Type |
Details |
Score |
Publication |
First Author: |
Colpitts SL |
Year: |
2012 |
Journal: |
J Immunol |
Title: |
Cutting edge: the role of IFN-α receptor and MyD88 signaling in induction of IL-15 expression in vivo. |
Volume: |
188 |
Issue: |
6 |
Pages: |
2483-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Didovic S |
Year: |
2016 |
Journal: |
Eur J Immunol |
Title: |
Requirement of MyD88 signaling in keratinocytes for Langerhans cell migration and initiation of atopic dermatitis-like symptoms in mice. |
Volume: |
46 |
Issue: |
4 |
Pages: |
981-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Revaz-Breton M |
Year: |
2010 |
Journal: |
Eur J Immunol |
Title: |
The MyD88 protein 88 pathway is differently involved in immune responses induced by distinct substrains of Leishmania major. |
Volume: |
40 |
Issue: |
6 |
Pages: |
1697-707 |
|
•
•
•
•
•
|
Publication |
First Author: |
Banerjee A |
Year: |
2014 |
Journal: |
Infect Immun |
Title: |
Deficiency of the myeloid differentiation primary response molecule MyD88 leads to an early and rapid development of Helicobacter-induced gastric malignancy. |
Volume: |
82 |
Issue: |
1 |
Pages: |
356-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aleyas AG |
Year: |
2009 |
Journal: |
J Immunol |
Title: |
Functional modulation of dendritic cells and macrophages by Japanese encephalitis virus through MyD88 adaptor molecule-dependent and -independent pathways. |
Volume: |
183 |
Issue: |
4 |
Pages: |
2462-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
McAleer JP |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
The lipopolysaccharide adjuvant effect on T cells relies on nonoverlapping contributions from the MyD88 pathway and CD11c+ cells. |
Volume: |
179 |
Issue: |
10 |
Pages: |
6524-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ogimoto K |
Year: |
2006 |
Journal: |
Endocrinology |
Title: |
MyD88 is a key mediator of anorexia, but not weight loss, induced by lipopolysaccharide and interleukin-1 beta. |
Volume: |
147 |
Issue: |
9 |
Pages: |
4445-53 |
|
•
•
•
•
•
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Publication |
First Author: |
Lim JE |
Year: |
2012 |
Journal: |
Behav Brain Res |
Title: |
The effects of MyD88 deficiency on exploratory activity, anxiety, motor coordination, and spatial learning in C57BL/6 and APPswe/PS1dE9 mice. |
Volume: |
227 |
Issue: |
1 |
Pages: |
36-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kang SM |
Year: |
2011 |
Journal: |
J Virol |
Title: |
MyD88 plays an essential role in inducing B cells capable of differentiating into antibody-secreting cells after vaccination. |
Volume: |
85 |
Issue: |
21 |
Pages: |
11391-400 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Z |
Year: |
2009 |
Journal: |
Clin Immunol |
Title: |
AA28-67 domain within MyD88 suppresses c-myc activity and expression to regulate differentiation and function of dendritic cells. |
Volume: |
133 |
Issue: |
3 |
Pages: |
324-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wikstrom ME |
Year: |
2014 |
Journal: |
Eur J Immunol |
Title: |
The early monocytic response to cytomegalovirus infection is MyD88 dependent but occurs independently of common inflammatory cytokine signals. |
Volume: |
44 |
Issue: |
2 |
Pages: |
409-19 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen L |
Year: |
2010 |
Journal: |
J Immunol |
Title: |
Mice deficient in MyD88 Develop a Th2-dominant response and severe pathology in the upper genital tract following Chlamydia muridarum infection. |
Volume: |
184 |
Issue: |
5 |
Pages: |
2602-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ventura GM |
Year: |
2009 |
Journal: |
J Immunol |
Title: |
Lack of MyD88 protects the immunodeficient host against fatal lung inflammation triggered by the opportunistic bacteria Burkholderia cenocepacia. |
Volume: |
183 |
Issue: |
1 |
Pages: |
670-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Layoun A |
Year: |
2012 |
Journal: |
Inflammation |
Title: |
Bacterial cell wall constituents induce hepcidin expression in macrophages through MyD88 signaling. |
Volume: |
35 |
Issue: |
4 |
Pages: |
1500-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lord KA |
Year: |
1990 |
Journal: |
Oncogene |
Title: |
Nucleotide sequence and expression of a cDNA encoding MyD88, a novel myeloid differentiation primary response gene induced by IL6. |
Volume: |
5 |
Issue: |
7 |
Pages: |
1095-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Scanga CA |
Year: |
2002 |
Journal: |
J Immunol |
Title: |
Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells. |
Volume: |
168 |
Issue: |
12 |
Pages: |
5997-6001 |
|
•
•
•
•
•
|
Publication |
First Author: |
Han C |
Year: |
2010 |
Journal: |
Nat Immunol |
Title: |
Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b. |
Volume: |
11 |
Issue: |
8 |
Pages: |
734-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schenten D |
Year: |
2014 |
Journal: |
Immunity |
Title: |
Signaling through the adaptor molecule MyD88 in CD4+ T cells is required to overcome suppression by regulatory T cells. |
Volume: |
40 |
Issue: |
1 |
Pages: |
78-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tam MA |
Year: |
2009 |
Journal: |
Immunology |
Title: |
MyD88 and interferon-alpha/beta are differentially required for dendritic cell maturation but dispensable for development of protective memory against Listeria. |
Volume: |
128 |
Issue: |
3 |
Pages: |
429-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Behera AK |
Year: |
2006 |
Journal: |
Infect Immun |
Title: |
MyD88 deficiency results in tissue-specific changes in cytokine induction and inflammation in interleukin-18-independent mice infected with Borrelia burgdorferi. |
Volume: |
74 |
Issue: |
3 |
Pages: |
1462-70 |
|
•
•
•
•
•
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Publication |
First Author: |
Friedrich C |
Year: |
2017 |
Journal: |
PLoS Pathog |
Title: |
MyD88 signaling in dendritic cells and the intestinal epithelium controls immunity against intestinal infection with C. rodentium. |
Volume: |
13 |
Issue: |
5 |
Pages: |
e1006357 |
|
•
•
•
•
•
|
Publication |
First Author: |
Uaesoontrachoon K |
Year: |
2013 |
Journal: |
J Pathol |
Title: |
The effects of MyD88 deficiency on disease phenotype in dysferlin-deficient A/J mice: role of endogenous TLR ligands. |
Volume: |
231 |
Issue: |
2 |
Pages: |
199-209 |
|
•
•
•
•
•
|
Publication |
First Author: |
Layoun A |
Year: |
2018 |
Journal: |
Front Physiol |
Title: |
MyD88 Adaptor Protein Is Required for Appropriate Hepcidin Induction in Response to Dietary Iron Overload in Mice. |
Volume: |
9 |
|
Pages: |
159 |
|
•
•
•
•
•
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Publication |
First Author: |
Ribes S |
Year: |
2013 |
Journal: |
Infect Immun |
Title: |
Resistance of the brain to Escherichia coli K1 infection depends on MyD88 signaling and the contribution of neutrophils and monocytes. |
Volume: |
81 |
Issue: |
5 |
Pages: |
1810-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Leiguez E |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Critical role of TLR2 and MyD88 for functional response of macrophages to a group IIA-secreted phospholipase A2 from snake venom. |
Volume: |
9 |
Issue: |
4 |
Pages: |
e93741 |
|
•
•
•
•
•
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Publication |
First Author: |
Wenzel J |
Year: |
2011 |
Journal: |
Front Physiol |
Title: |
Measurement of TLR-Induced Macrophage Spreading by Automated Image Analysis: Differential Role of Myd88 and MAPK in Early and Late Responses. |
Volume: |
2 |
|
Pages: |
71 |
|
•
•
•
•
•
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Publication |
First Author: |
Lombardo E |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
TLR4-mediated survival of macrophages is MyD88 dependent and requires TNF-alpha autocrine signalling. |
Volume: |
178 |
Issue: |
6 |
Pages: |
3731-9 |
|
•
•
•
•
•
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Publication |
First Author: |
Into T |
Year: |
2018 |
Journal: |
Sci Rep |
Title: |
MyD88 signaling causes autoimmune sialadenitis through formation of high endothelial venules and upregulation of LTβ receptor-mediated signaling. |
Volume: |
8 |
Issue: |
1 |
Pages: |
14272 |
|
•
•
•
•
•
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Publication |
First Author: |
Gaddis DE |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
TLR4 signaling via MyD88 and TRIF differentially shape the CD4+ T cell response to Porphyromonas gingivalis hemagglutinin B. |
Volume: |
186 |
Issue: |
10 |
Pages: |
5772-83 |
|
•
•
•
•
•
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Publication |
First Author: |
Chang J |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
MyD88 is essential to sustain mTOR activation necessary to promote T helper 17 cell proliferation by linking IL-1 and IL-23 signaling. |
Volume: |
110 |
Issue: |
6 |
Pages: |
2270-5 |
|
•
•
•
•
•
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Publication |
First Author: |
Cocita C |
Year: |
2015 |
Journal: |
PLoS Pathog |
Title: |
Natural Killer Cell Sensing of Infected Cells Compensates for MyD88 Deficiency but Not IFN-I Activity in Resistance to Mouse Cytomegalovirus. |
Volume: |
11 |
Issue: |
5 |
Pages: |
e1004897 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lebeis SL |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
TLR signaling mediated by MyD88 is required for a protective innate immune response by neutrophils to Citrobacter rodentium. |
Volume: |
179 |
Issue: |
1 |
Pages: |
566-77 |
|
•
•
•
•
•
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Publication |
First Author: |
Silver K |
Year: |
2006 |
Journal: |
Eur J Immunol |
Title: |
TLR4, TLR9 and MyD88 are not required for the positive selection of autoreactive B cells into the primary repertoire. |
Volume: |
36 |
Issue: |
6 |
Pages: |
1404-12 |
|
•
•
•
•
•
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Publication |
First Author: |
Hölscher C |
Year: |
2008 |
Journal: |
Eur J Immunol |
Title: |
Containment of aerogenic Mycobacterium tuberculosis infection in mice does not require MyD88 adaptor function for TLR2, -4 and -9. |
Volume: |
38 |
Issue: |
3 |
Pages: |
680-94 |
|
•
•
•
•
•
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Publication |
First Author: |
Zhou S |
Year: |
2005 |
Journal: |
Eur J Immunol |
Title: |
MyD88 is critical for the development of innate and adaptive immunity during acute lymphocytic choriomeningitis virus infection. |
Volume: |
35 |
Issue: |
3 |
Pages: |
822-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Castoldi A |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
TLR2, TLR4 and the MYD88 signaling pathway are crucial for neutrophil migration in acute kidney injury induced by sepsis. |
Volume: |
7 |
Issue: |
5 |
Pages: |
e37584 |
|
•
•
•
•
•
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Publication |
First Author: |
Shin OS |
Year: |
2008 |
Journal: |
Infect Immun |
Title: |
Distinct roles for MyD88 and Toll-like receptors 2, 5, and 9 in phagocytosis of Borrelia burgdorferi and cytokine induction. |
Volume: |
76 |
Issue: |
6 |
Pages: |
2341-51 |
|
•
•
•
•
•
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Publication |
First Author: |
Johnson AC |
Year: |
2008 |
Journal: |
J Biol Chem |
Title: |
MyD88 functions as a negative regulator of TLR3/TRIF-induced corneal inflammation by inhibiting activation of c-Jun N-terminal kinase. |
Volume: |
283 |
Issue: |
7 |
Pages: |
3988-96 |
|
•
•
•
•
•
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Publication |
First Author: |
Lee JY |
Year: |
2003 |
Journal: |
J Biol Chem |
Title: |
Reciprocal modulation of Toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids. |
Volume: |
278 |
Issue: |
39 |
Pages: |
37041-51 |
|
•
•
•
•
•
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Publication |
First Author: |
Suvarna S |
Year: |
2008 |
Journal: |
Br J Haematol |
Title: |
Platelet factor 4-heparin complexes trigger immune responses independently of the MyD88 pathway. |
Volume: |
142 |
Issue: |
4 |
Pages: |
671-3 |
|
•
•
•
•
•
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Publication |
First Author: |
Khovananth K |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Altering a highly conserved residue in the MyD88 TIR domain using ENU results in normal function |
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•
•
•
•
•
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Publication |
First Author: |
Griffin C |
Year: |
2018 |
Journal: |
J Biol Chem |
Title: |
TLR4, TRIF, and MyD88 are essential for myelopoiesis and CD11c+ adipose tissue macrophage production in obese mice. |
Volume: |
293 |
Issue: |
23 |
Pages: |
8775-8786 |
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•
•
•
•
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Publication |
First Author: |
Sundquist M |
Year: |
2009 |
Journal: |
J Leukoc Biol |
Title: |
Salmonella induces death of CD8alpha(+) dendritic cells but not CD11c(int)CD11b(+) inflammatory cells in vivo via MyD88 and TNFR1. |
Volume: |
85 |
Issue: |
2 |
Pages: |
225-34 |
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•
•
•
•
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Publication |
First Author: |
Ives A |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
MyD88 and TLR9 dependent immune responses mediate resistance to Leishmania guyanensis infections, irrespective of Leishmania RNA virus burden. |
Volume: |
9 |
Issue: |
5 |
Pages: |
e96766 |
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•
•
•
•
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Publication |
First Author: |
Groom JR |
Year: |
2007 |
Journal: |
J Exp Med |
Title: |
BAFF and MyD88 signals promote a lupuslike disease independent of T cells. |
Volume: |
204 |
Issue: |
8 |
Pages: |
1959-71 |
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•
•
•
•
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Publication |
First Author: |
Rabeony H |
Year: |
2015 |
Journal: |
Eur J Immunol |
Title: |
IMQ-induced skin inflammation in mice is dependent on IL-1R1 and MyD88 signaling but independent of the NLRP3 inflammasome. |
Volume: |
45 |
Issue: |
10 |
Pages: |
2847-57 |
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•
•
•
•
•
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Publication |
First Author: |
Weiss G |
Year: |
2012 |
Journal: |
J Immunol |
Title: |
MyD88 drives the IFN-β response to Lactobacillus acidophilus in dendritic cells through a mechanism involving IRF1, IRF3, and IRF7. |
Volume: |
189 |
Issue: |
6 |
Pages: |
2860-8 |
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•
•
•
•
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Publication |
First Author: |
Frazer LC |
Year: |
2013 |
Journal: |
J Immunol |
Title: |
CD4+ T cell expression of MyD88 is essential for normal resolution of Chlamydia muridarum genital tract infection. |
Volume: |
191 |
Issue: |
8 |
Pages: |
4269-79 |
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•
•
•
•
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Publication |
First Author: |
Jhingran A |
Year: |
2015 |
Journal: |
PLoS Pathog |
Title: |
Compartment-specific and sequential role of MyD88 and CARD9 in chemokine induction and innate defense during respiratory fungal infection. |
Volume: |
11 |
Issue: |
1 |
Pages: |
e1004589 |
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•
•
•
•
•
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Publication |
First Author: |
Bonnert TP |
Year: |
1997 |
Journal: |
FEBS Lett |
Title: |
The cloning and characterization of human MyD88: a member of an IL-1 receptor related family. |
Volume: |
402 |
Issue: |
1 |
Pages: |
81-4 |
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•
•
•
•
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Publication |
First Author: |
Goff PH |
Year: |
2017 |
Journal: |
J Virol |
Title: |
Synthetic Toll-Like Receptor 4 (TLR4) and TLR7 Ligands Work Additively via MyD88 To Induce Protective Antiviral Immunity in Mice. |
Volume: |
91 |
Issue: |
19 |
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•
•
•
•
•
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Publication |
First Author: |
Ghita L |
Year: |
2021 |
Journal: |
Sci Immunol |
Title: |
MyD88 signaling by neurons induces chemokines that recruit protective leukocytes to the virus-infected CNS. |
Volume: |
6 |
Issue: |
60 |
|
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•
•
•
•
•
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Publication |
First Author: |
Shindou H |
Year: |
2005 |
Journal: |
J Immunol |
Title: |
Priming effect of lipopolysaccharide on acetyl-coenzyme A:lyso-platelet-activating factor acetyltransferase is MyD88 and TRIF independent. |
Volume: |
175 |
Issue: |
2 |
Pages: |
1177-83 |
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•
•
•
•
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Publication |
First Author: |
Schiechl G |
Year: |
2011 |
Journal: |
J Clin Invest |
Title: |
Tumor development in murine ulcerative colitis depends on MyD88 signaling of colonic F4/80+CD11b(high)Gr1(low) macrophages. |
Volume: |
121 |
Issue: |
5 |
Pages: |
1692-708 |
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•
•
•
•
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Publication |
First Author: |
Yang B |
Year: |
2022 |
Journal: |
Biochim Biophys Acta Mol Basis Dis |
Title: |
Macrophage-specific MyD88 deletion and pharmacological inhibition prevents liver damage in non-alcoholic fatty liver disease via reducing inflammatory response. |
Volume: |
1868 |
Issue: |
10 |
Pages: |
166480 |
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•
•
•
•
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Publication |
First Author: |
Bolz DD |
Year: |
2004 |
Journal: |
J Immunol |
Title: |
MyD88 plays a unique role in host defense but not arthritis development in Lyme disease. |
Volume: |
173 |
Issue: |
3 |
Pages: |
2003-10 |
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•
•
•
•
•
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Publication |
First Author: |
Roger T |
Year: |
2010 |
Journal: |
Infect Immun |
Title: |
Role of MyD88 and Toll-like receptors 2 and 4 in the sensing of Parachlamydia acanthamoebae. |
Volume: |
78 |
Issue: |
12 |
Pages: |
5195-201 |
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•
•
•
•
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Publication |
First Author: |
Bhoj VG |
Year: |
2008 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
MAVS and MyD88 are essential for innate immunity but not cytotoxic T lymphocyte response against respiratory syncytial virus. |
Volume: |
105 |
Issue: |
37 |
Pages: |
14046-51 |
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•
•
•
•
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Publication |
First Author: |
Re SL |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Uncoupling between inflammatory and fibrotic responses to silica: evidence from MyD88 knockout mice. |
Volume: |
9 |
Issue: |
7 |
Pages: |
e99383 |
|
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•
•
•
•
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Publication |
First Author: |
Owens AP 3rd |
Year: |
2011 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
MyD88 deficiency attenuates angiotensin II-induced abdominal aortic aneurysm formation independent of signaling through Toll-like receptors 2 and 4. |
Volume: |
31 |
Issue: |
12 |
Pages: |
2813-9 |
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•
•
•
•
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Publication |
First Author: |
Burns K |
Year: |
1998 |
Journal: |
J Biol Chem |
Title: |
MyD88, an adapter protein involved in interleukin-1 signaling. |
Volume: |
273 |
Issue: |
20 |
Pages: |
12203-9 |
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•
•
•
•
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Publication |
First Author: |
Saxena A |
Year: |
2011 |
Journal: |
Cardiovasc Res |
Title: |
The vascular repair process after injury of the carotid artery is regulated by IL-1RI and MyD88 signalling. |
Volume: |
91 |
Issue: |
2 |
Pages: |
350-7 |
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•
•
•
•
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Publication |
First Author: |
Jiang Z |
Year: |
2006 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis. |
Volume: |
103 |
Issue: |
29 |
Pages: |
10961-6 |
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•
•
•
•
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Publication |
First Author: |
Vaishnava S |
Year: |
2011 |
Journal: |
Science |
Title: |
The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine. |
Volume: |
334 |
Issue: |
6053 |
Pages: |
255-8 |
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•
•
•
•
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Publication |
First Author: |
Sukhumavasi W |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
TLR adaptor MyD88 is essential for pathogen control during oral toxoplasma gondii infection but not adaptive immunity induced by a vaccine strain of the parasite. |
Volume: |
181 |
Issue: |
5 |
Pages: |
3464-73 |
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•
•
•
•
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Publication |
First Author: |
Yamawaki Y |
Year: |
2022 |
Journal: |
Front Physiol |
Title: |
Peripheral Immune Activation in Mice Elicits Unfolded Protein Responses Independent on MyD88 Pathway in the Liver but not the Hypothalamus and Hippocampus. |
Volume: |
13 |
|
Pages: |
854538 |
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Publication |
First Author: |
Muleta KG |
Year: |
2022 |
Journal: |
Front Immunol |
Title: |
Rotavirus-Induced Expansion of Antigen-Specific CD8 T Cells Does Not Require Signaling via TLR3, MyD88 or the Type I Interferon Receptor. |
Volume: |
13 |
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Pages: |
814491 |
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Publication |
First Author: |
Teichmann LL |
Year: |
2013 |
Journal: |
Immunity |
Title: |
Signals via the adaptor MyD88 in B cells and DCs make distinct and synergistic contributions to immune activation and tissue damage in lupus. |
Volume: |
38 |
Issue: |
3 |
Pages: |
528-40 |
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•
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Publication |
First Author: |
Dear JW |
Year: |
2006 |
Journal: |
Kidney Int |
Title: |
Sepsis-induced organ failure is mediated by different pathways in the kidney and liver: acute renal failure is dependent on MyD88 but not renal cell apoptosis. |
Volume: |
69 |
Issue: |
5 |
Pages: |
832-6 |
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•
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Publication |
First Author: |
Ko HJ |
Year: |
2009 |
Journal: |
J Immunol |
Title: |
Innate immunity mediated by MyD88 signal is not essential for induction of lipopolysaccharide-specific B cell responses but is indispensable for protection against Salmonella enterica serovar Typhimurium infection. |
Volume: |
182 |
Issue: |
4 |
Pages: |
2305-12 |
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•
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Publication |
First Author: |
Singh MV |
Year: |
2015 |
Journal: |
Hypertension |
Title: |
Dual Activation of TRIF and MyD88 Adaptor Proteins by Angiotensin II Evokes Opposing Effects on Pressure, Cardiac Hypertrophy, and Inflammatory Gene Expression. |
Volume: |
66 |
Issue: |
3 |
Pages: |
647-56 |
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Publication |
First Author: |
Andreakos E |
Year: |
2004 |
Journal: |
Blood |
Title: |
Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP. |
Volume: |
103 |
Issue: |
6 |
Pages: |
2229-37 |
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•
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Publication |
First Author: |
Burns K |
Year: |
2003 |
Journal: |
J Exp Med |
Title: |
Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4. |
Volume: |
197 |
Issue: |
2 |
Pages: |
263-8 |
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•
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Publication |
First Author: |
Pattabiraman G |
Year: |
2017 |
Journal: |
J Biol Chem |
Title: |
The R753Q polymorphism in Toll-like receptor 2 (TLR2) attenuates innate immune responses to mycobacteria and impairs MyD88 adapter recruitment to TLR2. |
Volume: |
292 |
Issue: |
25 |
Pages: |
10685-10695 |
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•
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Publication |
First Author: |
Hardiman G |
Year: |
1997 |
Journal: |
Genomics |
Title: |
Genetic structure and chromosomal mapping of MyD88. |
Volume: |
45 |
Issue: |
2 |
Pages: |
332-9 |
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•
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Publication |
First Author: |
von Bernuth H |
Year: |
2008 |
Journal: |
Science |
Title: |
Pyogenic bacterial infections in humans with MyD88 deficiency. |
Volume: |
321 |
Issue: |
5889 |
Pages: |
691-6 |
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•
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Publication |
First Author: |
Togbe D |
Year: |
2006 |
Journal: |
Lab Invest |
Title: |
Nonredundant roles of TIRAP and MyD88 in airway response to endotoxin, independent of TRIF, IL-1 and IL-18 pathways. |
Volume: |
86 |
Issue: |
11 |
Pages: |
1126-35 |
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•
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Publication |
First Author: |
Brandl K |
Year: |
2010 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands. |
Volume: |
107 |
Issue: |
46 |
Pages: |
19967-72 |
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Publication |
First Author: |
de Almeida LA |
Year: |
2011 |
Journal: |
PLoS One |
Title: |
MyD88 and STING signaling pathways are required for IRF3-mediated IFN-β induction in response to Brucella abortus infection. |
Volume: |
6 |
Issue: |
8 |
Pages: |
e23135 |
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•
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Publication |
First Author: |
Brandl K |
Year: |
2007 |
Journal: |
J Exp Med |
Title: |
MyD88-mediated signals induce the bactericidal lectin RegIII gamma and protect mice against intestinal Listeria monocytogenes infection. |
Volume: |
204 |
Issue: |
8 |
Pages: |
1891-900 |
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Strain |
Attribute String: |
congenic, mutant strain, targeted mutation |
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Publication |
First Author: |
Bello-Irizarry SN |
Year: |
2012 |
Journal: |
Infect Immun |
Title: |
The alveolar epithelial cell chemokine response to pneumocystis requires adaptor molecule MyD88 and interleukin-1 receptor but not toll-like receptor 2 or 4. |
Volume: |
80 |
Issue: |
11 |
Pages: |
3912-20 |
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•
•
•
•
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Publication |
First Author: |
Naiki Y |
Year: |
2005 |
Journal: |
J Biol Chem |
Title: |
MyD88 is pivotal for the early inflammatory response and subsequent bacterial clearance and survival in a mouse model of Chlamydia pneumoniae pneumonia. |
Volume: |
280 |
Issue: |
32 |
Pages: |
29242-9 |
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•
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•
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Publication |
First Author: |
Yauch LE |
Year: |
2004 |
Journal: |
Infect Immun |
Title: |
Involvement of CD14, toll-like receptors 2 and 4, and MyD88 in the host response to the fungal pathogen Cryptococcus neoformans in vivo. |
Volume: |
72 |
Issue: |
9 |
Pages: |
5373-82 |
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•
•
•
•
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Publication |
First Author: |
Takaki H |
Year: |
2013 |
Journal: |
J Immunol |
Title: |
The MyD88 pathway in plasmacytoid and CD4+ dendritic cells primarily triggers type I IFN production against measles virus in a mouse infection model. |
Volume: |
191 |
Issue: |
9 |
Pages: |
4740-7 |
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•
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Publication |
First Author: |
Macedo L |
Year: |
2007 |
Journal: |
Am J Pathol |
Title: |
Wound healing is impaired in MyD88-deficient mice: a role for MyD88 in the regulation of wound healing by adenosine A2A receptors. |
Volume: |
171 |
Issue: |
6 |
Pages: |
1774-88 |
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•
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Publication |
First Author: |
Alkanani AK |
Year: |
2014 |
Journal: |
Diabetes |
Title: |
Induction of diabetes in the RIP-B7.1 mouse model is critically dependent on TLR3 and MyD88 pathways and is associated with alterations in the intestinal microbiome. |
Volume: |
63 |
Issue: |
2 |
Pages: |
619-31 |
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•
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•
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Publication |
First Author: |
Su SB |
Year: |
2005 |
Journal: |
J Immunol |
Title: |
Essential role of the MyD88 pathway, but nonessential roles of TLRs 2, 4, and 9, in the adjuvant effect promoting Th1-mediated autoimmunity. |
Volume: |
175 |
Issue: |
10 |
Pages: |
6303-10 |
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•
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Publication |
First Author: |
Cadman ET |
Year: |
2008 |
Journal: |
Infect Immun |
Title: |
Alterations of splenic architecture in malaria are induced independently of Toll-like receptors 2, 4, and 9 or MyD88 and may affect antibody affinity. |
Volume: |
76 |
Issue: |
9 |
Pages: |
3924-31 |
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•
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Publication |
First Author: |
Aikawa T |
Year: |
2015 |
Journal: |
Hum Mol Genet |
Title: |
Loss of MyD88 alters neuroinflammatory response and attenuates early Purkinje cell loss in a spinocerebellar ataxia type 6 mouse model. |
Volume: |
24 |
Issue: |
17 |
Pages: |
4780-91 |
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•
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Publication |
First Author: |
Park SM |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
MyD88 signaling is not essential for induction of antigen-specific B cell responses but is indispensable for protection against Streptococcus pneumoniae infection following oral vaccination with attenuated Salmonella expressing PspA antigen. |
Volume: |
181 |
Issue: |
9 |
Pages: |
6447-55 |
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•
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Publication |
First Author: |
Martin DA |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
Autoimmunity stimulated by adoptively transferred dendritic cells is initiated by both alphabeta and gammadelta T cells but does not require MyD88 signaling. |
Volume: |
179 |
Issue: |
9 |
Pages: |
5819-28 |
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•
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Publication |
First Author: |
Khan AQ |
Year: |
2005 |
Journal: |
Infect Immun |
Title: |
Both innate immunity and type 1 humoral immunity to Streptococcus pneumoniae are mediated by MyD88 but differ in their relative levels of dependence on toll-like receptor 2. |
Volume: |
73 |
Issue: |
1 |
Pages: |
298-307 |
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•
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•
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Publication |
First Author: |
Chen Z |
Year: |
2015 |
Journal: |
J Biol Chem |
Title: |
IL-1R/TLR2 through MyD88 Divergently Modulates Osteoclastogenesis through Regulation of Nuclear Factor of Activated T Cells c1 (NFATc1) and B Lymphocyte-induced Maturation Protein-1 (Blimp1). |
Volume: |
290 |
Issue: |
50 |
Pages: |
30163-74 |
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Publication |
First Author: |
Talbot S |
Year: |
2009 |
Journal: |
Immunology |
Title: |
Toll-like receptor 4 signalling through MyD88 is essential to control Salmonella enterica serovar typhimurium infection, but not for the initiation of bacterial clearance. |
Volume: |
128 |
Issue: |
4 |
Pages: |
472-83 |
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•
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Publication |
First Author: |
Krummen M |
Year: |
2010 |
Journal: |
J Leukoc Biol |
Title: |
Release of IL-12 by dendritic cells activated by TLR ligation is dependent on MyD88 signaling, whereas TRIF signaling is indispensable for TLR synergy. |
Volume: |
88 |
Issue: |
1 |
Pages: |
189-99 |
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•
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•
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Publication |
First Author: |
Nagarajan UM |
Year: |
2011 |
Journal: |
Infect Immun |
Title: |
MyD88 deficiency leads to decreased NK cell gamma interferon production and T cell recruitment during Chlamydia muridarum genital tract infection, but a predominant Th1 response and enhanced monocytic inflammation are associated with infection resolution. |
Volume: |
79 |
Issue: |
1 |
Pages: |
486-98 |
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•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
109
 |
Fragment?: |
true |
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•
|
HT Experiment |
Series Id: |
GSE17268 |
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
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Publication |
First Author: |
Sweet RA |
Year: |
2017 |
Journal: |
J Immunol |
Title: |
B Cell-Extrinsic Myd88 and Fcer1g Negatively Regulate Autoreactive and Normal B Cell Immune Responses. |
Volume: |
199 |
Issue: |
3 |
Pages: |
885-893 |
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