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Search results 201 to 269 out of 269 for Osm

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Type Details Score
Protein
Q3U1H5
Organism: Mus musculus/domesticus
Length: 203  
Fragment?: false
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Publication
25921393 | J:223806
First Author: Janssens K
Year: 2015
Journal: Glia
Title: Oncostatin M protects against demyelination by inducing a protective microglial phenotype.
Volume: 63
Issue: 10
Pages: 1729-37
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Publication
32071226 | J:285755
First Author: Houben E
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Oncostatin M-induced astrocytic tissue inhibitor of metalloproteinases-1 drives remyelination.
Volume: 117
Issue: 9
Pages: 5028-5038
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Publication
33581044 | J:305831
First Author: Deerhake ME
Year: 2021
Journal: Immunity
Title: Dectin-1 limits autoimmune neuroinflammation and promotes myeloid cell-astrocyte crosstalk via Card9-independent expression of Oncostatin M.
Volume: 54
Issue: 3
Pages: 484-498.e8
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Publication
10717675 | J:61361
First Author: Harteneck C
Year: 2000
Journal: Trends Neurosci
Title: From worm to man: three subfamilies of TRP channels.
Volume: 23
Issue: 4
Pages: 159-66
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Publication
1542794 | J:35072
First Author: Gearing DP
Year: 1992
Journal: Science
Title: The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor.
Volume: 255
Issue: 5050
Pages: 1434-7
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Publication
12049776 | J:77315
First Author: Tamura S
Year: 2002
Journal: Mech Dev
Title: Developmental expression pattern of oncostatin M receptor beta in mice.
Volume: 115
Issue: 1-2
Pages: 127-31
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Protein
F8WI55
Organism: Mus musculus/domesticus
Length: 149  
Fragment?: false
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Publication
20229348 | -
First Author: Wang Y
Year: 1999
Journal: Sci China C Life Sci
Title: cDNA cloning and expression of an apoptosis-related gene, humanTFAR15 gene.
Volume: 42
Issue: 3
Pages: 323-9
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Protein Domain
IPR009652 | PDCD10
Type: Family
Description: Programmed cell death 10 protein (PDCD10/CCM3) is part of the CCM complex and is required for neuronal migration []. It also has roles outside of this complex [], it is crucial in vascularization and in angiogenesis as it functions in vessel permeability and stability []. PDCD10/CCM3 was originally discovered to be upregulated during granulocyte apoptosis and is thought to play a role in cell death []. However, a specific role for PDCD10 in cell survival is not clear as both pro-survival and pro-apoptotic effects have been reported [, ]. PDCD10/CCM3 contains an N-terminal dimerisation domain and a C-terminal focal adhesion targeting-homology (FAT-H) domain [].There are three CCM proteins: CCM1 (also known as KRIT1), CCM2 (also known as OSM and malcavernin) and CCM3 (also known as PDCD10). Mutations in the genes encoding CCM proteins cause cerebral cavernous malformations (CCMs), a disease characterised by dilated leaky blood vessels, especially in the neurovasculature, that result in increased risk of stroke, focal neurological defects and seizures. The CCM proteins can form a trimeric complex. They can also interact with a range of signaling, cytoskeletal and adaptor proteins that may account for their roles in a range of basic cellular processes including cell adhesion, migration, polarity and apoptosis [].
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Protein Coding Gene
MGI:1330819 | Osmr
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
9584176 | J:47670
First Author: Lindberg RA
Year: 1998
Journal: Mol Cell Biol
Title: Cloning and characterization of a specific receptor for mouse oncostatin M.
Volume: 18
Issue: 6
Pages: 3357-67
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Publication
10455148 | J:57022
First Author: Nakayama K
Year: 1999
Journal: J Biol Chem
Title: A novel oncostatin M-inducible gene OIG37 forms a gene family with MyD118 and GADD45 and negatively regulates cell growth.
Volume: 274
Issue: 35
Pages: 24766-72
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Publication
18981146 | J:141077
First Author: Mozaffarian A
Year: 2008
Journal: J Immunol
Title: Mechanisms of oncostatin M-induced pulmonary inflammation and fibrosis.
Volume: 181
Issue: 10
Pages: 7243-53
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Publication
24695736 | J:214124
First Author: Komori T
Year: 2014
Journal: J Biol Chem
Title: Deficiency of oncostatin M receptor β (OSMRβ) exacerbates high-fat diet-induced obesity and related metabolic disorders in mice.
Volume: 289
Issue: 20
Pages: 13821-37
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Publication
16410783 | J:106761
First Author: Goren I
Year: 2006
Journal: J Invest Dermatol
Title: Oncostatin M expression is functionally connected to neutrophils in the early inflammatory phase of skin repair: implications for normal and diabetes-impaired wounds.
Volume: 126
Issue: 3
Pages: 628-37
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Publication
34301760 | J:310829
First Author: Nguyen-Tran HH
Year: 2021
Journal: Cancer Res
Title: Endothelial Reprogramming Stimulated by Oncostatin M Promotes Inflammation and Tumorigenesis in VHL-Deficient Kidney Tissue.
Volume: 81
Issue: 19
Pages: 5060-5073
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Publication
18641356 | J:139227
First Author: Hams E
Year: 2008
Journal: J Immunol
Title: Oncostatin M receptor-beta signaling limits monocytic cell recruitment in acute inflammation.
Volume: 181
Issue: 3
Pages: 2174-80
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Publication
14999682 | J:105527
First Author: Nakamura K
Year: 2004
Journal: Hepatology
Title: Hepatocyte proliferation and tissue remodeling is impaired after liver injury in oncostatin M receptor knockout mice.
Volume: 39
Issue: 3
Pages: 635-44
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Publication
23760954 | J:198637
First Author: Minchin JE
Year: 2013
Journal: Development
Title: Oesophageal and sternohyal muscle fibres are novel Pax3-dependent migratory somite derivatives essential for ingestion.
Volume: 140
Issue: 14
Pages: 2972-84
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Publication
12891556 | J:98441
First Author: Streetz KL
Year: 2003
Journal: Gastroenterology
Title: Lack of gp130 expression in hepatocytes promotes liver injury.
Volume: 125
Issue: 2
Pages: 532-43
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Publication
37028770 | J:359907
First Author: Han H
Year: 2023
Journal: Gastroenterology
Title: Macrophage-derived Osteopontin (SPP1) Protects From Nonalcoholic Steatohepatitis.
Volume: 165
Issue: 1
Pages: 201-217
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Publication
38000729 | J:352183
 
First Author: Schwartz LS
Year: 2024
Journal: Exp Hematol
Title: Transcriptional and functional consequences of Oncostatin M signaling on young Dnmt3a-mutant hematopoietic stem cells.
Volume: 130
Pages: 104131
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Publication
12855584 | J:86261
First Author: Tanaka M
Year: 2003
Journal: Blood
Title: Targeted disruption of oncostatin M receptor results in altered hematopoiesis.
Volume: 102
Issue: 9
Pages: 3154-62
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Publication
33051515 | J:299046
First Author: Yamashita S
Year: 2020
Journal: Sci Rep
Title: Essential roles of oncostatin M receptor β signaling in renal crystal formation in mice.
Volume: 10
Issue: 1
Pages: 17150
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Publication
37120549 | J:336118
First Author: Feng Y
Year: 2023
Journal: J Transl Med
Title: OSMR deficiency aggravates pressure overload-induced cardiac hypertrophy by modulating macrophages and OSM/LIFR/STAT3 signalling.
Volume: 21
Issue: 1
Pages: 290
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Publication
23760275 | J:201766
First Author: Komori T
Year: 2013
Journal: J Biol Chem
Title: Lack of oncostatin M receptor β leads to adipose tissue inflammation and insulin resistance by switching macrophage phenotype.
Volume: 288
Issue: 30
Pages: 21861-75
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Publication
25751817 | J:227930
First Author: Lörchner H
Year: 2015
Journal: Nat Med
Title: Myocardial healing requires Reg3β-dependent accumulation of macrophages in the ischemic heart.
Volume: 21
Issue: 4
Pages: 353-62
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Publication
28258089 | J:241513
First Author: Zhang X
Year: 2017
Journal: J Lipid Res
Title: Oncostatin M receptor β deficiency attenuates atherogenesis by inhibiting JAK2/STAT3 signaling in macrophages.
Volume: 58
Issue: 5
Pages: 895-906
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Publication
38102969 | J:355493
First Author: Komori T
Year: 2024
Journal: FASEB J
Title: Blockade of OSMRβ signaling ameliorates skin lesions in a mouse model of human atopic dermatitis.
Volume: 38
Issue: 1
Pages: e23359
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Publication
20956341 | J:165780
First Author: Bilsborough J
Year: 2010
Journal: J Immunol
Title: IL-31 receptor (IL-31RA) knockout mice exhibit elevated responsiveness to oncostatin M.
Volume: 185
Issue: 10
Pages: 6023-30
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Publication
12147685 | J:79290
First Author: Matsui T
Year: 2002
Journal: J Biol Chem
Title: STAT3 down-regulates the expression of cyclin D during liver development.
Volume: 277
Issue: 39
Pages: 36167-73
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Publication
12831858 | J:84736
First Author: Tamura S
Year: 2003
Journal: Neuroscience
Title: Localization of oncostatin M receptor beta in adult and developing CNS.
Volume: 119
Issue: 4
Pages: 991-7
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Publication
15349890 | J:94930
First Author: Kamiya A
Year: 2004
Journal: Hepatology
Title: TNF-alpha regulates mouse fetal hepatic maturation induced by oncostatin M and extracellular matrices.
Volume: 40
Issue: 3
Pages: 527-36
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Publication
15893881 | J:104249
First Author: Tamura S
Year: 2005
Journal: Neuroscience
Title: Up-regulated phosphorylation of signal transducer and activator of transcription 3 and cyclic AMP-responsive element binding protein by peripheral inflammation in primary afferent neurons possibly through oncostatin M receptor.
Volume: 133
Issue: 3
Pages: 797-806
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Publication
16291739 | J:110314
First Author: Dekanty A
Year: 2006
Journal: J Biol Chem
Title: Leukemia inhibitory factor induces DNA synthesis in Swiss mouse 3T3 cells independently of cyclin D1 expression through a mechanism involving MEK/ERK1/2 activation.
Volume: 281
Issue: 10
Pages: 6136-43
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Publication
11867530 | J:115358
First Author: Matsui T
Year: 2002
Journal: EMBO J
Title: K-Ras mediates cytokine-induced formation of E-cadherin-based adherens junctions during liver development.
Volume: 21
Issue: 5
Pages: 1021-30
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Publication
17214902 | J:119912
 
First Author: Fong B
Year: 2007
Journal: BMC Dev Biol
Title: Mouse preimplantation embryo responses to culture medium osmolarity include increased expression of CCM2 and p38 MAPK activation.
Volume: 7
Pages: 2
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Publication
21457934 | J:171268
First Author: Hoermann G
Year: 2011
Journal: Am J Pathol
Title: Identification of oncostatin M as a STAT5-dependent mediator of bone marrow remodeling in KIT D816V-positive systemic mastocytosis.
Volume: 178
Issue: 5
Pages: 2344-56
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Publication
21712438 | J:174387
First Author: Zhou X
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Rac1/osmosensing scaffold for MEKK3 contributes via phospholipase C-gamma1 to activation of the osmoprotective transcription factor NFAT5.
Volume: 108
Issue: 29
Pages: 12155-60
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Publication
22051730 | J:180613
First Author: Hoermann G
Year: 2012
Journal: FASEB J
Title: Identification of oncostatin M as a JAK2 V617F-dependent amplifier of cytokine production and bone marrow remodeling in myeloproliferative neoplasms.
Volume: 26
Issue: 2
Pages: 894-906
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Publication
34408010 | J:322337
First Author: Fraszczak J
Year: 2021
Journal: J Immunol
Title: Severe Inflammatory Reactions in Mice Expressing a GFI1P2A Mutant Defective in Binding to the Histone Demethylase KDM1A (LSD1).
Volume: 207
Issue: 6
Pages: 1599-1615
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Publication
34518644 | J:319704
First Author: Bisht K
Year: 2022
Journal: Leukemia
Title: Oncostatin M regulates hematopoietic stem cell (HSC) niches in the bone marrow to restrict HSC mobilization.
Volume: 36
Issue: 2
Pages: 333-347
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Publication
34757808 | J:344047
First Author: Tseng PY
Year: 2021
Journal: Sci Transl Med
Title: Oncostatin M can sensitize sensory neurons in inflammatory pruritus.
Volume: 13
Issue: 619
Pages: eabe3037
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Protein Coding Gene
MGI:96788 | Lifr
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q8VE70
Organism: Mus musculus/domesticus
Length: 212  
Fragment?: false
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Protein
Q3TVB4
Organism: Mus musculus/domesticus
Length: 162  
Fragment?: true
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Protein
E0CY82
Organism: Mus musculus/domesticus
Length: 66  
Fragment?: true
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Publication
24595293 | J:208651
First Author: Louvi A
Year: 2014
Journal: Development
Title: Ccm3, a gene associated with cerebral cavernous malformations, is required for neuronal migration.
Volume: 141
Issue: 6
Pages: 1404-15
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Publication
24481819 | -
First Author: Draheim KM
Year: 2014
Journal: J Cell Sci
Title: Cerebral cavernous malformation proteins at a glance.
Volume: 127
Issue: Pt 4
Pages: 701-7
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Publication
26490252 | -
 
First Author: Lambertz N
Year: 2015
Journal: BMC Cancer
Title: Downregulation of programmed cell death 10 is associated with tumor cell proliferation, hyperangiogenesis and peritumoral edema in human glioblastoma.
Volume: 15
Pages: 759
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Publication
37688912 | J:341236
First Author: Wang Z
Year: 2023
Journal: Int Immunopharmacol
Title: Tuberous sclerosis complex 1 targeted depletion in macrophages promotes osteogenesis by modulating secretion of Oncostatin M in the inflammatory stage of bone healing.
Volume: 124
Issue: Pt A
Pages: 110895
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Publication
26311783 | J:226167
First Author: Guo S
Year: 2015
Journal: J Neurosci
Title: Oncostatin M Confers Neuroprotection against Ischemic Stroke.
Volume: 35
Issue: 34
Pages: 12047-62
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Publication
22774981 | J:188290
First Author: Upadhyay A
Year: 2012
Journal: Clin Exp Immunol
Title: K/B×N serum transfer arthritis is delayed and less severe in leukaemia inhibitory factor (LIF)-deficient mice.
Volume: 169
Issue: 2
Pages: 71-8
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Publication
31680865 | J:332408
 
First Author: Sims SG
Year: 2019
Journal: Front Cell Neurosci
Title: Janus Kinase 1 Is Required for Transcriptional Reprograming of Murine Astrocytes in Response to Endoplasmic Reticulum Stress.
Volume: 13
Pages: 446
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Publication
30582455 | J:290188
First Author: Ikeda S
Year: 2019
Journal: Circ Res
Title: Hippo Deficiency Leads to Cardiac Dysfunction Accompanied by Cardiomyocyte Dedifferentiation During Pressure Overload.
Volume: 124
Issue: 2
Pages: 292-305
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Publication
15848385 | J:98062
First Author: Fouladi-Nashta AA
Year: 2005
Journal: Dev Biol
Title: Characterization of the uterine phenotype during the peri-implantation period for LIF-null, MF1 strain mice.
Volume: 281
Issue: 1
Pages: 1-21
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Publication
30273401 | J:266636
First Author: van Keulen D
Year: 2018
Journal: PLoS One
Title: Inflammatory cytokine oncostatin M induces endothelial activation in macro- and microvascular endothelial cells and in APOE*3Leiden.CETP mice.
Volume: 13
Issue: 10
Pages: e0204911
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Publication
25432964 | J:227787
First Author: Xiao J
Year: 2015
Journal: Toxicol Sci
Title: Cyclooxygenase-1 serves a vital hepato-protective function in chemically induced acute liver injury.
Volume: 143
Issue: 2
Pages: 430-40
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Publication
17379091 | J:123111
First Author: Broxmeyer HE
Year: 2007
Journal: Exp Hematol
Title: Regulation of myeloid progenitor cell proliferation/survival by IL-31 receptor and IL-31.
Volume: 35
Issue: 4 Suppl 1
Pages: 78-86
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Publication
32019420 | J:314488
First Author: Wang Z
Year: 2021
Journal: Autophagy
Title: Autophagy-based unconventional secretion of HMGB1 by keratinocytes plays a pivotal role in psoriatic skin inflammation.
Volume: 17
Issue: 2
Pages: 529-552
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Protein
O70458
Organism: Mus musculus/domesticus
Length: 971  
Fragment?: false
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Protein
B9EHD2
Organism: Mus musculus/domesticus
Length: 972  
Fragment?: false
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Protein
A0A0R4J268
Organism: Mus musculus/domesticus
Length: 970  
Fragment?: false
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Protein
G3X8V6
Organism: Mus musculus/domesticus
Length: 971  
Fragment?: false
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Protein Coding Gene
MGI:96560 | Il6st
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P42703
Organism: Mus musculus/domesticus
Length: 1092  
Fragment?: false
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Protein
Q3UKU5
Organism: Mus musculus/domesticus
Length: 719  
Fragment?: false
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Protein
Q3U234
Organism: Mus musculus/domesticus
Length: 1092  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom