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Search results 201 to 300 out of 408 for Pcp2

0.028s
Type Details Score
Allele
Name: transgene insertion 1, Hirokazu Hirai
Allele Type: Transgenic
Attribute String: Epitope tag, Inserted expressed sequence
Allele
Name: transgene insertion 20, Susan L Ackerman
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Publication
First Author: Fuchs M
Year: 1998
Journal: Mech Dev
Title: Differential expression of MAM-subfamily protein tyrosine phosphatases during mouse development.
Volume: 70
Issue: 1-2
Pages: 91-109
Allele
Name: transgene insertion 2, Harry T Orr
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Strain
Attribute String: transgenic, congenic
Publication
First Author: Kostadinov D
Year: 2019
Journal: Nat Neurosci
Title: Predictive and reactive reward signals conveyed by climbing fiber inputs to cerebellar Purkinje cells.
Volume: 22
Issue: 6
Pages: 950-962
Publication
First Author: Lin TF
Year: 2024
Journal: Nat Commun
Title: Intrinsic and synaptic determinants of receptive field plasticity in Purkinje cells of the mouse cerebellum.
Volume: 15
Issue: 1
Pages: 4645
Publication  
First Author: Li SJ
Year: 2023
Journal: Front Neurosci
Title: Meshed neuronal mitochondrial networks empowered by AI-powered classifiers and immersive VR reconstruction.
Volume: 17
Pages: 1059965
Publication
First Author: Behesti H
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: ASTN2 modulates synaptic strength by trafficking and degradation of surface proteins.
Volume: 115
Issue: 41
Pages: E9717-E9726
Strain
Attribute String: transgenic, mutant stock
Publication
First Author: Huynh DP
Year: 2000
Journal: Nat Genet
Title: Nuclear localization or inclusion body formation of ataxin-2 are not necessary for SCA2 pathogenesis in mouse or human.
Volume: 26
Issue: 1
Pages: 44-50
Publication
First Author: Kasumu AW
Year: 2012
Journal: J Neurosci
Title: Chronic suppression of inositol 1,4,5-triphosphate receptor-mediated calcium signaling in cerebellar purkinje cells alleviates pathological phenotype in spinocerebellar ataxia 2 mice.
Volume: 32
Issue: 37
Pages: 12786-96
Publication
First Author: Liu J
Year: 2009
Journal: J Neurosci
Title: Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 2.
Volume: 29
Issue: 29
Pages: 9148-62
Allele
Name: transgene insertion 18, Daniella Carulli
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 50, Stephan L Baader
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion 69, Hsiu M Hsieh-Li
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Publication
First Author: Chang YC
Year: 2011
Journal: J Neurochem
Title: Neuroprotective effects of granulocyte-colony stimulating factor in a novel transgenic mouse model of SCA17.
Volume: 118
Issue: 2
Pages: 288-303
Publication  
First Author: Lin CW
Year: 2020
Journal: Neurosci Lett
Title: ERK activation precedes Purkinje cell loss in mice with Spinocerebellar ataxia type 17.
Volume: 738
Pages: 135337
Strain
Attribute String: transgenic, mutant stock
Allele
Name: transgene insertion 5, Harry T Orr
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion b, Hirokazu Hirai
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Publication
First Author: Marcelo A
Year: 2019
Journal: Hum Mol Genet
Title: Cordycepin activates autophagy through AMPK phosphorylation to reduce abnormalities in Machado-Joseph disease models.
Volume: 28
Issue: 1
Pages: 51-63
Publication  
First Author: Cunha-Santos J
Year: 2016
Journal: Nat Commun
Title: Caloric restriction blocks neuropathology and motor deficits in Machado-Joseph disease mouse models through SIRT1 pathway.
Volume: 7
Pages: 11445
Publication
First Author: Duarte-Neves J
Year: 2015
Journal: Hum Mol Genet
Title: Neuropeptide Y mitigates neuropathology and motor deficits in mouse models of Machado-Joseph disease.
Volume: 24
Issue: 19
Pages: 5451-63
Publication
First Author: Duarte-Neves J
Year: 2021
Journal: Sci Rep
Title: Neuropeptide Y (NPY) intranasal delivery alleviates Machado-Joseph disease.
Volume: 11
Issue: 1
Pages: 3345
Publication
First Author: Simões AT
Year: 2012
Journal: Brain
Title: Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado-Joseph disease.
Volume: 135
Issue: Pt 8
Pages: 2428-39
Publication  
First Author: Oue M
Year: 2009
Journal: Brain Res
Title: Characterization of mutant mice that express polyglutamine in cerebellar Purkinje cells.
Volume: 1255
Pages: 9-17
Publication
First Author: Nóbrega C
Year: 2013
Journal: PLoS One
Title: Silencing mutant ataxin-3 rescues motor deficits and neuropathology in Machado-Joseph disease transgenic mice.
Volume: 8
Issue: 1
Pages: e52396
Publication  
First Author: Yamaura H
Year: 2013
Journal: Neuroscience
Title: Postural dysfunction in a transgenic mouse model of spinocerebellar ataxia type 3.
Volume: 243
Pages: 126-35
Strain
Attribute String: mutant stock, transgenic
Publication
First Author: Chaumont J
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Clusters of cerebellar Purkinje cells control their afferent climbing fiber discharge.
Volume: 110
Issue: 40
Pages: 16223-8
Strain
Attribute String: mutant strain, coisogenic, transgenic
Genotype
Symbol: Rb1/Rb1 Tg(Pcp2-cre)756Mro/?
Background: involves: 129P2/OlaHsd * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Pcp2-SCA2)11Plt/?
Background: involves: C57BL/6J * DBA/2J
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Pcp2-SCA2)11Plt/Tg(Pcp2-SCA2)11Plt
Background: involves: C57BL/6J * DBA/2J
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(Pcp2-SCA7)P7EJman/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Pcp2-TBP*)69Hmhl/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Pcp2-ATXN1*30Q)2Horr/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Pcp2-ATXN1*30Q*S776D)2Horr/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Pcp2-ATXN1*82Q*S776D)5Horr/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Pcp2-ATXN1*30Q)2Horr/Tg(Pcp2-ATXN1*30Q)2Horr
Background: involves: FVB/N
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(Pcp2-ATXN3*69Q)bHirai/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Cacna1a/Cacna1a Tg(Pcp2-TAg)4Horr/?
Background: B6J.Cg-Cacna1a Tg(Pcp2-TAg)4Horr
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Paul S
Year: 2018
Journal: Nat Commun
Title: Staufen1 links RNA stress granules and autophagy in a model of neurodegeneration.
Volume: 9
Issue: 1
Pages: 3648
Publication  
First Author: Wu X
Year: 2023
Journal: Cells
Title: Generation of Conditional Knockout Alleles for PRUNE-1.
Volume: 12
Issue: 4
Allele
Name: transgene insertion 5, Harry T Orr
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Publication  
First Author: Purkartova Z
Year: 2014
Journal: Neurosci Lett
Title: Morphological analysis of embryonic cerebellar grafts in SCA2 mice.
Volume: 558
Pages: 154-8
Publication
First Author: Zhang X
Year: 2001
Journal: Histochem Cell Biol
Title: High level Purkinje cell specific expression of green fluorescent protein in transgenic mice.
Volume: 115
Issue: 6
Pages: 455-64
Allele  
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 71, Elizabeth M Simpson
Allele Type: Targeted
Allele
Name: transgene insertion E330, Zurich
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Genotype
Symbol: Rb1/Rb1 Rbl1/Rbl1 Tg(Pcp2-cre)756Mro/?
Background: involves: 129P2/OlaHsd * FVB
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Todorov B
Year: 2012
Journal: Cerebellum
Title: Purkinje cell-specific ablation of Cav2.1 channels is sufficient to cause cerebellar ataxia in mice.
Volume: 11
Issue: 1
Pages: 246-58
Publication  
First Author: Ju X
Year: 2013
Journal: Neurosci Lett
Title: The role of p38 in mitochondrial respiration in male and female mice.
Volume: 544
Pages: 152-6
Publication
First Author: Hansen ST
Year: 2013
Journal: Hum Mol Genet
Title: Changes in Purkinje cell firing and gene expression precede behavioral pathology in a mouse model of SCA2.
Volume: 22
Issue: 2
Pages: 271-83
Publication
First Author: Woods SM
Year: 2018
Journal: Sci Rep
Title: A comparative analysis of rod bipolar cell transcriptomes identifies novel genes implicated in night vision.
Volume: 8
Issue: 1
Pages: 5506
Publication
First Author: Goswami J
Year: 2005
Journal: Mol Cell Neurosci
Title: Enhanced Purkinje cell survival but compromised cerebellar function in targeted anti-apoptotic protein transgenic mice.
Volume: 29
Issue: 2
Pages: 202-21
Publication  
First Author: Lui NC
Year: 2017
Journal: Nat Commun
Title: Lhx1/5 control dendritogenesis and spine morphogenesis of Purkinje cells via regulation of Espin.
Volume: 8
Pages: 15079
Publication
First Author: Huda F
Year: 2016
Journal: PLoS One
Title: Fusion of Human Fetal Mesenchymal Stem Cells with "Degenerating" Cerebellar Neurons in Spinocerebellar Ataxia Type 1 Model Mice.
Volume: 11
Issue: 11
Pages: e0164202
Publication
First Author: Skinner PJ
Year: 2001
Journal: Am J Pathol
Title: Altered trafficking of membrane proteins in purkinje cells of SCA1 transgenic mice.
Volume: 159
Issue: 3
Pages: 905-13
Publication
First Author: Hearst SM
Year: 2010
Journal: J Neurochem
Title: Dopamine D2 receptor signaling modulates mutant ataxin-1 S776 phosphorylation and aggregation.
Volume: 114
Issue: 3
Pages: 706-16
Publication
First Author: Ripolone M
Year: 2018
Journal: J Neurosci Res
Title: Purkinje cell COX deficiency and mtDNA depletion in an animal model of spinocerebellar ataxia type 1.
Volume: 96
Issue: 9
Pages: 1576-1585
Publication  
First Author: Borgenheimer E
Year: 2022
Journal: Front Cell Neurosci
Title: Single nuclei RNA sequencing investigation of the Purkinje cell and glial changes in the cerebellum of transgenic Spinocerebellar ataxia type 1 mice.
Volume: 16
Pages: 998408
Publication  
First Author: Mellesmoen A
Year: 2018
Journal: Front Cell Neurosci
Title: Brain Derived Neurotrophic Factor (BDNF) Delays Onset of Pathogenesis in Transgenic Mouse Model of Spinocerebellar Ataxia Type 1 (SCA1).
Volume: 12
Pages: 509
Publication
First Author: Kaemmerer WF
Year: 2001
Journal: Neuroscience
Title: Creatine-supplemented diet extends Purkinje cell survival in spinocerebellar ataxia type 1 transgenic mice but does not prevent the ataxic phenotype.
Volume: 103
Issue: 3
Pages: 713-24
Publication
First Author: Inoue T
Year: 2001
Journal: J Neurophysiol
Title: Calcium dynamics and electrophysiological properties of cerebellar Purkinje cells in SCA1 transgenic mice.
Volume: 85
Issue: 4
Pages: 1750-60
Publication  
First Author: Rodriguez-Lebron E
Year: 2013
Journal: Neurobiol Dis
Title: Altered Purkinje cell miRNA expression and SCA1 pathogenesis.
Volume: 54
Pages: 456-63
Publication
First Author: Chopra R
Year: 2018
Journal: PLoS One
Title: Dendritic potassium channel dysfunction may contribute to dendrite degeneration in spinocerebellar ataxia type 1.
Volume: 13
Issue: 5
Pages: e0198040
Strain
Attribute String: coisogenic, mutant strain, transgenic
Publication
First Author: Carulli D
Year: 2002
Journal: Eur J Neurosci
Title: Regenerative and survival capabilities of Purkinje cells overexpressing c-Jun.
Volume: 16
Issue: 1
Pages: 105-18
Publication
First Author: Sillitoe RV
Year: 2009
Journal: Neuroscience
Title: Embryonic origins of ZebrinII parasagittal stripes and establishment of topographic Purkinje cell projections.
Volume: 162
Issue: 3
Pages: 574-88
Strain
Attribute String: congenic, mutant strain, targeted mutation
Publication      
First Author: Pavlovic G
Year: 2013
Journal: MGI Direct Data Submission
Title: Data submissions from the Mouse Clinical Institute (ICS)
Allele
Name: transgene insertion F13, Zurich
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion F332, Zurich
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Publication
First Author: Torashima T
Year: 2008
Journal: EMBO Rep
Title: Lentivector-mediated rescue from cerebellar ataxia in a mouse model of spinocerebellar ataxia.
Volume: 9
Issue: 4
Pages: 393-9
Genotype
Symbol: Pten/Pten Tg(Pcp2-cre)756Mro/?
Background: involves: FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ndufs4/Ndufs4 Tg(Pcp2-cre)3555Jdhu/?
Background: involves: 129S4/SvJaeSor * C3H/HeNCrMtv<-> * C57BL/6NCr
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Hprt1/?
Background: B6.129P2(Cg)-Hprt1/Mmjax
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Pcp2-ATXN1*82Q)5Horr/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Pcp2-ATXN1*82Q)5Horr/Tg(Pcp2-ATXN1*82Q)5Horr
Background: involves: FVB/N
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(Pcp2-cre)3555Jdhu/? Tg(Pcp2-EGFP)2Yuza/? Tsc1/Tsc1
Background: involves: C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Cummings CJ
Year: 1999
Journal: Neuron
Title: Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.
Volume: 24
Issue: 4
Pages: 879-92
Publication
First Author: Nair RR
Year: 2018
Journal: J Neurosci
Title: Impaired Mitochondrial Fatty Acid Synthesis Leads to Neurodegeneration in Mice.
Volume: 38
Issue: 45
Pages: 9781-9800
Publication
First Author: Gilbert R
Year: 2003
Journal: Hum Mol Genet
Title: Prolonged dystrophin expression and functional correction of mdx mouse muscle following gene transfer with a helper-dependent (gutted) adenovirus-encoding murine dystrophin.
Volume: 12
Issue: 11
Pages: 1287-99
Publication  
First Author: Gilhooley MJ
Year: 2021
Journal: Exp Eye Res
Title: ON-bipolar cell gene expression during retinal degeneration: Implications for optogenetic visual restoration.
Volume: 207
Pages: 108553
Strain
Attribute String: mutant stock, targeted mutation, transgenic
Publication
First Author: Asher M
Year: 2021
Journal: Sci Rep
Title: Mood alterations in mouse models of Spinocerebellar Ataxia type 1.
Volume: 11
Issue: 1
Pages: 713
Publication
First Author: Sánchez I
Year: 2016
Journal: Hum Mol Genet
Title: Ataxin-1 regulates the cerebellar bioenergetics proteome through the GSK3β-mTOR pathway which is altered in Spinocerebellar ataxia type 1 (SCA1).
Volume: 25
Issue: 18
Pages: 4021-4040
Publication
First Author: Nayeem N
Year: 2007
Journal: Mol Cell Neurosci
Title: Hyperphosphorylation of tau and neurofilaments and activation of CDK5 and ERK1/2 in PTEN-deficient cerebella.
Volume: 34
Issue: 3
Pages: 400-8
Publication
First Author: Cummings CJ
Year: 2001
Journal: Hum Mol Genet
Title: Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice.
Volume: 10
Issue: 14
Pages: 1511-8
Publication
First Author: Guo L
Year: 2014
Journal: Mol Cell
Title: A cellular system that degrades misfolded proteins and protects against neurodegeneration.
Volume: 55
Issue: 1
Pages: 15-30
Publication
First Author: Yvert G
Year: 2000
Journal: Hum Mol Genet
Title: Expanded polyglutamines induce neurodegeneration and trans-neuronal alterations in cerebellum and retina of SCA7 transgenic mice.
Volume: 9
Issue: 17
Pages: 2491-506
Publication  
First Author: Liu CJ
Year: 2018
Journal: Neurobiol Dis
Title: Polarization-sensitive optical coherence tomography reveals gray matter and white matter atrophy in SCA1 mouse models.
Volume: 116
Pages: 69-77
Publication  
First Author: Blot FGC
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Sphingolipid metabolism governs Purkinje cell patterned degeneration in Atxn1[82Q]/+ mice.
Volume: 118
Issue: 36
Publication    
First Author: Dalal JS
Year: 2021
Journal: Elife
Title: Loss of Tsc1 in cerebellar Purkinje cells induces transcriptional and translation changes in FMRP target transcripts.
Volume: 10
Publication
First Author: Zhang L
Year: 2014
Journal: Neuropsychopharmacology
Title: The knockout of secretin in cerebellar Purkinje cells impairs mouse motor coordination and motor learning.
Volume: 39
Issue: 6
Pages: 1460-8
Publication
First Author: Lowden C
Year: 2021
Journal: Cell Rep
Title: Homeostatic control of nuclear-encoded mitochondrial gene expression by the histone variant H2A.Z is essential for neuronal survival.
Volume: 36
Issue: 11
Pages: 109704
Publication  
First Author: Arsović A
Year: 2020
Journal: Int J Mol Sci
Title: Mouse Ataxin-2 Expansion Downregulates CamKII and Other Calcium Signaling Factors, Impairing Granule-Purkinje Neuron Synaptic Strength.
Volume: 21
Issue: 18
Genotype
Symbol: Atxn1/Atxn1 Tg(Pcp2-ATXN1*82Q)5Horr/?
Background: involves: 129S7/SvEvBrd * FVB/N
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pcp2-cre)756Mro/?
Background: involves: 129S4/SvJaeSor * FVB
Zygosity: cn
Has Mutant Allele: true