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Search results 201 to 300 out of 412 for Pdc

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Type Details Score
Publication
35878016 | J:336519
 
First Author: Simoes DCM
Year: 2022
Journal: J Cell Biol
Title: An integrin axis induces IFN-β production in plasmacytoid dendritic cells.
Volume: 221
Issue: 9
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Publication
27332732 | J:259239
First Author: Wu D
Year: 2016
Journal: Immunity
Title: Type 1 Interferons Induce Changes in Core Metabolism that Are Critical for Immune Function.
Volume: 44
Issue: 6
Pages: 1325-36
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Publication
21115688 | J:176867
First Author: Gregorio J
Year: 2010
Journal: J Exp Med
Title: Plasmacytoid dendritic cells sense skin injury and promote wound healing through type I interferons.
Volume: 207
Issue: 13
Pages: 2921-30
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Publication
27637148 | J:240512
First Author: Sichien D
Year: 2016
Journal: Immunity
Title: IRF8 Transcription Factor Controls Survival and Function of Terminally Differentiated Conventional and Plasmacytoid Dendritic Cells, Respectively.
Volume: 45
Issue: 3
Pages: 626-640
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Publication
22936665 | J:192921
First Author: Weigert A
Year: 2012
Journal: Blood
Title: HIF-1α is a negative regulator of plasmacytoid DC development in vitro and in vivo.
Volume: 120
Issue: 15
Pages: 3001-6
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Publication
22422879 | J:184068
First Author: O'Keeffe M
Year: 2012
Journal: J Immunol
Title: Nonplasmacytoid, high IFN-α-producing, bone marrow dendritic cells.
Volume: 188
Issue: 8
Pages: 3774-83
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Publication
38829740 | J:360189
First Author: De Sá Fernandes C
Year: 2024
Journal: Cell Rep
Title: The histone deacetylase HDAC1 controls dendritic cell development and anti-tumor immunity.
Volume: 43
Issue: 6
Pages: 114308
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Publication
34958351 | J:329864
 
First Author: Anderson DA
Year: 2022
Journal: J Exp Med
Title: Transition from cMyc to L-Myc during dendritic cell development coordinated by rising levels of IRF8.
Volume: 219
Issue: 2
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Publication
30936294 | J:274916
First Author: Chu T
Year: 2019
Journal: J Immunol
Title: Cutting Edge: BCAP Promotes Lupus-like Disease and TLR-Mediated Type I IFN Induction in Plasmacytoid Dendritic Cells.
Volume: 202
Issue: 9
Pages: 2529-2534
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Publication
22948046 | J:192914
First Author: Mitsuhashi Y
Year: 2012
Journal: Blood
Title: Regulation of plasmacytoid dendritic cell responses by PIR-B.
Volume: 120
Issue: 16
Pages: 3256-9
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Publication
22453241 | J:210791
First Author: Talukder AH
Year: 2012
Journal: Cell Res
Title: Phospholipid scramblase 1 regulates Toll-like receptor 9-mediated type I interferon production in plasmacytoid dendritic cells.
Volume: 22
Issue: 7
Pages: 1129-39
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Publication
34449874 | J:322120
First Author: Kobayashi S
Year: 2022
Journal: Int J Cancer
Title: Fatty acid-binding protein 5 limits the generation of Foxp3+ regulatory T cells through regulating plasmacytoid dendritic cell function in the tumor microenvironment.
Volume: 150
Issue: 1
Pages: 152-163
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Publication
18379588 | J:155788
First Author: Bono AV
Year: 2008
Journal: Prostate Cancer Prostatic Dis
Title: Effects of castration on the development of prostate adenocarcinoma from its precursor HGPIN and on the occurrence of androgen-independent, poorly differentiated carcinoma in TRAMP mice.
Volume: 11
Issue: 4
Pages: 377-83
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Publication
19299691 | J:147136
First Author: Kumagai Y
Year: 2009
Journal: J Immunol
Title: Cutting Edge: TLR-Dependent viral recognition along with type I IFN positive feedback signaling masks the requirement of viral replication for IFN-{alpha} production in plasmacytoid dendritic cells.
Volume: 182
Issue: 7
Pages: 3960-4
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Publication
29335542 | J:261541
First Author: Chen J
Year: 2018
Journal: Nat Genet
Title: Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer.
Volume: 50
Issue: 2
Pages: 219-228
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Publication
18758466 | J:140990
First Author: Cao W
Year: 2008
Journal: Nat Immunol
Title: Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway.
Volume: 9
Issue: 10
Pages: 1157-64
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Publication
18854153 | J:147515
First Author: Cisse B
Year: 2008
Journal: Cell
Title: Transcription factor E2-2 is an essential and specific regulator of plasmacytoid dendritic cell development.
Volume: 135
Issue: 1
Pages: 37-48
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Publication
21145760 | J:167292
First Author: Ghosh HS
Year: 2010
Journal: Immunity
Title: Continuous expression of the transcription factor e2-2 maintains the cell fate of mature plasmacytoid dendritic cells.
Volume: 33
Issue: 6
Pages: 905-16
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Publication
20933441 | J:165522
First Author: Sathaliyawala T
Year: 2010
Journal: Immunity
Title: Mammalian target of rapamycin controls dendritic cell development downstream of Flt3 ligand signaling.
Volume: 33
Issue: 4
Pages: 597-606
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Publication
31213723 | J:347205
First Author: Dress RJ
Year: 2019
Journal: Nat Immunol
Title: Plasmacytoid dendritic cells develop from Ly6D(+) lymphoid progenitors distinct from the myeloid lineage.
Volume: 20
Issue: 7
Pages: 852-864
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Publication
20483722 | J:161154
First Author: Okuya K
Year: 2010
Journal: J Immunol
Title: Spatiotemporal regulation of heat shock protein 90-chaperoned self-DNA and CpG-oligodeoxynucleotide for type I IFN induction via targeting to static early endosome.
Volume: 184
Issue: 12
Pages: 7092-9
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Publication
29669251 | J:272658
First Author: Macal M
Year: 2018
Journal: Immunity
Title: Self-Renewal and Toll-like Receptor Signaling Sustain Exhausted Plasmacytoid Dendritic Cells during Chronic Viral Infection.
Volume: 48
Issue: 4
Pages: 730-744.e5
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Publication
21130004 | J:166504
First Author: Swiecki M
Year: 2010
Journal: Immunity
Title: Plasmacytoid dendritic cell ablation impacts early interferon responses and antiviral NK and CD8(+) T cell accrual.
Volume: 33
Issue: 6
Pages: 955-66
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Publication
30611612 | J:282541
First Author: Chopin M
Year: 2019
Journal: Immunity
Title: Transcription Factor PU.1 Promotes Conventional Dendritic Cell Identity and Function via Induction of Transcriptional Regulator DC-SCRIPT.
Volume: 50
Issue: 1
Pages: 77-90.e5
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Publication
29914621 | J:264199
   
First Author: Webster B
Year: 2018
Journal: Elife
Title: Plasmacytoid dendritic cells control dengue and Chikungunya virus infections via IRF7-regulated interferon responses.
Volume: 7
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Publication
23246311 | J:192536
First Author: Koblansky AA
Year: 2013
Journal: Immunity
Title: Recognition of profilin by Toll-like receptor 12 is critical for host resistance to Toxoplasma gondii.
Volume: 38
Issue: 1
Pages: 119-30
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Publication
30087163 | J:265923
First Author: Lau CM
Year: 2018
Journal: J Exp Med
Title: Transcription factor Etv6 regulates functional differentiation of cross-presenting classical dendritic cells.
Volume: 215
Issue: 9
Pages: 2265-2278
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Publication
18055870 | J:131318
First Author: Tailor P
Year: 2008
Journal: Blood
Title: The BXH2 mutation in IRF8 differentially impairs dendritic cell subset development in the mouse.
Volume: 111
Issue: 4
Pages: 1942-5
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Publication
31825848 | J:299208
First Author: Leylek R
Year: 2019
Journal: Cell Rep
Title: Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population.
Volume: 29
Issue: 11
Pages: 3736-3750.e8
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Publication
27986456 | J:240634
First Author: Grajkowska LT
Year: 2017
Journal: Immunity
Title: Isoform-Specific Expression and Feedback Regulation of E Protein TCF4 Control Dendritic Cell Lineage Specification.
Volume: 46
Issue: 1
Pages: 65-77
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Publication
35134331 | J:335932
First Author: Stolp B
Year: 2022
Journal: Cell Rep
Title: SARS-CoV-2 variants of concern display enhanced intrinsic pathogenic properties and expanded organ tropism in mouse models.
Volume: 38
Issue: 7
Pages: 110387
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Publication
15723075 | J:97110
First Author: Hornung V
Year: 2005
Journal: Nat Med
Title: Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7.
Volume: 11
Issue: 3
Pages: 263-70
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Publication
22195962 | J:196247
First Author: Hitosugi T
Year: 2011
Journal: Mol Cell
Title: Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism.
Volume: 44
Issue: 6
Pages: 864-77
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Publication
17038535 | J:144459
First Author: Vremec D
Year: 2007
Journal: Blood
Title: Production of interferons by dendritic cells, plasmacytoid cells, natural killer cells, and interferon-producing killer dendritic cells.
Volume: 109
Issue: 3
Pages: 1165-73
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Publication
19350550 | J:148098
First Author: Toma-Hirano M
Year: 2009
Journal: Eur J Immunol
Title: Ly49Q ligand expressed by activated B cells induces plasmacytoid DC maturation.
Volume: 39
Issue: 5
Pages: 1344-52
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Publication
19340933 | J:154146
First Author: Gouix E
Year: 2009
Journal: Mol Cell Neurosci
Title: Reverse glial glutamate uptake triggers neuronal cell death through extrasynaptic NMDA receptor activation.
Volume: 40
Issue: 4
Pages: 463-73
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Publication
21592863 | J:172590
First Author: Li Q
Year: 2011
Journal: Clin Immunol
Title: The role of interferon alpha in initiation of type I diabetes in the NOD mouse.
Volume: 140
Issue: 1
Pages: 3-7
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Publication
25453760 | J:219299
First Author: Bornstein C
Year: 2014
Journal: Mol Cell
Title: A negative feedback loop of transcription factors specifies alternative dendritic cell chromatin States.
Volume: 56
Issue: 6
Pages: 749-62
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Publication
27149837 | J:235475
     
First Author: Chopin M
Year: 2016
Journal: Cell Rep
Title: RUNX2 Mediates Plasmacytoid Dendritic Cell Egress from the Bone Marrow and Controls Viral Immunity.
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Publication
29358703 | J:259274
First Author: Yang Z
Year: 2018
Journal: Nat Cell Biol
Title: RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis.
Volume: 20
Issue: 2
Pages: 186-197
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Publication
33078848 | J:304451
First Author: Pöysti S
Year: 2021
Journal: Eur J Immunol
Title: Plasmacytoid dendritic cells regulate host immune response to Citrobacter rodentium induced colitis in colon-draining lymph nodes.
Volume: 51
Issue: 3
Pages: 620-625
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Publication
35180378 | J:325996
First Author: Feng J
Year: 2022
Journal: Immunity
Title: Clonal lineage tracing reveals shared origin of conventional and plasmacytoid dendritic cells.
Volume: 55
Issue: 3
Pages: 405-422.e11
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Publication
39747033 | J:360776
First Author: Di Michele M
Year: 2025
Journal: Nat Commun
Title: E4F1 coordinates pyruvate metabolism and the activity of the elongator complex to ensure translation fidelity during brain development.
Volume: 16
Issue: 1
Pages: 67
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Publication
39885202 | J:361585
First Author: Jia Y
Year: 2025
Journal: Nat Commun
Title: Mitochondrial KMT9 methylates DLAT to control pyruvate dehydrogenase activity and prostate cancer growth.
Volume: 16
Issue: 1
Pages: 1191
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Publication
2649080 | -
First Author: Yeaman SJ
Year: 1989
Journal: Biochem J
Title: The 2-oxo acid dehydrogenase complexes: recent advances.
Volume: 257
Issue: 3
Pages: 625-32
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Publication
3522581 | -
First Author: Fujiwara K
Year: 1986
Journal: J Biol Chem
Title: Chicken liver H-protein, a component of the glycine cleavage system. Amino acid sequence and identification of the N epsilon-lipoyllysine residue.
Volume: 261
Issue: 19
Pages: 8836-41
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Publication
2682658 | -
First Author: Behal RH
Year: 1989
Journal: Proc Natl Acad Sci U S A
Title: Cloning and nucleotide sequence of the gene for protein X from Saccharomyces cerevisiae.
Volume: 86
Issue: 22
Pages: 8732-6
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Protein Domain
IPR003016 | 2-oxoA_DH_lipoyl-BS
Type: Binding_site
Description: The 2-oxo acid dehydrogenase multienzyme complexes []from bacterial andeukaryotic sources catalyze the oxidative decarboxylation of 2-oxo acids tothe corresponding acyl-CoA. These include: Pyruvate dehydrogenase complex (PDC). 2-oxoglutarate dehydrogenase complex (OGDC). Branched-chain 2-oxo acid dehydrogenase complex (BCOADC). These three complexes share a common architecture: they are composed ofmultiple copies of three component enzymes - E1, E2 and E3. E1 is a thiaminepyrophosphate-dependent 2-oxo acid dehydrogenase, E2 a dihydrolipamideacyltransferase, and E3 an FAD-containing dihydrolipamide dehydrogenase. E2 acyltransferases have an essential cofactor, lipoic acid, which iscovalently bound via a amide linkage to a lysine group. The E2 components ofOGCD and BCOACD bind a single lipoyl group, while those of PDC bind either one(in yeast and in Bacillus), two (in mammals), or three (in Azotobacter and inEscherichia coli) lipoyl groups []. In addition to the E2 components of the three enzymatic complexes describedabove, a lipoic acid cofactor is also found in the following proteins: H-protein of the glycine cleavage system (GCS) []. GCS is a multienzymecomplex of four protein components, which catalyzes the degradation ofglycine. H protein shuttles the methylamine group of glycine from the Pprotein to the T protein. H-protein from either prokaryotes or eukaryotesbinds a single lipoic group. Mammalian and yeast pyruvate dehydrogenase complexes differ from that ofother sources, in that they contain, in small amounts, a protein of unknownfunction - designated protein X or component X. Its sequence is closelyrelated to that of E2 subunits and seems to bind a lipoic group []. Fast migrating protein (FMP) (gene acoC) from Ralstonia eutropha (Alcaligenes eutrophus) [].This protein is most probably a dihydrolipamide acyltransferase involved inacetoin metabolism. This signature contains the lipoyl-binding lysine residue. The domain surronding this site is evolutionary related to that around the biotin-binding lysine residue of biotin requiring enzymes.
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Protein
A2AWH8
Organism: Mus musculus/domesticus
Length: 220  
Fragment?: false
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Protein
A2AWH7
Organism: Mus musculus/domesticus
Length: 218  
Fragment?: true
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Publication
2061286 | -
First Author: Priefert H
Year: 1991
Journal: J Bacteriol
Title: Identification and molecular characterization of the Alcaligenes eutrophus H16 aco operon genes involved in acetoin catabolism.
Volume: 173
Issue: 13
Pages: 4056-71
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Publication
19201841 | J:144806
First Author: Workman CJ
Year: 2009
Journal: J Immunol
Title: LAG-3 regulates plasmacytoid dendritic cell homeostasis.
Volume: 182
Issue: 4
Pages: 1885-91
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Publication
28225814 | J:245172
First Author: Furuta Y
Year: 2017
Journal: PLoS One
Title: E-NPP3 controls plasmacytoid dendritic cell numbers in the small intestine.
Volume: 12
Issue: 2
Pages: e0172509
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Publication
21190881 | J:168464
First Author: Ushikai M
Year: 2011
Journal: Mol Genet Metab
Title: Induction of PDK4 in the heart muscle of JVS mice, an animal model of systemic carnitine deficiency, does not appear to reduce glucose utilization by the heart.
Volume: 102
Issue: 3
Pages: 349-55
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Publication
16606348 | J:115895
First Author: Jeoung NH
Year: 2006
Journal: Biochem J
Title: Role of pyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) in glucose homoeostasis during starvation.
Volume: 397
Issue: 3
Pages: 417-25
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Publication
18430968 | J:137665
First Author: Jeoung NH
Year: 2008
Journal: Am J Physiol Endocrinol Metab
Title: Pyruvate dehydrogenase kinase-4 deficiency lowers blood glucose and improves glucose tolerance in diet-induced obese mice.
Volume: 295
Issue: 1
Pages: E46-54
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Publication
21045126 | J:166600
First Author: Blasius AL
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells.
Volume: 107
Issue: 46
Pages: 19973-8
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Publication
30262916 | J:278269
First Author: Griffith AD
Year: 2018
Journal: Sci Rep
Title: A requirement for slc15a4 in imiquimod-induced systemic inflammation and psoriasiform inflammation in mice.
Volume: 8
Issue: 1
Pages: 14451
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Publication
11708858 | J:74192
First Author: Johnson MT
Year: 2001
Journal: Mol Genet Metab
Title: Inactivation of the murine pyruvate dehydrogenase (Pdha1) gene and its effect on early embryonic development.
Volume: 74
Issue: 3
Pages: 293-302
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Publication
18586888 | J:141289
First Author: Sidhu S
Year: 2008
Journal: Am J Physiol Heart Circ Physiol
Title: Tissue-specific pyruvate dehydrogenase complex deficiency causes cardiac hypertrophy and sudden death of weaned male mice.
Volume: 295
Issue: 3
Pages: H946-H952
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Publication
20841503 | J:170211
First Author: Srinivasan M
Year: 2010
Journal: Am J Physiol Endocrinol Metab
Title: ß-Cell-specific pyruvate dehydrogenase deficiency impairs glucose-stimulated insulin secretion.
Volume: 299
Issue: 6
Pages: E910-7
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Publication
23479228 | J:194900
First Author: Rahim MM
Year: 2013
Journal: J Immunol
Title: Ly49Q positively regulates type I IFN production by plasmacytoid dendritic cells in an immunoreceptor tyrosine-based inhibitory motif-dependent manner.
Volume: 190
Issue: 8
Pages: 3994-4004
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Publication
23018460 | J:190612
First Author: Ito R
Year: 2012
Journal: J Immunol
Title: Efficient xenoengraftment in severe immunodeficient NOD/Shi-scid IL2rγnull mice is attributed to a lack of CD11c+B220+CD122+ cells.
Volume: 189
Issue: 9
Pages: 4313-20
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Publication
22388324 | J:198616
First Author: Döring Y
Year: 2012
Journal: Circulation
Title: Auto-antigenic protein-DNA complexes stimulate plasmacytoid dendritic cells to promote atherosclerosis.
Volume: 125
Issue: 13
Pages: 1673-83
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Publication
30131424 | J:267220
 
First Author: Tomasello E
Year: 2018
Journal: EMBO J
Title: Molecular dissection of plasmacytoid dendritic cell activation in vivo during a viral infection.
Volume: 37
Issue: 19
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Publication
25223984 | J:234151
First Author: Sage AP
Year: 2014
Journal: Circulation
Title: MHC Class II-restricted antigen presentation by plasmacytoid dendritic cells drives proatherogenic T cell immunity.
Volume: 130
Issue: 16
Pages: 1363-73
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Publication
22315415 | J:182008
First Author: Cervantes-Barragan L
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Plasmacytoid dendritic cells control T-cell response to chronic viral infection.
Volume: 109
Issue: 8
Pages: 3012-7
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Publication
16301633 | J:122144
First Author: Yang GX
Year: 2005
Journal: J Immunol
Title: Plasmacytoid dendritic cells of different origins have distinct characteristics and function: studies of lymphoid progenitors versus myeloid progenitors.
Volume: 175
Issue: 11
Pages: 7281-7
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Publication
31264967 | J:282050
First Author: Koda Y
Year: 2019
Journal: J Clin Invest
Title: Plasmacytoid dendritic cells protect against immune-mediated acute liver injury via IL-35.
Volume: 129
Issue: 8
Pages: 3201-3213
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Publication
17407097 | J:123560
First Author: Barr DP
Year: 2007
Journal: Eur J Immunol
Title: A role for plasmacytoid dendritic cells in the rapid IL-18-dependent activation of NK cells following HSV-1 infection.
Volume: 37
Issue: 5
Pages: 1334-42
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Publication
16037393 | J:124073
First Author: O'Keeffe M
Year: 2005
Journal: Blood
Title: Distinct roles for the NF-kappaB1 and c-Rel transcription factors in the differentiation and survival of plasmacytoid and conventional dendritic cells activated by TLR-9 signals.
Volume: 106
Issue: 10
Pages: 3457-64
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Publication
27792766 | J:245864
First Author: Spaulding E
Year: 2016
Journal: PLoS Pathog
Title: STING-Licensed Macrophages Prime Type I IFN Production by Plasmacytoid Dendritic Cells in the Bone Marrow during Severe Plasmodium yoelii Malaria.
Volume: 12
Issue: 10
Pages: e1005975
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Publication
18424703 | J:134320
First Author: Fujiwara D
Year: 2008
Journal: J Immunol
Title: Systemic control of plasmacytoid dendritic cells by CD8+ T cells and commensal microbiota.
Volume: 180
Issue: 9
Pages: 5843-52
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Publication
22547694 | J:186009
First Author: Pelletier AN
Year: 2012
Journal: J Immunol
Title: The size of the plasmacytoid dendritic cell compartment is a multigenic trait dominated by a locus on mouse chromosome 7.
Volume: 188
Issue: 11
Pages: 5561-70
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Publication
11697863 | J:72837
First Author: Sugden MC
Year: 2001
Journal: Arch Biochem Biophys
Title: Role of peroxisome proliferator-activated receptor-alpha in the mechanism underlying changes in renal pyruvate dehydrogenase kinase isoform 4 protein expression in starvation and after refeeding.
Volume: 395
Issue: 2
Pages: 246-52
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Publication
22634622 | J:188949
First Author: Umemoto E
Year: 2012
Journal: J Immunol
Title: Constitutive plasmacytoid dendritic cell migration to the splenic white pulp is cooperatively regulated by CCR7- and CXCR4-mediated signaling.
Volume: 189
Issue: 1
Pages: 191-9
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Publication
31293597 | J:283609
 
First Author: Shimizu K
Year: 2019
Journal: Front Immunol
Title: Granzyme A Stimulates pDCs to Promote Adaptive Immunity via Induction of Type I IFN.
Volume: 10
Pages: 1450
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Publication
25833958 | J:222635
First Author: Biswas M
Year: 2015
Journal: Blood
Title: Synergy between rapamycin and FLT3 ligand enhances plasmacytoid dendritic cell-dependent induction of CD4+CD25+FoxP3+ Treg.
Volume: 125
Issue: 19
Pages: 2937-47
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Publication
31668809 | J:292664
First Author: Kobayashi S
Year: 2020
Journal: Biochem Biophys Res Commun
Title: TRAF5 promotes plasmacytoid dendritic cell development from bone marrow progenitors.
Volume: 521
Issue: 2
Pages: 353-359
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Publication
23337808 | J:196418
First Author: Prete F
Year: 2013
Journal: J Exp Med
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