Type |
Details |
Score |
Publication |
First Author: |
Park JM |
Year: |
2013 |
Journal: |
Cell |
Title: |
A prolyl-isomerase mediates dopamine-dependent plasticity and cocaine motor sensitization. |
Volume: |
154 |
Issue: |
3 |
Pages: |
637-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory DNA Panel Mapping Resource |
Year: |
1999 |
Journal: |
Database Release |
Title: |
JAX Interspecific Backcross BSS and BSB Public Mapping Data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Brady KP |
Year: |
1997 |
Journal: |
Genome Res |
Title: |
Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis. |
Volume: |
7 |
Issue: |
11 |
Pages: |
1085-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tang F |
Year: |
2011 |
Journal: |
PLoS One |
Title: |
Deterministic and stochastic allele specific gene expression in single mouse blastomeres. |
Volume: |
6 |
Issue: |
6 |
Pages: |
e21208 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Backcross DNA Panel Mapping Resource |
Year: |
1999 |
Journal: |
Database Release |
Title: |
JAX BSS Panel Mapping Data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2001 |
|
Title: |
RIKEN Data Curation in Mouse Genome Informatics |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2001 |
|
Title: |
Gene Ontology Annotation by the MGI Curatorial Staff |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators, MGI curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation based on Enzyme Commission mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen J |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
Volume: |
100 |
Issue: |
17 |
Pages: |
9918-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2016 |
|
Title: |
Automatic assignment of GO terms using logical inference, based on on inter-ontology links |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
HT Experiment |
Series Id: |
E-GEOD-77482 |
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
HT Experiment |
|
Experiment Type: |
RNA-Seq |
Study Type: |
WT vs. Mutant |
Source: |
GEO |
|
•
•
•
•
•
|
Publication |
First Author: |
Koikawa K |
Year: |
2021 |
Journal: |
Cell |
Title: |
Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy. |
Volume: |
184 |
Issue: |
18 |
Pages: |
4753-4771.e27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakatsu Y |
Year: |
2020 |
Journal: |
Cancer Lett |
Title: |
Prolyl isomerase Pin1 in metabolic reprogramming of cancer cells. |
Volume: |
470 |
|
Pages: |
106-114 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
165
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Baquero J |
Year: |
2019 |
Journal: |
Front Mol Neurosci |
Title: |
Nuclear Tau, p53 and Pin1 Regulate PARN-Mediated Deadenylation and Gene Expression. |
Volume: |
12 |
|
Pages: |
242 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barone MC |
Year: |
2008 |
Journal: |
J Neurochem |
Title: |
Pin1 promotes cell death in NGF-dependent neurons through a mechanism requiring c-Jun activity. |
Volume: |
106 |
Issue: |
2 |
Pages: |
734-45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ueberham U |
Year: |
2014 |
Journal: |
Neuropathol Appl Neurobiol |
Title: |
Pin1 promotes degradation of Smad proteins and their interaction with phosphorylated tau in Alzheimer's disease. |
Volume: |
40 |
Issue: |
7 |
Pages: |
815-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yunokuchi I |
Year: |
2009 |
Journal: |
Genes Cells |
Title: |
Prolyl isomerase Pin1 shares functional similarity with phosphorylated CTD interacting factor PCIF1 in vertebrate cells. |
Volume: |
14 |
Issue: |
9 |
Pages: |
1105-18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Viswakarma N |
Year: |
2021 |
Journal: |
Cancer Lett |
Title: |
Mixed Lineage Kinase 3 phosphorylates prolyl-isomerase PIN1 and potentiates GLI1 signaling in pancreatic cancer development. |
Volume: |
515 |
|
Pages: |
1-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Driver JA |
Year: |
2015 |
Journal: |
Biochim Biophys Acta |
Title: |
Pin1 dysregulation helps to explain the inverse association between cancer and Alzheimer's disease. |
Volume: |
1850 |
Issue: |
10 |
Pages: |
2069-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wei S |
Year: |
2015 |
Journal: |
Nat Med |
Title: |
Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer. |
Volume: |
21 |
Issue: |
5 |
Pages: |
457-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bernardini A |
Year: |
2020 |
Journal: |
Am J Physiol Cell Physiol |
Title: |
Carotid body type I cells engage flavoprotein and Pin1 for oxygen sensing. |
Volume: |
318 |
Issue: |
4 |
Pages: |
C719-C731 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zheng Y |
Year: |
2011 |
Journal: |
Mol Cell Biol |
Title: |
Ras-induced and extracellular signal-regulated kinase 1 and 2 phosphorylation-dependent isomerization of protein tyrosine phosphatase (PTP)-PEST by PIN1 promotes FAK dephosphorylation by PTP-PEST. |
Volume: |
31 |
Issue: |
21 |
Pages: |
4258-69 |
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
Cdk2 and Pin1 negatively regulate the transcriptional corepressor SMRT. |
|
•
•
•
•
•
|
Publication |
First Author: |
Pan CQ |
Year: |
2010 |
Journal: |
J Cell Sci |
Title: |
Active Mek2 as a regulatory scaffold that promotes Pin1 binding to BPGAP1 to suppress BPGAP1-induced acute Erk activation and cell migration. |
Volume: |
123 |
Issue: |
Pt 6 |
Pages: |
903-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hou H |
Year: |
2010 |
Journal: |
Plant J |
Title: |
FORKED1 encodes a PH domain protein that is required for PIN1 localization in developing leaf veins. |
Volume: |
63 |
Issue: |
6 |
Pages: |
960-73 |
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
Opposite regulation of oligodendrocyte apoptosis by JNK3 and Pin1 after spinal cord injury. |
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
Pin1 catalyzes conformational changes of Thr-187 in p27Kip1 and mediates its stability through a polyubiquitination process. |
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
Pin1 facilitates the phosphorylation-dependent ubiquitination of SF-1 to regulate gonadotropin beta-subunit gene transcription. |
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
Negative Regulation of the Stability and Tumor Suppressor Function of Fbw7 by the Pin1 Prolyl Isomerase. |
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
Essential role for the prolyl isomerase Pin1 in Toll-like receptor signaling and type I interferon-mediated immunity. |
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
Pin1 interacts with c-Myb in a phosphorylation-dependent manner and regulates its transactivation activity. |
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
Isomerase Pin1 stimulates dephosphorylation of tau protein at cyclin-dependent kinase (Cdk5)-dependent Alzheimer phosphorylation sites. |
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
Down-regulation of Pin1 in Temporal Lobe Epilepsy Patients and Mouse Model. |
|
•
•
•
•
•
|
Publication |
First Author: |
Kops O |
Year: |
2002 |
Journal: |
FEBS Lett |
Title: |
Pin1 modulates the dephosphorylation of the RNA polymerase II C-terminal domain by yeast Fcp1. |
Volume: |
513 |
Issue: |
2-3 |
Pages: |
305-11 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1774
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1734
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1348
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1762
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
Prolyl isomerase Pin1 and protein kinase HIPK2 cooperate to promote cortical neurogenesis by suppressing Groucho/TLE:Hes1-mediated inhibition of neuronal differentiation. |
|
•
•
•
•
•
|
Publication |
First Author: |
Tejos R |
Year: |
2018 |
Journal: |
J Cell Sci |
Title: |
PATELLINS are regulators of auxin-mediated PIN1 relocation and plant development in Arabidopsis thaliana. |
Volume: |
131 |
Issue: |
2 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Li QM |
Year: |
2007 |
Journal: |
J Neurosci |
Title: |
Opposite regulation of oligodendrocyte apoptosis by JNK3 and Pin1 after spinal cord injury. |
Volume: |
27 |
Issue: |
31 |
Pages: |
8395-404 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pani E |
Year: |
2008 |
Journal: |
Biochim Biophys Acta |
Title: |
Pin1 interacts with c-Myb in a phosphorylation-dependent manner and regulates its transactivation activity. |
Volume: |
1783 |
Issue: |
6 |
Pages: |
1121-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tang L |
Year: |
2017 |
Journal: |
Neurochem Res |
Title: |
Down-regulation of Pin1 in Temporal Lobe Epilepsy Patients and Mouse Model. |
Volume: |
42 |
Issue: |
4 |
Pages: |
1211-1218 |
|
•
•
•
•
•
|
Publication |
First Author: |
Helander S |
Year: |
2015 |
Journal: |
Structure |
Title: |
Pre-Anchoring of Pin1 to Unphosphorylated c-Myc in a Fuzzy Complex Regulates c-Myc Activity. |
Volume: |
23 |
Issue: |
12 |
Pages: |
2267-79 |
|
•
•
•
•
•
|
Publication |
First Author: |
Khanal P |
Year: |
2012 |
Journal: |
Oncogene |
Title: |
Proyl isomerase Pin1 facilitates ubiquitin-mediated degradation of cyclin-dependent kinase 10 to induce tamoxifen resistance in breast cancer cells. |
Volume: |
31 |
Issue: |
34 |
Pages: |
3845-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Prabhakaran Mariyamma N |
Year: |
2017 |
Journal: |
J Exp Bot |
Title: |
Localization of Arabidopsis FORKED1 to a RABA-positive compartment suggests a role in secretion. |
Volume: |
68 |
Issue: |
13 |
Pages: |
3375-3390 |
|
•
•
•
•
•
|
Publication |
First Author: |
Naramoto S |
Year: |
2009 |
Journal: |
Development |
Title: |
Phosphoinositide-dependent regulation of VAN3 ARF-GAP localization and activity essential for vascular tissue continuity in plants. |
Volume: |
136 |
Issue: |
9 |
Pages: |
1529-38 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents a group of plant proteins, including VAN3-binding protein (VAB, also known as FORKED1 or AT3G63300) from Arabidopsis. FORKED1 is a PH domain protein required for PIN1 localization in developing leaf veins []. It interacts with SCARFACE/VAN3 (SFC), an ADP ribosylation factor GTPase-activating protein (ARF-GAP) important for vein patterning [, ]. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This domain describes a pleckstrin homology (PH)-like region found in several plant proteins, including VAN3-binding protein from Arabidopsis thaliana (also known as FORKED1), a component of the auto-regulatory loop which enables auxin canalisation by recruitment of the PIN1 auxin efflux protein to the cell membrane []. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This domain can be found at the N-terminal end of several plant proteins, including VAN3-binding protein from Arabidopsis thaliana (also known as FORKED1), a component of the auto-regulatory loop which enables auxin canalisation by recruitment of the PIN1 auxin efflux protein to the cell membrane []. This domain is frequently found on proteins containing at the C terminus. |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
59
 |
Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
37
 |
Fragment?: |
false |
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Publication |
First Author: |
Vogtherr M |
Year: |
2002 |
Journal: |
J Mol Biol |
Title: |
NMR solution structure and dynamics of the peptidyl-prolyl cis-trans isomerase domain of the trigger factor from Mycoplasma genitalium compared to FK506-binding protein. |
Volume: |
318 |
Issue: |
4 |
Pages: |
1097-115 |
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Publication |
First Author: |
Kühlewein A |
Year: |
2004 |
Journal: |
Protein Sci |
Title: |
Solution structure of Escherichia coli Par10: The prototypic member of the Parvulin family of peptidyl-prolyl cis/trans isomerases. |
Volume: |
13 |
Issue: |
9 |
Pages: |
2378-87 |
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Publication |
First Author: |
Saul FA |
Year: |
2004 |
Journal: |
J Mol Biol |
Title: |
Structural and functional studies of FkpA from Escherichia coli, a cis/trans peptidyl-prolyl isomerase with chaperone activity. |
Volume: |
335 |
Issue: |
2 |
Pages: |
595-608 |
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Protein Domain |
Type: |
Homologous_superfamily |
Description: |
This superfamily represents the peptidyl-prolyl cis-trans isomerase domain found in a wide range of proteins, including trigger factor [, ], FK506-binding proteins [, ], proteins from the parvulin family such as Par10 from E.coli, Pin1 and Par14 from human or Pin from plants [], chaperone SurA [, ]and foldase protein PrsA []. This domain catalyses cis/trans isomerization of peptidyl-prolyl bonds, which is often rate-limiting for protein folding.This domain consists of a flattened β-barrel of four/six-stranded, antiparallel sheets, surrounded by four/six α-helices. |
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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