Type |
Details |
Score |
Allele |
Name: |
LIM domain only 7; targeted mutation 1, Shirley M Tilghman |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Lmo7/Lmo7 |
Background: |
involves: 129S7/SvEvBrd * C57BL/6 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Putilina T |
Year: |
1998 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Analysis of a human cDNA containing a tissue-specific alternatively spliced LIM domain. |
Volume: |
252 |
Issue: |
2 |
Pages: |
433-9 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
LIM domain only protein 7 (LMO-7) contains a LIM zinc-binding domain and a PDZ domain. LMO7 is involved in the regulation of cell adhesion and signaling [, , ]. In humans it has several isoforms; isoform 2 and isoform 4 are predominantly expressed in brain []. It may have roles in embryonic development and cancer progression [, , ]. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
422
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
471
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
te Velthuis AJ |
Year: |
2007 |
Journal: |
ScientificWorldJournal |
Title: |
PDZ and LIM domain-encoding genes: molecular interactions and their role in development. |
Volume: |
7 |
|
Pages: |
1470-92 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1453
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
188
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1189
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1604
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1625
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1699
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1699
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
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•
•
•
•
•
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