Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:1375377 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1779123 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826112 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_004287_11 |
|
Specimen Label: |
euxassay_004287_11 |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1375377 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1779123 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826112 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_004287_12 |
|
Specimen Label: |
euxassay_004287_12 |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1375377 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1779123 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826112 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_004287_13 |
|
Specimen Label: |
euxassay_004287_13 |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1375377 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1779123 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826112 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_004287_14 |
|
Specimen Label: |
euxassay_004287_14 |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1375377 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1779123 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826112 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_004287_15 |
|
Specimen Label: |
euxassay_004287_15 |
Detected: |
true |
Specimen Num: |
15 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1375377 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1779123 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826112 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_004287_16 |
|
Specimen Label: |
euxassay_004287_16 |
Detected: |
true |
Specimen Num: |
16 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1375377 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1779123 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826112 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_004287_17 |
|
Specimen Label: |
euxassay_004287_17 |
Detected: |
true |
Specimen Num: |
17 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1375377 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1779123 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826112 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_004287_18 |
|
Specimen Label: |
euxassay_004287_18 |
Detected: |
true |
Specimen Num: |
18 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1375377 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1779123 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826112 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_004287_19 |
|
Specimen Label: |
euxassay_004287_19 |
Detected: |
true |
Specimen Num: |
19 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1375377 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1779123 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826112 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_004287_20 |
|
Specimen Label: |
euxassay_004287_20 |
Detected: |
true |
Specimen Num: |
20 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1375377 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1779123 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826112 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_004287_21 |
|
Specimen Label: |
euxassay_004287_21 |
Detected: |
true |
Specimen Num: |
21 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1375377 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1779123 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826112 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_004287_22 |
|
Specimen Label: |
euxassay_004287_22 |
Detected: |
true |
Specimen Num: |
22 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5001157 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:1796220 |
|
Stage: |
TS20 |
Assay Id: |
MGI:5541713 |
Age: |
embryonic day 12.5 |
Image: |
GUDMAP:7318 |
|
Specimen Label: |
GUDMAP:7318 |
Detected: |
false |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5001157 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1657717 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:5541713 |
Age: |
embryonic day 10.5 |
Image: |
GUDMAP:7317 |
|
Specimen Label: |
GUDMAP:7317 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Klatt AR |
Year: |
2002 |
Journal: |
Matrix Biol |
Title: |
Expression of matrilins during maturation of mouse skeletal tissues. |
Volume: |
21 |
Issue: |
3 |
Pages: |
289-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Segat D |
Year: |
2000 |
Journal: |
Matrix Biol |
Title: |
Expression of matrilin-1, -2 and -3 in developing mouse limbs and heart. |
Volume: |
19 |
Issue: |
7 |
Pages: |
649-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Paulsson M |
Year: |
1999 |
Journal: |
Biochem Soc Trans |
Title: |
The matrilins: a growing family of A-domain-containing proteins. |
Volume: |
27 |
Issue: |
6 |
Pages: |
824-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li P |
Year: |
2020 |
Journal: |
Int J Mol Sci |
Title: |
Mice Lacking the Matrilin Family of Extracellular Matrix Proteins Develop Mild Skeletal Abnormalities and Are Susceptible to Age-Associated Osteoarthritis. |
Volume: |
21 |
Issue: |
2 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Klatt AR |
Year: |
2001 |
Journal: |
J Biol Chem |
Title: |
Molecular structure, processing, and tissue distribution of matrilin-4. |
Volume: |
276 |
Issue: |
20 |
Pages: |
17267-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Uckelmann H |
Year: |
2016 |
Journal: |
J Exp Med |
Title: |
Extracellular matrix protein Matrilin-4 regulates stress-induced HSC proliferation via CXCR4. |
Volume: |
213 |
Issue: |
10 |
Pages: |
1961-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chakraborty S |
Year: |
2008 |
Journal: |
Physiol Genomics |
Title: |
Shared gene expression profiles in developing heart valves and osteoblast progenitor cells. |
Volume: |
35 |
Issue: |
1 |
Pages: |
75-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
van der Weyden L |
Year: |
2006 |
Journal: |
Am J Pathol |
Title: |
Functional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritis. |
Volume: |
169 |
Issue: |
2 |
Pages: |
515-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kamper M |
Year: |
2017 |
Journal: |
Cell Tissue Res |
Title: |
Absence of collagen IX accelerates hypertrophic differentiation in the embryonic mouse spine through a disturbance of the Ihh-PTHrP feedback loop. |
Volume: |
367 |
Issue: |
2 |
Pages: |
359-367 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ko Y |
Year: |
2004 |
Journal: |
Mol Cell Biol |
Title: |
Matrilin-3 is dispensable for mouse skeletal growth and development. |
Volume: |
24 |
Issue: |
4 |
Pages: |
1691-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mátés L |
Year: |
2004 |
Journal: |
Matrix Biol |
Title: |
Mice lacking the extracellular matrix adaptor protein matrilin-2 develop without obvious abnormalities. |
Volume: |
23 |
Issue: |
3 |
Pages: |
195-204 |
|
•
•
•
•
•
|
Publication |
First Author: |
Naba A |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression. |
Volume: |
7 |
|
Pages: |
40495 |
|
•
•
•
•
•
|
Publication |
First Author: |
Naba A |
Year: |
2012 |
Journal: |
Mol Cell Proteomics |
Title: |
The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices. |
Volume: |
11 |
Issue: |
4 |
Pages: |
M111.014647 |
|
•
•
•
•
•
|
Publication |
First Author: |
Desai J |
Year: |
2006 |
Journal: |
Hum Mol Genet |
Title: |
Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects. |
Volume: |
15 |
Issue: |
8 |
Pages: |
1329-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Abonnenc M |
Year: |
2013 |
Journal: |
Circ Res |
Title: |
Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c. |
Volume: |
113 |
Issue: |
10 |
Pages: |
1138-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
NIH Mouse Knockout Inventory |
Year: |
2004 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the NIH Mouse Knockout Inventory |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2018 |
Journal: |
Database Release |
Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bedogni F |
Year: |
2021 |
Journal: |
Front Mol Neurosci |
Title: |
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
Volume: |
14 |
|
Pages: |
686034 |
|
•
•
•
•
•
|
Publication |
First Author: |
GUDMAP Consortium |
Year: |
2004 |
Journal: |
www.gudmap.org |
Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
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|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
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|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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|
|
•
•
•
•
•
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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•
•
•
•
•
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Piecha D |
Year: |
2002 |
Journal: |
J Invest Dermatol |
Title: |
Expression of matrilin-2 in human skin. |
Volume: |
119 |
Issue: |
1 |
Pages: |
38-43 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Matrilin family consists of four non-collagenous extracellular matrix (ECM) proteins []. Matrilin-1 and matrilin-3 are expressed mainly in cartilage, while matrilin-2 and matrilin-4 are widely distributed in many connective tissues []. Typical matrilin has the similar domain structure with two von Willebrand factor A-like (VWA) domains interconnected by a variable number of epidermal growth factor-like (EGF) domains. The subunits form trimers or tetramers via a C-terminal α-helical coiled-coil domain [].Matrilin-2 (MATN2) is the largest and most complex matrilin. It is made up by two vWFA-like domains connected by ten EGF modules, and has a unique domain located between the second vWFA-like domain and the coiled-coil C-terminal domain []. MATN2 is a structural component of the ECM in many tissues, including the skin [, ]. It participates in peripheral nerve regeneration []and induces proinflammatory responses that could contribute to axonal damage in CNS inflammatory diseases []. It functions as a tumor suppressor in hepatocarcinogenesis []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Deák F |
Year: |
1999 |
Journal: |
Matrix Biol |
Title: |
The matrilins: a novel family of oligomeric extracellular matrix proteins. |
Volume: |
18 |
Issue: |
1 |
Pages: |
55-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Klatt AR |
Year: |
2011 |
Journal: |
Int J Biochem Cell Biol |
Title: |
The matrilins: modulators of extracellular matrix assembly. |
Volume: |
43 |
Issue: |
3 |
Pages: |
320-30 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
280
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
280
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
956
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
937
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
810
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
810
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
957
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
928
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
|
•
•
•
•
•
|