Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:1367018 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1756923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826053 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_003427_04 |
|
Specimen Label: |
euxassay_003427_04 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1367018 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1756923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826053 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_003427_05 |
|
Specimen Label: |
euxassay_003427_05 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1367018 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1756923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826053 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_003427_06 |
|
Specimen Label: |
euxassay_003427_06 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1367018 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1756923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826053 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_003427_07 |
|
Specimen Label: |
euxassay_003427_07 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1367018 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1756923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826053 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_003427_20 |
|
Specimen Label: |
euxassay_003427_20 |
Detected: |
true |
Specimen Num: |
17 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1367018 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1756923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826053 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_003427_21 |
|
Specimen Label: |
euxassay_003427_21 |
Detected: |
true |
Specimen Num: |
18 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1367018 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1756923 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826053 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_003427_22 |
|
Specimen Label: |
euxassay_003427_22 |
Detected: |
true |
Specimen Num: |
19 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1367018 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826053 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_003427_07 |
|
Specimen Label: |
euxassay_003427_07 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1367018 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826053 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_003427_08 |
|
Specimen Label: |
euxassay_003427_08 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1367018 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826053 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_003427_19 |
|
Specimen Label: |
euxassay_003427_19 |
Detected: |
true |
Specimen Num: |
16 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1367018 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679523 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826053 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_003427_20 |
|
Specimen Label: |
euxassay_003427_20 |
Detected: |
true |
Specimen Num: |
17 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5788860 |
Assay Type: |
RNA in situ |
Annotation Date: |
2016-08-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3102528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5788861 |
Age: |
postnatal week 18 |
Image: |
4C |
|
Specimen Label: |
4C |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1367018 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826053 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_003427_09 |
|
Specimen Label: |
euxassay_003427_09 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1367018 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826053 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_003427_18 |
|
Specimen Label: |
euxassay_003427_18 |
Detected: |
true |
Specimen Num: |
15 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5788781 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2016-08-16 |
Strength: |
Weak |
Sex: |
Male |
Emaps: |
EMAPS:3148828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5788863 |
Age: |
postnatal day 56 |
Image: |
2D |
|
Specimen Label: |
2D |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5788781 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2016-08-16 |
Strength: |
Weak |
Sex: |
Male |
Emaps: |
EMAPS:3148828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:5788865 |
Age: |
postnatal day 56 |
Image: |
2D |
|
Specimen Label: |
2D |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
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Li MR |
Year: |
2022 |
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Int J Biol Sci |
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MAD2B promotes podocyte injury through regulating Numb-dependent Notch 1 pathway in diabetic nephropathy. |
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J Biol Chem |
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Nat Commun |
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•
•
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Publication |
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Nature |
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JAX Reproductive Mutagenesis Program |
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MGI Direct Data Submission |
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Heritable mouse mutants from The Jackson Laboratory Reproductive Genomics Mutagenesis Program |
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Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP) |
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Database Release |
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Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration |
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Title: |
LocusLink Collaboration |
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Wellcome Trust Sanger Institute |
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MGI Direct Data Submission |
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Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
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The Gene Ontology Consortium |
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Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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UniProt-GOA |
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Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
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Mouse Genome Informatics Scientific Curators |
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MGI Sequence Curation Reference |
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Mouse Genome Informatics Scientific Curators |
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Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
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Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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Allen Institute for Brain Science |
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•
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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•
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•
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Publication |
First Author: |
Boersma V |
Year: |
2015 |
Journal: |
Nature |
Title: |
MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection. |
Volume: |
521 |
Issue: |
7553 |
Pages: |
537-540 |
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DO Term |
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•
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Publication |
First Author: |
Zhang H |
Year: |
2006 |
Journal: |
Genetics |
Title: |
Saccharomyces cerevisiae polymerase zeta functions in mitochondria. |
Volume: |
172 |
Issue: |
4 |
Pages: |
2683-8 |
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•
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•
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Publication |
First Author: |
Wang X |
Year: |
2019 |
Journal: |
J Biol Chem |
Title: |
REV7 has a dynamic adaptor region to accommodate small GTPase RAN/Shigella IpaB ligands, and its activity is regulated by the RanGTP/GDP switch. |
Volume: |
294 |
Issue: |
43 |
Pages: |
15733-15742 |
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Protein Domain |
Type: |
Family |
Description: |
This entry includes Mad2 and Mad2-like proteins, including Mad2/Rev7 from yeasts and MAD2A/B from animals. Mad2 is a central component of the spindle assembly checkpoint, which is a feedback control that prevents cells with incompletely assembled spindles from leaving mitosis [, ]. Rev7 (also known as MAD2L2 or MAD2B) is an accessory subunit of DNA polymerase zeta []. It also acts as an interaction module in a broad array of cellular pathways, including translesion DNA synthesis, cell cycle control, and nonhomologous end joining []. |
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Publication |
First Author: |
Li R |
Year: |
1993 |
Journal: |
Nature |
Title: |
The mitotic feedback control gene MAD2 encodes the alpha-subunit of a prenyltransferase. |
Volume: |
366 |
Issue: |
6450 |
Pages: |
82-4 |
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Publication |
First Author: |
Poddar A |
Year: |
2005 |
Journal: |
Eukaryot Cell |
Title: |
Two complexes of spindle checkpoint proteins containing Cdc20 and Mad2 assemble during mitosis independently of the kinetochore in Saccharomyces cerevisiae. |
Volume: |
4 |
Issue: |
5 |
Pages: |
867-78 |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
106
 |
Fragment?: |
true |
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•
•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
205
 |
Fragment?: |
false |
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•
•
•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
211
 |
Fragment?: |
false |
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•
•
•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
173
 |
Fragment?: |
true |
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•
•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
178
 |
Fragment?: |
false |
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•
•
•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
105
 |
Fragment?: |
false |
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•
•
•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
205
 |
Fragment?: |
false |
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•
•
•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
205
 |
Fragment?: |
false |
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•
•
•
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