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Search results 201 to 285 out of 285 for Pkhd1

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Type Details Score
Publication
- | J:104190
     
First Author: The Australian Phenomics Facility at The Australian National University
Year: 2006
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University
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Publication
16919269 | J:112701
First Author: Bailey PJ
Year: 2006
Journal: Exp Cell Res
Title: A global genomic transcriptional code associated with CNS-expressed genes.
Volume: 312
Issue: 16
Pages: 3108-19
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Gene
100486760 | pkhd1l1
Type: gene
Organism: frog, western clawed
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Gene
569167 | pkhd1l1.2
Type: gene
Organism: zebrafish
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Gene
569261 | pkhd1l1.1
Type: gene
Organism: zebrafish
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Gene
108719383 | pkhd1l1.L
Type: gene
Organism: frog, African clawed
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Interaction Experiment
Hiesberger T (2005)
Description: Role of the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal domain in Pkhd1 (ARPKD) gene transcription and renal cystogenesis.
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Allele
Tg(Pkhd1-cre)1Igr | MGI:3794109
Name: transgene insertion 1, Peter Igarashi
Allele Type: Transgenic
Attribute String: Recombinase
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Protein
A0A494BB04
Organism: Mus musculus/domesticus
Length: 194  
Fragment?: true
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Protein Domain
IPR019316 | G8_domain
Type: Domain
Description: This entry represents a domain found in disease proteins PKHD1 and KIAA1199 and is named G8 after its 8 conserved glycines. It is predicted to contain 10 beta strands and an alpha helix [].
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Publication
31064883 | J:281841
 
First Author: Kuo IY
Year: 2019
Journal: Sci Signal
Title: Polycystin 2 regulates mitochondrial Ca2+ signaling, bioenergetics, and dynamics through mitofusin 2.
Volume: 12
Issue: 580
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Genotype
Genotype
Symbol: Pkd2/Pkd2 Tg(Pkhd1-cre)1Igr/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pkd2/Pkd2 Tg(Pkhd1-cre)1Igr/?
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pkd2/Pkd2 Tg(Pkhd1-cre)1Igr/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Pkhd1-cre)1Igr/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pkd2/Pkd2 Tg(Pkhd1-cre)1Igr/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
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Publication
16632497 | -
First Author: He QY
Year: 2006
Journal: Bioinformatics
Title: G8: a novel domain associated with polycystic kidney disease and non-syndromic hearing loss.
Volume: 22
Issue: 18
Pages: 2189-91
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Publication
28522687 | J:291498
First Author: Raman A
Year: 2017
Journal: J Am Soc Nephrol
Title: Integrin-Linked Kinase Signaling Promotes Cyst Growth and Fibrosis in Polycystic Kidney Disease.
Volume: 28
Issue: 9
Pages: 2708-2719
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Genotype
Genotype
Symbol: Mirc1/Mirc1 Pkd2/Pkd2 Tg(Pkhd1-cre)1Igr/?
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mir214/Mir214 Pkd2/Pkd2 Tg(Pkhd1-cre)1Igr/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
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Publication
29042084 | J:277063
First Author: Wang Q
Year: 2018
Journal: Kidney Int
Title: Adenylyl cyclase 5 deficiency reduces renal cyclic AMP and cyst growth in an orthologous mouse model of polycystic kidney disease.
Volume: 93
Issue: 2
Pages: 403-415
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Publication
25877301 | J:223341
First Author: Zhou X
Year: 2015
Journal: Hum Mol Genet
Title: Therapeutic targeting of BET bromodomain protein, Brd4, delays cyst growth in ADPKD.
Volume: 24
Issue: 14
Pages: 3982-93
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Publication
30280600 | J:283229
First Author: Trott JF
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Arginine reprogramming in ADPKD results in arginine-dependent cystogenesis.
Volume: 315
Issue: 6
Pages: F1855-F1868
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Publication
36611841 | J:352057
 
First Author: Li LX
Year: 2022
Journal: Cells
Title: Single-Cell and CellChat Resolution Identifies Collecting Duct Cell Subsets and Their Communications with Adjacent Cells in PKD Kidneys.
Volume: 12
Issue: 1
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Publication
19966229 | J:155816
First Author: Cao Y
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models.
Volume: 106
Issue: 51
Pages: 21819-24
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Genotype
Genotype
Symbol: Pkd1/Pkd1 Tg(Pkhd1-cre)1Igr/?
Background: involves: C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pkd2/Pkd2 Tg(Pkd1)248Som/? Tg(Pkhd1-cre)1Igr/?
Background: involves: C57BL/6J * SJL/J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mir21a/Mir21a Pkd2/Pkd2 Tg(Pkhd1-cre)1Igr/?
Background: involves: 129S/SvEv
Zygosity: cn
Has Mutant Allele: true
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Publication
34345895 | J:327006
 
First Author: Grosch M
Year: 2021
Journal: J Cell Sci
Title: A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts.
Volume: 134
Issue: 16
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Publication
28507058 | J:290181
First Author: Aboudehen K
Year: 2017
Journal: J Am Soc Nephrol
Title: Hepatocyte Nuclear Factor-1β Regulates Urinary Concentration and Response to Hypertonicity.
Volume: 28
Issue: 10
Pages: 2887-2900
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Publication
29716997 | J:263878
First Author: Aboudehen K
Year: 2018
Journal: J Biol Chem
Title: Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling.
Volume: 293
Issue: 24
Pages: 9388-9398
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Publication
28615245 | J:281864
First Author: Ye H
Year: 2017
Journal: Am J Physiol Renal Physiol
Title: The regulatory 1α subunit of protein kinase A modulates renal cystogenesis.
Volume: 313
Issue: 3
Pages: F677-F686
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Genotype
Genotype
Symbol: Hoxb3os/Hoxb3os Pkd1/Pkd1 Tg(Pkhd1-cre)1Igr/?
Background: involves: 129S4/SvJae * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Publication
28375157 | J:269547
First Author: Besse W
Year: 2017
Journal: J Clin Invest
Title: Isolated polycystic liver disease genes define effectors of polycystin-1 function.
Volume: 127
Issue: 5
Pages: 1772-1785
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Publication
12620974 | J:82450
First Author: Hogan MC
Year: 2003
Journal: Hum Mol Genet
Title: PKHDL1, a homolog of the autosomal recessive polycystic kidney disease gene, encodes a receptor with inducible T lymphocyte expression.
Volume: 12
Issue: 6
Pages: 685-98
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Publication
15029248 | J:131271
First Author: Gresh L
Year: 2004
Journal: EMBO J
Title: A transcriptional network in polycystic kidney disease.
Volume: 23
Issue: 7
Pages: 1657-68
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Publication
36503993 | J:338389
First Author: Belyea BC
Year: 2023
Journal: Clin Sci (Lond)
Title: Overexpression of notch signaling in renin cells leads to a polycystic kidney phenotype.
Volume: 137
Issue: 1
Pages: 35-45
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Publication
32182218 | J:306875
 
First Author: Lakhia R
Year: 2020
Journal: JCI Insight
Title: Interstitial microRNA miR-214 attenuates inflammation and polycystic kidney disease progression.
Volume: 5
Issue: 7
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Publication
31601454 | J:297942
First Author: Ferrè S
Year: 2019
Journal: Kidney Int
Title: Renal tubular cell spliced X-box binding protein 1 (Xbp1s) has a unique role in sepsis-induced acute kidney injury and inflammation.
Volume: 96
Issue: 6
Pages: 1359-1373
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Publication
25961459 | J:222949
First Author: Chen L
Year: 2015
Journal: J Clin Invest
Title: Macrophage migration inhibitory factor promotes cyst growth in polycystic kidney disease.
Volume: 125
Issue: 6
Pages: 2399-412
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Publication
29483507 | J:259698
First Author: Flowers EM
Year: 2018
Journal: Nat Commun
Title: Lkb1 deficiency confers glutamine dependency in polycystic kidney disease.
Volume: 9
Issue: 1
Pages: 814
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Publication
25365220 | J:219409
First Author: Cai Y
Year: 2014
Journal: J Clin Invest
Title: Altered trafficking and stability of polycystins underlie polycystic kidney disease.
Volume: 124
Issue: 12
Pages: 5129-44
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Publication
30745418 | J:293109
     
First Author: Ishikawa Y
Year: 2019
Journal: J Am Soc Nephrol
Title: Spliced XBP1 Rescues Renal Interstitial Inflammation Due to Loss of Sec63 in Collecting Ducts.
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kif3a/Kif3a<+> Tg(Pkhd1-cre)1Igr/?
Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Protein
Q5FWI3
Organism: Mus musculus/domesticus
Length: 1383  
Fragment?: false
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Protein
Q8BI06
Organism: Mus musculus/domesticus
Length: 1361  
Fragment?: false
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Protein
Q14AX8
Organism: Mus musculus/domesticus
Length: 1361  
Fragment?: false
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Publication
28205547 | J:244067
 
First Author: Hajarnis S
Year: 2017
Journal: Nat Commun
Title: microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism.
Volume: 8
Pages: 14395
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Publication
33046531 | J:338058
First Author: Zhang C
Year: 2021
Journal: J Am Soc Nephrol
Title: Cyclin-Dependent Kinase 1 Activity Is a Driver of Cyst Growth in Polycystic Kidney Disease.
Volume: 32
Issue: 1
Pages: 41-51
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Publication
29021386 | J:286965
First Author: Hajarnis S
Year: 2018
Journal: J Am Soc Nephrol
Title: Suppression of microRNA Activity in Kidney Collecting Ducts Induces Partial Loss of Epithelial Phenotype and Renal Fibrosis.
Volume: 29
Issue: 2
Pages: 518-531
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Publication
37953472 | J:345935
First Author: Weisser I
Year: 2024
Journal: J Am Soc Nephrol
Title: Ablation of Long Noncoding RNA Hoxb3os Exacerbates Cystogenesis in Mouse Polycystic Kidney Disease.
Volume: 35
Issue: 1
Pages: 41-55
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kif3a/Kif3a Tg(Pkhd1-cre)1Igr/?
Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Publication
26677864 | J:243677
First Author: Lakhia R
Year: 2016
Journal: J Am Soc Nephrol
Title: MicroRNA-21 Aggravates Cyst Growth in a Model of Polycystic Kidney Disease.
Volume: 27
Issue: 8
Pages: 2319-30
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Publication
18263604 | J:135301
First Author: Shibazaki S
Year: 2008
Journal: Hum Mol Genet
Title: Cyst formation and activation of the extracellular regulated kinase pathway after kidney specific inactivation of Pkd1.
Volume: 17
Issue: 11
Pages: 1505-16
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Publication
18263895 | J:135523
First Author: Patel V
Year: 2008
Journal: Hum Mol Genet
Title: Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia.
Volume: 17
Issue: 11
Pages: 1578-90
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Publication
36920028 | J:337850
   
First Author: Li Y
Year: 2023
Journal: Elife
Title: Inactivation of Invs/Nphp2 in renal epithelial cells drives infantile nephronophthisis like phenotypes in mouse.
Volume: 12
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Publication
23892607 | J:205308
First Author: Ma M
Year: 2013
Journal: Nat Genet
Title: Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease.
Volume: 45
Issue: 9
Pages: 1004-12
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Protein
Q80ZA4
Organism: Mus musculus/domesticus
Length: 4249  
Fragment?: false
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Protein
F8WH29
Organism: Mus musculus/domesticus
Length: 4247  
Fragment?: false
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Protein
E9PUU8
Organism: Mus musculus/domesticus
Length: 4249  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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