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Search results 201 to 216 out of 216 for Mapre2

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Type Details Score
Publication
17658256 | J:127422
First Author: Straube A
Year: 2007
Journal: Curr Biol
Title: EB3 regulates microtubule dynamics at the cell cortex and is required for myoblast elongation and fusion.
Volume: 17
Issue: 15
Pages: 1318-25
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Publication
18322465 | -
First Author: Akhmanova A
Year: 2008
Journal: Nat Rev Mol Cell Biol
Title: Tracking the ends: a dynamic protein network controls the fate of microtubule tips.
Volume: 9
Issue: 4
Pages: 309-22
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Publication
20008324 | -
First Author: De Groot CO
Year: 2010
Journal: J Biol Chem
Title: Molecular insights into mammalian end-binding protein heterodimerization.
Volume: 285
Issue: 8
Pages: 5802-14
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Publication
21062375 | -
First Author: Liu H
Year: 2010
Journal: Mol Microbiol
Title: Aspergillus fumigatus AcuM regulates both iron acquisition and gluconeogenesis.
Volume: 78
Issue: 4
Pages: 1038-54
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Publication
18806788 | -
First Author: Geraldo S
Year: 2008
Journal: Nat Cell Biol
Title: Targeting of the F-actin-binding protein drebrin by the microtubule plus-tip protein EB3 is required for neuritogenesis.
Volume: 10
Issue: 10
Pages: 1181-9
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Protein Domain
IPR027328 | MAPRE
Type: Family
Description: This entry represents the microtubule-associated protein RP/EB (MAPRE) family, including MAPRE1 (EB1), MAPRE2 (RP1, also known as EB2), MAPRE3 (EBF3, also known as EB3) and their homologues from eukaryotes. Despite their high protein sequence conservation, the individual EBs exhibit different regulatory and functional properties []. For instance, EB1 and EB3, but not EB2, promote persistent microtubule growth by suppressing catastrophes [].EB1 contains an N-terminal calponin homology (CH) domain that is responsible for the interaction with microtubules (MTs), and a C-terminal coiled coil domain that extends into a four-helix bundle, required for dimer formation []. Through their C-terminal sequences, EBs interact with most other known +TIPs (plus end tracking proteins) and recruit many of them to the growing MT ends [, ]. EB1 is involved in MT anchoring at the centrosome and cell migration []. EB2 is highly expressed in pancreatic cancer cells, and seems to be involved in perineural invasion []. EB3 is specifically upregulated upon myogenic differentiation. Knockdown of EB3, but not that of EB1, prevents myoblast elongation and fusion into myotubes []. This entry also includes bZIP transcription factor hapX from the yeast Neosartorya fumigata, which is a transcription factor required for repression of genes during iron starvation [].
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Protein
Q3TG90
Organism: Mus musculus/domesticus
Length: 171  
Fragment?: false
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Protein
Q8R001
Organism: Mus musculus/domesticus
Length: 326  
Fragment?: false
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Protein
E9Q6X0
Organism: Mus musculus/domesticus
Length: 284  
Fragment?: false
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Protein
D3YYK8
Organism: Mus musculus/domesticus
Length: 260  
Fragment?: true
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Protein
A0A0J9YVB9
Organism: Mus musculus/domesticus
Length: 140  
Fragment?: true
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Protein
Q61166
Organism: Mus musculus/domesticus
Length: 268  
Fragment?: false
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Protein
Q6PER3
Organism: Mus musculus/domesticus
Length: 281  
Fragment?: false
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Protein
Q3U4H0
Organism: Mus musculus/domesticus
Length: 268  
Fragment?: false
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Protein
Q2UZW7
Organism: Mus musculus/domesticus
Length: 281  
Fragment?: false
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Protein
D3Z6G3
Organism: Mus musculus/domesticus
Length: 266  
Fragment?: false
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