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Search results 201 to 289 out of 289 for Pabpc1

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Type Details Score
Publication
10534404 | J:58289
First Author: Kleene KC
Year: 1999
Journal: Genomics
Title: The promoter of the Poly(A) binding protein 2 (Pabp2) retroposon is derived from the 5'-untranslated region of the Pabp1 progenitor gene.
Volume: 61
Issue: 2
Pages: 194-200
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Publication
28635594 | J:259256
   
First Author: Zhang X
Year: 2017
Journal: Elife
Title: Translation repression via modulation of the cytoplasmic poly(A)-binding protein in the inflammatory response.
Volume: 6
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Publication
24129315 | J:306378
First Author: Guo A
Year: 2014
Journal: Mol Cell Proteomics
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
Volume: 13
Issue: 1
Pages: 372-87
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Publication
19716330 | J:196089
First Author: Fabian MR
Year: 2009
Journal: Mol Cell
Title: Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.
Volume: 35
Issue: 6
Pages: 868-80
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Publication
28910620 | J:250402
First Author: Hwang HW
Year: 2017
Journal: Neuron
Title: cTag-PAPERCLIP Reveals Alternative Polyadenylation Promotes Cell-Type Specific Protein Diversity and Shifts Araf Isoforms with Microglia Activation.
Volume: 95
Issue: 6
Pages: 1334-1349.e5
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Publication
22621333 | J:187525
First Author: Guzeloglu-Kayisli O
Year: 2012
Journal: Biochem J
Title: Embryonic poly(A)-binding protein (EPAB) is required for oocyte maturation and female fertility in mice.
Volume: 446
Issue: 1
Pages: 47-58
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Publication
23230274 | J:194412
First Author: Takahashi M
Year: 2013
Journal: Mol Cell Biol
Title: Stress granules inhibit apoptosis by reducing reactive oxygen species production.
Volume: 33
Issue: 4
Pages: 815-29
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Publication
28252024 | J:263402
 
First Author: Bayés À
Year: 2017
Journal: Nat Commun
Title: Evolution of complexity in the zebrafish synapse proteome.
Volume: 8
Pages: 14613
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Publication
9883581 | J:51694
First Author: Paynton BV
Year: 1998
Journal: Dev Genet
Title: RNA-binding proteins in mouse oocytes and embryos: expression of genes encoding Y box, DEAD box RNA helicase, and polyA binding proteins.
Volume: 23
Issue: 4
Pages: 285-98
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Publication
1701491 | J:10879
First Author: Rhyner TA
Year: 1990
Journal: J Neurosci Res
Title: Isolation of cDNAs from a mouse astroglial cell line by a subtracted cDNA library.
Volume: 27
Issue: 2
Pages: 144-52
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Publication
17927953 | J:128466
First Author: Nakanishi T
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Disruption of mouse poly(A) polymerase mGLD-2 does not alter polyadenylation status in oocytes and somatic cells.
Volume: 364
Issue: 1
Pages: 14-9
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Publication
26492470 | J:232866
First Author: Yang CR
Year: 2016
Journal: Endocrinology
Title: Embryonic Poly(A)-Binding Protein (EPAB) Is Required for Granulosa Cell EGF Signaling and Cumulus Expansion in Female Mice.
Volume: 157
Issue: 1
Pages: 405-16
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Publication
11322760 | J:71014
First Author: Verlaet M
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Genetic imbalances in preleukemic thymuses.
Volume: 283
Issue: 1
Pages: 12-8
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Publication
21984414 | J:197742
First Author: Pedrotti S
Year: 2012
Journal: Nucleic Acids Res
Title: The RNA recognition motif protein RBM11 is a novel tissue-specific splicing regulator.
Volume: 40
Issue: 3
Pages: 1021-32
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Publication
18625844 | J:139263
First Author: Zheng D
Year: 2008
Journal: J Cell Biol
Title: Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells.
Volume: 182
Issue: 1
Pages: 89-101
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Publication
21262862 | J:170759
First Author: Brouns MR
Year: 2011
Journal: Hum Mol Genet
Title: Over-expression of Grhl2 causes spina bifida in the Axial defects mutant mouse.
Volume: 20
Issue: 8
Pages: 1536-46
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Publication
34784943 | J:317365
First Author: Kurosaki T
Year: 2021
Journal: Genome Biol
Title: NMD abnormalities during brain development in the Fmr1-knockout mouse model of fragile X syndrome.
Volume: 22
Issue: 1
Pages: 317
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Publication
28203794 | J:243134
First Author: Lowther KM
Year: 2017
Journal: Biol Reprod
Title: Embryonic poly(A)-binding protein is required at the preantral stage of mouse folliculogenesis for oocyte-somatic communication.
Volume: 96
Issue: 2
Pages: 341-351
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Publication
36001654 | J:335610
First Author: Qian B
Year: 2022
Journal: Sci Adv
Title: RNA binding protein RBM46 regulates mitotic-to-meiotic transition in spermatogenesis.
Volume: 8
Issue: 34
Pages: eabq2945
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Publication
22863532 | J:361167
First Author: Kawabe Y
Year: 2012
Journal: Cell Stem Cell
Title: Carm1 regulates Pax7 transcriptional activity through MLL1/2 recruitment during asymmetric satellite stem cell divisions.
Volume: 11
Issue: 3
Pages: 333-45
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Publication
37704377 | J:344838
First Author: Sharma S
Year: 2023
Journal: Genes Dev
Title: Uncovering a mammalian neural-specific poly(A) binding protein with unique properties.
Volume: 37
Issue: 15-16
Pages: 760-777
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Publication
11389549 | J:69146
First Author: Hwang SY
Year: 2001
Journal: Mol Reprod Dev
Title: Expression of genes involved in mammalian meiosis during the transition from egg to embryo.
Volume: 59
Issue: 2
Pages: 144-58
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Publication
25157170 | J:216392
First Author: Kraushar ML
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R.
Volume: 111
Issue: 36
Pages: E3815-24
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Publication
16452087 | J:263376
First Author: Trinidad JC
Year: 2006
Journal: Mol Cell Proteomics
Title: Comprehensive identification of phosphorylation sites in postsynaptic density preparations.
Volume: 5
Issue: 5
Pages: 914-22
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Publication
16107646 | J:100324
First Author: Bulfone A
Year: 2005
Journal: J Neurosci
Title: Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.
Volume: 25
Issue: 33
Pages: 7586-600
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Publication
18973680 | J:141291
 
First Author: Tamplin OJ
Year: 2008
Journal: BMC Genomics
Title: Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.
Volume: 9
Pages: 511
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Publication
16033648 | J:103446
 
First Author: McKee AE
Year: 2005
Journal: BMC Dev Biol
Title: A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.
Volume: 5
Pages: 14
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
34143182 | J:309040
 
First Author: Li K
Year: 2021
Journal: J Exp Med
Title: E3 ligase MKRN3 is a tumor suppressor regulating PABPC1 ubiquitination in non-small cell lung cancer.
Volume: 218
Issue: 8
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HT Experiment
E-GEOD-39640 | ATXN2-CAG42 sequesters PABPC1 into insolubility and induces FBXW8 in cerebellum of old ataxic knock-in mice
Series Id: GSE39640
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
23340509 | J:245279
First Author: Huang KL
Year: 2013
Journal: RNA
Title: Phosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fate.
Volume: 19
Issue: 3
Pages: 295-305
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Publication
26912148 | -
 
First Author: Stupfler B
Year: 2016
Journal: Nat Commun
Title: BTG2 bridges PABPC1 RNA-binding domains and CAF1 deadenylase to control cell proliferation.
Volume: 7
Pages: 10811
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Publication
19797087 | -
First Author: Zekri L
Year: 2009
Journal: Mol Cell Biol
Title: The silencing domain of GW182 interacts with PABPC1 to promote translational repression and degradation of microRNA targets and is required for target release.
Volume: 29
Issue: 23
Pages: 6220-31
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Ontology Term
- | Decay of host mRNAs by virus
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Ontology Term
- | Inhibition of host poly(A)-binding protein by virus
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Protein Domain
IPR033503 | GW182
Type: Family
Description: Protein Gawky (also known as GW182) plays a role in RNA-mediated gene silencing by micro-RNAs (miRNAs) [, ]. It is a component of cytoplasmic mRNA processing bodies required for early Drosophila development []. GW182 interacts with AGO1, and this interaction is essential for silencing by miRNAs []. It recruits the CCR4-NOT deadenylase complex through the interaction with PABPC1 [].
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Publication
16177138 | -
First Author: Rehwinkel J
Year: 2005
Journal: RNA
Title: A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing.
Volume: 11
Issue: 11
Pages: 1640-7
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Publication
19304924 | -
First Author: Chekulaeva M
Year: 2009
Journal: RNA
Title: Multiple independent domains of dGW182 function in miRNA-mediated repression in Drosophila.
Volume: 15
Issue: 5
Pages: 794-803
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Publication
16880270 | -
First Author: Schneider MD
Year: 2006
Journal: J Cell Biol
Title: Gawky is a component of cytoplasmic mRNA processing bodies required for early Drosophila development.
Volume: 174
Issue: 3
Pages: 349-58
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Publication
18345015 | -
First Author: Eulalio A
Year: 2008
Journal: Nat Struct Mol Biol
Title: GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay.
Volume: 15
Issue: 4
Pages: 346-53
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Protein Domain
IPR041971 | Gawky_UBA
Type: Domain
Description: This entry represents the UBA domain of Gawky.Protein Gawky (also known as GW182) plays a role in RNA-mediated gene silencing by micro-RNAs (miRNAs) [, ]. It is a component of cytoplasmic mRNA processing bodies required for early Drosophila development []. GW182 interacts with AGO1, and this interaction is essential for silencing by miRNAs []. It recruits the CCR4-NOT deadenylase complex through the interaction with PABPC1 [].
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HT Experiment
E-GEOD-55177 | Ataxin-2 adapts ribosomal mRNA levels and S6 phosphorylation to nutrient availability, with effects on protein synthesis and growth
Series Id: GSE55177
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
26971890 | J:319556
First Author: Kashiwabara S
Year: 2016
Journal: J Reprod Dev
Title: Functional compensation for the loss of testis-specific poly(A)-binding protein, PABPC2, during mouse spermatogenesis.
Volume: 62
Issue: 3
Pages: 305-10
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Publication
16418486 | -
First Author: Boiko AD
Year: 2006
Journal: Genes Dev
Title: A systematic search for downstream mediators of tumor suppressor function of p53 reveals a major role of BTG2 in suppression of Ras-induced transformation.
Volume: 20
Issue: 2
Pages: 236-52
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Protein Domain
IPR033328 | BTG2
Type: Family
Description: BTG2 is a member of the BTG/Tob family. It plays an important role in cellular differentiation and cancer. It is a direct transcriptional target of p53 and has been shown to be a major effector of suppression of Ras-induced transformation by p53 []. BTG2 has been shown to function as a transcription cofactor []. BTG2 is also found to interact directly with the first RRM domain of the poly(A)-binding protein PABPC1 and promoted mRNA poly(A) tail shortening []. In mice, its overexpression during neurogenesis led to microcephaly, while its deletion triggered impaired neuronal differentiation [].The BTG/Tob family members contain an conserved N-terminal domain, known as APRO domain (AntiPROliferative) or BTG domain. In mammals, six family members have been identified: BTG1, BTG2/PC3/Tis21, BTG3/ANA, BTG4/PC3B, Tob1/Tob and Tob2. They interact with CAF1, a subunit of the CCR4-NOT complex. They display antiproliferative properties as their ectopic expression in a variety of cell lines reduced cell proliferation [].
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HT Experiment
GSE57998 | Ataxin-2 modulates mRNA levels of proteins in ribosomal large and small subunit and in translation initiation complex
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
19141475 | J:200392
First Author: Yoh SM
Year: 2008
Journal: Genes Dev
Title: The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation.
Volume: 22
Issue: 24
Pages: 3422-34
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Publication
17785442 | J:129072
First Author: Ezzeddine N
Year: 2007
Journal: Mol Cell Biol
Title: Human TOB, an antiproliferative transcription factor, is a poly(A)-binding protein-dependent positive regulator of cytoplasmic mRNA deadenylation.
Volume: 27
Issue: 22
Pages: 7791-801
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Publication
10617598 | -
First Author: Prévôt D
Year: 2000
Journal: J Biol Chem
Title: The leukemia-associated protein Btg1 and the p53-regulated protein Btg2 interact with the homeoprotein Hoxb9 and enhance its transcriptional activation.
Volume: 275
Issue: 1
Pages: 147-53
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Publication
25721894 | J:261271
First Author: Fittschen M
Year: 2015
Journal: Neurogenetics
Title: Genetic ablation of ataxin-2 increases several global translation factors in their transcript abundance but decreases translation rate.
Volume: 16
Issue: 3
Pages: 181-92
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Protein
Q04211
Organism: Mus musculus/domesticus
Length: 158  
Fragment?: false
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Protein
Q8C2A8
Organism: Mus musculus/domesticus
Length: 158  
Fragment?: false
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Protein
Q3TF68
Organism: Mus musculus/domesticus
Length: 158  
Fragment?: false
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Publication
19746446 | -
First Author: Winkler GS
Year: 2010
Journal: J Cell Physiol
Title: The mammalian anti-proliferative BTG/Tob protein family.
Volume: 222
Issue: 1
Pages: 66-72
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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