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Search results 201 to 300 out of 364 for Nrf1

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Type Details Score
Publication
18599449 | J:137868
First Author: Pfluger PT
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Sirt1 protects against high-fat diet-induced metabolic damage.
Volume: 105
Issue: 28
Pages: 9793-8
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Publication
18782566 | J:141270
First Author: Prasad S
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Interaction of USF1/USF2 and alpha-Pal/Nrf1 to Fmr-1 promoter increases in mouse brain during aging.
Volume: 376
Issue: 2
Pages: 347-51
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Publication
19615412 | J:153432
First Author: Dhar SS
Year: 2009
Journal: Biochim Biophys Acta
Title: Transcriptional coupling of synaptic transmission and energy metabolism: role of nuclear respiratory factor 1 in co-regulating neuronal nitric oxide synthase and cytochrome c oxidase genes in neurons.
Volume: 1793
Issue: 10
Pages: 1604-13
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Publication
32499508 | J:294117
First Author: Robinette TM
Year: 2020
Journal: Nat Commun
Title: SIRT1 accelerates the progression of activity-based anorexia.
Volume: 11
Issue: 1
Pages: 2814
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Publication
18845810 | J:155283
First Author: Piantadosi CA
Year: 2008
Journal: Circ Res
Title: Heme oxygenase-1 regulates cardiac mitochondrial biogenesis via Nrf2-mediated transcriptional control of nuclear respiratory factor-1.
Volume: 103
Issue: 11
Pages: 1232-40
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Publication
30217595 | J:264553
First Author: Tarchini B
Year: 2018
Journal: Dev Biol
Title: A spontaneous mouse deletion in Mctp1 uncovers a long-range cis-regulatory region crucial for NR2F1 function during inner ear development.
Volume: 443
Issue: 2
Pages: 153-164
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Publication
27760051 | J:239614
First Author: Long J
Year: 2016
Journal: J Clin Invest
Title: Long noncoding RNA Tug1 regulates mitochondrial bioenergetics in diabetic nephropathy.
Volume: 126
Issue: 11
Pages: 4205-4218
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Publication
15895466 | J:99438
First Author: Thundathil J
Year: 2005
Journal: Mol Reprod Dev
Title: Molecular control of mitochondrial function in preimplantation mouse embryos.
Volume: 71
Issue: 4
Pages: 405-13
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Publication
36693621 | J:333944
 
First Author: Khadhraoui N
Year: 2023
Journal: Mol Metab
Title: Hacd2 deficiency in mice leads to an early and lethal mitochondrial disease.
Volume: 69
Pages: 101677
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Publication
27407143 | J:235155
First Author: Doucet-Beaupré H
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons.
Volume: 113
Issue: 30
Pages: E4387-96
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Publication
11940593 | J:76945
First Author: Carmona MC
Year: 2002
Journal: J Biol Chem
Title: Mitochondrial biogenesis and thyroid status maturation in brown fat require CCAAT/enhancer-binding protein alpha.
Volume: 277
Issue: 24
Pages: 21489-98
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Publication
28474670 | J:250342
 
First Author: Wang F
Year: 2017
Journal: Nat Commun
Title: Protein kinase C-alpha suppresses autophagy and induces neural tube defects via miR-129-2 in diabetic pregnancy.
Volume: 8
Pages: 15182
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Publication
23499423 | J:198125
First Author: Rajakumari S
Year: 2013
Journal: Cell Metab
Title: EBF2 determines and maintains brown adipocyte identity.
Volume: 17
Issue: 4
Pages: 562-74
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Publication
26876175 | J:301859
First Author: Poché RA
Year: 2016
Journal: Cell Rep
Title: RONIN Is an Essential Transcriptional Regulator of Genes Required for Mitochondrial Function in the Developing Retina.
Volume: 14
Issue: 7
Pages: 1684-1697
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Publication
23342106 | J:195854
First Author: Zhu Y
Year: 2013
Journal: PLoS One
Title: Mechanistic target of rapamycin (Mtor) is essential for murine embryonic heart development and growth.
Volume: 8
Issue: 1
Pages: e54221
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Publication
17276355 | J:129766
First Author: Sano M
Year: 2007
Journal: Cell Metab
Title: Ménage-à-trois 1 is critical for the transcriptional function of PPARgamma coactivator 1.
Volume: 5
Issue: 2
Pages: 129-42
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Publication
22904094 | J:212629
First Author: Papanicolaou KN
Year: 2012
Journal: Circ Res
Title: Mitofusins 1 and 2 are essential for postnatal metabolic remodeling in heart.
Volume: 111
Issue: 8
Pages: 1012-26
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Publication
30818059 | J:291414
 
First Author: Pérez-Estrada JR
Year: 2019
Journal: Free Radic Biol Med
Title: Reduced lifespan of mice lacking catalase correlates with altered lipid metabolism without oxidative damage or premature aging.
Volume: 135
Pages: 102-115
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Publication
29950673 | J:266104
First Author: Choi JH
Year: 2018
Journal: Nat Commun
Title: mTORC1 accelerates retinal development via the immunoproteasome.
Volume: 9
Issue: 1
Pages: 2502
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Publication
35293971 | J:331835
First Author: Salazar-Petres E
Year: 2022
Journal: Biol Reprod
Title: Placental structure, function, and mitochondrial phenotype relate to fetal size in each fetal sex in mice†.
Volume: 106
Issue: 6
Pages: 1292-1311
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Publication
21194568 | J:171293
First Author: Campbell GR
Year: 2011
Journal: Mol Cell Neurosci
Title: Transcription factors expressed in olfactory bulb local progenitor cells revealed by genome-wide transcriptome profiling.
Volume: 46
Issue: 2
Pages: 548-61
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Publication
32290105 | J:282558
 
First Author: Collin GB
Year: 2020
Journal: Cells
Title: Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.
Volume: 9
Issue: 4
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Publication
- | J:24194
     
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 104
Description: Transcription factor NRF1
Type: chain
End: 741
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Component
Component
Name: Transcription factor NRF1
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HT Experiment
E-GEOD-35124 | Comparison of gene expression profiles among Nrf1 liver-specific conditional knockout, Nrf2 knockout and Keap1 knockdown mice
Series Id: GSE35124
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
36248746 | J:330405
First Author: Ribeiro ST
Year: 2022
Journal: iScience
Title: The protease DDI2 regulates NRF1 activation in response to cadmium toxicity.
Volume: 25
Issue: 10
Pages: 105227
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Publication
34489413 | J:311768
First Author: Cui M
Year: 2021
Journal: Nat Commun
Title: Nrf1 promotes heart regeneration and repair by regulating proteostasis and redox balance.
Volume: 12
Issue: 1
Pages: 5270
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Publication
27528193 | J:276391
   
First Author: Koizumi S
Year: 2016
Journal: Elife
Title: The aspartyl protease DDI2 activates Nrf1 to compensate for proteasome dysfunction.
Volume: 5
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Publication
24448410 | J:283204
 
First Author: Radhakrishnan SK
Year: 2014
Journal: Elife
Title: p97-dependent retrotranslocation and proteolytic processing govern formation of active Nrf1 upon proteasome inhibition.
Volume: 3
Pages: e01856
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Publication
31931283 | J:309119
 
First Author: Xue P
Year: 2020
Journal: Redox Biol
Title: Long isoforms of NRF1 negatively regulate adipogenesis via suppression of PPARγ expression.
Volume: 30
Pages: 101414
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Publication
37501930 | J:347806
 
First Author: Trites MJ
Year: 2023
Journal: Front Physiol
Title: HDL functionality is dependent on hepatocyte stress defense factors Nrf1 and Nrf2.
Volume: 14
Pages: 1212785
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Publication
10601325 | J:276393
First Author: Kwong M
Year: 1999
Journal: J Biol Chem
Title: The CNC basic leucine zipper factor, Nrf1, is essential for cell survival in response to oxidative stress-inducing agents. Role for Nrf1 in gamma-gcs(l) and gss expression in mouse fibroblasts.
Volume: 274
Issue: 52
Pages: 37491-8
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Publication
16886907 | J:116528
First Author: Mahishi L
Year: 2006
Journal: Biochem J
Title: NF-Y, AP2, Nrf1 and Sp1 regulate the fragile X-related gene 2 (FXR2).
Volume: 400
Issue: 2
Pages: 327-35
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Publication
36989111 | J:334760
First Author: Wang X
Year: 2023
Journal: Cell Rep
Title: The N(6)-methyladenine DNA demethylase ALKBH1 promotes gastric carcinogenesis by disrupting NRF1 binding capacity.
Volume: 42
Issue: 3
Pages: 112279
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Publication
26254094 | J:254173
First Author: Bugno M
Year: 2015
Journal: Biochim Biophys Acta
Title: Changing gears in Nrf1 research, from mechanisms of regulation to its role in disease and prevention.
Volume: 1849
Issue: 10
Pages: 1260-76
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Publication
24462598 | J:212052
First Author: Song MO
Year: 2014
Journal: Exp Cell Res
Title: The role of Nrf1 and Nrf2 in the regulation of copper-responsive transcription.
Volume: 322
Issue: 1
Pages: 39-50
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Publication
37456842 | J:338390
First Author: Wei J
Year: 2023
Journal: iScience
Title: Hepatic depletion of nucleolar protein mDEF causes excessive mitochondrial copper accumulation associated with p53 and NRF1 activation.
Volume: 26
Issue: 7
Pages: 107220
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Publication
12968018 | J:86725
First Author: Leung L
Year: 2003
Journal: J Biol Chem
Title: Deficiency of the Nrf1 and Nrf2 transcription factors results in early embryonic lethality and severe oxidative stress.
Volume: 278
Issue: 48
Pages: 48021-9
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Publication
15308669 | J:251998
First Author: Narayanan K
Year: 2004
Journal: J Biol Chem
Title: The CCAAT enhancer-binding protein (C/EBP)beta and Nrf1 interact to regulate dentin sialophosphoprotein (DSPP) gene expression during odontoblast differentiation.
Volume: 279
Issue: 44
Pages: 45423-32
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Publication
15738389 | J:97188
First Author: Xu Z
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Liver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia.
Volume: 102
Issue: 11
Pages: 4120-5
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Publication
27676298 | J:297195
First Author: Sha Z
Year: 2016
Journal: Curr Biol
Title: Reply to Vangala et al.: Complete inhibition of the proteasome reduces new proteasome production by causing Nrf1 aggregation.
Volume: 26
Issue: 18
Pages: R836-R837
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Publication
24071582 | J:211415
First Author: Fischer M
Year: 2014
Journal: Nucleic Acids Res
Title: Polo-like kinase 4 transcription is activated via CRE and NRF1 elements, repressed by DREAM through CDE/CHR sites and deregulated by HPV E7 protein.
Volume: 42
Issue: 1
Pages: 163-80
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Publication
16872277 | J:116009
First Author: Zhang Y
Year: 2006
Journal: Biochem J
Title: Negative regulation of the Nrf1 transcription factor by its N-terminal domain is independent of Keap1: Nrf1, but not Nrf2, is targeted to the endoplasmic reticulum.
Volume: 399
Issue: 3
Pages: 373-85
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Publication
19665035 | -
First Author: Biswas M
Year: 2010
Journal: Toxicol Appl Pharmacol
Title: Role of Nrf1 in antioxidant response element-mediated gene expression and beyond.
Volume: 244
Issue: 1
Pages: 16-20
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Protein
Q9Z2E8
Organism: Mus musculus/domesticus
Length: 749  
Fragment?: false
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Interaction Experiment
Liu S (2021)
Description: NRF1 association with AUTS2-Polycomb mediates specific gene activation in the brain.
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Publication
25290918 | J:223104
First Author: Zhang Y
Year: 2014
Journal: PLoS One
Title: The C-terminal domain of Nrf1 negatively regulates the full-length CNC-bZIP factor and its shorter isoform LCR-F1/Nrf1β; both are also inhibited by the small dominant-negative Nrf1γ/δ isoforms that down-regulate ARE-battery gene expression.
Volume: 9
Issue: 10
Pages: e109159
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HT Experiment
GSE101550 | Essential roles of mitochondria biogenesis regulator Nrf1 in retina development and homeostasis
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Protein
Q61985
Organism: Mus musculus/domesticus
Length: 741  
Fragment?: false
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Protein Coding Gene
MGI:99421 | Nfe2l1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
9580677 | -
First Author: Prieschl EE
Year: 1998
Journal: Nucleic Acids Res
Title: A novel splice variant of the transcription factor Nrf1 interacts with the TNFalpha promoter and stimulates transcription.
Volume: 26
Issue: 10
Pages: 2291-7
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Publication
26268886 | -
 
First Author: Zhang Y
Year: 2015
Journal: Sci Rep
Title: The selective post-translational processing of transcription factor Nrf1 yields distinct isoforms that dictate its ability to differentially regulate gene expression.
Volume: 5
Pages: 12983
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Protein
Q61985-2
Organism: Mus musculus/domesticus
Length: 313  
Fragment?: false
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Protein
Q61985-3
Organism: Mus musculus/domesticus
Length: 583  
Fragment?: false
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Publication
20629635 | -
First Author: Zhang Y
Year: 2010
Journal: Biochem J
Title: Identification of topological determinants in the N-terminal domain of transcription factor Nrf1 that control its orientation in the endoplasmic reticulum membrane.
Volume: 430
Issue: 3
Pages: 497-510
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Publication
9826775 | -
First Author: Novotny V
Year: 1998
Journal: Nucleic Acids Res
Title: Nrf1 in a complex with fosB, c-jun, junD and ATF2 forms the AP1 component at the TNF alpha promoter in stimulated mast cells.
Volume: 26
Issue: 23
Pages: 5480-5
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Protein
A2A6D0
Organism: Mus musculus/domesticus
Length: 148  
Fragment?: true
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Protein
A2A6D1
Organism: Mus musculus/domesticus
Length: 152  
Fragment?: true
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Protein Domain
IPR029847 | NFE2L1
Type: Family
Description: NFE2L1 is an endoplasmic reticulum membrane sensor which, in response to various stresses, it is released from the ER membrane following cleavage by the protease DDI2 and translocates into the nucleus to form the transcription factor NRF1 []. In conditions of excess cholesterol, the endoplasmic reticulum membrane form of the protein directly binds cholesterol via its CRAC motif, preventing cleavage and release of the transcription factor NRF1, this allows the expression of genes promoting cholesterol removal []. In response to oxidative stress, Nrf1 up-regulates expression of antioxidant genes by binding to the antioxidant response elements (AREs) present in the promoter of these genes []. In humans Nrf1 exists in two forms, p120 and p110. p120 is embedded in the ER membrane, while p110 is soluble and can enter the nucleus [, ].
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Publication
17014843 | -
First Author: Du X
Year: 2006
Journal: Exp Mol Pathol
Title: DIPA, which can localize to the centrosome, associates with p78/MCRS1/MSP58 and acts as a repressor of gene transcription.
Volume: 81
Issue: 3
Pages: 184-90
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Publication
19187526 | -
 
First Author: Wu JL
Year: 2009
Journal: BMC Cell Biol
Title: MCRS2 represses the transactivation activities of Nrf1.
Volume: 10
Pages: 9
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