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Search results 201 to 259 out of 259 for Nxf2

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:5648881
Assay Type: RNA in situ
Annotation Date: 2015-08-18
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1606611
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:5648954
Age: embryonic day 7.5
Image: 2F
Specimen Label: 2F
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:5648881
Assay Type: RNA in situ
Annotation Date: 2015-08-18
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1604220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5648954
Age: embryonic day 12.5
Image: 2H
Note: Expression is present in the allantois.
Specimen Label: 2H
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:5648881
Assay Type: RNA in situ
Annotation Date: 2015-08-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649064
Age: postnatal adult
Image: 3A
Note: Expression is more intense in this layer.
Specimen Label: 3A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5648913
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5649071
Age: postnatal week 6
Image: Cx WT
Specimen Label: Cx WT
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5648913
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-19
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3525928
Stage: TS28
Assay Id: MGI:5649071
Age: postnatal week 6
Image: Cx KO
Specimen Label: Cx KO
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:5648881
Assay Type: RNA in situ
Annotation Date: 2015-08-18
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3187713
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:5648954
Age: embryonic day 8.5
Image: 2G
Specimen Label: 2G
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:5648881
Assay Type: RNA in situ
Annotation Date: 2015-08-18
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1611211
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:5648954
Age: embryonic day 7.5
Image: 2F
Specimen Label: 2F
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:5648881
Assay Type: RNA in situ
Annotation Date: 2015-08-18
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5648954
Age: postnatal adult
Image: 2I
Specimen Label: 2I
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:5648881
Assay Type: RNA in situ
Annotation Date: 2015-08-18
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1610711
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:5648954
Age: embryonic day 7.5
Image: 2D
Specimen Label: 2D
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5648881
Assay Type: RNA in situ
Annotation Date: 2015-08-18
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1610713
Pattern: Not Specified
Stage: TS13
Assay Id: MGI:5648954
Age: embryonic day 8.5
Image: 2E
Specimen Label: 2E
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5648881
Assay Type: RNA in situ
Annotation Date: 2015-08-18
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1610711
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:5648954
Age: embryonic day 7.5
Image: 2F
Specimen Label: 2F
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3615800
Assay Type: RNA in situ
Annotation Date: 2006-03-28
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1679727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3618067
Age: postnatal day 0
Image: P0
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: P0
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3615800
Assay Type: RNA in situ
Annotation Date: 2006-03-28
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754027
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3618067
Age: postnatal day 0
Image: P0
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: P0
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3615800
Assay Type: RNA in situ
Annotation Date: 2006-03-28
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3280927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3618067
Age: postnatal day 0
Image: P0
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: P0
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3615800
Assay Type: RNA in situ
Annotation Date: 2006-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267921
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3618067
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3615800
Assay Type: RNA in situ
Annotation Date: 2006-03-28
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1757721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3618067
Age: embryonic day 13.5
Image: E13.5
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: E13.5
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3615800
Assay Type: RNA in situ
Annotation Date: 2006-03-28
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1757727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3618067
Age: postnatal day 0
Image: P0
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: P0
Specimen Num: 2
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Publication
11583626 | -
First Author: Fribourg S
Year: 2001
Journal: Mol Cell
Title: Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor.
Volume: 8
Issue: 3
Pages: 645-56
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Publication
9660949 | -
First Author: Grüter P
Year: 1998
Journal: Mol Cell
Title: TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleus.
Volume: 1
Issue: 5
Pages: 649-59
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Publication
10668806 | -
First Author: Bachi A
Year: 2000
Journal: RNA
Title: The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates.
Volume: 6
Issue: 1
Pages: 136-58
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HT Experiment
E-GEOD-29541 | Mice with targeted deletion of Nxf7, the murine ortholog of the clinically implicated NXF5, display impaired hippocampal learning and neuroplasticity
Series Id: GSE29541
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Protein
A2AEI5
Organism: Mus musculus/domesticus
Length: 127  
Fragment?: true
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Publication
11545741 | -
First Author: Yang J
Year: 2001
Journal: Mol Cell
Title: Two closely related human nuclear export factors utilize entirely distinct export pathways.
Volume: 8
Issue: 2
Pages: 397-406
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Publication
24569167 | J:210663
First Author: Zhou J
Year: 2014
Journal: Hum Mol Genet
Title: Respiratory failure, cleft palate and epilepsy in the mouse model of human Xq22.1 deletion syndrome.
Volume: 23
Issue: 14
Pages: 3823-9
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Publication
35192609 | J:322528
First Author: Agrimson KS
Year: 2022
Journal: PLoS Genet
Title: Lrh1 can help reprogram sexual cell fate and is required for Sertoli cell development and spermatogenesis in the mouse testis.
Volume: 18
Issue: 2
Pages: e1010088
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Protein
V9GXM5
Organism: Mus musculus/domesticus
Length: 89  
Fragment?: true
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Publication
10567585 | J:66319
First Author: Black BE
Year: 1999
Journal: Mol Cell Biol
Title: Identification of an NTF2-related factor that binds Ran-GTP and regulates nuclear protein export.
Volume: 19
Issue: 12
Pages: 8616-24
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Publication
11875519 | -
First Author: Grant RP
Year: 2002
Journal: Nat Struct Biol
Title: Structure of the C-terminal FG-nucleoporin binding domain of Tap/NXF1.
Volume: 9
Issue: 4
Pages: 247-51
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Publication
11060011 | -
First Author: Liker E
Year: 2000
Journal: EMBO J
Title: The structure of the mRNA export factor TAP reveals a cis arrangement of a non-canonical RNP domain and an LRR domain.
Volume: 19
Issue: 21
Pages: 5587-98
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Publication
11256625 | -
First Author: Suyama M
Year: 2000
Journal: EMBO Rep
Title: Prediction of structural domains of TAP reveals details of its interaction with p15 and nucleoporins.
Volume: 1
Issue: 1
Pages: 53-8
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Publication
19401465 | -
First Author: Hobeika M
Year: 2009
Journal: J Biol Chem
Title: Structural requirements for the ubiquitin-associated domain of the mRNA export factor Mex67 to bind its specific targets, the transcription elongation THO complex component Hpr1 and nucleoporin FXFG repeats.
Volume: 284
Issue: 26
Pages: 17575-83
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Publication
11259411 | -
First Author: Braun IC
Year: 2001
Journal: J Biol Chem
Title: Overexpression of TAP/p15 heterodimers bypasses nuclear retention and stimulates nuclear mRNA export.
Volume: 276
Issue: 23
Pages: 20536-43
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Publication
9175835 | -
First Author: Yoon DW
Year: 1997
Journal: Immunity
Title: Tap: a novel cellular protein that interacts with tip of herpesvirus saimiri and induces lymphocyte aggregation.
Volume: 6
Issue: 5
Pages: 571-82
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Publication
10454577 | J:56952
First Author: Bear J
Year: 1999
Journal: Mol Cell Biol
Title: Identification of novel import and export signals of human TAP, the protein that binds to the constitutive transport element of the type D retrovirus mRNAs.
Volume: 19
Issue: 9
Pages: 6306-17
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Publication
10323864 | -
First Author: Kang Y
Year: 1999
Journal: Genes Dev
Title: The human Tap protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequences.
Volume: 13
Issue: 9
Pages: 1126-39
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Publication
10202158 | J:54353
First Author: Braun IC
Year: 1999
Journal: EMBO J
Title: TAP binds to the constitutive transport element (CTE) through a novel RNA-binding motif that is sufficient to promote CTE-dependent RNA export from the nucleus.
Volume: 18
Issue: 7
Pages: 1953-65
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Protein Domain
IPR005637 | TAP_C_dom
Type: Domain
Description: The vertebrate Tap protein is a member of the NXF family of shuttling transport receptors for nuclear export of mRNA. Tap has a modular structure, and its most C-terminal domain is important for binding to FG repeat-containing nuclear pore proteins (FG-nucleoporins) and is sufficient to mediate nuclear shuttling []. The structure of the C-terminal domain is composed of four helices []. The structure is related to the UBA domain.The NXF family of mRNA nuclear export factors includes vertebrate NXF1 (also called tip-associated protein or mRNA export factor TAP), NXF2 (also called cancer/testis antigen CT39 or TAP-like protein TAPL-2), Caenorhabditis elegans NXF1 (ceNXF1), Saccharomyces cerevisiae mRNA nuclear export factor Mex67p and similar proteins. NXF proteins can stimulate nuclear export of mRNAs and facilitate the export of unspliced viral mRNA containing the constitutive transport element. An NXF protein is multi-domain with a nuclear localization sequence (NLS), a non-canonical mRNA-binding domain, and four leucine-rich repeats (LLR) at the N-terminal region. Its C-terminal part contains a NTF2-like domain and a ubiquitin-associated (UBA)-like domain, joined by flexible Pro-rich linker. Caenorhabditis elegans NXF1 are essential for the nuclear export of poly(A)+mRNA. In budding yeast, Mex67p binds mRNAs through its adaptor Yra1/REF. It also interacts directly with Nab2, an essential shuttling mRNA-binding protein required for export. Moreover, Mex67p associates with both nuclear pore protein (nucleoporin) FG repeats and Hpr1, a component of the TREX/THO complex linking transcription and export [, , , , , , , , , , , , , , , ].
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Protein
A2AEI4
Organism: Mus musculus/domesticus
Length: 155  
Fragment?: true
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Protein
B1AUS0
Organism: Mus musculus/domesticus
Length: 103  
Fragment?: true
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Protein
Q99JG4
Organism: Mus musculus/domesticus
Length: 187  
Fragment?: true
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Publication
11073998 | -
First Author: Herold A
Year: 2000
Journal: Mol Cell Biol
Title: TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture.
Volume: 20
Issue: 23
Pages: 8996-9008
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Publication
12581645 | -
First Author: Grant RP
Year: 2003
Journal: J Mol Biol
Title: Structural basis for the interaction between the Tap/NXF1 UBA domain and FG nucleoporins at 1A resolution.
Volume: 326
Issue: 3
Pages: 849-58
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Publication
20810649 | -
First Author: Iglesias N
Year: 2010
Journal: Genes Dev
Title: Ubiquitin-mediated mRNP dynamics and surveillance prior to budding yeast mRNA export.
Volume: 24
Issue: 17
Pages: 1927-38
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Protein
V9GXW3
Organism: Mus musculus/domesticus
Length: 282  
Fragment?: false
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Protein
V9GXF3
Organism: Mus musculus/domesticus
Length: 418  
Fragment?: false
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Protein
Q99JX7
Organism: Mus musculus/domesticus
Length: 618  
Fragment?: false
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Protein
Q4ZGD9
Organism: Mus musculus/domesticus
Length: 553  
Fragment?: false
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Protein
Q99JG6
Organism: Mus musculus/domesticus
Length: 473  
Fragment?: true
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Protein
Q8BP60
Organism: Mus musculus/domesticus
Length: 618  
Fragment?: false
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Protein
F7AR15
Organism: Mus musculus/domesticus
Length: 475  
Fragment?: true
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Protein
Q99MW6
Organism: Mus musculus/domesticus
Length: 685  
Fragment?: false
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Protein
Q8R499
Organism: Mus musculus/domesticus
Length: 671  
Fragment?: false
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Protein
Q99JG5
Organism: Mus musculus/domesticus
Length: 509  
Fragment?: true
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Protein
Q80SZ6
Organism: Mus musculus/domesticus
Length: 620  
Fragment?: false
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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