Type |
Details |
Score |
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
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•
•
•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
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•
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Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
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Title: |
Cyagen Biosciences Website. |
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Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
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Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
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Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
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•
•
•
•
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Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
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Title: |
Annotation inferences using phylogenetic trees |
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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•
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Publication |
First Author: |
Jamain S |
Year: |
2003 |
Journal: |
Nat Genet |
Title: |
Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism. |
Volume: |
34 |
Issue: |
1 |
Pages: |
27-9 |
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•
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HT Experiment |
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Experiment Type: |
RNA-Seq |
Study Type: |
Baseline |
Source: |
GEO |
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•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
Baseline |
Source: |
GEO |
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•
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Publication |
First Author: |
Südhof TC |
Year: |
2008 |
Journal: |
Nature |
Title: |
Neuroligins and neurexins link synaptic function to cognitive disease. |
Volume: |
455 |
Issue: |
7215 |
Pages: |
903-11 |
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•
•
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•
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Publication |
First Author: |
Craig AM |
Year: |
2007 |
Journal: |
Curr Opin Neurobiol |
Title: |
Neurexin-neuroligin signaling in synapse development. |
Volume: |
17 |
Issue: |
1 |
Pages: |
43-52 |
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Protein Domain |
Type: |
Family |
Description: |
Neuroligins (NLGNs) interact with the neurexin family members and are involved in the modulation of synaptic transmission []. Mammals have four Nlgn proteins, with the Nlgn3 and Nlgn4 gene in humans localised to the X-chromosome. In humans, the Nlgn4 gene is complemented on the Y-chromosome by a similar Nlgn5 gene []. |
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Allele |
Name: |
neuroligin 3; targeted mutation 4.1, Thomas C Sudhof |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready |
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•
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Publication |
First Author: |
Nguyen QA |
Year: |
2016 |
Journal: |
Elife |
Title: |
Distinct roles for extracellular and intracellular domains in neuroligin function at inhibitory synapses. |
Volume: |
5 |
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•
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Allele |
Name: |
neuroligin 3; targeted mutation 4, Thomas C Sudhof |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, Inserted expressed sequence, Reporter |
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Genotype |
Symbol: |
Nlgn3/? Pvalb/Pvalb<+> |
Background: |
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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•
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•
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Genotype |
Symbol: |
Nlgn3/? |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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•
•
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•
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Publication |
First Author: |
Nakanishi M |
Year: |
2017 |
Journal: |
PLoS Genet |
Title: |
Functional significance of rare neuroligin 1 variants found in autism. |
Volume: |
13 |
Issue: |
8 |
Pages: |
e1006940 |
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Strain |
Attribute String: |
congenic, mutant strain, targeted mutation |
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Genotype |
Symbol: |
Nlgn3/? Tg(Drd1-cre)EY262Gsat/? |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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•
•
•
•
•
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Genotype |
Symbol: |
Nlgn3/? Tg(Adora2a-cre)2MDkde/? |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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•
•
•
•
•
|
Genotype |
Symbol: |
Nlgn1/Nlgn1 Nlgn3/? Tg(Pcp2-cre)2Mpin/? |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6NTac |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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•
•
•
•
•
|
Genotype |
Symbol: |
Nlgn3/? Tg(Pcp2-cre)2Mpin/? |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6NTac |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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•
•
•
•
•
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Genotype |
Symbol: |
Nlgn2/Nlgn2 Nlgn3/? Tg(Pcp2-cre)2Mpin/? |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6NTac |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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•
•
•
•
•
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Genotype |
Symbol: |
Nlgn3/? Tg(Nes-cre)1Kln/? |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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•
•
•
•
•
|
Genotype |
Symbol: |
Nlgn3/? Tg(Pcp2-cre)2Mpin/? |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Nlgn3/? |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 |
Zygosity: |
ot |
Has Mutant Allele: |
true |
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•
•
•
•
•
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Publication |
First Author: |
Li ZQ |
Year: |
2018 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Suppression of NLRP3 inflammasome attenuates stress-induced depression-like behavior in NLGN3-deficient mice. |
Volume: |
501 |
Issue: |
4 |
Pages: |
933-940 |
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•
•
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•
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Genotype |
Symbol: |
Nlgn1/Nlgn1 Nlgn2/Nlgn2 Nlgn3/? Tg(Pcp2-cre)2Mpin/? |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6NTac |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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•
•
•
•
•
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
325
 |
Fragment?: |
false |
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•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
554
 |
Fragment?: |
true |
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•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
836
 |
Fragment?: |
false |
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•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
843
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
814
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
814
 |
Fragment?: |
false |
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•
•
•
•
|