1 mouse adrenal tumor cells.
Volume: 4
Issue: 5
Pages: 1199-203
Publication
First Author: Rädler PD
Year: 2021
Journal: Nat Commun
Title: Highly metastatic claudin-low mammary cancers can originate from luminal epithelial cells.
Volume: 12
Issue: 1
Pages: 3742
Publication  
First Author: Tuveson DA
Year: 2005
Journal: Cold Spring Harb Symp Quant Biol
Title: Ductal pancreatic cancer in humans and mice.
Volume: 70
Pages: 65-72
Publication
First Author: Ambrogio C
Year: 2014
Journal: Cancer Res
Title: Modeling lung cancer evolution and preclinical response by orthotopic mouse allografts.
Volume: 74
Issue: 21
Pages: 5978-88
Publication
First Author: Micucci C
Year: 2014
Journal: PLoS One
Title: Hyperglycemia promotes K-Ras-induced lung tumorigenesis through BASCs amplification.
Volume: 9
Issue: 8
Pages: e105550
Publication  
First Author: Kirschner LS
Year: 2016
Journal: Mol Cell Endocrinol
Title: Mouse models of thyroid cancer: A 2015 update.
Volume: 421
Pages: 18-27
Publication
First Author: Viale A
Year: 2014
Journal: Nature
Title: Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function.
Volume: 514
Issue: 7524
Pages: 628-32
Publication
First Author: Luo F
Year: 2011
Journal: Oncol Rep
Title: Synergism between K-rasVal12 and mutant Apc accelerates murine large intestinal tumourigenesis.
Volume: 26
Issue: 1
Pages: 125-33
Publication
First Author: Muñoz-Lorente MA
Year: 2018
Journal: PLoS Genet
Title: AAV9-mediated telomerase activation does not accelerate tumorigenesis in the context of oncogenic K-Ras-induced lung cancer.
Volume: 14
Issue: 8
Pages: e1007562
Publication
First Author: Chiao PJ
Year: 2011
Journal: Cancer Discov
Title: Kras, Pten, NF-κB, and inflammation: dangerous liaisons.
Volume: 1
Issue: 2
Pages: 103-5
Publication
First Author: Milagre C
Year: 2010
Journal: Cancer Res
Title: A mouse model of melanoma driven by oncogenic KRAS.
Volume: 70
Issue: 13
Pages: 5549-57
Publication
First Author: Carrière C
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Acute pancreatitis markedly accelerates pancreatic cancer progression in mice expressing oncogenic Kras.
Volume: 382
Issue: 3
Pages: 561-5
Publication
First Author: Wang MT
Year: 2015
Journal: Cell
Title: K-Ras Promotes Tumorigenicity through Suppression of Non-canonical Wnt Signaling.
Volume: 163
Issue: 5
Pages: 1237-1251
Publication
First Author: Martínez-Romero C
Year: 2009
Journal: J Pathol
Title: The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma.
Volume: 219
Issue: 2
Pages: 205-13
Publication
First Author: Youn JI
Year: 2013
Journal: Nat Immunol
Title: Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer.
Volume: 14
Issue: 3
Pages: 211-20
Publication
First Author: Mainardi S
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Identification of cancer initiating cells in K-Ras driven lung adenocarcinoma.
Volume: 111
Issue: 1
Pages: 255-60
Publication  
First Author: Costa-Machado LF
Year: 2018
Journal: EMBO Rep
Title: Sirt1 protects from K-Ras-driven lung carcinogenesis.
Volume: 19
Issue: 9
Publication
First Author: Cheng CW
Year: 2011
Journal: J Pathol
Title: Activation of mutated K-ras in donor endometrial epithelium and stroma promotes lesion growth in an intact immunocompetent murine model of endometriosis.
Volume: 224
Issue: 2
Pages: 261-9
Publication  
First Author: Kim CF
Year: 2005
Journal: Cold Spring Harb Symp Quant Biol
Title: Mouse models of human non-small-cell lung cancer: raising the bar.
Volume: 70
Pages: 241-50
Publication
First Author: Pedrosa P
Year: 2024
Journal: Cell Death Dis
Title: Inhibition of lung tumorigenesis by transient reprogramming in cancer cells.
Volume: 15
Issue: 11
Pages: 857
Publication
First Author: Papaioannou G
Year: 2016
Journal: Cell Death Dis
Title: Ras signaling regulates osteoprogenitor cell proliferation and bone formation.
Volume: 7
Issue: 10
Pages: e2405
Publication
First Author: Pasca di Magliano M
Year: 2007
Journal: PLoS One
Title: Common activation of canonical Wnt signaling in pancreatic adenocarcinoma.
Volume: 2
Issue: 11
Pages: e1155
Publication
First Author: Fang L
Year: 2022
Journal: Cancer Gene Ther
Title: TMPRSS2-ERG promotes the initiation of prostate cancer by suppressing oncogene-induced senescence.
Volume: 29
Issue: 10
Pages: 1463-1476
Publication
First Author: Yang Z
Year: 2021
Journal: Nat Commun
Title: USP12 downregulation orchestrates a protumourigenic microenvironment and enhances lung tumour resistance to PD-1 blockade.
Volume: 12
Issue: 1
Pages: 4852
Publication
First Author: Luo L
Year: 2020
Journal: J Immunol
Title: Kras-Deficient T Cells Attenuate Graft-versus-Host Disease but Retain Graft-versus-Leukemia Activity.
Volume: 205
Issue: 12
Pages: 3480-3490
Publication
First Author: Kent OA
Year: 2010
Journal: Genes Dev
Title: Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway.
Volume: 24
Issue: 24
Pages: 2754-9
Publication
First Author: Szpirer J
Year: 1985
Journal: Somat Cell Mol Genet
Title: Assignment of three rat cellular RAS oncogenes to chromosomes 1, 4, and X.
Volume: 11
Issue: 1
Pages: 93-7
Publication
First Author: Genovese G
Year: 2017
Journal: Nature
Title: Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer.
Volume: 542
Issue: 7641
Pages: 362-366
Publication
First Author: Mijimolle N
Year: 2005
Journal: Cancer Cell
Title: Protein farnesyltransferase in embryogenesis, adult homeostasis, and tumor development.
Volume: 7
Issue: 4
Pages: 313-24
Publication
First Author: Ochi A
Year: 2012
Journal: J Clin Invest
Title: Toll-like receptor 7 regulates pancreatic carcinogenesis in mice and humans.
Volume: 122
Issue: 11
Pages: 4118-29
Publication
First Author: Alvarez R
Year: 2013
Journal: Br J Cancer
Title: Stromal disrupting effects of nab-paclitaxel in pancreatic cancer.
Volume: 109
Issue: 4
Pages: 926-33
Publication
First Author: Guerra C
Year: 2011
Journal: Cancer Cell
Title: Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence.
Volume: 19
Issue: 6
Pages: 728-39
Publication
First Author: Arora M
Year: 2023
Journal: Cell
Title: Rapid adaptation to CDK2 inhibition exposes intrinsic cell-cycle plasticity.
Volume: 186
Issue: 12
Pages: 2628-2643.e21
Publication  
First Author: Li K
Year: 2021
Journal: J Exp Med
Title: E3 ligase MKRN3 is a tumor suppressor regulating PABPC1 ubiquitination in non-small cell lung cancer.
Volume: 218
Issue: 8
Publication  
First Author: Döppler H
Year: 2016
Journal: Sci Rep
Title: The PRKD1 promoter is a target of the KRas-NF-κB pathway in pancreatic cancer.
Volume: 6
Pages: 33758
Publication
First Author: Sweet-Cordero A
Year: 2006
Journal: Genes Chromosomes Cancer
Title: Comparison of gene expression and DNA copy number changes in a murine model of lung cancer.
Volume: 45
Issue: 4
Pages: 338-48
Publication
First Author: To MD
Year: 2011
Journal: Mol Cancer Res
Title: Progressive genomic instability in the FVB/Kras(LA2) mouse model of lung cancer.
Volume: 9
Issue: 10
Pages: 1339-45
Publication
First Author: Park J
Year: 2019
Journal: Sci Rep
Title: A Ras destabilizer KYA1797K overcomes the resistance of EGFR tyrosine kinase inhibitor in KRAS-mutated non-small cell lung cancer.
Volume: 9
Issue: 1
Pages: 648
Publication
First Author: Dalin MG
Year: 2014
Journal: Cardiovasc Res
Title: Myocardial KRAS(G12D) expression does not cause cardiomyopathy in mice.
Volume: 101
Issue: 2
Pages: 229-35
Publication  
First Author: Li K
Year: 2022
Journal: J Clin Invest
Title: BCL6 is regulated by the MAPK/ELK1 axis and promotes KRAS-driven lung cancer.
Volume: 132
Issue: 22
Publication
First Author: Seguin L
Year: 2017
Journal: Cancer Discov
Title: Galectin-3, a Druggable Vulnerability for KRAS-Addicted Cancers.
Volume: 7
Issue: 12
Pages: 1464-1479
Publication  
First Author: Kruspig B
Year: 2018
Journal: Sci Transl Med
Title: The ERBB network facilitates KRAS-driven lung tumorigenesis.
Volume: 10
Issue: 446
Publication  
First Author: Zhang H
Year: 2015
Journal: Sci Rep
Title: Identification of urine protein biomarkers with the potential for early detection of lung cancer.
Volume: 5
Pages: 11805
Publication
First Author: Gier B
Year: 2012
Journal: Diabetes
Title: Chronic GLP-1 receptor activation by exendin-4 induces expansion of pancreatic duct glands in rats and accelerates formation of dysplastic lesions and chronic pancreatitis in the Kras(G12D) mouse model.
Volume: 61
Issue: 5
Pages: 1250-62
Publication
First Author: Weisberg E
Year: 2015
Journal: Leukemia
Title: Identification of Wee1 as a novel therapeutic target for mutant RAS-driven acute leukemia and other malignancies.
Volume: 29
Issue: 1
Pages: 27-37
Publication
First Author: Cho HC
Year: 2011
Journal: Cancer Res
Title: Identification of tumorigenic cells in Kras(G12D)-induced lung adenocarcinoma.
Volume: 71
Issue: 23
Pages: 7250-8
Publication  
First Author: Majeti BK
Year: 2013
Journal: BMC Cancer
Title: VEGF is an important mediator of tumor angiogenesis in malignant lesions in a genetically engineered mouse model of lung adenocarcinoma.
Volume: 13
Pages: 213
Publication
First Author: Xia Y
Year: 2014
Journal: Sci Transl Med
Title: A combination therapy for KRAS-driven lung adenocarcinomas using lipophilic bisphosphonates and rapamycin.
Volume: 6
Issue: 263
Pages: 263ra161
Publication
First Author: Gades NM
Year: 2008
Journal: Comp Med
Title: Spontaneous vulvar papillomas in a colony of mice used for pancreatic cancer research.
Volume: 58
Issue: 3
Pages: 271-5
Publication
First Author: Nishimura M
Year: 1999
Journal: Radiat Res
Title: Low frequency of Ras gene mutation in spontaneous and gamma-ray-induced thymic lymphomas of scid mice.
Volume: 151
Issue: 2
Pages: 142-9
Publication
First Author: Dassano A
Year: 2014
Journal: PLoS Genet
Title: Mouse pulmonary adenoma susceptibility 1 locus is an expression QTL modulating Kras-4A.
Volume: 10
Issue: 4
Pages: e1004307
Publication
First Author: Cotroneo CE
Year: 2016
Journal: Cancer Lett
Title: Expression quantitative trait analysis reveals fine germline transcript regulation in mouse lung tumors.
Volume: 375
Issue: 2
Pages: 221-230
Publication
First Author: Zhang J
Year: 2009
Journal: Blood
Title: Oncogenic Kras-induced leukemogeneis: hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation.
Volume: 113
Issue: 6
Pages: 1304-14
Publication
First Author: Huang J
Year: 2019
Journal: Sci Rep
Title: Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous KrasG12D.
Volume: 9
Issue: 1
Pages: 17220
Publication
First Author: Wang D
Year: 2019
Journal: Cell Commun Signal
Title: Obesogenic high-fat diet heightens aerobic glycolysis through hyperactivation of oncogenic KRAS.
Volume: 17
Issue: 1
Pages: 19
Publication
First Author: Melo SA
Year: 2015
Journal: Nature
Title: Glypican-1 identifies cancer exosomes and detects early pancreatic cancer.
Volume: 523
Issue: 7559
Pages: 177-82
Publication
First Author: Fuentes NR
Year: 2018
Journal: Cancer Res
Title: Long-Chain n-3 Fatty Acids Attenuate Oncogenic KRas-Driven Proliferation by Altering Plasma Membrane Nanoscale Proteolipid Composition.
Volume: 78
Issue: 14
Pages: 3899-3912
Publication
First Author: Le Roux Ö
Year: 2024
Journal: PLoS One
Title: p53 dosage can impede KrasG12D- and KrasQ61R-mediated tumorigenesis.
Volume: 19
Issue: 3
Pages: e0292189
Publication
First Author: Joshi J
Year: 2008
Journal: EMBO J
Title: Par-4 inhibits Akt and suppresses Ras-induced lung tumorigenesis.
Volume: 27
Issue: 16
Pages: 2181-93
Publication  
First Author: Simin K
Year: 2005
Journal: Cold Spring Harb Symp Quant Biol
Title: Deciphering cancer complexities in genetically engineered mice.
Volume: 70
Pages: 283-90
Publication
First Author: Zhang Y
Year: 2009
Journal: Blood
Title: MLL5 contributes to hematopoietic stem cell fitness and homeostasis.
Volume: 113
Issue: 7
Pages: 1455-63
Publication
First Author: Carrière C
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia.
Volume: 104
Issue: 11
Pages: 4437-42
Publication
First Author: Zheng C
Year: 2017
Journal: Sci Rep
Title: Cell Division Cycle 42 plays a Cell type-Specific role in Lung Tumorigenesis.
Volume: 7
Issue: 1
Pages: 10407
Publication  
First Author: O'Brien VP
Year: 2021
Journal: Life Sci Alliance
Title: Sustained Helicobacter pylori infection accelerates gastric dysplasia in a mouse model.
Volume: 4
Issue: 2
Publication  
First Author: Koh CP
Year: 2023
Journal: Gene
Title: Highly efficient Runx1 enhancer eR1-mediated genetic engineering for fetal, child and adult hematopoietic stem cells.
Volume: 851
Pages: 147049
Publication
First Author: Wang IC
Year: 2012
Journal: Mol Cell Biol
Title: Foxm1 mediates cross talk between Kras/mitogen-activated protein kinase and canonical Wnt pathways during development of respiratory epithelium.
Volume: 32
Issue: 19
Pages: 3838-50
Publication
First Author: Wei D
Year: 2016
Journal: Cancer Cell
Title: KLF4 Is Essential for Induction of Cellular Identity Change and Acinar-to-Ductal Reprogramming during Early Pancreatic Carcinogenesis.
Volume: 29
Issue: 3
Pages: 324-38
Publication
First Author: Hamarsheh S
Year: 2020
Journal: Nat Commun
Title: Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation.
Volume: 11
Issue: 1
Pages: 1659
Publication
First Author: Erener S
Year: 2021
Journal: Cell Rep Med
Title: Deletion of pancreas-specific miR-216a reduces beta-cell mass and inhibits pancreatic cancer progression in mice.
Volume: 2
Issue: 11
Pages: 100434
Publication
First Author: Krah NM
Year: 2019
Journal: Dev Cell
Title: Prevention and Reversion of Pancreatic Tumorigenesis through a Differentiation-Based Mechanism.
Volume: 50
Issue: 6
Pages: 744-754.e4
Publication
First Author: Falvo DJ
Year: 2023
Journal: Dev Cell
Title: A reversible epigenetic memory of inflammatory injury controls lineage plasticity and tumor initiation in the mouse pancreas.
Volume: 58
Issue: 24
Pages: 2959-2973.e7
Publication
First Author: Liou GY
Year: 2016
Journal: Cell Rep
Title: Mutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions.
Volume: 14
Issue: 10
Pages: 2325-36
Publication
First Author: Kumar MS
Year: 2012
Journal: Cell
Title: The GATA2 transcriptional network is requisite for RAS oncogene-driven non-small cell lung cancer.
Volume: 149
Issue: 3
Pages: 642-55
Publication
First Author: Zhang Q
Year: 2016
Journal: Neoplasia
Title: Fbxw7 Deletion Accelerates KrasG12D-Driven Pancreatic Tumorigenesis via Yap Accumulation.
Volume: 18
Issue: 11
Pages: 666-673
Publication
First Author: Zhao P
Year: 2013
Journal: Oncogene
Title: CD44 promotes Kras-dependent lung adenocarcinoma.
Volume: 32
Issue: 43
Pages: 5186-90
Publication
First Author: Blair LM
Year: 2023
Journal: Nat Commun
Title: Oncogenic context shapes the fitness landscape of tumor suppression.
Volume: 14
Issue: 1
Pages: 6422
Publication
First Author: Zhou C
Year: 2024
Journal: Nat Commun
Title: Mutant KRAS-activated circATXN7 fosters tumor immunoescape by sensitizing tumor-specific T cells to activation-induced cell death.
Volume: 15
Issue: 1
Pages: 499
Publication
First Author: Kadur Lakshminarasimha Murthy P
Year: 2022
Journal: Dev Cell
Title: Epigenetic basis of oncogenic-Kras-mediated epithelial-cellular proliferation and plasticity.
Volume: 57
Issue: 3
Pages: 310-328.e9
Publication
First Author: Liu X
Year: 2023
Journal: Oncogene
Title: CUL4B functions as a tumor suppressor in KRAS-driven lung tumors by inhibiting the recruitment of myeloid-derived suppressor cells.
Volume: 42
Issue: 42
Pages: 3113-3126
Publication
First Author: Stallings RL
Year: 1986
Journal: Cytogenet Cell Genet
Title: Assignment of RAS proto-oncogenes in Chinese hamsters: implications for mammalian gene linkage conservation and neoplasia.
Volume: 43
Issue: 1-2
Pages: 2-5
Publication
First Author: Saliakoura M
Year: 2020
Journal: Nat Cell Biol
Title: PLCγ1 suppression promotes the adaptation of KRAS-mutant lung adenocarcinomas to hypoxia.
Volume: 22
Issue: 11
Pages: 1382-1395
Publication
First Author: Lan T
Year: 2024
Journal: Nat Commun
Title: Glucose-6-phosphate dehydrogenase maintains redox homeostasis and biosynthesis in LKB1-deficient KRAS-driven lung cancer.
Volume: 15
Issue: 1
Pages: 5857
Publication
First Author: Hara T
Year: 2019
Journal: Cancer Res
Title: Modeling Gliomas Using Two Recombinases.
Volume: 79
Issue: 15
Pages: 3983-3991
Publication
First Author: Cellurale C
Year: 2011
Journal: Mol Cell Biol
Title: Requirement of c-Jun NH(2)-terminal kinase for Ras-initiated tumor formation.
Volume: 31
Issue: 7
Pages: 1565-76
Publication
First Author: Ardito CM
Year: 2012
Journal: Cancer Cell
Title: EGF receptor is required for KRAS-induced pancreatic tumorigenesis.
Volume: 22
Issue: 3
Pages: 304-17
Publication
First Author: Blasco MT
Year: 2019
Journal: Cancer Cell
Title: Complete Regression of Advanced Pancreatic Ductal Adenocarcinomas upon Combined Inhibition of EGFR and C-RAF.
Volume: 35
Issue: 4
Pages: 573-587.e6