Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:3724788 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757722 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:5421441 |
Age: |
embryonic day 14.5 |
Image: |
MH1218; Specimen C1596 |
|
Specimen Label: |
MH1218; Specimen C1596 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3724788 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757522 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5421441 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
MH1218; Specimen C1596 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3724788 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1738322 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:5421441 |
Age: |
embryonic day 14.5 |
Image: |
MH1218; Specimen C1596 |
|
Specimen Label: |
MH1218; Specimen C1596 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3724788 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1802422 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5421441 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
MH1218; Specimen C1596 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3724788 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1768022 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5421441 |
Age: |
embryonic day 14.5 |
|
Note: |
Expression was not detected in the skull (base and vault). |
Specimen Label: |
MH1218; Specimen C1596 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423782 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1791823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827232 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009487_08 |
|
Specimen Label: |
euxassay_009487_08 |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423782 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1791823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827232 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009487_11 |
|
Specimen Label: |
euxassay_009487_11 |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423782 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1791823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4827232 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009487_12 |
|
Specimen Label: |
euxassay_009487_12 |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3724788 |
Assay Type: |
RNA in situ |
Annotation Date: |
2012-06-12 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:2672022 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:5421441 |
Age: |
embryonic day 14.5 |
Image: |
MH1218; Specimen C1596 |
Note: |
Expression was weak in whisker follicle. |
Specimen Label: |
MH1218; Specimen C1596 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
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Pyruvate kinase PKLR |
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
574
 |
Fragment?: |
false |
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•
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Allele |
Name: |
pyruvate kinase liver and red blood cell; endonuclease-mediated mutation 1, Applied StemCell |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Modified isoform(s), Null/knockout |
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•
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Allele |
Name: |
pyruvate kinase liver and red blood cell; pyruvate kinase deficiency |
Allele Type: |
Spontaneous |
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•
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Genotype |
Symbol: |
Pklr/Pklr |
Background: |
CBA/NSlc-Pklr |
Zygosity: |
hm |
Has Mutant Allele: |
true |
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DO Term |
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Allele |
Name: |
pyruvate kinase liver and red blood cell; char4 |
Allele Type: |
Spontaneous |
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•
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Allele |
Name: |
transgene insertion, Axel Kahn |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
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•
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•
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Allele |
Name: |
transgene insertion B, Axel Kahn |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
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•
•
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•
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Allele |
Name: |
pyruvate kinase liver and red blood cell; endonuclease-mediated mutation 1, Hao Zhu |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Inducible, Recombinase |
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•
•
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•
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Genotype |
Symbol: |
Pklr/Pklr |
Background: |
involves: A/J * C57BL/6 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
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•
•
•
•
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Publication |
First Author: |
Mitchell C |
Year: |
2009 |
Journal: |
Am J Pathol |
Title: |
Protection against hepatocyte mitochondrial dysfunction delays fibrosis progression in mice. |
Volume: |
175 |
Issue: |
5 |
Pages: |
1929-37 |
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Strain |
Attribute String: |
transgenic, mutant strain, congenic |
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Publication |
First Author: |
Mignon A |
Year: |
1998 |
Journal: |
Nat Med |
Title: |
Selective repopulation of normal mouse liver by Fas/CD95-resistant hepatocytes. |
Volume: |
4 |
Issue: |
10 |
Pages: |
1185-8 |
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•
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Publication |
First Author: |
Peralta C |
Year: |
2002 |
Journal: |
Am J Pathol |
Title: |
The combination of ischemic preconditioning and liver Bcl-2 overexpression is a suitable strategy to prevent liver and lung damage after hepatic ischemia-reperfusion. |
Volume: |
160 |
Issue: |
6 |
Pages: |
2111-22 |
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•
•
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Publication |
First Author: |
Mitchell C |
Year: |
2011 |
Journal: |
Lab Invest |
Title: |
Overexpression of Bcl-2 in hepatocytes protects against injury but does not attenuate fibrosis in a mouse model of chronic cholestatic liver disease. |
Volume: |
91 |
Issue: |
2 |
Pages: |
273-82 |
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•
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•
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Publication |
First Author: |
Mallet VO |
Year: |
2002 |
Journal: |
Hepatology |
Title: |
Bone marrow transplantation in mice leads to a minor population of hepatocytes that can be selectively amplified in vivo. |
Volume: |
35 |
Issue: |
4 |
Pages: |
799-804 |
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•
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•
•
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Allele |
Name: |
transgene insertion 1, Axel Kahn |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
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•
•
•
•
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Allele |
Name: |
transgene insertion 23, Axel Kahn |
Allele Type: |
Transgenic |
Attribute String: |
Constitutively active, Inserted expressed sequence |
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•
•
•
•
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Allele |
Name: |
transgene insertion 21, Axel Kahn |
Allele Type: |
Transgenic |
Attribute String: |
Constitutively active, Inserted expressed sequence |
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•
•
•
•
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Allele |
Name: |
transgene insertion 73, Axel Kahn |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
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•
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•
•
•
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Genotype |
Symbol: |
Tg(Pklr-SV40)1Ak/? |
Background: |
involves: C57BL/6 * DBA |
Zygosity: |
ot |
Has Mutant Allele: |
true |
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•
•
•
•
•
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Genotype |
Symbol: |
Tg(Pklr-SV40)1Ak/Tg(Pklr-SV40)1Ak |
Background: |
involves: C57BL/6 * DBA |
Zygosity: |
hm |
Has Mutant Allele: |
true |
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•
•
•
•
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Publication |
First Author: |
Zhou X |
Year: |
2021 |
Journal: |
Hum Mol Genet |
Title: |
Coordinated pyruvate kinase activity is crucial for metabolic adaptation and cell survival during mitochondrial dysfunction. |
Volume: |
30 |
Issue: |
21 |
Pages: |
2012-2026 |
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•
•
•
•
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Publication |
First Author: |
Chella Krishnan K |
Year: |
2018 |
Journal: |
Cell Syst |
Title: |
Integration of Multi-omics Data from Mouse Diversity Panel Highlights Mitochondrial Dysfunction in Non-alcoholic Fatty Liver Disease. |
Volume: |
6 |
Issue: |
1 |
Pages: |
103-115.e7 |
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•
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•
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Publication |
First Author: |
Mizushima T |
Year: |
2013 |
Journal: |
Am J Pathol |
Title: |
Inhibition of epithelial cell death by Bcl-2 improved chronic colitis in IL-10 KO mice. |
Volume: |
183 |
Issue: |
6 |
Pages: |
1936-44 |
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