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Search results 201 to 300 out of 6467 for Myc

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Type Details Score
Publication
23803853 | J:200609
First Author: Pourdehnad M
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Myc and mTOR converge on a common node in protein synthesis control that confers synthetic lethality in Myc-driven cancers.
Volume: 110
Issue: 29
Pages: 11988-93
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Publication
24444712 | J:211600
First Author: Cho H
Year: 2014
Journal: Cancer Discov
Title: RapidCaP, a novel GEM model for metastatic prostate cancer analysis and therapy, reveals myc as a driver of Pten-mutant metastasis.
Volume: 4
Issue: 3
Pages: 318-33
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Publication
8622900 | J:32921
First Author: Zörnig M
Year: 1996
Journal: Oncogene
Title: Zinc finger protein GFI-1 cooperates with myc and pim-1 in T-cell lymphomagenesis by reducing the requirements for IL-2.
Volume: 12
Issue: 8
Pages: 1789-801
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Publication
22869734 | J:188602
First Author: Spehalski E
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Oncogenic Myc translocations are independent of chromosomal location and orientation of the immunoglobulin heavy chain locus.
Volume: 109
Issue: 34
Pages: 13728-32
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Publication
26774856 | J:229985
First Author: Zhou W
Year: 2016
Journal: Am J Pathol
Title: Far Upstream Element Binding Protein Plays a Crucial Role in Embryonic Development, Hematopoiesis, and Stabilizing Myc Expression Levels.
Volume: 186
Issue: 3
Pages: 701-15
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Publication
1283123 | J:3579
First Author: Hirning-Folz U
Year: 1992
Journal: Cytogenet Cell Genet
Title: Aberrant Myc expression in the murine trisomy 15 syndrome is correlated with prolonged proliferation in spongiotrophoblast cells of the placenta.
Volume: 61
Issue: 4
Pages: 289-94
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Publication
18356293 | J:133578
First Author: Podsypanina K
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Oncogene cooperation in tumor maintenance and tumor recurrence in mouse mammary tumors induced by Myc and mutant Kras.
Volume: 105
Issue: 13
Pages: 5242-7
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Publication
16904610 | J:112704
First Author: Finch A
Year: 2006
Journal: Cancer Cell
Title: Bcl-xL gain of function and p19 ARF loss of function cooperate oncogenically with Myc in vivo by distinct mechanisms.
Volume: 10
Issue: 2
Pages: 113-20
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Publication
21641375 | J:173300
First Author: Sistrunk C
Year: 2011
Journal: Am J Pathol
Title: Skp2 is necessary for Myc-induced keratinocyte proliferation but dispensable for Myc oncogenic activity in the oral epithelium.
Volume: 178
Issue: 6
Pages: 2470-7
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Publication
20551174 | J:161202
First Author: van Riggelen J
Year: 2010
Journal: Genes Dev
Title: The interaction between Myc and Miz1 is required to antagonize TGFbeta-dependent autocrine signaling during lymphoma formation and maintenance.
Volume: 24
Issue: 12
Pages: 1281-94
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Publication
8290253 | J:16661
First Author: Roussel MF
Year: 1994
Journal: Oncogene
Title: Dual control of myc expression through a single DNA binding site targeted by ets family proteins and E2F-1.
Volume: 9
Issue: 2
Pages: 405-15
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Publication
20364083 | J:161484
First Author: Ahuja P
Year: 2010
Journal: J Clin Invest
Title: Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice.
Volume: 120
Issue: 5
Pages: 1494-505
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Publication
22184065 | J:183636
First Author: Neri F
Year: 2012
Journal: Mol Cell Biol
Title: Myc regulates the transcription of the PRC2 gene to control the expression of developmental genes in embryonic stem cells.
Volume: 32
Issue: 4
Pages: 840-51
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Publication
29777010 | J:264117
 
First Author: Nayak G
Year: 2018
Journal: Development
Title: Developmental vascular regression is regulated by a Wnt/β-catenin, MYC and CDKN1A pathway that controls cell proliferation and cell death.
Volume: 145
Issue: 12
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Publication
16477001 | J:107316
First Author: Prathapam T
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Activated Src abrogates the Myc requirement for the G0/G1 transition but not for the G1/S transition.
Volume: 103
Issue: 8
Pages: 2695-700
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Publication
11940659 | J:78929
First Author: McArthur GA
Year: 2002
Journal: Mol Cell Biol
Title: MAD1 and p27(KIP1) cooperate to promote terminal differentiation of granulocytes and to inhibit Myc expression and cyclin E-CDK2 activity.
Volume: 22
Issue: 9
Pages: 3014-23
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Publication
25246276 | J:273044
First Author: Zhu X
Year: 2014
Journal: Neoplasia
Title: Synergistic signaling of KRAS and thyroid hormone receptor β mutants promotes undifferentiated thyroid cancer through MYC up-regulation.
Volume: 16
Issue: 9
Pages: 757-69
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Publication
27752085 | J:254120
 
First Author: Villa Del Campo C
Year: 2016
Journal: Sci Rep
Title: Myc overexpression enhances of epicardial contribution to the developing heart and promotes extensive expansion of the cardiomyocyte population.
Volume: 6
Pages: 35366
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Publication
22464321 | -
First Author: Dang CV
Year: 2012
Journal: Cell
Title: MYC on the path to cancer.
Volume: 149
Issue: 1
Pages: 22-35
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Publication
2470008 | J:27616
First Author: Semsei I
Year: 1989
Journal: Oncogene
Title: Tissue and age specific expression of the myc proto-oncogene family throughout the life span of the C57BL/6J mouse strain.
Volume: 4
Issue: 4
Pages: 465-71
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Publication
28481866 | J:247825
First Author: Xin B
Year: 2017
Journal: Oncogene
Title: Critical role of Myc activation in mouse hepatocarcinogenesis induced by the activation of AKT and RAS pathways.
Volume: 36
Issue: 36
Pages: 5087-5097
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Publication
28003334 | J:277034
First Author: Myant KB
Year: 2017
Journal: EMBO Mol Med
Title: HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation.
Volume: 9
Issue: 2
Pages: 181-197
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Publication
30061166 | J:270575
 
First Author: Mastromina I
Year: 2018
Journal: Development
Title: Myc activity is required for maintenance of the neuromesodermal progenitor signalling network and for segmentation clock gene oscillations in mouse.
Volume: 145
Issue: 14
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Publication
25287161 | J:217184
First Author: Schubbert S
Year: 2014
Journal: Cancer Res
Title: Targeting the MYC and PI3K pathways eliminates leukemia-initiating cells in T-cell acute lymphoblastic leukemia.
Volume: 74
Issue: 23
Pages: 7048-59
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Publication
6205276 | J:7517
First Author: Gonda TJ
Year: 1984
Journal: Nature
Title: Expression of myb, myc and fos proto-oncogenes during the differentiation of a murine myeloid leukaemia.
Volume: 310
Issue: 5974
Pages: 249-51
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Protein
Q9EQS3
Organism: Mus musculus/domesticus
Length: 103  
Fragment?: false
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Publication
7981146 | J:20384
First Author: Malde P
Year: 1994
Journal: Int Immunol
Title: Disregulation of Myc expression in murine bone marrow cells results in an inability to proliferate in sub-optimal growth factor and an increased sensitivity to DNA damage.
Volume: 6
Issue: 8
Pages: 1169-76
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Publication
12015982 | J:76473
First Author: Pelengaris S
Year: 2002
Journal: Cell
Title: Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression.
Volume: 109
Issue: 3
Pages: 321-34
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Publication
8662079 | J:33541
First Author: Kovalchuk AL
Year: 1996
Journal: Immunogenetics
Title: DNA sequence analysis of the genetic recombination between Igh6 and Myc in an uncommon BALB/c plasmacytoma, TEPC 1194.
Volume: 44
Issue: 2
Pages: 151-6
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Allele
Myc<tm1.1(MYC)Gwbk> | MGI:5447463
 
Name: myelocytomatosis oncogene; targeted mutation 1.1, Georg W Bornkamm
Allele Type: Targeted
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Publication
10232373 | J:55341
 
First Author: Neil J
Year: 1999
Journal: Leukemia
Title: Identification of murine CBF alpha1, a runt domain transcription factor, as a putative Myc collaborator in T cell lymphoma.
Volume: 13 Suppl 1
Pages: S83-6
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Publication
9175477 | -
First Author: Grandori C
Year: 1997
Journal: Trends Biochem Sci
Title: Myc target genes.
Volume: 22
Issue: 5
Pages: 177-81
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Publication
31292135 | J:280780
First Author: Rosselot C
Year: 2019
Journal: Diabetes
Title: Myc Is Required for Adaptive β-Cell Replication in Young Mice but Is Not Sufficient in One-Year-Old Mice Fed With a High-Fat Diet.
Volume: 68
Issue: 10
Pages: 1934-1949
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Publication
19033191 | J:142249
First Author: Reed KR
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver.
Volume: 105
Issue: 48
Pages: 18919-23
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Publication
1644290 | J:1838
First Author: Mukherjee B
Year: 1992
Journal: Genes Dev
Title: Myc family oncoproteins function through a common pathway to transform normal cells in culture: cross-interference by Max and trans-acting dominant mutants.
Volume: 6
Issue: 8
Pages: 1480-92
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Publication
25784651 | J:312834
First Author: Yetil A
Year: 2015
Journal: Oncotarget
Title: p19ARF is a critical mediator of both cellular senescence and an innate immune response associated with MYC inactivation in mouse model of acute leukemia.
Volume: 6
Issue: 6
Pages: 3563-77
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Protein
P01108
Organism: Mus musculus/domesticus
Length: 439  
Fragment?: false
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Protein
F8WID3
Organism: Mus musculus/domesticus
Length: 454  
Fragment?: false
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Protein
Q6WDF1
Organism: Mus musculus/domesticus
Length: 187  
Fragment?: true
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Protein
F6PX41
Organism: Mus musculus/domesticus
Length: 453  
Fragment?: false
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Protein
Q8K3Z5
Organism: Mus musculus/domesticus
Length: 149  
Fragment?: true
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Protein
B2RSN1
Organism: Mus musculus/domesticus
Length: 454  
Fragment?: false
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Other Genome Feature
MGI:96800 | Lmyc2
Type: sequence_feature
Organism: mouse, laboratory
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Publication
18438430 | J:177147
First Author: Zhang Y
Year: 2008
Journal: Oncogene
Title: Pim kinase-dependent inhibition of c-Myc degradation.
Volume: 27
Issue: 35
Pages: 4809-19
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Publication
29067676 | J:258224
First Author: Pierre S
Year: 2018
Journal: Eur J Immunol
Title: Myc binding protein 2 suppresses M2-like phenotypes in macrophages during zymosan-induced inflammation in mice.
Volume: 48
Issue: 2
Pages: 239-249
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Publication
30862721 | J:274189
First Author: Tao R
Year: 2019
Journal: Cancer Res
Title: MYC Drives Group 3 Medulloblastoma through Transformation of Sox2+ Astrocyte Progenitor Cells.
Volume: 79
Issue: 8
Pages: 1967-1980
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Publication
33262248 | J:300751
First Author: Shin HY
Year: 2021
Journal: J Neurosci
Title: Role of Myc Proto-Oncogene as a Transcriptional Hub to Regulate the Expression of Regeneration-Associated Genes following Preconditioning Peripheral Nerve Injury.
Volume: 41
Issue: 3
Pages: 446-460
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Publication
6488314 | J:29013
First Author: Stewart TA
Year: 1984
Journal: Cell
Title: Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes.
Volume: 38
Issue: 3
Pages: 627-37
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Publication
28790107 | J:246541
First Author: Choi A
Year: 2017
Journal: Blood
Title: RUNX1 is required for oncogenic Myb and Myc enhancer activity in T-cell acute lymphoblastic leukemia.
Volume: 130
Issue: 15
Pages: 1722-1733
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Publication
3906410 | J:78177
First Author: Adams JM
Year: 1985
Journal: Nature
Title: The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice.
Volume: 318
Issue: 6046
Pages: 533-8
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Publication
30642836 | J:272568
 
First Author: Muñoz-Martín N
Year: 2019
Journal: Development
Title: Myc is dispensable for cardiomyocyte development but rescues Mycn-deficient hearts through functional replacement and cell competition.
Volume: 146
Issue: 3
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Other Genome Feature
MGI:98720 | Tg.Myc
Type: sequence_feature
Organism: mouse, laboratory
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UniProt Feature
UniProt Feature
Begin: 1
Description: Myc target protein 1
Type: chain
End: 188
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UniProt Feature
UniProt Feature
Begin: 1
Description: Myc proto-oncogene protein
Type: chain
End: 439
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UniProt Feature
UniProt Feature
Begin: 2
Description: Myc box-dependent-interacting protein 1
Type: chain
End: 588
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Strain
MGI:5499657 | B6.Cg-Myc<tm1.1(MYC)Gwbk>/Ieg
Attribute String: targeted mutation, mutant strain, congenic
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Genotype
Genotype
Symbol: Myc/Myc
Background: involves: BALB/cJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Publication
8521822 | J:29949
First Author: Hurlin PJ
Year: 1995
Journal: EMBO J
Title: Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation.
Volume: 14
Issue: 22
Pages: 5646-59
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Publication
10557294 | J:58511
First Author: Iritani BM
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: c-Myc enhances protein synthesis and cell size during B lymphocyte development.
Volume: 96
Issue: 23
Pages: 13180-5
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Publication
22860051 | J:189677
First Author: Lehmann FM
Year: 2012
Journal: PLoS One
Title: Humanized c-Myc mouse.
Volume: 7
Issue: 7
Pages: e42021
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Gene
292264 | Myct1
Type: gene
Organism: rat
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Gene
290447 | Mycbp2
Type: gene
Organism: rat
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Gene
60661 | Max
Type: gene
Organism: rat
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Gene
475323 | MYCBP
Type: gene
Organism: dog, domestic
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Gene
609969 | MAX
Type: gene
Organism: dog, domestic
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Gene
612005 | MYCT1
Type: gene
Organism: dog, domestic
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Gene
452608 | MYCBP2
Type: gene
Organism: chimpanzee
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Gene
452972 | MAX
Type: gene
Organism: chimpanzee
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Gene
736710 | MYCT1
Type: gene
Organism: chimpanzee
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Gene
476952 | MYCBP2
Type: gene
Organism: dog, domestic
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Gene
534496 | MYCBP2
Type: gene
Organism: cattle
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Gene
539291 | MYCBP
Type: gene
Organism: cattle
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Gene
540616 | MAX
Type: gene
Organism: cattle
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Gene
782134 | MYCT1
Type: gene
Organism: cattle
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Gene
100361133 | Mycbp
Type: gene
Organism: rat
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Gene
100609831 | MYCBP
Type: gene
Organism: chimpanzee
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Gene
100858676 | MAX
Type: gene
Organism: chicken
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Gene
418436 | MINA
Type: gene
Organism: chicken
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Gene
421641 | MYCT1
Type: gene
Organism: chicken
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Gene
770496 | MYCBP
Type: gene
Organism: chicken
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Gene
100537522 | myct1b
Type: gene
Organism: zebrafish
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Gene
30467 | max
Type: gene
Organism: zebrafish
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Gene
368439 | mycbp2
Type: gene
Organism: zebrafish
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Gene
563561 | LOC563561
Type: gene
Organism: zebrafish
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Gene
677757 | mycbp
Type: gene
Organism: zebrafish
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Gene
796556 | myct1a
Type: gene
Organism: zebrafish
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Gene
696734 | MYCBP2
Type: gene
Organism: macaque, rhesus
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Gene
708228 | MAX
Type: gene
Organism: macaque, rhesus
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Gene
711296 | MYCT1
Type: gene
Organism: macaque, rhesus
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Gene
715601 | MYCBP
Type: gene
Organism: macaque, rhesus
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Gene
101904335 | LOC101904335
Type: gene
Organism: cattle
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Gene
493570 | max
Type: gene
Organism: frog, western clawed
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Gene
549789 | mycbp
Type: gene
Organism: frog, western clawed
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Gene
780331 | myct1
Type: gene
Organism: frog, western clawed
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Publication
22158946 | J:181113
First Author: Robert F
Year: 2012
Journal: Cancer Res
Title: Targeting protein synthesis in a Myc/mTOR-driven model of anorexia-cachexia syndrome delays its onset and prolongs survival.
Volume: 72
Issue: 3
Pages: 747-56
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Publication
3258007 | J:81130
First Author: Harris AW
Year: 1988
Journal: J Exp Med
Title: The E mu-myc transgenic mouse. A model for high-incidence spontaneous lymphoma and leukemia of early B cells.
Volume: 167
Issue: 2
Pages: 353-71
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Publication
10698495 | J:60583
First Author: Blyth K
Year: 2000
Journal: Oncogene
Title: Sensitivity to myc-induced apoptosis is retained in spontaneous and transplanted lymphomas of CD2-mycER mice.
Volume: 19
Issue: 6
Pages: 773-82
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Publication
25384216 | J:219523
First Author: Dechow T
Year: 2014
Journal: J Clin Invest
Title: GP130 activation induces myeloma and collaborates with MYC.
Volume: 124
Issue: 12
Pages: 5263-74
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Publication
3924592 | J:7897
First Author: Cory S
Year: 1985
Journal: EMBO J
Title: Variant (6;15) translocations in murine plasmacytomas involve a chromosome 15 locus at least 72 kb from the c-myc oncogene.
Volume: 4
Issue: 3
Pages: 675-81
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Publication
3937724 | J:8193
First Author: Banerjee M
Year: 1985
Journal: EMBO J
Title: Mapping of the c-myc, pvt-1 and immunoglobulin kappa genes in relation to the mouse plasmacytoma-associated variant (6;15) translocation breakpoint.
Volume: 4
Issue: 12
Pages: 3183-8
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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