| Type |
Details |
Score |
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
996
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
938
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1009
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
958
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cornick S |
| Year: |
2019 |
| Journal: |
Nat Commun |
| Title: |
VAMP8-mediated MUC2 mucin exocytosis from colonic goblet cells maintains innate intestinal homeostasis. |
| Volume: |
10 |
| Issue: |
1 |
| Pages: |
4306 |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE9913 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mejías-Luque R |
| Year: |
2010 |
| Journal: |
Oncogene |
| Title: |
Inflammation modulates the expression of the intestinal mucins MUC2 and MUC4 in gastric tumors. |
| Volume: |
29 |
| Issue: |
12 |
| Pages: |
1753-62 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Recktenwald CV |
| Year: |
2024 |
| Journal: |
Cell Rep |
| Title: |
The structure of the second CysD domain of MUC2 and role in mucin organization by transglutaminase-based cross-linking. |
| Volume: |
43 |
| Issue: |
5 |
| Pages: |
114207 |
|
•
•
•
•
•
|
| Allele |
| Name: |
mucin 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Inducible, Recombinase, Reporter |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Thomsson KA |
| Year: |
2012 |
| Journal: |
Glycobiology |
| Title: |
Detailed O-glycomics of the Muc2 mucin from colon of wild-type, core 1- and core 3-transferase-deficient mice highlights differences compared with human MUC2. |
| Volume: |
22 |
| Issue: |
8 |
| Pages: |
1128-39 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| CL Term |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE56577 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
WT vs. Mutant |
| Source: |
GEO |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
WT vs. Mutant |
| Source: |
GEO |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
RNA-Seq |
| Study Type: |
Baseline |
| Source: |
GEO |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sharpen JDA |
| Year: |
2022 |
| Journal: |
Nat Commun |
| Title: |
Transglutaminase 3 crosslinks the secreted gel-forming mucus component Mucin-2 and stabilizes the colonic mucus layer. |
| Volume: |
13 |
| Issue: |
1 |
| Pages: |
45 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bergström JH |
| Year: |
2014 |
| Journal: |
PLoS One |
| Title: |
AGR2, an endoplasmic reticulum protein, is secreted into the gastrointestinal mucus. |
| Volume: |
9 |
| Issue: |
8 |
| Pages: |
e104186 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
An G |
| Year: |
2007 |
| Journal: |
J Exp Med |
| Title: |
Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans. |
| Volume: |
204 |
| Issue: |
6 |
| Pages: |
1417-29 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tamura A |
| Year: |
2022 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Zranb1-mutant mice display abnormal colonic mucus production and exacerbation of DSS-induced colitis. |
| Volume: |
628 |
|
| Pages: |
147-154 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Desseyn JL |
| Year: |
1998 |
| Journal: |
J Mol Evol |
| Title: |
Evolutionary history of the 11p15 human mucin gene family. |
| Volume: |
46 |
| Issue: |
1 |
| Pages: |
102-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yamaguchi K |
| Year: |
2008 |
| Journal: |
Mol Cancer Ther |
| Title: |
Peroxisome proliferator-activated receptor ligand MCC-555 suppresses intestinal polyps in ApcMin/+ mice via extracellular signal-regulated kinase and peroxisome proliferator-activated receptor-dependent pathways. |
| Volume: |
7 |
| Issue: |
9 |
| Pages: |
2779-87 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kuver R |
| Year: |
2006 |
| Journal: |
Am J Physiol Gastrointest Liver Physiol |
| Title: |
Absence of CFTR is associated with pleiotropic effects on mucins in mouse gallbladder epithelial cells. |
| Volume: |
291 |
| Issue: |
6 |
| Pages: |
G1148-54 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pian Y |
| Year: |
2020 |
| Journal: |
J Immunol |
| Title: |
Type 3 Innate Lymphoid Cells Direct Goblet Cell Differentiation via the LT-LTβR Pathway during Listeria Infection. |
| Volume: |
205 |
| Issue: |
3 |
| Pages: |
853-863 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kober OI |
| Year: |
2014 |
| Journal: |
Am J Physiol Gastrointest Liver Physiol |
| Title: |
γδ T-cell-deficient mice show alterations in mucin expression, glycosylation, and goblet cells but maintain an intact mucus layer. |
| Volume: |
306 |
| Issue: |
7 |
| Pages: |
G582-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stedman A |
| Year: |
2015 |
| Journal: |
Cell Death Differ |
| Title: |
Ribosome biogenesis dysfunction leads to p53-mediated apoptosis and goblet cell differentiation of mouse intestinal stem/progenitor cells. |
| Volume: |
22 |
| Issue: |
11 |
| Pages: |
1865-76 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Coursey TG |
| Year: |
2016 |
| Journal: |
Am J Pathol |
| Title: |
Interferon-γ-Induced Unfolded Protein Response in Conjunctival Goblet Cells as a Cause of Mucin Deficiency in Sjögren Syndrome. |
| Volume: |
186 |
| Issue: |
6 |
| Pages: |
1547-58 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McElroy SJ |
| Year: |
2011 |
| Journal: |
Am J Physiol Gastrointest Liver Physiol |
| Title: |
Tumor necrosis factor receptor 1-dependent depletion of mucus in immature small intestine: a potential role in neonatal necrotizing enterocolitis. |
| Volume: |
301 |
| Issue: |
4 |
| Pages: |
G656-66 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Waddell A |
| Year: |
2019 |
| Journal: |
J Immunol |
| Title: |
IL-33 Induces Murine Intestinal Goblet Cell Differentiation Indirectly via Innate Lymphoid Cell IL-13 Secretion. |
| Volume: |
202 |
| Issue: |
2 |
| Pages: |
598-607 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yang W |
| Year: |
2003 |
| Journal: |
Cancer Res |
| Title: |
Targeted inactivation of p27kip1 is sufficient for large and small intestinal tumorigenesis in the mouse, which can be augmented by a Western-style high-risk diet. |
| Volume: |
63 |
| Issue: |
16 |
| Pages: |
4990-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nam KT |
| Year: |
2009 |
| Journal: |
Gastroenterology |
| Title: |
Amphiregulin-deficient mice develop spasmolytic polypeptide expressing metaplasia and intestinal metaplasia. |
| Volume: |
136 |
| Issue: |
4 |
| Pages: |
1288-96 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nishida K |
| Year: |
2009 |
| Journal: |
FASEB J |
| Title: |
Interleukin-18 is a crucial determinant of vulnerability of the mouse rectum to psychosocial stress. |
| Volume: |
23 |
| Issue: |
6 |
| Pages: |
1797-805 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pérez-Bosque A |
| Year: |
2015 |
| Journal: |
Am J Physiol Gastrointest Liver Physiol |
| Title: |
Dietary intervention with serum-derived bovine immunoglobulins protects barrier function in a mouse model of colitis. |
| Volume: |
308 |
| Issue: |
12 |
| Pages: |
G1012-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Katz JP |
| Year: |
2002 |
| Journal: |
Development |
| Title: |
The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon. |
| Volume: |
129 |
| Issue: |
11 |
| Pages: |
2619-28 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cha HR |
| Year: |
2010 |
| Journal: |
J Immunol |
| Title: |
Downregulation of Th17 cells in the small intestine by disruption of gut flora in the absence of retinoic acid. |
| Volume: |
184 |
| Issue: |
12 |
| Pages: |
6799-806 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang HH |
| Year: |
2004 |
| Journal: |
J Lipid Res |
| Title: |
Targeted disruption of the murine mucin gene 1 decreases susceptibility to cholesterol gallstone formation. |
| Volume: |
45 |
| Issue: |
3 |
| Pages: |
438-47 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Inagaki-Ohara K |
| Year: |
2014 |
| Journal: |
Oncogene |
| Title: |
Enhancement of leptin receptor signaling by SOCS3 deficiency induces development of gastric tumors in mice. |
| Volume: |
33 |
| Issue: |
1 |
| Pages: |
74-84 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bergström JH |
| Year: |
2016 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Gram-positive bacteria are held at a distance in the colon mucus by the lectin-like protein ZG16. |
| Volume: |
113 |
| Issue: |
48 |
| Pages: |
13833-13838 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Park KH |
| Year: |
2023 |
| Journal: |
Int J Mol Sci |
| Title: |
VDUP1 Deficiency Promotes the Severity of DSS-Induced Colitis in Mice by Inducing Macrophage Infiltration. |
| Volume: |
24 |
| Issue: |
17 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cantero-Recasens G |
| Year: |
2022 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
The ulcerative colitis-associated gene FUT8 regulates the quantity and quality of secreted mucins. |
| Volume: |
119 |
| Issue: |
43 |
| Pages: |
e2205277119 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Vega G |
| Year: |
2019 |
| Journal: |
Front Physiol |
| Title: |
Normal Calcium-Activated Anion Secretion in a Mouse Selectively Lacking TMEM16A in Intestinal Epithelium. |
| Volume: |
10 |
|
| Pages: |
694 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu C |
| Year: |
2013 |
| Journal: |
Am J Physiol Cell Physiol |
| Title: |
NHE8 plays an important role in mucosal protection via its effect on bacterial adhesion. |
| Volume: |
305 |
| Issue: |
1 |
| Pages: |
C121-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xu H |
| Year: |
2012 |
| Journal: |
Am J Physiol Gastrointest Liver Physiol |
| Title: |
Impaired mucin synthesis and bicarbonate secretion in the colon of NHE8 knockout mice. |
| Volume: |
303 |
| Issue: |
3 |
| Pages: |
G335-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sharba S |
| Year: |
2019 |
| Journal: |
Virulence |
| Title: |
Formyl peptide receptor 2 orchestrates mucosal protection against Citrobacter rodentium infection. |
| Volume: |
10 |
| Issue: |
1 |
| Pages: |
610-624 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bel S |
| Year: |
2012 |
| Journal: |
J Biol Chem |
| Title: |
Loss of TMF/ARA160 protein renders colonic mucus refractory to bacterial colonization and diminishes intestinal susceptibility to acute colitis. |
| Volume: |
287 |
| Issue: |
30 |
| Pages: |
25631-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zeineldin M |
| Year: |
2014 |
| Journal: |
Carcinogenesis |
| Title: |
Nuclear adenomatous polyposis coli suppresses colitis-associated tumorigenesis in mice. |
| Volume: |
35 |
| Issue: |
8 |
| Pages: |
1881-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Neumeyer V |
| Year: |
2019 |
| Journal: |
Cancers (Basel) |
| Title: |
Mutated Rnf43 Aggravates Helicobacter Pylori-Induced Gastric Pathology. |
| Volume: |
11 |
| Issue: |
3 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang X |
| Year: |
2021 |
| Journal: |
Front Cell Dev Biol |
| Title: |
Impaired Barrier Function and Immunity in the Colon of Aldo-Keto Reductase 1B8 Deficient Mice. |
| Volume: |
9 |
|
| Pages: |
632805 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Olson FJ |
| Year: |
2002 |
| Journal: |
J Biol Chem |
| Title: |
Blood group A glycosyltransferase occurring as alleles with high sequence difference is transiently induced during a Nippostrongylus brasiliensis parasite infection. |
| Volume: |
277 |
| Issue: |
17 |
| Pages: |
15044-52 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang R |
| Year: |
2012 |
| Journal: |
Am J Physiol Gastrointest Liver Physiol |
| Title: |
Type 2 cGMP-dependent protein kinase regulates proliferation and differentiation in the colonic mucosa. |
| Volume: |
303 |
| Issue: |
2 |
| Pages: |
G209-19 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dokoshi T |
| Year: |
2024 |
| Journal: |
Nat Commun |
| Title: |
Dermal injury drives a skin to gut axis that disrupts the intestinal microbiome and intestinal immune homeostasis in mice. |
| Volume: |
15 |
| Issue: |
1 |
| Pages: |
3009 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shekels LL |
| Year: |
1995 |
| Journal: |
Biochem J |
| Title: |
Mouse gastric mucin: cloning and chromosomal localization. |
| Volume: |
311 ( Pt 3) |
|
| Pages: |
775-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Than BL |
| Year: |
2014 |
| Journal: |
Oncogene |
| Title: |
The role of KCNQ1 in mouse and human gastrointestinal cancers. |
| Volume: |
33 |
| Issue: |
29 |
| Pages: |
3861-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bergstrom KS |
| Year: |
2008 |
| Journal: |
Infect Immun |
| Title: |
Modulation of intestinal goblet cell function during infection by an attaching and effacing bacterial pathogen. |
| Volume: |
76 |
| Issue: |
2 |
| Pages: |
796-811 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zavros Y |
| Year: |
2005 |
| Journal: |
Oncogene |
| Title: |
Chronic gastritis in the hypochlorhydric gastrin-deficient mouse progresses to adenocarcinoma. |
| Volume: |
24 |
| Issue: |
14 |
| Pages: |
2354-66 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu W |
| Year: |
2020 |
| Journal: |
Biosci Rep |
| Title: |
Dynamic characterization of intestinal metaplasia in the gastric corpus mucosa of Atp4a-deficient mice. |
| Volume: |
40 |
| Issue: |
2 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dekaney CM |
| Year: |
2019 |
| Journal: |
Cell Mol Gastroenterol Hepatol |
| Title: |
Mist1 Expression Is Required for Paneth Cell Maturation. |
| Volume: |
8 |
| Issue: |
4 |
| Pages: |
549-560 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Su D |
| Year: |
2016 |
| Journal: |
Front Physiol |
| Title: |
Vitamin D Signaling through Induction of Paneth Cell Defensins Maintains Gut Microbiota and Improves Metabolic Disorders and Hepatic Steatosis in Animal Models. |
| Volume: |
7 |
|
| Pages: |
498 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang R |
| Year: |
2014 |
| Journal: |
Cell Death Differ |
| Title: |
Type 2 cGMP-dependent protein kinase regulates homeostasis by blocking c-Jun N-terminal kinase in the colon epithelium. |
| Volume: |
21 |
| Issue: |
3 |
| Pages: |
427-37 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kaden-Volynets V |
| Year: |
2019 |
| Journal: |
Am J Physiol Gastrointest Liver Physiol |
| Title: |
Deletion of the Casp8 gene in mice results in ileocolitis, gut barrier dysfunction, and malassimilation, which can be partially attenuated by inulin or sodium butyrate. |
| Volume: |
317 |
| Issue: |
4 |
| Pages: |
G493-G507 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Das S |
| Year: |
2016 |
| Journal: |
Oncogene |
| Title: |
Mice deficient in Muc4 are resistant to experimental colitis and colitis-associated colorectal cancer. |
| Volume: |
35 |
| Issue: |
20 |
| Pages: |
2645-54 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Augenlicht LH |
| Year: |
2002 |
| Journal: |
J Nutr |
| Title: |
Short chain fatty acids and colon cancer. |
| Volume: |
132 |
| Issue: |
12 |
| Pages: |
3804S-3808S |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tamagawa Y |
| Year: |
2012 |
| Journal: |
Lab Invest |
| Title: |
Notch signaling pathway and Cdx2 expression in the development of Barrett's esophagus. |
| Volume: |
92 |
| Issue: |
6 |
| Pages: |
896-909 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Saxena A |
| Year: |
2013 |
| Journal: |
Int J Colorectal Dis |
| Title: |
Mucus and adiponectin deficiency: role in chronic inflammation-induced colon cancer. |
| Volume: |
28 |
| Issue: |
9 |
| Pages: |
1267-79 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cornick S |
| Year: |
2017 |
| Journal: |
mBio |
| Title: |
Entamoeba histolytica-Induced Mucin Exocytosis Is Mediated by VAMP8 and Is Critical in Mucosal Innate Host Defense. |
| Volume: |
8 |
| Issue: |
5 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bernardazzi C |
| Year: |
2020 |
| Journal: |
Am J Physiol Gastrointest Liver Physiol |
| Title: |
An indisputable role of NHE8 in mucosal protection. |
| Volume: |
319 |
| Issue: |
4 |
| Pages: |
G421-G431 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gerhard DS |
| Year: |
2004 |
| Journal: |
Genome Res |
| Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
| Volume: |
14 |
| Issue: |
10B |
| Pages: |
2121-7 |
|
•
•
•
•
•
|