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Search results 201 to 300 out of 2672 for Mapt

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Type Details Score
Publication
31673052 | J:284884
First Author: Metaxas A
Year: 2019
Journal: Sci Rep
Title: Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer's disease.
Volume: 9
Issue: 1
Pages: 15758
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Publication
24849348 | J:211349
First Author: Ma QL
Year: 2014
Journal: J Neurosci
Title: Loss of MAP function leads to hippocampal synapse loss and deficits in the Morris Water Maze with aging.
Volume: 34
Issue: 21
Pages: 7124-36
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Publication
10973990 | J:77655
First Author: Takei Y
Year: 2000
Journal: J Cell Biol
Title: Defects in axonal elongation and neuronal migration in mice with disrupted tau and map1b genes.
Volume: 150
Issue: 5
Pages: 989-1000
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Publication
25326800 | J:227814
First Author: Zhang Z
Year: 2014
Journal: Nat Med
Title: Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease.
Volume: 20
Issue: 11
Pages: 1254-62
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Publication
23425014 | J:218147
First Author: Caccamo A
Year: 2013
Journal: Aging Cell
Title: mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies.
Volume: 12
Issue: 3
Pages: 370-80
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Publication
26089772 | J:288934
 
First Author: Maphis N
Year: 2015
Journal: Front Neurosci
Title: Loss of tau rescues inflammation-mediated neurodegeneration.
Volume: 9
Pages: 196
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Publication
20409077 | J:221852
First Author: Pehar M
Year: 2010
Journal: Aging Cell
Title: Altered longevity-assurance activity of p53:p44 in the mouse causes memory loss, neurodegeneration and premature death.
Volume: 9
Issue: 2
Pages: 174-90
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Allele
Tc(HSA17*)1Mdk | MGI:6729680
Name: transchromosomal, human 17, line 1, Michael Koob; transchromosomal, human 17, line 1, Michael D Koob
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Publication
29859869 | J:270253
 
First Author: Das M
Year: 2018
Journal: Neurobiol Dis
Title: Neuronal levels and sequence of tau modulate the power of brain rhythms.
Volume: 117
Pages: 181-188
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Publication
29608591 | J:261369
First Author: Croft CL
Year: 2018
Journal: PLoS One
Title: Novel monoclonal antibodies targeting the microtubule-binding domain of human tau.
Volume: 13
Issue: 4
Pages: e0195211
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Publication
10595944 | J:100972
First Author: Spittaels K
Year: 1999
Journal: Am J Pathol
Title: Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein.
Volume: 155
Issue: 6
Pages: 2153-65
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Publication
15509565 | J:96869
First Author: Terwel D
Year: 2005
Journal: J Biol Chem
Title: Changed conformation of mutant Tau-P301L underlies the moribund tauopathy, absent in progressive, nonlethal axonopathy of Tau-4R/2N transgenic mice.
Volume: 280
Issue: 5
Pages: 3963-73
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Publication
24498342 | J:212846
First Author: Maurin H
Year: 2014
Journal: PLoS One
Title: Early structural and functional defects in synapses and myelinated axons in stratum lacunosum moleculare in two preclinical models for tauopathy.
Volume: 9
Issue: 2
Pages: e87605
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Publication
32544086 | J:299500
First Author: Gratuze M
Year: 2020
Journal: J Clin Invest
Title: Impact of TREM2R47H variant on tau pathology-induced gliosis and neurodegeneration.
Volume: 130
Issue: 9
Pages: 4954-4968
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Publication
23418567 | J:197198
First Author: Garringer HJ
Year: 2013
Journal: PLoS One
Title: Increased tau phosphorylation and tau truncation, and decreased synaptophysin levels in mutant BRI2/tau transgenic mice.
Volume: 8
Issue: 2
Pages: e56426
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Publication
15069197 | J:89593
First Author: Luikenhuis S
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Expression of MeCP2 in postmitotic neurons rescues Rett syndrome in mice.
Volume: 101
Issue: 16
Pages: 6033-8
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Publication
22464332 | J:186082
First Author: Nakamura K
Year: 2012
Journal: Cell
Title: Proline isomer-specific antibodies reveal the early pathogenic tau conformation in Alzheimer's disease.
Volume: 149
Issue: 1
Pages: 232-44
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Publication
18431510 | J:135144
First Author: Lim J
Year: 2008
Journal: J Clin Invest
Title: Pin1 has opposite effects on wild-type and P301L tau stability and tauopathy.
Volume: 118
Issue: 5
Pages: 1877-89
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Publication
18346797 | J:133213
First Author: Navarro P
Year: 2008
Journal: Behav Brain Res
Title: Memory and exploratory impairment in mice that lack the Park-2 gene and that over-express the human FTDP-17 mutant Tau.
Volume: 189
Issue: 2
Pages: 350-6
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Publication
33139698 | J:297772
First Author: Trzeciakiewicz H
Year: 2020
Journal: Nat Commun
Title: An HDAC6-dependent surveillance mechanism suppresses tau-mediated neurodegeneration and cognitive decline.
Volume: 11
Issue: 1
Pages: 5522
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Publication
30455179 | J:267832
 
First Author: McInturff S
Year: 2018
Journal: Biol Open
Title: Characterization of spatial and temporal development of Type I and Type II hair cells in the mouse utricle using new cell-type-specific markers.
Volume: 7
Issue: 11
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Publication
19233709 | J:153374
First Author: Shen Q
Year: 2009
Journal: Parkinsonism Relat Disord
Title: Expression QTL and regulatory network analysis of microtubule-associated protein tau gene.
Volume: 15
Issue: 7
Pages: 525-31
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Publication
27373369 | J:240784
 
First Author: Li T
Year: 2016
Journal: Nat Commun
Title: The neuritic plaque facilitates pathological conversion of tau in an Alzheimer's disease mouse model.
Volume: 7
Pages: 12082
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Publication
31235644 | J:283607
First Author: Kubo A
Year: 2019
Journal: J Neurosci
Title: Ectopic Expression Induces Abnormal Somatodendritic Distribution of Tau in the Mouse Brain.
Volume: 39
Issue: 34
Pages: 6781-6797
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Publication
34065232 | J:339739
 
First Author: Lidón L
Year: 2021
Journal: Int J Mol Sci
Title: Tau Exon 10 Inclusion by PrP(C) through Downregulating GSK3β Activity.
Volume: 22
Issue: 10
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Publication
25558816 | J:234457
First Author: Xia D
Year: 2015
Journal: Biochim Biophys Acta
Title: Pseudophosphorylation of Tau at distinct epitopes or the presence of the P301L mutation targets the microtubule-associated protein Tau to dendritic spines.
Volume: 1852
Issue: 5
Pages: 913-24
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Publication
21430171 | J:170310
First Author: Maeda J
Year: 2011
Journal: J Neurosci
Title: In vivo positron emission tomographic imaging of glial responses to amyloid-beta and tau pathologies in mouse models of Alzheimer's disease and related disorders.
Volume: 31
Issue: 12
Pages: 4720-30
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Publication
19897719 | J:154750
First Author: Rhein V
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice.
Volume: 106
Issue: 47
Pages: 20057-62
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Publication
31263146 | J:285997
First Author: Crotti A
Year: 2019
Journal: Sci Rep
Title: BIN1 favors the spreading of Tau via extracellular vesicles.
Volume: 9
Issue: 1
Pages: 9477
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Publication
11007782 | J:100971
First Author: Spittaels K
Year: 2000
Journal: J Biol Chem
Title: Glycogen synthase kinase-3beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice.
Volume: 275
Issue: 52
Pages: 41340-9
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Publication
34001284 | J:351242
First Author: Galán-Ganga M
Year: 2021
Journal: Acta Neuropathol Commun
Title: Cannabinoid receptor CB2 ablation protects against TAU induced neurodegeneration.
Volume: 9
Issue: 1
Pages: 90
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Publication
34516970 | J:334154
 
First Author: Di Lauro C
Year: 2022
Journal: Prog Neurobiol
Title: P2X7 receptor blockade reduces tau induced toxicity, therapeutic implications in tauopathies.
Volume: 208
Pages: 102173
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Publication
12165467 | J:78400
First Author: Higuchi M
Year: 2002
Journal: Neuron
Title: Transgenic mouse model of tauopathies with glial pathology and nervous system degeneration.
Volume: 35
Issue: 3
Pages: 433-46
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Publication
24586484 | J:213437
First Author: Storbeck M
Year: 2014
Journal: PLoS One
Title: Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain.
Volume: 9
Issue: 2
Pages: e89020
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Publication
31586516 | J:284540
First Author: Paixão S
Year: 2019
Journal: Neuron
Title: Identification of Spinal Neurons Contributing to the Dorsal Column Projection Mediating Fine Touch and Corrective Motor Movements.
Volume: 104
Issue: 4
Pages: 749-764.e6
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Publication
28959956 | J:256914
First Author: Shi Y
Year: 2017
Journal: Nature
Title: ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.
Volume: 549
Issue: 7673
Pages: 523-527
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Publication
20655099 | J:164597
First Author: Ittner LM
Year: 2010
Journal: Cell
Title: Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models.
Volume: 142
Issue: 3
Pages: 387-97
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Publication
25635458 | J:219791
First Author: Bourane S
Year: 2015
Journal: Cell
Title: Identification of a spinal circuit for light touch and fine motor control.
Volume: 160
Issue: 3
Pages: 503-15
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Publication
37499037 | J:339456
First Author: Zhang ZY
Year: 2023
Journal: Science
Title: TRIM11 protects against tauopathies and is down-regulated in Alzheimer's disease.
Volume: 381
Issue: 6656
Pages: eadd6696
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Publication
27189884 | J:235964
 
First Author: Michalski D
Year: 2016
Journal: Neuroscience
Title: Decline of microtubule-associated protein tau after experimental stroke in differently aged wild-type and 3xTg mice with Alzheimer-like alterations.
Volume: 330
Pages: 1-11
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Publication
29632073 | J:264136
First Author: Mondragón-Rodríguez S
Year: 2018
Journal: J Biol Chem
Title: Phosphorylation of Tau protein correlates with changes in hippocampal theta oscillations and reduces hippocampal excitability in Alzheimer's model.
Volume: 293
Issue: 22
Pages: 8462-8472
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Publication
34437570 | J:311297
First Author: Lee SH
Year: 2021
Journal: PLoS One
Title: Three month inhalation exposure to low-level PM2.5 induced brain toxicity in an Alzheimer's disease mouse model.
Volume: 16
Issue: 8
Pages: e0254587
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Publication
30734228 | J:358330
First Author: Li L
Year: 2019
Journal: Mol Neurobiol
Title: Pathological Alterations of Tau in Alzheimer's Disease and 3xTg-AD Mouse Brains.
Volume: 56
Issue: 9
Pages: 6168-6183
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Publication
24176788 | J:207203
 
First Author: Baglietto-Vargas D
Year: 2014
Journal: Neurobiol Dis
Title: Endogenous murine tau promotes neurofibrillary tangles in 3xTg-AD mice without affecting cognition.
Volume: 62
Pages: 407-15
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Publication
16282321 | J:107286
First Author: Oddo S
Year: 2006
Journal: J Biol Chem
Title: Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. A link between Abeta and tau pathology.
Volume: 281
Issue: 3
Pages: 1599-604
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Publication
32585593 | J:311347
First Author: Wander CM
Year: 2020
Journal: iScience
Title: The Accumulation of Tau-Immunoreactive Hippocampal Granules and Corpora Amylacea Implicates Reactive Glia in Tau Pathogenesis during Aging.
Volume: 23
Issue: 7
Pages: 101255
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Publication
30108137 | J:265995
First Author: Martini-Stoica H
Year: 2018
Journal: J Exp Med
Title: TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreading.
Volume: 215
Issue: 9
Pages: 2355-2377
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Publication
38575590 | J:359258
First Author: Gautam M
Year: 2024
Journal: Nat Commun
Title: Distinct local and global functions of mouse Aβ low-threshold mechanoreceptors in mechanical nociception.
Volume: 15
Issue: 1
Pages: 2911
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Publication
36368315 | J:336013
First Author: Gratuze M
Year: 2023
Journal: Neuron
Title: TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4.
Volume: 111
Issue: 2
Pages: 202-219.e7
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Publication
31433986 | J:280229
First Author: Wu T
Year: 2019
Journal: Cell Rep
Title: Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy.
Volume: 28
Issue: 8
Pages: 2111-2123.e6
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Publication
35413950 | J:355365
First Author: Wang C
Year: 2022
Journal: Nat Commun
Title: Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy.
Volume: 13
Issue: 1
Pages: 1969
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Publication
34646018 | J:344014
First Author: Liu S
Year: 2021
Journal: Nature
Title: A neuroanatomical basis for electroacupuncture to drive the vagal-adrenal axis.
Volume: 598
Issue: 7882
Pages: 641-645
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Publication
34185417 | J:351257
First Author: Wu D
Year: 2021
Journal: Clin Transl Med
Title: Medial septum tau accumulation induces spatial memory deficit via disrupting medial septum-hippocampus cholinergic pathway.
Volume: 11
Issue: 6
Pages: e428
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Publication
21368062 | J:170670
First Author: Romberg C
Year: 2011
Journal: J Neurosci
Title: Impaired attention in the 3xTgAD mouse model of Alzheimer's disease: rescue by donepezil (Aricept).
Volume: 31
Issue: 9
Pages: 3500-7
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Publication
31600350 | J:280806
First Author: Joseph DJ
Year: 2019
Journal: PLoS One
Title: Isoflurane mediated neuropathological and cognitive impairments in the triple transgenic Alzheimer's mouse model are associated with hippocampal synaptic deficits in an age-dependent manner.
Volume: 14
Issue: 10
Pages: e0223509
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Publication
21103384 | J:166981
First Author: Bittner T
Year: 2010
Journal: PLoS One
Title: Multiple events lead to dendritic spine loss in triple transgenic Alzheimer's disease mice.
Volume: 5
Issue: 11
Pages: e15477
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Publication
37095396 | J:344021
First Author: Udeochu JC
Year: 2023
Journal: Nat Neurosci
Title: Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience.
Volume: 26
Issue: 5
Pages: 737-750
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Publication
27779468 | J:238738
   
First Author: Rousseaux MW
Year: 2016
Journal: Elife
Title: TRIM28 regulates the nuclear accumulation and toxicity of both alpha-synuclein and tau.
Volume: 5
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Publication
29175324 | J:270559
First Author: Cai HY
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Lixisenatide reduces amyloid plaques, neurofibrillary tangles and neuroinflammation in an APP/PS1/tau mouse model of Alzheimer's disease.
Volume: 495
Issue: 1
Pages: 1034-1040
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Publication
33431651 | J:301526
 
First Author: Giovinazzo D
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Hydrogen sulfide is neuroprotective in Alzheimer's disease by sulfhydrating GSK3β and inhibiting Tau hyperphosphorylation.
Volume: 118
Issue: 4
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Publication
36952340 | J:351410
First Author: Huo J
Year: 2023
Journal: Cell Rep
Title: Identification of brain-to-spinal circuits controlling the laterality and duration of mechanical allodynia in mice.
Volume: 42
Issue: 4
Pages: 112300
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Publication
32791039 | J:341758
First Author: Liu S
Year: 2020
Journal: Neuron
Title: Somatotopic Organization and Intensity Dependence in Driving Distinct NPY-Expressing Sympathetic Pathways by Electroacupuncture.
Volume: 108
Issue: 3
Pages: 436-450.e7
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Publication
37071198 | J:351756
First Author: Chen J
Year: 2023
Journal: Cell Mol Life Sci
Title: APP mediates tau uptake and its overexpression leads to the exacerbated tau pathology.
Volume: 80
Issue: 5
Pages: 123
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Publication
18486110 | J:138344
 
First Author: Hirata-Fukae C
Year: 2008
Journal: Brain Res
Title: Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model.
Volume: 1216
Pages: 92-103
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Publication
27041503 | J:230252
First Author: Tracy TE
Year: 2016
Journal: Neuron
Title: Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss.
Volume: 90
Issue: 2
Pages: 245-60
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Publication
33314529 | J:331908
First Author: Audrain M
Year: 2021
Journal: Alzheimers Dement
Title: Reactive or transgenic increase in microglial TYROBP reveals a TREM2-independent TYROBP-APOE link in wild-type and Alzheimer's-related mice.
Volume: 17
Issue: 2
Pages: 149-163
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Publication
22870188 | J:189666
First Author: Castello NA
Year: 2012
Journal: PLoS One
Title: Genetic knockdown of brain-derived neurotrophic factor in 3xTg-AD mice does not alter Aβ or tau pathology.
Volume: 7
Issue: 8
Pages: e39566
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Publication
28779511 | J:248482
First Author: Branca C
Year: 2017
Journal: Aging Cell
Title: Dyrk1 inhibition improves Alzheimer's disease-like pathology.
Volume: 16
Issue: 5
Pages: 1146-1154
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Protein Coding Gene
MGP_CAROLIEiJ_G0017291 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0019274 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0019242 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0019211 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0019216 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0019025 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_97180 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0019666 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0018579 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0018994 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0019106 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0019097 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0019175 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0019127 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0019703 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0018343 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0018628 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018421 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0018134 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
1374898 | J:1166
First Author: Couchie D
Year: 1992
Journal: Proc Natl Acad Sci U S A
Title: Primary structure of high molecular weight tau present in the peripheral nervous system.
Volume: 89
Issue: 10
Pages: 4378-81
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Publication
3122323 | J:27179
First Author: Lee G
Year: 1988
Journal: Science
Title: The primary structure and heterogeneity of tau protein from mouse brain.
Volume: 239
Issue: 4837
Pages: 285-8
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Publication
7877441 | J:21223
First Author: Sawa A
Year: 1994
Journal: Brain Res Mol Brain Res
Title: Molecular diversity at the carboxyl terminus of human and rat tau.
Volume: 27
Issue: 1
Pages: 111-7
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Publication
18382274 | J:136624
First Author: Hashimoto Y
Year: 2008
Journal: Neuroreport
Title: Neuron-specific and inducible recombination by Cre recombinase in the mouse.
Volume: 19
Issue: 6
Pages: 621-4
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Publication
15493019 | J:94203
First Author: Korets-Smith E
Year: 2004
Journal: Genesis
Title: Cre recombinase specificity defined by the tau locus.
Volume: 40
Issue: 3
Pages: 131-8
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Publication
35474959 | J:306016
First Author: Hirata T
Year: 2021
Journal: Cell Rep Methods
Title: NeuroGT: A brain atlas of neurogenic tagging CreER drivers for birthdate-based classification and manipulation of mouse neurons.
Volume: 1
Issue: 3
Pages: 100012
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Publication
31672846 | J:288786
 
First Author: Hirata T
Year: 2019
Journal: eNeuro
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