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Search results 201 to 300 out of 506 for Pick1

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0.027s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Protein
D6RFR7
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: false
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Protein
Q8CA59
Organism: Mus musculus/domesticus
Length: 130  
Fragment?: true
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Protein
A2A5V1
Organism: Mus musculus/domesticus
Length: 55  
Fragment?: true
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Protein
D3Z340
Organism: Mus musculus/domesticus
Length: 209  
Fragment?: true
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Protein
B1AV64
Organism: Mus musculus/domesticus
Length: 129  
Fragment?: true
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Protein
Q8C914
Organism: Mus musculus/domesticus
Length: 97  
Fragment?: true
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Protein
H3BL43
Organism: Mus musculus/domesticus
Length: 95  
Fragment?: true
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Protein
A0A1L1SSL0
Organism: Mus musculus/domesticus
Length: 180  
Fragment?: true
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Protein
Q9D333
Organism: Mus musculus/domesticus
Length: 139  
Fragment?: false
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Publication
17254796 | -
First Author: Laezza F
Year: 2007
Journal: Mol Cell Neurosci
Title: KRIP6: a novel BTB/kelch protein regulating function of kainate receptors.
Volume: 34
Issue: 4
Pages: 539-50
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Publication
16319878 | -
First Author: McMahon HT
Year: 2005
Journal: Nature
Title: Membrane curvature and mechanisms of dynamic cell membrane remodelling.
Volume: 438
Issue: 7068
Pages: 590-6
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Protein Domain
IPR030596 | KLHL24
Type: Family
Description: Kelch-like protein 24 (KLHL24, also known as KRIP6) belongs to the KLHL family []. KRIP6 binds to and regulates the GluR6a kainate receptor []. It also modulates the interaction of PICK1 with GluR6 kainate receptors []. Kainate receptors (KAR) are ionotropic receptors that respond to the neurotransmitter glutamate and have been implicated in epilepsy, stroke, Alzheimer's and neuropathic pain [].The KLHL (Kelch-like) proteins generally have a BTB/POZ domain, a BACK domain, and five to six Kelch motifs. They constitute a subgroup at the intersection between the BTB/POZ domain and Kelch domain superfamilies. The BTB/POZ domain facilitates protein binding [], while the Kelch domain (repeats) form β-propellers. The Kelch superfamily of proteins can be subdivided into five groups: (1) N-propeller, C-dimer proteins, (2) N-propeller proteins, (3) propeller proteins, (4) N-dimer, C-propeller proteins, and (5) C-propeller proteins. KLHL family members belong to the N-dimer, C-propeller subclass of Kelch repeat proteins []. In addition to BTB/POZ and Kelch domains, the KLHL family members contain a BACK domain, first described as a 130-residue region of conservation observed amongst BTB-Kelch proteins []. Many of the Kelch-like proteins have been identified as adaptors for the recruitment of substrates to Cul3-based E3 ubiquitin ligases [, ].
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Protein Domain
IPR027267 | AH/BAR_dom_sf
Type: Homologous_superfamily
Description: This superfamily represents a structural domain which consists of three α-helices, including the arfaptin homology (AH) domain and the BAR (Bin-Amphiphysin-Rvs) domain.The arfaptin homology (AH) domain is a protein domain found in a range of proteins, including arfaptins, protein kinase C-binding protein PICK1 []and mammalian 69kDa islet cell autoantigen (ICA69) []. The AH domain of arfaptin has been shown to dimerise and to bind Arf and Rho family GTPases [, ], including ARF1, a small GTPase involved in vesicle budding at the Golgi complex and immature secretory granules. The AH domain consists of three α-helices arranged as an extended antiparallel α-helical bundle. Two arfaptin AH domains associate to form a highly elongated, crescent-shaped dimer [, ].Members of the Amphiphysin protein family are key regulators in the early steps of endocytosis, involved in the formation of clathrin-coated vesicles by promoting the assembly of a protein complex at the plasma membrane and directly assist in the induction of the high curvature of the membrane at the neck of the vesicle. Amphiphysins contain a characteristic domain, known as the BAR (Bin-Amphiphysin-Rvs) domain, which is required for their in vivofunction and their ability to tubulate membranes []. The crystal structure of these proteins suggest the domain forms a crescent-shaped dimer of a three-helix coiled coil with a characteristic set of conserved hydrophobic, aromatic and hydrophilic amino acids. Proteins containing this domain have been shown to homodimerise, heterodimerise or, in a few cases, interact with small GTPases.
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Protein
P97411
Organism: Mus musculus/domesticus
Length: 478  
Fragment?: false
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Protein
S4R217
Organism: Mus musculus/domesticus
Length: 302  
Fragment?: false
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Protein
A5A8K4
Organism: Mus musculus/domesticus
Length: 478  
Fragment?: false
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Protein
D3Z118
Organism: Mus musculus/domesticus
Length: 465  
Fragment?: false
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Protein
B7ZWE9
Organism: Mus musculus/domesticus
Length: 232  
Fragment?: true
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Protein
Q9D0J3
Organism: Mus musculus/domesticus
Length: 109  
Fragment?: false
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Protein
D3Z1X5
Organism: Mus musculus/domesticus
Length: 170  
Fragment?: true
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Protein
H3BK40
Organism: Mus musculus/domesticus
Length: 211  
Fragment?: true
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Protein
A0A2R8W6H4
Organism: Mus musculus/domesticus
Length: 142  
Fragment?: false
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Protein
S4R1Q1
Organism: Mus musculus/domesticus
Length: 160  
Fragment?: true
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Protein
Q8C9L7
Organism: Mus musculus/domesticus
Length: 138  
Fragment?: true
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Protein
Q9CTN7
Organism: Mus musculus/domesticus
Length: 127  
Fragment?: true
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Protein
A0A0U1RNM6
Organism: Mus musculus/domesticus
Length: 230  
Fragment?: false
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Protein
F6ZL13
Organism: Mus musculus/domesticus
Length: 231  
Fragment?: true
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Protein
S4R2T6
Organism: Mus musculus/domesticus
Length: 209  
Fragment?: false
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Protein
A2ALV1
Organism: Mus musculus/domesticus
Length: 182  
Fragment?: false
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Protein
Q8BXU5
Organism: Mus musculus/domesticus
Length: 245  
Fragment?: false
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Publication
21713671 | -
 
First Author: Marshall J
Year: 2011
Journal: Adv Exp Med Biol
Title: BTB-Kelch proteins and ubiquitination of kainate receptors.
Volume: 717
Pages: 115-25
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Protein
Q3V2J0
Organism: Mus musculus/domesticus
Length: 292  
Fragment?: false
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Protein
Q9JI08
Organism: Mus musculus/domesticus
Length: 253  
Fragment?: false
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Protein
Q8BP22
Organism: Mus musculus/domesticus
Length: 286  
Fragment?: false
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Protein
J3QK75
Organism: Mus musculus/domesticus
Length: 132  
Fragment?: true
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Protein
A0A3B2W4F1
Organism: Mus musculus/domesticus
Length: 160  
Fragment?: true
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Protein
E9QA76
Organism: Mus musculus/domesticus
Length: 57  
Fragment?: false
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Protein
A0A0G2JE45
Organism: Mus musculus/domesticus
Length: 194  
Fragment?: true
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Protein
A0A338P6N7
Organism: Mus musculus/domesticus
Length: 223  
Fragment?: true
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Protein
Z4YJZ2
Organism: Mus musculus/domesticus
Length: 351  
Fragment?: false
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Protein
Q8C684
Organism: Mus musculus/domesticus
Length: 245  
Fragment?: true
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Protein
B1AUY1
Organism: Mus musculus/domesticus
Length: 214  
Fragment?: true
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Protein
A0A3B2W7K0
Organism: Mus musculus/domesticus
Length: 247  
Fragment?: false
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Protein
Q3TC47
Organism: Mus musculus/domesticus
Length: 253  
Fragment?: false
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Protein
Q8R0Z4
Organism: Mus musculus/domesticus
Length: 172  
Fragment?: false
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Protein
A0A0G2JEL5
Organism: Mus musculus/domesticus
Length: 272  
Fragment?: true
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Protein
J3KMP6
Organism: Mus musculus/domesticus
Length: 355  
Fragment?: false
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Protein
A0A3Q4EBR8
Organism: Mus musculus/domesticus
Length: 120  
Fragment?: true
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Protein
F6VZK2
Organism: Mus musculus/domesticus
Length: 216  
Fragment?: true
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Protein
A0A338P6H1
Organism: Mus musculus/domesticus
Length: 136  
Fragment?: true
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Protein
J3QQ08
Organism: Mus musculus/domesticus
Length: 65  
Fragment?: false
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Publication
14993925 | -
First Author: Habermann B
Year: 2004
Journal: EMBO Rep
Title: The BAR-domain family of proteins: a case of bending and binding?
Volume: 5
Issue: 3
Pages: 250-5
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Protein
P55194
Organism: Mus musculus/domesticus
Length: 680  
Fragment?: false
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Protein
Q99J31
Organism: Mus musculus/domesticus
Length: 802  
Fragment?: false
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Protein
Q6PGG2
Organism: Mus musculus/domesticus
Length: 971  
Fragment?: false
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Protein
Q8CGF1
Organism: Mus musculus/domesticus
Length: 1266  
Fragment?: false
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Protein
D3Z6Q9
Organism: Mus musculus/domesticus
Length: 489  
Fragment?: false
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Protein
Q3UQN2
Organism: Mus musculus/domesticus
Length: 809  
Fragment?: false
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Protein
Q8R1S4
Organism: Mus musculus/domesticus
Length: 759  
Fragment?: false
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Protein
Q6P9S0
Organism: Mus musculus/domesticus
Length: 715  
Fragment?: false
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Protein
Q80ZJ7
Organism: Mus musculus/domesticus
Length: 404  
Fragment?: false
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Protein
Q5SSM3
Organism: Mus musculus/domesticus
Length: 814  
Fragment?: false
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Protein
Q3UIA2
Organism: Mus musculus/domesticus
Length: 846  
Fragment?: false
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Protein
Q9CY18
Organism: Mus musculus/domesticus
Length: 387  
Fragment?: false
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Protein
Q8CE50
Organism: Mus musculus/domesticus
Length: 437  
Fragment?: false
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Protein
A0A0U1RPB9
Organism: Mus musculus/domesticus
Length: 173  
Fragment?: false
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Protein
F7D3B8
Organism: Mus musculus/domesticus
Length: 362  
Fragment?: true
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Protein
Q8CGG9
Organism: Mus musculus/domesticus
Length: 213  
Fragment?: true
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Protein
Q32MS3
Organism: Mus musculus/domesticus
Length: 450  
Fragment?: false
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Protein
Q8BXH2
Organism: Mus musculus/domesticus
Length: 250  
Fragment?: false
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Protein
Q3U3Y3
Organism: Mus musculus/domesticus
Length: 405  
Fragment?: true
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Protein
A2A5V3
Organism: Mus musculus/domesticus
Length: 582  
Fragment?: false
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Protein
Q3TXT4
Organism: Mus musculus/domesticus
Length: 299  
Fragment?: false
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Protein
Q6A091
Organism: Mus musculus/domesticus
Length: 512  
Fragment?: true
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Protein
Q3TC10
Organism: Mus musculus/domesticus
Length: 336  
Fragment?: false
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Protein
G3X9H7
Organism: Mus musculus/domesticus
Length: 759  
Fragment?: false
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Protein
A0A494B972
Organism: Mus musculus/domesticus
Length: 451  
Fragment?: false
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Protein
S4R171
Organism: Mus musculus/domesticus
Length: 210  
Fragment?: true
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Protein
F6RSR4
Organism: Mus musculus/domesticus
Length: 386  
Fragment?: true
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Protein
Q9CRE2
Organism: Mus musculus/domesticus
Length: 150  
Fragment?: true
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Protein
Q3TV50
Organism: Mus musculus/domesticus
Length: 282  
Fragment?: false
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Protein
B1AW94
Organism: Mus musculus/domesticus
Length: 114  
Fragment?: true
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Protein
S4R1B8
Organism: Mus musculus/domesticus
Length: 478  
Fragment?: false
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Protein
A2AQ47
Organism: Mus musculus/domesticus
Length: 160  
Fragment?: true
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Protein
F6S054
Organism: Mus musculus/domesticus
Length: 289  
Fragment?: true
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Protein
Q6ZQB7
Organism: Mus musculus/domesticus
Length: 773  
Fragment?: true
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Protein
Q6A075
Organism: Mus musculus/domesticus
Length: 351  
Fragment?: true
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Protein
D6RCG0
Organism: Mus musculus/domesticus
Length: 304  
Fragment?: false
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Protein
A0A0U1RQ80
Organism: Mus musculus/domesticus
Length: 177  
Fragment?: false
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Protein
Q3UPB8
Organism: Mus musculus/domesticus
Length: 173  
Fragment?: false
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Protein
F6T1Y2
Organism: Mus musculus/domesticus
Length: 645  
Fragment?: true
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Protein
Q05CX7
Organism: Mus musculus/domesticus
Length: 288  
Fragment?: true
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Protein
F8WI30
Organism: Mus musculus/domesticus
Length: 445  
Fragment?: false
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Protein
F7D291
Organism: Mus musculus/domesticus
Length: 364  
Fragment?: true
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Protein
B1AW92
Organism: Mus musculus/domesticus
Length: 95  
Fragment?: true
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Protein
E9PVQ1
Organism: Mus musculus/domesticus
Length: 137  
Fragment?: true
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Protein
B1AW93
Organism: Mus musculus/domesticus
Length: 125  
Fragment?: true
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Protein
A0A2R8W6I7
Organism: Mus musculus/domesticus
Length: 596  
Fragment?: false
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Protein
Q8BYX6
Organism: Mus musculus/domesticus
Length: 159  
Fragment?: true
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Protein
A0A2X0SSN2
Organism: Mus musculus/domesticus
Length: 804  
Fragment?: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom