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Search results 201 to 252 out of 252 for Pak2

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Type Details Score
Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 619
Description: Phosphoserine; by PAK2
Type: modified residue
End: 619
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UniProt Feature
UniProt Feature
Begin: 618
Description: Phosphoserine; by PAK2
Type: modified residue
End: 618
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UniProt Feature
UniProt Feature
Begin: 93
Description: Phosphothreonine; by PAK2
Type: modified residue
End: 93
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UniProt Feature
UniProt Feature
Begin: 289
Description: Phosphothreonine; by PAK2
Type: modified residue
End: 289
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UniProt Feature
UniProt Feature
Begin: 8
Description: Phosphothreonine; by PAK2
Type: modified residue
End: 8
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UniProt Feature
UniProt Feature
Begin: 2
Description: Phosphothreonine; by PAK2
Type: modified residue
End: 2
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UniProt Feature
UniProt Feature
Begin: 89
Description: Phosphothreonine; by PAK2
Type: modified residue
End: 89
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UniProt Feature
UniProt Feature
Begin: 34
Description: Phosphothreonine; by PAK2
Type: modified residue
End: 34
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UniProt Feature
UniProt Feature
Begin: 39
Description: Phosphoserine; by PAK2
Type: modified residue
End: 39
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UniProt Feature
UniProt Feature
Begin: 339
Description: Phosphoserine; by PAK1, PAK2 and PAK3
Type: modified residue
End: 339
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UniProt Feature
UniProt Feature
Begin: 189
Description: Phosphoserine; by PAK1, PAK2 and PAK3
Type: modified residue
End: 189
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UniProt Feature
UniProt Feature
Begin: 186
Description: Phosphoserine; by PAK1, PAK2 and PAK3
Type: modified residue
End: 186
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Allele
Pak2<em1Smoc> | MGI:7291521
Name: p21 (RAC1) activated kinase 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6771027 | C57BL/6JSmoc-Pak2<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
18161990 | -
First Author: Jung JH
Year: 2008
Journal: Biochemistry
Title: Phosphorylation of c-Abl by protein kinase Pak2 regulates differential binding of ABI2 and CRK.
Volume: 47
Issue: 3
Pages: 1094-104
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Protein Domain
IPR035064 | STK_PAK2
Type: Domain
Description: PAK2 plays a role in pro-apoptotic signaling. It is cleaved and activated by caspases leading to morphological changes during apoptosis []. PAK2 is also activated in response to a variety of stresses including DNA damage, hyperosmolarity, serum starvation, and contact inhibition, and may play a role in coordinating the stress response []. PAK2 also contributes to cancer cell invasion through a mechanism distinct fromthat of PAK1 []. PAK2 belongs to the group I PAKs.Group I PAKs contain a PBD (p21-binding domain) overlapping with an AID (autoinhibitory domain), a C-terminal catalytic domain, SH3 binding sites and a non-classical SH3 binding site for PIX (PAK-interacting exchange factor). PAKs are Rho family GTPase-regulated kinases that serve as important mediators in the function of Cdc42 (cell division cycle 42) and Rac [].This entry corresponds to the PAK2 C-terminal catalytic domain.
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Publication
12411320 | J:115524
First Author: Pearce AC
Year: 2002
Journal: Blood
Title: Vav1, but not Vav2, contributes to platelet aggregation by CRP and thrombin, but neither is required for regulation of phospholipase C.
Volume: 100
Issue: 10
Pages: 3561-9
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Publication
26659946 | J:239043
First Author: Dubrac A
Year: 2016
Journal: Circulation
Title: Targeting NCK-Mediated Endothelial Cell Front-Rear Polarity Inhibits Neovascularization.
Volume: 133
Issue: 4
Pages: 409-21
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Publication
30742951 | J:274324
First Author: Ghatak S
Year: 2019
Journal: Biochim Biophys Acta Gen Subj
Title: Periostin/β1integrin interaction regulates p21-activated kinases in valvular interstitial cell survival and in actin cytoskeleton reorganization.
Volume: 1863
Issue: 5
Pages: 813-829
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Publication
25379771 | J:225315
First Author: Elsherif L
Year: 2014
Journal: PLoS One
Title: Potential compensation among group I PAK members in hindlimb ischemia and wound healing.
Volume: 9
Issue: 11
Pages: e112239
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Publication
10644687 | J:60205
First Author: Cau J
Year: 2000
Journal: J Biol Chem
Title: Regulation of Xenopus p21-activated kinase (X-PAK2) by Cdc42 and maturation-promoting factor controls Xenopus oocyte maturation.
Volume: 275
Issue: 4
Pages: 2367-75
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Publication
25560280 | J:220599
First Author: Yun CY
Year: 2015
Journal: J Invest Dermatol
Title: p21-activated kinase 4 critically regulates melanogenesis via activation of the CREB/MITF and β-catenin/MITF pathways.
Volume: 135
Issue: 5
Pages: 1385-1394
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Publication
36594092 | J:340148
First Author: Yang S
Year: 2023
Journal: Int J Biol Sci
Title: Neutrophil Extracellular Traps Delay Diabetic Wound Healing by Inducing Endothelial-to-Mesenchymal Transition via the Hippo pathway.
Volume: 19
Issue: 1
Pages: 347-361
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Publication
33432150 | J:322006
First Author: Dufies O
Year: 2021
Journal: Nat Microbiol
Title: Escherichia coli Rho GTPase-activating toxin CNF1 mediates NLRP3 inflammasome activation via p21-activated kinases-1/2 during bacteraemia in mice.
Volume: 6
Issue: 3
Pages: 401-412
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Publication
32468886 | J:304167
First Author: Alfaidi M
Year: 2020
Journal: J Am Heart Assoc
Title: Nck1, But Not Nck2, Mediates Disturbed Flow-Induced p21-Activated Kinase Activation and Endothelial Permeability.
Volume: 9
Issue: 11
Pages: e016099
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Publication
17314161 | J:121098
First Author: Priceputu E
Year: 2007
Journal: J Virol
Title: Primary human immunodeficiency virus type 1 nef alleles show major differences in pathogenicity in transgenic mice.
Volume: 81
Issue: 9
Pages: 4677-93
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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