Type |
Details |
Score |
Publication |
First Author: |
Takei Y |
Year: |
2001 |
Journal: |
EMBO Rep |
Title: |
MCM3AP, a novel acetyltransferase that acetylates replication protein MCM3. |
Volume: |
2 |
Issue: |
2 |
Pages: |
119-23 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This entry represents the RNA recognition motif (RRM) of MCM3-associated protein (MCM3AP, also known as GANP), a nuclear protein with multiple domains, which have different functions. GANP serves as the scaffold of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export []. GANP can act as an RNA export factor that interacts with activation-induced cytidine deaminase (AID) and shepherds it from the cytoplasm to the nucleus, and toward the IgV region loci in B cells []. GANP contains the Sac3-homology domain, a putative RNA recognition motif, the Nup-homology domain, and the C-terminal histone-acetyltransferase (HAT) domain. Its HAT domain has been shown to regulate minichromosome maintenance protein 3 (MCM3) []. An alternatively spliced variant of GANP mRNA has been reported in humans. A shorter isoform of GANP (likely to encode an 80kDa protein) is associated with MCM3 of the DNA helicase MCM-complex (composed of MCM2-MCM7) and possesses HAT activity []. |
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•
•
•
•
•
|
Publication |
First Author: |
Coverley D |
Year: |
2005 |
Journal: |
J Cell Sci |
Title: |
Ciz1 promotes mammalian DNA replication. |
Volume: |
118 |
Issue: |
Pt 1 |
Pages: |
101-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Homma H |
Year: |
2021 |
Journal: |
Life Sci Alliance |
Title: |
DNA damage in embryonic neural stem cell determines FTLDs' fate via early-stage neuronal necrosis. |
Volume: |
4 |
Issue: |
7 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Chuang CH |
Year: |
2012 |
Journal: |
Nucleic Acids Res |
Title: |
Post-transcriptional homeostasis and regulation of MCM2-7 in mammalian cells. |
Volume: |
40 |
Issue: |
11 |
Pages: |
4914-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Natale DA |
Year: |
2000 |
Journal: |
EMBO J |
Title: |
Selective instability of Orc1 protein accounts for the absence of functional origin recognition complexes during the M-G(1) transition in mammals. |
Volume: |
19 |
Issue: |
11 |
Pages: |
2728-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
EL-Gazzar MA |
Year: |
2001 |
Journal: |
J Biol Chem |
Title: |
PU.1 is involved in the regulation of B lineage-associated and developmental stage-dependent expression of the germinal center-associated DNA primase GANP. |
Volume: |
276 |
Issue: |
51 |
Pages: |
48000-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guo L |
Year: |
2012 |
Journal: |
Cell Death Differ |
Title: |
Histone demethylase Kdm4b functions as a co-factor of C/EBPβ to promote mitotic clonal expansion during differentiation of 3T3-L1 preadipocytes. |
Volume: |
19 |
Issue: |
12 |
Pages: |
1917-27 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
496
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1971
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1732
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1992
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Jani D |
Year: |
2012 |
Journal: |
Nucleic Acids Res |
Title: |
Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export. |
Volume: |
40 |
Issue: |
10 |
Pages: |
4562-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sweet SM |
Year: |
2009 |
Journal: |
Mol Cell Proteomics |
Title: |
Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry. |
Volume: |
8 |
Issue: |
5 |
Pages: |
904-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Park J |
Year: |
2013 |
Journal: |
Mol Cell |
Title: |
SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. |
Volume: |
50 |
Issue: |
6 |
Pages: |
919-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Villén J |
Year: |
2007 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Large-scale phosphorylation analysis of mouse liver. |
Volume: |
104 |
Issue: |
5 |
Pages: |
1488-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2000 |
Journal: |
Genome Res |
Title: |
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. |
Volume: |
10 |
Issue: |
10 |
Pages: |
1617-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
1999 |
Journal: |
Methods Enzymol |
Title: |
High-efficiency full-length cDNA cloning. |
Volume: |
303 |
|
Pages: |
19-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shibata K |
Year: |
2000 |
Journal: |
Genome Res |
Title: |
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. |
Volume: |
10 |
Issue: |
11 |
Pages: |
1757-71 |
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•
•
•
•
•
|
Publication |
First Author: |
Katayama S |
Year: |
2005 |
Journal: |
Science |
Title: |
Antisense transcription in the mammalian transcriptome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1564-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huttlin EL |
Year: |
2010 |
Journal: |
Cell |
Title: |
A tissue-specific atlas of mouse protein phosphorylation and expression. |
Volume: |
143 |
Issue: |
7 |
Pages: |
1174-89 |
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•
•
•
•
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