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Search results 201 to 257 out of 257 for Pak3

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Type Details Score
Publication
25053427 | J:214095
First Author: Osipovich AB
Year: 2014
Journal: Development
Title: Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3.
Volume: 141
Issue: 15
Pages: 2939-49
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Publication
19386638 | J:173286
 
First Author: Long JE
Year: 2009
Journal: Cereb Cortex
Title: Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways.
Volume: 19 Suppl 1
Pages: i96-106
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Publication
19521500 | J:149737
First Author: Sansom SN
Year: 2009
Journal: PLoS Genet
Title: The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.
Volume: 5
Issue: 6
Pages: e1000511
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Publication
20436479 | J:157819
First Author: Shimogori T
Year: 2010
Journal: Nat Neurosci
Title: A genomic atlas of mouse hypothalamic development.
Volume: 13
Issue: 6
Pages: 767-75
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
15226823 | J:93300
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
24236816 | J:227963
First Author: Dai X
Year: 2014
Journal: Eur J Neurosci
Title: Dlx1 transcription factor regulates dendritic growth and postsynaptic differentiation through inhibition of neuropilin-2 and PAK3 expression.
Volume: 39
Issue: 4
Pages: 531-47
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UniProt Feature
UniProt Feature
Begin: 339
Description: Phosphoserine; by PAK1, PAK2 and PAK3
Type: modified residue
End: 339
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UniProt Feature
UniProt Feature
Begin: 338
Description: Phosphoserine; by PAK1, PAK2, PAK3 and PAK5
Type: modified residue
End: 338
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UniProt Feature
UniProt Feature
Begin: 189
Description: Phosphoserine; by PAK1, PAK2 and PAK3
Type: modified residue
End: 189
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UniProt Feature
UniProt Feature
Begin: 186
Description: Phosphoserine; by PAK1, PAK2 and PAK3
Type: modified residue
End: 186
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Publication
9065412 | J:231211
First Author: Siow YL
Year: 1997
Journal: J Biol Chem
Title: Identification of two essential phosphorylated threonine residues in the catalytic domain of Mekk1. Indirect activation by Pak3 and protein kinase C.
Volume: 272
Issue: 12
Pages: 7586-94
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Publication
18523455 | -
First Author: Rejeb I
Year: 2008
Journal: Eur J Hum Genet
Title: A novel splice mutation in PAK3 gene underlying mental retardation with neuropsychiatric features.
Volume: 16
Issue: 11
Pages: 1358-63
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Allele
Pak3<tm1.1Rpo> | MGI:6466590
Name: p21 (RAC1) activated kinase 3; targeted mutation 1.1, Roseline Poirier
Allele Type: Targeted
Attribute String: Humanized sequence
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Publication
15574732 | -
First Author: Boda B
Year: 2004
Journal: J Neurosci
Title: The mental retardation protein PAK3 contributes to synapse formation and plasticity in hippocampus.
Volume: 24
Issue: 48
Pages: 10816-25
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Publication
17105769 | -
First Author: Nodé-Langlois R
Year: 2006
Journal: J Cell Sci
Title: Sequential implication of the mental retardation proteins ARHGEF6 and PAK3 in spine morphogenesis.
Volume: 119
Issue: Pt 23
Pages: 4986-93
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Publication
20540949 | -
First Author: Ouyang Y
Year: 2010
Journal: J Mol Biol
Title: Structural and kinetic effects of PAK3 phosphorylation mimic of cTnI(S151E) on the cTnC-cTnI interaction in the cardiac thin filament.
Volume: 400
Issue: 5
Pages: 1036-45
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Genotype
Genotype
Symbol: Pak3/?
Background: B6.129S2(Cg)-Pak3
Zygosity: ot
Has Mutant Allele: true
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DO Term
DOID:0112051 | non-syndromic X-linked intellectual disability 30
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Publication
15581714 | -
 
First Author: van Galen EJ
Year: 2005
Journal: Prog Brain Res
Title: Rho proteins, mental retardation and the neurobiological basis of intelligence.
Volume: 147
Pages: 295-317
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Publication
21949127 | -
First Author: Thévenot E
Year: 2011
Journal: J Biol Chem
Title: p21-Activated kinase 3 (PAK3) protein regulates synaptic transmission through its interaction with the Nck2/Grb4 protein adaptor.
Volume: 286
Issue: 46
Pages: 40044-59
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Protein Domain
IPR035063 | STK_PAK3
Type: Domain
Description: This entry represents the catalytic domain of serine/threonine kinase p21-activated kinase (PAK) 3.PAK3 is highly expressed in the brain. It is implicated in neuronal plasticity, synapse formation, dendritic spine morphogenesis, cell cycle progression, neuronal migration, and apoptosis [, ]. Inactivating mutations in the PAK3 gene cause X-linked non-syndromic mental retardation, the severity of which depends on the site of the mutation [, ]. PAK3 belongs to the group I PAKs.Group I PAKs contain a PBD (p21-binding domain) overlapping with an AID (autoinhibitory domain), a C-terminal catalytic domain, SH3 binding sites and a non-classical SH3 binding site for PIX (PAK-interacting exchange factor). PAKs are Rho family GTPase-regulated kinases that serve as important mediators in the function of Cdc42 (cell division cycle 42) and Rac [].
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Publication
29912324 | J:290113
First Author: Shen W
Year: 2019
Journal: Cereb Cortex
Title: Foxg1 Regulates the Postnatal Development of Cortical Interneurons.
Volume: 29
Issue: 4
Pages: 1547-1560
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Publication
15800193 | J:98630
First Author: Zhang H
Year: 2005
Journal: J Neurosci
Title: A GIT1/PIX/Rac/PAK signaling module regulates spine morphogenesis and synapse formation through MLC.
Volume: 25
Issue: 13
Pages: 3379-88
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Publication
37326884 | J:358596
First Author: Zhang M
Year: 2023
Journal: Neurosci Bull
Title: Neuronal Histone Methyltransferase EZH2 Regulates Neuronal Morphogenesis, Synaptic Plasticity, and Cognitive Behavior in Mice.
Volume: 39
Issue: 10
Pages: 1512-1532
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Publication
28765528 | J:263577
First Author: Zhao M
Year: 2017
Journal: Sci Rep
Title: Pdx1-Cre-driven conditional gene depletion suggests PAK4 as dispensable for mouse pancreas development.
Volume: 7
Issue: 1
Pages: 7031
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Publication
31051214 | J:276346
 
First Author: Wu HY
Year: 2019
Journal: Cancer Lett
Title: p21-Activated kinase 3 promotes cancer stem cell phenotypes through activating the Akt-GSK3β-β-catenin signaling pathway in pancreatic cancer cells.
Volume: 456
Pages: 13-22
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Publication
11950587 | -
First Author: Jaffer ZM
Year: 2002
Journal: Int J Biochem Cell Biol
Title: p21-activated kinases: three more join the Pak.
Volume: 34
Issue: 7
Pages: 713-7
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Protein
Q61036
Organism: Mus musculus/domesticus
Length: 559  
Fragment?: false
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Protein
B1GX80
Organism: Mus musculus/domesticus
Length: 565  
Fragment?: false
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Protein
B1GX81
Organism: Mus musculus/domesticus
Length: 580  
Fragment?: false
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