| Type |
Details |
Score |
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
WT vs. Mutant |
| Source: |
GEO |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nelson DW |
| Year: |
2011 |
| Journal: |
J Lipid Res |
| Title: |
Deficiency of MGAT2 increases energy expenditure without high-fat feeding and protects genetically obese mice from excessive weight gain. |
| Volume: |
52 |
| Issue: |
9 |
| Pages: |
1723-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okawa M |
| Year: |
2009 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Role of MGAT2 and DGAT1 in the release of gut peptides after triglyceride ingestion. |
| Volume: |
390 |
| Issue: |
3 |
| Pages: |
377-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Asmat MS |
| Year: |
2024 |
| Journal: |
Front Cell Dev Biol |
| Title: |
Deletion of Mgat2 in spermatogonia blocks spermatogenesis. |
| Volume: |
12 |
|
| Pages: |
1428715 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Allele |
| Name: |
mannoside acetylglucosaminyltransferase 2; targeted mutation 1.1, Jamey Marth |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
334
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mgat2/Mgat2 |
| Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Mgat2/Mgat2 |
| Background: |
involves: 129S1/Sv * 129X1/SvJ * ICR |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| DO Term |
|
•
•
•
•
•
|
| Publication |
| First Author: |
D'Agostaro GA |
| Year: |
1995 |
| Journal: |
J Biol Chem |
| Title: |
Molecular cloning and expression of cDNA encoding the rat UDP-N-acetylglucosamine:alpha-6-D-mannoside beta-1,2-N-acetylglucosaminyltransferase II. |
| Volume: |
270 |
| Issue: |
25 |
| Pages: |
15211-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Van Geet C |
| Year: |
2001 |
| Journal: |
J Inherit Metab Dis |
| Title: |
Congenital disorders of glycosylation type Ia and IIa are associated with different primary haemostatic complications. |
| Volume: |
24 |
| Issue: |
4 |
| Pages: |
477-92 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
N-acetylglucosaminyltransferase II () is a Golgi resident enzyme that catalyzes an essential step in the biosynthetic pathway leading from high mannose to complex N-linked oligosaccharides []. Mutations in the MGAT2 gene lead to a congenital disorder of glycosylation (CDG IIa). CDG IIa patients have an increased bleeding tendency, unrelated to coagulation factors []. |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
WT vs. Mutant |
| Source: |
GEO |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu C |
| Year: |
2024 |
| Journal: |
Cell Rep |
| Title: |
HuR promotes triglyceride synthesis and intestinal fat absorption. |
| Volume: |
43 |
| Issue: |
5 |
| Pages: |
114238 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
442
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
442
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
442
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
442
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ye Z |
| Year: |
2004 |
| Journal: |
Glycobiology |
| Title: |
N-glycan branching requirement in neuronal and postnatal viability. |
| Volume: |
14 |
| Issue: |
6 |
| Pages: |
547-58 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nelson DW |
| Year: |
2014 |
| Journal: |
J Biol Chem |
| Title: |
Intestine-specific deletion of acyl-CoA:monoacylglycerol acyltransferase (MGAT) 2 protects mice from diet-induced obesity and glucose intolerance. |
| Volume: |
289 |
| Issue: |
25 |
| Pages: |
17338-49 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yen CL |
| Year: |
2009 |
| Journal: |
Nat Med |
| Title: |
Deficiency of the intestinal enzyme acyl CoA:monoacylglycerol acyltransferase-2 protects mice from metabolic disorders induced by high-fat feeding. |
| Volume: |
15 |
| Issue: |
4 |
| Pages: |
442-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Banh T |
| Year: |
2015 |
| Journal: |
J Lipid Res |
| Title: |
Adult-onset deficiency of acyl CoA:monoacylglycerol acyltransferase 2 protects mice from diet-induced obesity and glucose intolerance. |
| Volume: |
56 |
| Issue: |
2 |
| Pages: |
379-89 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gao Y |
| Year: |
2013 |
| Journal: |
J Lipid Res |
| Title: |
Intestine-specific expression of MOGAT2 partially restores metabolic efficiency in Mogat2-deficient mice. |
| Volume: |
54 |
| Issue: |
6 |
| Pages: |
1644-52 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Brandt C |
| Year: |
2016 |
| Journal: |
Biochem J |
| Title: |
Diacylglycerol acyltransferase-2 and monoacylglycerol acyltransferase-2 are ubiquitinated proteins that are degraded by the 26S proteasome. |
| Volume: |
473 |
| Issue: |
20 |
| Pages: |
3621-3637 |
|
•
•
•
•
•
|