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Search results 201 to 300 out of 354 for Opa1

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Type Details Score
GXD Expression    
Probe: MGI:3770633
Assay Type: Immunohistochemistry
Annotation Date: 2008-02-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573928
Pattern: Diffuse
Stage: TS28
Assay Id: MGI:3770640
Age: postnatal day 4
Specimen Label: 3D
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:3770633
Assay Type: Immunohistochemistry
Annotation Date: 2008-02-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3770640
Age: postnatal day 8
Specimen Label: 3F
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:3770633
Assay Type: Immunohistochemistry
Annotation Date: 2008-02-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3770640
Age: postnatal day 12
Specimen Label: 3G
Detected: true
Specimen Num: 15
GXD Expression    
Probe: MGI:3770633
Assay Type: Immunohistochemistry
Annotation Date: 2008-02-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3573928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3770640
Age: postnatal adult
Specimen Label: 4B
Detected: true
Specimen Num: 16
GXD Expression    
Probe: MGI:3770633
Assay Type: Immunohistochemistry
Annotation Date: 2008-02-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3573928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3770640
Age: postnatal adult
Specimen Label: 4D
Detected: true
Specimen Num: 18
GXD Expression    
Probe: MGI:3770633
Assay Type: Immunohistochemistry
Annotation Date: 2008-02-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3573928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3770640
Age: postnatal adult
Specimen Label: 4E
Detected: true
Specimen Num: 20
GXD Expression    
Probe: MGI:3770633
Assay Type: Immunohistochemistry
Annotation Date: 2008-02-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752525
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:3770640
Age: embryonic day 17.5
Specimen Label: Not shown
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:3770633
Assay Type: Immunohistochemistry
Annotation Date: 2008-02-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3770640
Age: postnatal day 1
Specimen Label: 3B
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:3770633
Assay Type: Immunohistochemistry
Annotation Date: 2008-02-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3770640
Age: postnatal day 4
Specimen Label: 3E
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:3770633
Assay Type: Immunohistochemistry
Annotation Date: 2008-02-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1757528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3770640
Age: postnatal adult
Note: Weak, patchy expression is observed in the myelinated region.
Specimen Label: 4F
Detected: true
Specimen Num: 21
GXD Expression    
Probe: MGI:3770633
Assay Type: Immunohistochemistry
Annotation Date: 2008-02-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3770640
Age: embryonic day 16.5
Specimen Label: Not shown
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:3770633
Assay Type: Immunohistochemistry
Annotation Date: 2008-02-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689425
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:3770640
Age: embryonic day 17.5
Specimen Label: Not shown
Detected: true
Specimen Num: 8
Publication
First Author: Ramírez S
Year: 2017
Journal: Cell Metab
Title: Mitochondrial Dynamics Mediated by Mitofusin 1 Is Required for POMC Neuron Glucose-Sensing and Insulin Release Control.
Volume: 25
Issue: 6
Pages: 1390-1399.e6
Publication
First Author: García-García MJ
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Analysis of mouse embryonic patterning and morphogenesis by forward genetics.
Volume: 102
Issue: 17
Pages: 5913-9
Publication
First Author: Patterson VL
Year: 2014
Journal: PLoS One
Title: Neural-specific deletion of Htra2 causes cerebellar neurodegeneration and defective processing of mitochondrial OPA1.
Volume: 9
Issue: 12
Pages: e115789
Publication  
First Author: Beirne K
Year: 2021
Journal: Int J Mol Sci
Title: Red Light Irradiation In Vivo Upregulates DJ-1 in the Retinal Ganglion Cell Layer and Protects against Axotomy-Related Dendritic Pruning.
Volume: 22
Issue: 16
Publication  
First Author: Khacho M
Year: 2014
Journal: Nat Commun
Title: Acidosis overrides oxygen deprivation to maintain mitochondrial function and cell survival.
Volume: 5
Pages: 3550
Publication
First Author: Fogo GM
Year: 2021
Journal: Sci Rep
Title: Machine learning-based classification of mitochondrial morphology in primary neurons and brain.
Volume: 11
Issue: 1
Pages: 5133
Publication
First Author: Stavru F
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Atypical mitochondrial fission upon bacterial infection.
Volume: 110
Issue: 40
Pages: 16003-8
Publication
First Author: Li J
Year: 2019
Journal: Int J Biol Sci
Title: Amorphous solid dispersion of Berberine mitigates apoptosis via iPLA2β/Cardiolipin/Opa1 pathway in db/db mice and in Palmitate-treated MIN6 β-cells.
Volume: 15
Issue: 7
Pages: 1533-1545
Publication
First Author: Favaro G
Year: 2019
Journal: Nat Commun
Title: DRP1-mediated mitochondrial shape controls calcium homeostasis and muscle mass.
Volume: 10
Issue: 1
Pages: 2576
Publication
First Author: Field CS
Year: 2020
Journal: Cell Metab
Title: Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function.
Volume: 31
Issue: 2
Pages: 422-437.e5
Publication
First Author: Garedew A
Year: 2012
Journal: Cell Metab
Title: Mitochondrial dynamics, biogenesis, and function are coordinated with the cell cycle by APC/C CDH1.
Volume: 15
Issue: 4
Pages: 466-79
Publication
First Author: Karbowski M
Year: 2006
Journal: Nature
Title: Role of Bax and Bak in mitochondrial morphogenesis.
Volume: 443
Issue: 7112
Pages: 658-62
Publication
First Author: Kenny TC
Year: 2023
Journal: Cell Metab
Title: Integrative genetic analysis identifies FLVCR1 as a plasma-membrane choline transporter in mammals.
Volume: 35
Issue: 6
Pages: 1057-1071.e12
Publication
First Author: Yamada T
Year: 2018
Journal: Cell Metab
Title: Mitochondrial Stasis Reveals p62-Mediated Ubiquitination in Parkin-Independent Mitophagy and Mitigates Nonalcoholic Fatty Liver Disease.
Volume: 28
Issue: 4
Pages: 588-604.e5
Publication
First Author: Rochais F
Year: 2009
Journal: PLoS One
Title: Hes1 is expressed in the second heart field and is required for outflow tract development.
Volume: 4
Issue: 7
Pages: e6267
Publication
First Author: Perico L
Year: 2021
Journal: Sci Rep
Title: Post-translational modifications by SIRT3 de-2-hydroxyisobutyrylase activity regulate glycolysis and enable nephrogenesis.
Volume: 11
Issue: 1
Pages: 23580
Publication  
First Author: Raynor JL
Year: 2020
Journal: J Exp Med
Title: Hippo/Mst signaling coordinates cellular quiescence with terminal maturation in iNKT cell development and fate decisions.
Volume: 217
Issue: 6
Publication
First Author: Ishihara N
Year: 2009
Journal: Nat Cell Biol
Title: Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice.
Volume: 11
Issue: 8
Pages: 958-66
Publication
First Author: Moriya M
Year: 2015
Journal: Hum Mol Genet
Title: Adult mice expressing a Braf Q241R mutation on an ICR/CD-1 background exhibit a cardio-facio-cutaneous syndrome phenotype.
Volume: 24
Issue: 25
Pages: 7349-60
Publication
First Author: Augustin M
Year: 2005
Journal: Mamm Genome
Title: Efficient and fast targeted production of murine models based on ENU mutagenesis.
Volume: 16
Issue: 6
Pages: 405-13
Publication  
First Author: Ha HT
Year: 2024
Journal: JCI Insight
Title: Lack of SPNS1 results in accumulation of lysolipids and lysosomal storage disease in mouse models.
Volume: 9
Issue: 8
Publication
First Author: Marta C
Year: 2022
Journal: Sci Rep
Title: Mitochondrial function and intracellular distribution is severely affected in in vitro cultured mouse embryos.
Volume: 12
Issue: 1
Pages: 16152
Publication
First Author: Wang D
Year: 2023
Journal: Nat Commun
Title: MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters.
Volume: 14
Issue: 1
Pages: 4404
Publication
First Author: Schatton D
Year: 2017
Journal: J Cell Biol
Title: CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs.
Volume: 216
Issue: 3
Pages: 675-693
Publication
First Author: Fakruddin M
Year: 2018
Journal: Cell Rep
Title: Defective Mitochondrial tRNA Taurine Modification Activates Global Proteostress and Leads to Mitochondrial Disease.
Volume: 22
Issue: 2
Pages: 482-496
Publication  
First Author: Mirra S
Year: 2021
Journal: Neurobiol Dis
Title: CERKL, a retinal dystrophy gene, regulates mitochondrial function and dynamics in the mammalian retina.
Volume: 156
Pages: 105405
Publication  
First Author: Shen T
Year: 2024
Journal: Biochem Biophys Res Commun
Title: Cardiac-specific deletion of heat shock protein 60 induces mitochondrial stress and disrupts heart development in mice.
Volume: 710
Pages: 149883
Publication
First Author: Menendez-Montes I
Year: 2016
Journal: Dev Cell
Title: Myocardial VHL-HIF Signaling Controls an Embryonic Metabolic Switch Essential for Cardiac Maturation.
Volume: 39
Issue: 6
Pages: 724-739
Publication
First Author: Kiyama T
Year: 2018
Journal: Mol Neurodegener
Title: Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis.
Volume: 13
Issue: 1
Pages: 56
Publication
First Author: Salazar-Petres E
Year: 2022
Journal: Biol Reprod
Title: Placental structure, function, and mitochondrial phenotype relate to fetal size in each fetal sex in mice†.
Volume: 106
Issue: 6
Pages: 1292-1311
Publication
First Author: Da Cruz S
Year: 2003
Journal: J Biol Chem
Title: Proteomic analysis of the mouse liver mitochondrial inner membrane.
Volume: 278
Issue: 42
Pages: 41566-71
Publication
First Author: Mootha VK
Year: 2003
Journal: Cell
Title: Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Volume: 115
Issue: 5
Pages: 629-40
Publication
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication  
First Author: Sanderson TH
Year: 2015
Journal: Mol Cell Neurosci
Title: Release of mitochondrial Opa1 following oxidative stress in HT22 cells.
Volume: 64
Pages: 116-22
Publication  
First Author: Cartes-Saavedra B
Year: 2021
Journal: Front Cell Dev Biol
Title: OPA1 Modulates Mitochondrial Ca2+ Uptake Through ER-Mitochondria Coupling.
Volume: 9
Pages: 774108
Publication  
First Author: Hering T
Year: 2017
Journal: Exp Neurol
Title: Mitochondrial cristae remodelling is associated with disrupted OPA1 oligomerisation in the Huntington's disease R6/2 fragment model.
Volume: 288
Pages: 167-175
Publication
First Author: Li L
Year: 2019
Journal: J Biol Chem
Title: In vivo stabilization of OPA1 in hepatocytes potentiates mitochondrial respiration and gluconeogenesis in a prohibitin-dependent way.
Volume: 294
Issue: 34
Pages: 12581-12598
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: Song Z
Year: 2007
Journal: J Cell Biol
Title: OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L.
Volume: 178
Issue: 5
Pages: 749-55
Publication
First Author: Samant SA
Year: 2014
Journal: Mol Cell Biol
Title: SIRT3 deacetylates and activates OPA1 to regulate mitochondrial dynamics during stress.
Volume: 34
Issue: 5
Pages: 807-19
Allele
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Luca Scorrano
Allele Type: Targeted
Attribute String: Inserted expressed sequence
DO Term
DO Term
Publication
First Author: Triolo M
Year: 2024
Journal: iScience
Title: Optic atrophy 1 mediates muscle differentiation by promoting a metabolic switch via the supercomplex assembly factor SCAF1.
Volume: 27
Issue: 3
Pages: 109164
Genotype
Symbol: Hprt1/?
Background: involves: 129 * C57BL/6 * C57BL/6J
Zygosity: ot
Has Mutant Allele: true
DO Term
Allele  
Name: OPA1, mitochondrial dynamin like GTPase; lilr3
Allele Type: Chemically induced (ENU)