| Type |
Details |
Score |
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
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•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
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|
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•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
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•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
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•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
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•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE14813 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chiyomaru T |
| Year: |
2012 |
| Journal: |
Urol Oncol |
| Title: |
Functional role of LASP1 in cell viability and its regulation by microRNAs in bladder cancer. |
| Volume: |
30 |
| Issue: |
4 |
| Pages: |
434-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li B |
| Year: |
2004 |
| Journal: |
J Biol Chem |
| Title: |
Zyxin interacts with the SH3 domains of the cytoskeletal proteins LIM-nebulette and Lasp-1. |
| Volume: |
279 |
| Issue: |
19 |
| Pages: |
20401-10 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Raman D |
| Year: |
2010 |
| Journal: |
PLoS One |
| Title: |
LIM and SH3 protein-1 modulates CXCR2-mediated cell migration. |
| Volume: |
5 |
| Issue: |
4 |
| Pages: |
e10050 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Grunewald TG |
| Year: |
2007 |
| Journal: |
BMC Cancer |
| Title: |
Nuclear localization and cytosolic overexpression of LASP-1 correlates with tumor size and nodal-positivity of human breast carcinoma. |
| Volume: |
7 |
|
| Pages: |
198 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Frietsch JJ |
| Year: |
2010 |
| Journal: |
Br J Cancer |
| Title: |
Nuclear localisation of LASP-1 correlates with poor long-term survival in female breast cancer. |
| Volume: |
102 |
| Issue: |
11 |
| Pages: |
1645-53 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang H |
| Year: |
2013 |
| Journal: |
Eur J Cancer |
| Title: |
LIM and SH3 protein 1, a promoter of cell proliferation and migration, is a novel independent prognostic indicator in hepatocellular carcinoma. |
| Volume: |
49 |
| Issue: |
4 |
| Pages: |
974-83 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
Lasp1 (LIM and SH3 domain protein 1) is a cytoplasmic protein that binds focal adhesion proteins and is involved in cell signaling, migration, and proliferation []. It is overexpressed in several cancer cells, including breast, ovarian, bladder, and liver [, , ]. In some cancer cells, it can be found in the nucleus; its degree of nuclear localization correlates with tumour size and poor prognosis []. Lasp1 is a 36kDa protein containing an N-terminal LIM domain, two nebulin repeats, and a C-terminal SH3 domain []. This entry represent the SH3 domain. |
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•
•
•
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•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
263
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
263
 |
| Fragment?: |
false |
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•
•
•
•
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