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Search results 201 to 300 out of 454 for Pbsn

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Hits by Category

Hits by Strain

Type Details Score
Genotype
Genotype
Symbol: Brca2/Brca2 Trp53/Trp53<+> Tg(Pbsn-cre)4Prb/?
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Eif4e/Eif4e Pten/Pten Tg(Pbsn-cre)4Prb/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pten/Pten<+> Tg(Pbsn-cre)4Prb/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pbsn-cre)4Prb/?
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pten/Pten Trp53/Trp53 Tg(Pbsn-cre)4Prb/?
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pten/Pten Smad4/Smad4 Trp53/Trp53 Tg(Pbsn-cre)4Prb/?
Background: involves: 129 * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pten/Pten Tert/Tert Trp53/Trp53 Tg(Pbsn-cre)4Prb/?
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Zfhx3/Zfhx3 Tg(Pbsn-cre)4Prb/?
Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor Pten/Pten Tg(Pbsn-cre)4Prb/?
Background: involves: 129S1/Sv * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Klf5/Klf5 Tg(Pbsn-cre)4Prb/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Klf5/Klf5<+> Tg(Pbsn-cre)4Prb/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Pbsn-FGFR1*K656E)#Wmck/? Tg(Pbsn-FGFR2_iiib*)#Ng/?
Background: involves: FVB
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Apc/Apc Tg(Pbsn-cre)4Prb/?
Background: involves: 129S4/SvJae * C57BL/6 * C57BL/6J * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CAG-cat,-ALOX15)1868Klv/? Tg(Pbsn-cre)4Prb/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CAG-cat,-ALOX15)1868Klv/Tg(CAG-cat,-ALOX15)1868Klv Tg(Pbsn-cre)4Prb/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pbsn-cre)4Prb/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pten/Pten<+> Tg(Pbsn-cre)4Prb/?
Background: involves: 129S1/Sv * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pten/Pten Tg(Pbsn-cre)4Prb/?
Background: involves: 129S1/Sv * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pbsn-cre)4Prb/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Eaf1/Eaf1 Eaf2/Eaf2 Tg(Pbsn-cre)4Prb/?
Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6J * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Eaf1/Eaf1 Tg(Pbsn-cre)4Prb/?
Background: B6(Cg)-Eaf1 Tg(Pbsn-cre)4Prb
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pbsn-cre)4Prb/?
Background: involves: 129 * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor Tg(Pbsn-cre)4Prb/?
Background: involves: 129 * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pten/Pten Rb1/Rb1 Tg(Pbsn-cre)4Prb/?
Background: involves: 129 * 129S1/Sv * 129S6/SvEvTac * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ctnnb1/Ctnnb1 Tg(Pbsn-cre)4Prb/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rb1/Rb1 Trp53/Trp53 Tg(Pbsn-cre)4Prb/?
Background: involves: 129 * 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pten/Pten Tg(Pbsn-cre)4Prb/?
Background: involves: 129S4/SvJae * BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Elac2/Elac2 Tg(Pbsn-cre)4Prb/?
Background: involves: C57BL/6N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Trp53/Trp53 Tg(Pbsn-cre)4Prb/?
Background: involves: 129S4/SvJae * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Publication
18594509 | J:138565
First Author: Jia S
Year: 2008
Journal: Nature
Title: Essential roles of PI(3)K-p110beta in cell growth, metabolism and tumorigenesis.
Volume: 454
Issue: 7205
Pages: 776-9
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Publication
34610416 | J:314038
 
First Author: Kanagasabai T
Year: 2021
Journal: Cancer Lett
Title: MicroRNA-21 deficiency suppresses prostate cancer progression through downregulation of the IRS1-SREBP-1 signaling pathway.
Volume: 525
Pages: 46-54
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Publication
32312982 | J:289154
First Author: Cheng J
Year: 2020
Journal: Nat Commun
Title: TRIM21 and PHLDA3 negatively regulate the crosstalk between the PI3K/AKT pathway and PPP metabolism.
Volume: 11
Issue: 1
Pages: 1880
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Publication
19281769 | J:147066
First Author: Couto SS
Year: 2009
Journal: Differentiation
Title: Simultaneous haploinsufficiency of Pten and Trp53 tumor suppressor genes accelerates tumorigenesis in a mouse model of prostate cancer.
Volume: 77
Issue: 1
Pages: 103-11
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Publication
39609420 | J:359314
First Author: Portale F
Year: 2024
Journal: Nat Commun
Title: C/EBPβ-dependent autophagy inhibition hinders NK cell function in cancer.
Volume: 15
Issue: 1
Pages: 10343
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Publication
22960283 | J:190538
First Author: Simons BW
Year: 2012
Journal: Dev Biol
Title: Wnt signaling though beta-catenin is required for prostate lineage specification.
Volume: 371
Issue: 2
Pages: 246-55
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Publication
38336745 | J:345284
First Author: Kim WK
Year: 2024
Journal: Nat Commun
Title: Androgen deprivation induces double-null prostate cancer via aberrant nuclear export and ribosomal biogenesis through HGF and Wnt activation.
Volume: 15
Issue: 1
Pages: 1231
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Publication
24229711 | J:206734
First Author: Zhao H
Year: 2013
Journal: Cancer Cell
Title: Skp2 deletion unmasks a p27 safeguard that blocks tumorigenesis in the absence of pRb and p53 tumor suppressors.
Volume: 24
Issue: 5
Pages: 645-59
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Publication
35013322 | J:330403
First Author: Qi Z
Year: 2022
Journal: Nat Commun
Title: Overcoming resistance to immune checkpoint therapy in PTEN-null prostate cancer by intermittent anti-PI3Kα/β/δ treatment.
Volume: 13
Issue: 1
Pages: 182
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Publication
26198641 | J:224447
 
First Author: Pencik J
Year: 2015
Journal: Nat Commun
Title: STAT3 regulated ARF expression suppresses prostate cancer metastasis.
Volume: 6
Pages: 7736
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Publication
19117991 | J:143034
First Author: Pearson HB
Year: 2009
Journal: Cancer Res
Title: K-ras and Wnt signaling synergize to accelerate prostate tumorigenesis in the mouse.
Volume: 69
Issue: 1
Pages: 94-101
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Publication
14691534 | J:86212
First Author: Trotman LC
Year: 2003
Journal: PLoS Biol
Title: Pten dose dictates cancer progression in the prostate.
Volume: 1
Issue: 3
Pages: E59
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Publication
29134654 | J:250840
First Author: Jefferies MT
Year: 2017
Journal: J Pathol
Title: PTEN loss and activation of K-RAS and β-catenin cooperate to accelerate prostate tumourigenesis.
Volume: 243
Issue: 4
Pages: 442-456
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Publication
31819003 | J:284956
First Author: Aldahl J
Year: 2020
Journal: J Biol Chem
Title: Aberrant activation of hepatocyte growth factor/MET signaling promotes β-catenin-mediated prostatic tumorigenesis.
Volume: 295
Issue: 2
Pages: 631-644
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Publication
21151173 | J:173730
First Author: Yu X
Year: 2011
Journal: Oncogene
Title: Wnt/β-catenin activation promotes prostate tumor progression in a mouse model.
Volume: 30
Issue: 16
Pages: 1868-79
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Publication
11231059 | J:68167
First Author: Wu X
Year: 2001
Journal: Mech Dev
Title: Generation of a prostate epithelial cell-specific Cre transgenic mouse model for tissue-specific gene ablation.
Volume: 101
Issue: 1-2
Pages: 61-9
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Publication
17553900 | J:122263
First Author: Zhou Z
Year: 2007
Journal: Cancer Res
Title: Prostate cancer associated with p53 and Rb deficiency arises from the stem/progenitor cell-enriched proximal region of prostatic ducts.
Volume: 67
Issue: 12
Pages: 5683-90
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Publication
23630575 | J:200568
First Author: Cheng CY
Year: 2013
Journal: PLoS One
Title: Detection and organ-specific ablation of neuroendocrine cells by synaptophysin locus-based BAC cassette in transgenic mice.
Volume: 8
Issue: 4
Pages: e60905
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Publication
29530483 | J:271107
 
First Author: Lu H
Year: 2018
Journal: Matrix Biol
Title: Exosomal αvβ6 integrin is required for monocyte M2 polarization in prostate cancer.
Volume: 70
Pages: 20-35
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Publication
24910389 | J:316436
First Author: Xie Y
Year: 2014
Journal: Mol Oncol
Title: Slug regulates E-cadherin repression via p19Arf in prostate tumorigenesis.
Volume: 8
Issue: 7
Pages: 1355-64
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Publication
27356744 | J:264783
First Author: Xie Y
Year: 2016
Journal: Oncotarget
Title: MMP7 interacts with ARF in nucleus to potentiate tumor microenvironments for prostate cancer progression in vivo.
Volume: 7
Issue: 30
Pages: 47609-47619
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Publication
29185453 | J:255776
First Author: Xie Y
Year: 2017
Journal: Sci Rep
Title: Dysregulation of YAP by ARF Stimulated with Tea-derived Carbon Nanodots.
Volume: 7
Issue: 1
Pages: 16577
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Publication
20237562 | J:158121
First Author: Lin HK
Year: 2010
Journal: Nature
Title: Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence.
Volume: 464
Issue: 7287
Pages: 374-9
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Publication
20103652 | J:156856
First Author: Thomsen MK
Year: 2010
Journal: Cancer Res
Title: SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formation.
Volume: 70
Issue: 3
Pages: 979-87
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Publication
22341455 | J:186105
First Author: Ding Z
Year: 2012
Journal: Cell
Title: Telomerase reactivation following telomere dysfunction yields murine prostate tumors with bone metastases.
Volume: 148
Issue: 5
Pages: 896-907
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Publication
21703421 | J:173998
First Author: Martin P
Year: 2011
Journal: Am J Pathol
Title: Prostate epithelial Pten/TP53 loss leads to transformation of multipotential progenitors and epithelial to mesenchymal transition.
Volume: 179
Issue: 1
Pages: 422-35
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Publication
35653190 | J:332383
 
First Author: Kumar R
Year: 2022
Journal: J Clin Invest
Title: A mitochondrial unfolded protein response inhibitor suppresses prostate cancer growth in mice via HSP60.
Volume: 132
Issue: 13
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Publication
30467381 | J:349042
First Author: Weng CC
Year: 2019
Journal: Oncogene
Title: Mutant Kras-induced upregulation of CD24 enhances prostate cancer stemness and bone metastasis.
Volume: 38
Issue: 12
Pages: 2005-2019
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Publication
25296641 | J:217182
 
First Author: Chinnam M
Year: 2014
Journal: J Natl Cancer Inst
Title: The Thoc1 ribonucleoprotein and prostate cancer progression.
Volume: 106
Issue: 11
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Publication
29437778 | J:262260
     
First Author: Jurmeister S
Year: 2018
Journal: EMBO Mol Med
Title: Identification of potential therapeutic targets in prostate cancer through a cross-species approach.
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Publication
27669461 | J:239553
First Author: Kim SM
Year: 2016
Journal: J Clin Invest
Title: Targeting cancer metabolism by simultaneously disrupting parallel nutrient access pathways.
Volume: 126
Issue: 11
Pages: 4088-4102
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Publication
38016952 | J:360598
First Author: Ji Y
Year: 2023
Journal: Nat Commun
Title: The ELAVL3/MYCN positive feedback loop provides a therapeutic target for neuroendocrine prostate cancer.
Volume: 14
Issue: 1
Pages: 7794
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Publication
37875657 | J:344826
First Author: Miller KA
Year: 2024
Journal: Oncogene
Title: PTEN-regulated PI3K-p110 and AKT isoform plasticity controls metastatic prostate cancer progression.
Volume: 43
Issue: 1
Pages: 22-34
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Publication
34099734 | J:307910
First Author: Brady NJ
Year: 2021
Journal: Nat Commun
Title: Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer.
Volume: 12
Issue: 1
Pages: 3372
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Publication
25818291 | J:228170
First Author: Mak P
Year: 2015
Journal: Cell Rep
Title: Prostate tumorigenesis induced by PTEN deletion involves estrogen receptor β repression.
Volume: 10
Issue: 12
Pages: 1982-91
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Strain
MGI:5013791 | B6N.CgCop1<tm2.1Vmd> Pten<tm1Hwu> Tg(Pbsn-cre)4Prb
Attribute String: mutant strain, congenic
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Publication
24691769 | J:317509
First Author: Zhang Q
Year: 2014
Journal: Prostate
Title: Interleukin-17 promotes development of castration-resistant prostate cancer potentially through creating an immunotolerant and pro-angiogenic tumor microenvironment.
Volume: 74
Issue: 8
Pages: 869-79
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Publication
25455686 | J:217813
First Author: Burcham GN
Year: 2014
Journal: Am J Pathol
Title: Impact of prostate inflammation on lesion development in the POET3(+)Pten(+/-) mouse model of prostate carcinogenesis.
Volume: 184
Issue: 12
Pages: 3176-91
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Publication
29720449 | J:261540
 
First Author: Nguyen HG
Year: 2018
Journal: Sci Transl Med
Title: Development of a stress response therapy targeting aggressive prostate cancer.
Volume: 10
Issue: 439
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Publication
38781024 | J:351316
 
First Author: Zhang B
Year: 2024
Journal: J Clin Invest
Title: Interruption of KLF5 acetylation promotes PTEN-deficient prostate cancer progression by reprogramming cancer-associated fibroblasts.
Volume: 134
Issue: 14
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Publication
35675421 | J:326992
First Author: Patel R
Year: 2022
Journal: Cancer Res
Title: Cyclocreatine Suppresses Creatine Metabolism and Impairs Prostate Cancer Progression.
Volume: 82
Issue: 14
Pages: 2565-2575
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Publication
39560993 | J:360985
 
First Author: Morel KL
Year: 2024
Journal: J Clin Invest
Title: Low tristetraprolin expression activates phenotypic plasticity and primes transition to lethal prostate cancer in mice.
Volume: 135
Issue: 2
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Publication
23308230 | J:195810
First Author: Kwak MK
Year: 2013
Journal: PLoS One
Title: Conditional deletion of the Pten gene in the mouse prostate induces prostatic intraepithelial neoplasms at early ages but a slow progression to prostate tumors.
Volume: 8
Issue: 1
Pages: e53476
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Publication
28323888 | J:247150
First Author: Yu EJ
Year: 2017
Journal: PLoS One
Title: LZTS2 and PTEN collaboratively regulate ß-catenin in prostatic tumorigenesis.
Volume: 12
Issue: 3
Pages: e0174357
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Publication
28515147 | J:242569
First Author: Loveridge CJ
Year: 2017
Journal: Cancer Res
Title: Increased T-cell Infiltration Elicited by Erk5 Deletion in a Pten-Deficient Mouse Model of Prostate Carcinogenesis.
Volume: 77
Issue: 12
Pages: 3158-3168
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Publication
25425963 | J:243532
First Author: Xing C
Year: 2014
Journal: Neoplasia
Title: Klf5 deletion promotes Pten deletion-initiated luminal-type mouse prostate tumors through multiple oncogenic signaling pathways.
Volume: 16
Issue: 11
Pages: 883-99
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Publication
23201680 | J:194187
First Author: Qin J
Year: 2013
Journal: Nature
Title: COUP-TFII inhibits TGF-β-induced growth barrier to promote prostate tumorigenesis.
Volume: 493
Issue: 7431
Pages: 236-40
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Publication
29844571 | J:277573
First Author: Liao CP
Year: 2018
Journal: Oncogene
Title: Loss of MAOA in epithelia inhibits adenocarcinoma development, cell proliferation and cancer stem cells in prostate.
Volume: 37
Issue: 38
Pages: 5175-5190
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Publication
24480624 | J:208327
First Author: Zhong J
Year: 2014
Journal: Cancer Res
Title: p300 acetyltransferase regulates androgen receptor degradation and PTEN-deficient prostate tumorigenesis.
Volume: 74
Issue: 6
Pages: 1870-1880
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Publication
31366581 | J:279767
 
First Author: Liu Y
Year: 2019
Journal: Sci Transl Med
Title: The androgen receptor regulates a druggable translational regulon in advanced prostate cancer.
Volume: 11
Issue: 503
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Publication
24464914 | J:208332
First Author: Geary LA
Year: 2014
Journal: Mol Cancer Res
Title: CAF-secreted annexin A1 induces prostate cancer cells to gain stem cell-like features.
Volume: 12
Issue: 4
Pages: 607-21
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Publication
28319045 | J:243606
First Author: Li N
Year: 2017
Journal: J Clin Invest
Title: AKT-mediated stabilization of histone methyltransferase WHSC1 promotes prostate cancer metastasis.
Volume: 127
Issue: 4
Pages: 1284-1302
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Publication
23258246 | J:194362
First Author: Jia S
Year: 2013
Journal: Cancer Discov
Title: Opposing effects of androgen deprivation and targeted therapy on prostate cancer prevention.
Volume: 3
Issue: 1
Pages: 44-51
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Publication
23434594 | J:196384
First Author: Patel R
Year: 2013
Journal: J Clin Invest
Title: Sprouty2, PTEN, and PP2A interact to regulate prostate cancer progression.
Volume: 123
Issue: 3
Pages: 1157-75
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Publication
26577921 | J:301636
First Author: Hsieh AC
Year: 2015
Journal: Sci Signal
Title: Cell type-specific abundance of 4EBP1 primes prostate cancer sensitivity or resistance to PI3K pathway inhibitors.
Volume: 8
Issue: 403
Pages: ra116
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Publication
16489020 | J:106650
First Author: Zhong C
Year: 2006
Journal: Cancer Res
Title: Cooperation between FGF8b overexpression and PTEN deficiency in prostate tumorigenesis.
Volume: 66
Issue: 4
Pages: 2188-94
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Publication
16424021 | J:106566
First Author: Khodavirdi AC
Year: 2006
Journal: Cancer Res
Title: Increased expression of osteopontin contributes to the progression of prostate cancer.
Volume: 66
Issue: 2
Pages: 883-8
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Publication
25948589 | J:222960
First Author: Ruscetti M
Year: 2015
Journal: Cancer Res
Title: Tracking and Functional Characterization of Epithelial-Mesenchymal Transition and Mesenchymal Tumor Cells during Prostate Cancer Metastasis.
Volume: 75
Issue: 13
Pages: 2749-59
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Publication
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