Type |
Details |
Score |
Publication |
First Author: |
Liu Y |
Year: |
2010 |
Journal: |
Mol Cell Neurosci |
Title: |
Circulating neprilysin clears brain amyloid. |
Volume: |
45 |
Issue: |
2 |
Pages: |
101-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang W |
Year: |
2019 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Apelin protects against abdominal aortic aneurysm and the therapeutic role of neutral endopeptidase resistant apelin analogs. |
Volume: |
116 |
Issue: |
26 |
Pages: |
13006-13015 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weil M |
Year: |
1995 |
Journal: |
Development |
Title: |
A role for mesenchyme-derived tachykinins in tooth and mammary gland morphogenesis. |
Volume: |
121 |
Issue: |
8 |
Pages: |
2419-28 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gilbert DJ |
Year: |
1999 |
Journal: |
Mamm Genome |
Title: |
The neurobeachin gene (Nbea) identifies a new region of homology between mouse central chromosome 3 and human chromosome 13q13. |
Volume: |
10 |
Issue: |
10 |
Pages: |
1030-1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Eckman EA |
Year: |
2006 |
Journal: |
J Biol Chem |
Title: |
Regulation of steady-state beta-amyloid levels in the brain by neprilysin and endothelin-converting enzyme but not angiotensin-converting enzyme. |
Volume: |
281 |
Issue: |
41 |
Pages: |
30471-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Oishi H |
Year: |
2005 |
Journal: |
Arthritis Rheum |
Title: |
Accelerating effect of an MRL gene locus on the severity and onset of arthropathy in DBA/1 mice. |
Volume: |
52 |
Issue: |
3 |
Pages: |
959-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Domenig O |
Year: |
2016 |
Journal: |
Sci Rep |
Title: |
Neprilysin is a Mediator of Alternative Renin-Angiotensin-System Activation in the Murine and Human Kidney. |
Volume: |
6 |
|
Pages: |
33678 |
|
•
•
•
•
•
|
Publication |
First Author: |
Desbois C |
Year: |
1994 |
Journal: |
Mamm Genome |
Title: |
Localization of the osteocalcin gene cluster on mouse chromosome 3. |
Volume: |
5 |
Issue: |
5 |
Pages: |
321-2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ruchon AF |
Year: |
2000 |
Journal: |
J Bone Miner Res |
Title: |
Developmental expression and tissue distribution of Phex protein: effect of the Hyp mutation and relationship to bone markers. |
Volume: |
15 |
Issue: |
8 |
Pages: |
1440-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pardossi-Piquard R |
Year: |
2005 |
Journal: |
Neuron |
Title: |
Presenilin-dependent transcriptional control of the Abeta-degrading enzyme neprilysin by intracellular domains of betaAPP and APLP. |
Volume: |
46 |
Issue: |
4 |
Pages: |
541-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen Y |
Year: |
2014 |
Journal: |
Biol Reprod |
Title: |
Preimplantation mouse embryo is a target for opioid ligand-receptor signaling. |
Volume: |
91 |
Issue: |
1 |
Pages: |
4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pearton DJ |
Year: |
2014 |
Journal: |
Dev Biol |
Title: |
Elf5 counteracts precocious trophoblast differentiation by maintaining Sox2 and 3 and inhibiting Hand1 expression. |
Volume: |
392 |
Issue: |
2 |
Pages: |
344-57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Watson ML |
Year: |
1992 |
Journal: |
J Exp Med |
Title: |
Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci. |
Volume: |
176 |
Issue: |
6 |
Pages: |
1645-56 |
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•
•
•
•
•
|
Publication |
First Author: |
Fukami S |
Year: |
2002 |
Journal: |
Neurosci Res |
Title: |
Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology. |
Volume: |
43 |
Issue: |
1 |
Pages: |
39-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lo HF |
Year: |
2017 |
Journal: |
J Pathol |
Title: |
Association of dysfunctional synapse defective 1 (SYDE1) with restricted fetal growth - SYDE1 regulates placental cell migration and invasion. |
Volume: |
241 |
Issue: |
3 |
Pages: |
324-336 |
|
•
•
•
•
•
|
Publication |
First Author: |
Firulli BA |
Year: |
2010 |
Journal: |
Dev Dyn |
Title: |
Analysis of a Hand1 hypomorphic allele reveals a critical threshold for embryonic viability. |
Volume: |
239 |
Issue: |
10 |
Pages: |
2748-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Just PA |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
LKB1 and Notch Pathways Interact and Control Biliary Morphogenesis. |
Volume: |
10 |
Issue: |
12 |
Pages: |
e0145400 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weis VG |
Year: |
2016 |
Journal: |
Cell Mol Gastroenterol Hepatol |
Title: |
Loss of MYO5B in mice recapitulates Microvillus Inclusion Disease and reveals an apical trafficking pathway distinct to neonatal duodenum. |
Volume: |
2 |
Issue: |
2 |
Pages: |
131-157 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rattner A |
Year: |
1997 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors. |
Volume: |
94 |
Issue: |
7 |
Pages: |
2859-63 |
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•
•
•
•
•
|
Publication |
First Author: |
Gong Y |
Year: |
2022 |
Journal: |
Cells |
Title: |
Peroxisome Metabolism Contributes to PIEZO2-Mediated Mechanical Allodynia. |
Volume: |
11 |
Issue: |
11 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Szeto IYY |
Year: |
2022 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms. |
Volume: |
119 |
Issue: |
46 |
Pages: |
e2122121119 |
|
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•
•
•
•
|
Publication |
First Author: |
Gregor P |
Year: |
1993 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Chromosomal localization of glutamate receptor genes: relationship to familial amyotrophic lateral sclerosis and other neurological disorders of mice and humans. |
Volume: |
90 |
Issue: |
7 |
Pages: |
3053-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
AydoÄŸdu N |
Year: |
2018 |
Journal: |
Development |
Title: |
TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme. |
Volume: |
145 |
Issue: |
23 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Martinez ME |
Year: |
2021 |
Journal: |
Front Neurosci |
Title: |
The Type 3 Deiodinase Is a Critical Modulator of Thyroid Hormone Sensitivity in the Fetal Brain. |
Volume: |
15 |
|
Pages: |
703730 |
|
•
•
•
•
•
|
Publication |
First Author: |
Khang R |
Year: |
2021 |
Journal: |
Sci Rep |
Title: |
Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation. |
Volume: |
11 |
Issue: |
1 |
Pages: |
22745 |
|
•
•
•
•
•
|
Publication |
First Author: |
Oeschger FM |
Year: |
2012 |
Journal: |
Cereb Cortex |
Title: |
Gene expression analysis of the embryonic subplate. |
Volume: |
22 |
Issue: |
6 |
Pages: |
1343-59 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Mutant Mouse Regional Resource Centers |
Year: |
2004 |
Journal: |
Unpublished |
Title: |
Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC) |
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|
•
•
•
•
•
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Publication |
First Author: |
Miller JA |
Year: |
2013 |
Journal: |
Development |
Title: |
Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. |
Volume: |
140 |
Issue: |
22 |
Pages: |
4633-44 |
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•
•
•
•
•
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Publication |
First Author: |
Freeman TC |
Year: |
1998 |
Journal: |
MGI Direct Data Submission |
Title: |
Expression Mapping of Mouse Genes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
NIH Mouse Knockout Inventory |
Year: |
2004 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the NIH Mouse Knockout Inventory |
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|
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•
•
•
•
•
|
Publication |
First Author: |
Ko MS |
Year: |
2000 |
Journal: |
Development |
Title: |
Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. |
Volume: |
127 |
Issue: |
8 |
Pages: |
1737-49 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2018 |
Journal: |
Database Release |
Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
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•
•
•
•
•
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Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
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•
•
•
•
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Publication |
First Author: |
Bedogni F |
Year: |
2021 |
Journal: |
Front Mol Neurosci |
Title: |
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
Volume: |
14 |
|
Pages: |
686034 |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
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•
•
•
•
•
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Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
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•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
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•
•
•
•
•
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Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
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•
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•
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Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
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•
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•
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Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
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•
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Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
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Title: |
GemPharmatech Website. |
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•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
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•
•
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•
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Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
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Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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•
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Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
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•
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Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
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•
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Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
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•
•
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•
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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•
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
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Title: |
Annotation inferences using phylogenetic trees |
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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•
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•
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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•
•
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•
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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•
•
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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•
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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•
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•
•
|
UniProt Feature |
Begin: |
129 |
Description: |
Cleavage; by MME |
Type: |
site |
End: |
130 |
|
•
•
•
•
•
|
Allele |
Name: |
membrane metallo endopeptidase; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
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Publication |
First Author: |
Jolly AL |
Year: |
2017 |
Journal: |
FASEB J |
Title: |
Corneal surface glycosylation is modulated by IL-1R and Pseudomonas aeruginosa challenge but is insufficient for inhibiting bacterial binding. |
Volume: |
31 |
Issue: |
6 |
Pages: |
2393-2404 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
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•
•
•
•
|
DO Term |
|
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•
•
•
•
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Publication |
First Author: |
Nieto V |
Year: |
2019 |
Journal: |
mBio |
Title: |
Type IV Pili Can Mediate Bacterial Motility within Epithelial Cells. |
Volume: |
10 |
Issue: |
4 |
|
|
•
•
•
•
•
|
Allele |
Name: |
membrane metallo endopeptidase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
473
 |
Fragment?: |
false |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Publication |
First Author: |
Shipley JM |
Year: |
1996 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Metalloelastase is required for macrophage-mediated proteolysis and matrix invasion in mice. |
Volume: |
93 |
Issue: |
9 |
Pages: |
3942-6 |
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•
•
•
•
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Publication |
First Author: |
Coats BR |
Year: |
2017 |
Journal: |
Cell Rep |
Title: |
Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity. |
Volume: |
20 |
Issue: |
13 |
Pages: |
3149-3161 |
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•
•
•
•
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Publication |
First Author: |
Tiwari P |
Year: |
2019 |
Journal: |
J Exp Med |
Title: |
Metabolically activated adipose tissue macrophages link obesity to triple-negative breast cancer. |
Volume: |
216 |
Issue: |
6 |
Pages: |
1345-1358 |
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•
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•
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Publication |
First Author: |
Feng Z |
Year: |
2017 |
Journal: |
Cancer Res |
Title: |
Menin and Daxx Interact to Suppress Neuroendocrine Tumors through Epigenetic Control of the Membrane Metallo-Endopeptidase. |
Volume: |
77 |
Issue: |
2 |
Pages: |
401-411 |
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•
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•
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Publication |
First Author: |
Shapiro SD |
Year: |
1992 |
Journal: |
J Biol Chem |
Title: |
Molecular cloning, chromosomal localization, and bacterial expression of a murine macrophage metalloelastase. |
Volume: |
267 |
Issue: |
7 |
Pages: |
4664-71 |
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Publication |
First Author: |
Kahn JH |
Year: |
2020 |
Journal: |
Endocrinology |
Title: |
SMRT Regulates Metabolic Homeostasis and Adipose Tissue Macrophage Phenotypes in Tandem. |
Volume: |
161 |
Issue: |
10 |
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Publication |
First Author: |
Fautsch MP |
Year: |
1995 |
Journal: |
J Cell Biochem |
Title: |
Differential regulation of p34cdc2 and p33cdk2 by transforming growth factor-beta 1 in murine mammary epithelial cells. |
Volume: |
58 |
Issue: |
4 |
Pages: |
517-26 |
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Publication |
First Author: |
Dong Z |
Year: |
1998 |
Journal: |
J Exp Med |
Title: |
Angiostatin-mediated suppression of cancer metastases by primary neoplasms engineered to produce granulocyte/macrophage colony-stimulating factor. |
Volume: |
188 |
Issue: |
4 |
Pages: |
755-63 |
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Publication |
First Author: |
Noordmans GA |
Year: |
2013 |
Journal: |
J Am Soc Nephrol |
Title: |
Genetic analysis of mesangial matrix expansion in aging mice and identification of Far2 as a candidate gene. |
Volume: |
24 |
Issue: |
12 |
Pages: |
1995-2001 |
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Publication |
First Author: |
Reheman A |
Year: |
2019 |
Journal: |
Sci Rep |
Title: |
Optimization of Extraction Technology of Majun Mupakhi Ela and its Effect on Hydrocortisone-induced Kidney Yang Deficiency in Mice. |
Volume: |
9 |
Issue: |
1 |
Pages: |
4628 |
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Publication |
First Author: |
Churg A |
Year: |
2001 |
Journal: |
Lab Invest |
Title: |
Alpha-1-antitrypsin and a broad spectrum metalloprotease inhibitor, RS113456, have similar acute anti-inflammatory effects. |
Volume: |
81 |
Issue: |
8 |
Pages: |
1119-31 |
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Publication |
First Author: |
Poursharifi P |
Year: |
2023 |
Journal: |
Mol Metab |
Title: |
ABHD6 suppression promotes anti-inflammatory polarization of adipose tissue macrophages via 2-monoacylglycerol/PPAR signaling in obese mice. |
Volume: |
78 |
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Pages: |
101822 |
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Publication |
First Author: |
Madlener M |
Year: |
1998 |
Journal: |
Exp Cell Res |
Title: |
Matrix metalloproteinases (MMPs) and their physiological inhibitors (TIMPs) are differentially expressed during excisional skin wound repair. |
Volume: |
242 |
Issue: |
1 |
Pages: |
201-10 |
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