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Search results 201 to 252 out of 252 for Nat10

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Type Details Score
HT Experiment
GSE274007 | The effects of NAT10 on heart development
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE295333 | Identification of ribosome-protected mRNA fragments (RPFs) associated with NAT10 in mouse hearts
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE295332 | The effects of NAT10 on heart development in mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Allele
Nat10<em2Smoc> | MGI:7291235
Name: N-acetyltransferase 10; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:7718161 | C57BL/6JSmoc-Nat10<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Nat10<em1Smoc> | MGI:7291234
Name: N-acetyltransferase 10; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:7623442 | C57BL/6JSmoc-Nat10<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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HT Experiment
GSE254288 | NAT10-mediated mRNA N4-acetylation is Essential for the Translational Regulation During Oocyte Meiotic Maturation in Mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Protein Domain
IPR013562 | TmcA/NAT10_N
Type: Domain
Description: This entry represents a domain found at the N-terminal of TmcA from bacteria and NAT10 from eukaryotes.The bacterial tRNA(Met) cytidine acetyltransferase (TmcA) catalyses the formation of N(4)-acetylcytidine (ac4C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and either ATP or GTP []. This modification is thought to ensure precise recognition of the AUG codon by strengthening C-G base-pair interaction and also prevent misrecognition of the near cognate AUA codon []. RNA cytidine acetyltransferas (NAT10) are RNA cytosine acetyltransferases with specificity toward both 18S rRNA and tRNAs and contain additional putative nuclear and nucleolar localisation signals (NLS and NoLS respectively) [, , ].
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Protein Coding Gene
MGI:2444479 | Thumpd1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0030382 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0032916 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0032899 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0032831 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0032904 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0032614 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2444479 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0033410 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0031942 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0032587 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0032739 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0032692 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0032833 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0032724 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0033430 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0031650 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0032055 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0013593 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0016238 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:3614475
Assay Type: RT-PCR
Annotation Date: 2006-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:3616221
Age: embryonic day 13.5
Specimen Label: RT-PCR E13.5 brain
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3614475
Assay Type: RT-PCR
Annotation Date: 2006-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:3616221
Age: postnatal day 0
Specimen Label: RT-PCR P0 brain
Detected: false
Specimen Num: 2
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Publication
25402480 | -
First Author: Taoka M
Year: 2014
Journal: PLoS One
Title: RNA cytidine acetyltransferase of small-subunit ribosomal RNA: identification of acetylation sites and the responsible acetyltransferase in fission yeast, Schizosaccharomyces pombe.
Volume: 9
Issue: 11
Pages: e112156
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Publication
31491951 | -
 
First Author: Sleiman S
Year: 2019
Journal: Cells
Title: Recent Advances on the Structure and Function of RNA Acetyltransferase Kre33/NAT10.
Volume: 8
Issue: 9
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Protein
A2BH46
Organism: Mus musculus/domesticus
Length: 186  
Fragment?: true
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Publication
30449621 | -
First Author: Arango D
Year: 2018
Journal: Cell
Title: Acetylation of Cytidine in mRNA Promotes Translation Efficiency.
Volume: 175
Issue: 7
Pages: 1872-1886.e24
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Publication
35679869 | -
First Author: Arango D
Year: 2022
Journal: Mol Cell
Title: Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine.
Volume: 82
Issue: 15
Pages: 2797-2814.e11
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Protein Domain
IPR007807 | TcmA/NAT10_helicase
Type: Domain
Description: This domain contains a P-loop (Walker A) motif, suggesting that it has ATPase activity, and a Walker B motif. It is found in NAT10 from eukaryotes and TmcA from prokaryotes. In NAT10, this domain catalyses the formation of N4-acetylcytidine (ac4C) modification on mRNAs, 18S rRNA and tRNAs [, , ]. In TmcA, it may function as an RNA helicase motor (driven by ATP hydrolysis) which delivers the wobble base to the active centre of the GCN5-related N-acetyltransferase (GNAT) domain [].The bacterial tRNA(Met) cytidine acetyltransferase (TmcA) catalyses the formation of N(4)-acetylcytidine (ac4C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and either ATP or GTP []. This modification is thought to ensure precise recognition of the AUG codon by strengthening C-G base-pair interaction and also prevent misrecognition of the near cognate AUA codon []. RNA cytidine acetyltransferas (NAT10) are RNA cytosine acetyltransferases with specificity toward both 18S rRNA and tRNAs and contain additional putative nuclear and nucleolar localisation signals (NLS and NoLS respectively) [, , ].
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Publication
19322199 | -
First Author: Chimnaronk S
Year: 2009
Journal: EMBO J
Title: RNA helicase module in an acetyltransferase that modifies a specific tRNA anticodon.
Volume: 28
Issue: 9
Pages: 1362-73
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Publication
18668122 | -
First Author: Ikeuchi Y
Year: 2008
Journal: EMBO J
Title: The RNA acetyltransferase driven by ATP hydrolysis synthesizes N4-acetylcytidine of tRNA anticodon.
Volume: 27
Issue: 16
Pages: 2194-203
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Publication
40106564 | J:363949
First Author: Thalalla Gamage S
Year: 2025
Journal: Sci Adv
Title: Transfer RNA acetylation regulates in vivo mammalian stress signaling.
Volume: 11
Issue: 12
Pages: eads2923
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Publication
17525270 | J:122161
First Author: Blackburn AC
Year: 2007
Journal: Am J Pathol
Title: Genetic mapping in mice identifies DMBT1 as a candidate modifier of mammary tumors and breast cancer risk.
Volume: 170
Issue: 6
Pages: 2030-41
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Publication
15815685 | J:99489
First Author: Choi P
Year: 2005
Journal: Genes Immun
Title: Linkage analysis of the genetic determinants of T-cell IL-4 secretion, and identification of Flj20274 as a putative candidate gene.
Volume: 6
Issue: 4
Pages: 290-7
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Publication
16033648 | J:103446
 
First Author: McKee AE
Year: 2005
Journal: BMC Dev Biol
Title: A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.
Volume: 5
Pages: 14
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Publication
16919269 | J:112701
First Author: Bailey PJ
Year: 2006
Journal: Exp Cell Res
Title: A global genomic transcriptional code associated with CNS-expressed genes.
Volume: 312
Issue: 16
Pages: 3108-19
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:73796
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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