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Search results 201 to 239 out of 239 for Mdm4

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Type Details Score
Interaction Experiment
Giglio S (2010)
Description: Regulation of MDM4 (MDMX) function by p76(MDM2): a new facet in the control of p53 activity.
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Interaction Experiment
Pant V (2011)
Description: Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability.
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Allele
Mdm4<tm1Smoc> | MGI:7291015
Name: transformed mouse 3T3 cell double minute 4; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Not Specified
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Strain
MGI:6354395 | B6.129-Mdm4<tm1Smoc>/Smoc
Attribute String: congenic, mutant strain, targeted mutation
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Protein
Q9D067
Organism: Mus musculus/domesticus
Length: 708  
Fragment?: false
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Protein
Q9D067-4
Organism: Mus musculus/domesticus
Length: 663  
Fragment?: false
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Protein
Q9D067-2
Organism: Mus musculus/domesticus
Length: 689  
Fragment?: false
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Protein
Q9D067-3
Organism: Mus musculus/domesticus
Length: 222  
Fragment?: false
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Publication
31547268 | J:286145
 
First Author: LucĂ  R
Year: 2019
Journal: Cancers (Basel)
Title: Estrogens Counteract Platinum-Chemosensitivity by Modifying the Subcellular Localization of MDM4.
Volume: 11
Issue: 9
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Allele
Tg(Actb-Mdm4,-lacZ)1Glo | MGI:5604360
Name: transgene insertion 1, Guillermina Lozano
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
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Allele
Tg(Actb-Mdm4)6Glo | MGI:5604361
Name: transgene insertion 6, Guillermina Lozano
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Actb-Mdm4)15Glo | MGI:5604362
Name: transgene insertion 15, Guillermina Lozano
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
35588102 | J:325001
First Author: Chinnam M
Year: 2022
Journal: PLoS Genet
Title: MDM2 E3 ligase activity is essential for p53 regulation and cell cycle integrity.
Volume: 18
Issue: 5
Pages: e1010171
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Allele
Tg(Actb-EGFP,-Mdm4,-lacZ)1Glo | MGI:5604359
Name: transgene insertion 1, Guillermina Lozano
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
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Allele
Mdm4<m1Btlr> | MGI:6200383
Name: transformed mouse 3T3 cell double minute 4; mutation 1, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:6200384 | C57BL/6J-Mdm4<m1Btlr>
Attribute String: mutant strain, chemically induced mutation, coisogenic
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Allele
Mdm4<m2Btlr> | MGI:6285944
Name: transformed mouse 3T3 cell double minute 4; mutation 2, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:6285945 | C57BL/6J-Mdm4<m2Btlr>
Attribute String: mutant strain, coisogenic, chemically induced mutation
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Genotype
Genotype
Symbol: Mdm4/Mdm4
Background: C57BL/6J-Mdm4
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mdm4/Mdm4
Background: C57BL/6J-Mdm4
Zygosity: hm
Has Mutant Allele: true
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HT Experiment
GSE180546 | Snrpb, the gene mutated in CCMS, is haploinsufficient and required for proper splicing and morphogenesis
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
29262616 | J:272648
First Author: Aryal NK
Year: 2017
Journal: Oncotarget
Title: Loss of digestive organ expansion factor (Diexf) reveals an essential role during murine embryonic development that is independent of p53.
Volume: 8
Issue: 61
Pages: 103996-104006
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Publication
33157015 | J:300126
First Author: Bieging-Rolett KT
Year: 2020
Journal: Mol Cell
Title: Zmat3 Is a Key Splicing Regulator in the p53 Tumor Suppression Program.
Volume: 80
Issue: 3
Pages: 452-469.e9
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Publication
27499244 | J:241266
 
First Author: Riascos-Bernal DF
Year: 2016
Journal: Nat Commun
Title: β-Catenin C-terminal signals suppress p53 and are essential for artery formation.
Volume: 7
Pages: 12389
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Publication
32300648 | J:288784
First Author: Toufektchan E
Year: 2020
Journal: Sci Adv
Title: Germline mutation of MDM4, a major p53 regulator, in a familial syndrome of defective telomere maintenance.
Volume: 6
Issue: 15
Pages: eaay3511
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Publication
28472656 | J:256029
First Author: Aldiri I
Year: 2017
Journal: Neuron
Title: The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis.
Volume: 94
Issue: 3
Pages: 550-568.e10
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Publication
29899063 | J:263926
First Author: Bellutti F
Year: 2018
Journal: Cancer Discov
Title: CDK6 Antagonizes p53-Induced Responses during Tumorigenesis.
Volume: 8
Issue: 7
Pages: 884-897
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Publication
21350561 | J:203102
First Author: Kon N
Year: 2011
Journal: Cell Death Differ
Title: Roles of HAUSP-mediated p53 regulation in central nervous system development.
Volume: 18
Issue: 8
Pages: 1366-75
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Publication
39308865 | J:357822
 
First Author: Bertazzon M
Year: 2024
Journal: Front Immunol
Title: The nuclear GYF protein CD2BP2/U5-52K is required for T cell homeostasis.
Volume: 15
Pages: 1415839
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Publication
18451149 | J:134777
First Author: Maguire M
Year: 2008
Journal: Cancer Res
Title: MDM2 regulates dihydrofolate reductase activity through monoubiquitination.
Volume: 68
Issue: 9
Pages: 3232-42
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Publication
38113691 | J:344328
 
First Author: Luo X
Year: 2024
Journal: Int Immunopharmacol
Title: SRSF10 facilitates HCC growth and metastasis by suppressing CD8(+)T cell infiltration and targeting SRSF10 enhances anti-PD-L1 therapy.
Volume: 127
Pages: 111376
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Publication
21840489 | J:176061
First Author: McEvoy J
Year: 2011
Journal: Cancer Cell
Title: Coexpression of normally incompatible developmental pathways in retinoblastoma genesis.
Volume: 20
Issue: 2
Pages: 260-75
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Publication
28265066 | J:298026
First Author: Chapeau EA
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Resistance mechanisms to TP53-MDM2 inhibition identified by in vivo piggyBac transposon mutagenesis screen in an Arf-/- mouse model.
Volume: 114
Issue: 12
Pages: 3151-3156
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Publication
11042159 | J:68323
First Author: Carninci P
Year: 2000
Journal: Genome Res
Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Volume: 10
Issue: 10
Pages: 1617-30
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Publication
10349636 | J:80645
 
First Author: Carninci P
Year: 1999
Journal: Methods Enzymol
Title: High-efficiency full-length cDNA cloning.
Volume: 303
Pages: 19-44
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Publication
11076861 | J:68324
First Author: Shibata K
Year: 2000
Journal: Genome Res
Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Volume: 10
Issue: 11
Pages: 1757-71
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Publication
16141073 | -
First Author: Katayama S
Year: 2005
Journal: Science
Title: Antisense transcription in the mammalian transcriptome.
Volume: 309
Issue: 5740
Pages: 1564-6
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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