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Search results 201 to 226 out of 226 for Nek1

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Type Details Score
Allele  
Name: modifier of Nek1 (NIMA-related expressed kinase 1, kidney weight; CAST/Ei
Allele Type: QTL
Interaction Experiment
Description: Nek1 and TAZ interact to maintain normal levels of polycystin 2.
Allele  
Name: modifier of Nek1 (NIMA-related expressed kinase 1), kidney weight and hematocrit; CAST/Ei
Allele Type: QTL
Allele  
Name: modifier of Nek1 (NIMA-related expressed kinase 1), kidney weight and hematocrit; C57BL/6J
Allele Type: QTL
Genotype
Symbol: Mnek1c/Mnek1c
Background: involves: C57BL/6J-Nek1/+ * CAST/Ei
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Mnek1b/Mnek1b
Background: involves: C57BL/6J-Nek1/+ * CAST/Ei
Zygosity: hm
Has Mutant Allele: true
DO Term
Genotype
Symbol: Mnek1a/Mnek1a
Background: involves: C57BL/6J-Nek1/+ * CAST/Ei
Zygosity: hm
Has Mutant Allele: true
Allele
Name: NIMA (never in mitosis gene a)-related expressed kinase 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Genotype
Symbol: Mnek1b/Mnek1b
Background: involves: C57BL/6J-Nek1/+ * CAST/Ei
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Mnek1c/Mnek1c
Background: involves: C57BL/6J-Nek1/+ * CAST/Ei
Zygosity: ht
Has Mutant Allele: true
DO Term
Allele
Name: NIMA (never in mitosis gene a)-related expressed kinase 1; endonuclease-mediated mutation 13, Cathy Lutz
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence
DO Term
Strain
Attribute String: mutant strain, endonuclease-mediated mutation, coisogenic
Protein Domain
Type: Family
Description: This family includes Protein chibby homolog 2 (also known as Spermatid-associated protein). The function of this family is unclear. However, mouse spermatid-associated protein (SPERT, also known as Nurit) can form homodimers and can bind to NEK1 kinase. Its expression is restricted to the flower-like structure in spermatids [].
Protein
Organism: Mus musculus/domesticus
Length: 446  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 419  
Fragment?: false
Publication
First Author: Hayashi K
Year: 1999
Journal: Biochem Biophys Res Commun
Title: Activity and substrate specificity of the murine STK2 Serine/Threonine kinase that is structurally related to the mitotic regulator protein NIMA of Aspergillus nidulans.
Volume: 264
Issue: 2
Pages: 449-56
Publication
First Author: Zhu Y
Year: 2020
Journal: Mol Cell
Title: Dynamic Regulation of ME1 Phosphorylation and Acetylation Affects Lipid Metabolism and Colorectal Tumorigenesis.
Volume: 77
Issue: 1
Pages: 138-149.e5
Publication
First Author: Tanaka K
Year: 1999
Journal: J Biol Chem
Title: Cloning and characterization of the murine Nek3 protein kinase, a novel member of the NIMA family of putative cell cycle regulators.
Volume: 274
Issue: 19
Pages: 13491-7
Publication
First Author: Levedakou EN
Year: 1994
Journal: Oncogene
Title: Two novel human serine/threonine kinases with homologies to the cell cycle regulating Xenopus MO15, and NIMA kinases: cloning and characterization of their expression pattern.
Volume: 9
Issue: 7
Pages: 1977-88
Publication
First Author: Ballif BA
Year: 2004
Journal: Mol Cell Proteomics
Title: Phosphoproteomic analysis of the developing mouse brain.
Volume: 3
Issue: 11
Pages: 1093-101
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112