|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 201 to 300 out of 319 for Pms2

<< First    < Previous  |  Next >    Last >>
0.026s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
9192668 | J:41499
First Author: Mizuta R
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: RAB22 and RAB163/mouse BRCA2: proteins that specifically interact with the RAD51 protein.
Volume: 94
Issue: 13
Pages: 6927-32
•
•
•
•
•
Publication
16260499 | J:104493
First Author: Kolas NK
Year: 2005
Journal: J Cell Biol
Title: Localization of MMR proteins on meiotic chromosomes in mice indicates distinct functions during prophase I.
Volume: 171
Issue: 3
Pages: 447-58
•
•
•
•
•
Publication
10809667 | J:62204
First Author: Kneitz B
Year: 2000
Journal: Genes Dev
Title: MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice.
Volume: 14
Issue: 9
Pages: 1085-97
•
•
•
•
•
Publication
21062905 | J:220439
First Author: McLachlan S
Year: 2011
Journal: Physiol Genomics
Title: In silico QTL mapping of basal liver iron levels in inbred mouse strains.
Volume: 43
Issue: 3
Pages: 136-47
•
•
•
•
•
Publication
23920106 | J:202864
First Author: Keil KP
Year: 2013
Journal: Gene Expr Patterns
Title: Catalog of mRNA expression patterns for DNA methylating and demethylating genes in developing mouse lower urinary tract.
Volume: 13
Issue: 8
Pages: 413-24
•
•
•
•
•
Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
•
•
•
•
•
Publication
15226823 | J:93300
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
•
•
•
•
•
Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
•
•
•
•
•
Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
•
•
•
•
•
Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
•
•
•
•
•
Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
•
•
•
•
•
Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
•
•
•
•
•
Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
•
•
•
•
•
Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
•
•
•
•
•
Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
•
•
•
•
•
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
•
•
•
•
•
Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
•
•
•
•
•
Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
•
•
•
•
•
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
•
•
•
•
•
Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
•
•
•
•
•
Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
•
•
•
•
•
Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
•
•
•
•
•
Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
•
•
•
•
•
Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
•
•
•
•
•
Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
•
•
•
•
•
Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
•
•
•
•
•
Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
•
•
•
•
•
Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
•
•
•
•
•
Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
UniProt Feature
UniProt Feature
Begin: 1
Description: Mismatch repair endonuclease PMS2
Type: chain
End: 859
•
•
•
•
•
Publication
- | J:152364
     
First Author: Drozdowski B
Year: 2009
Journal: MGI Direct Data Submission
Title: Generation of a dominant-negative PMS2 transgenic mouse line
•
•
•
•
•
Protein
E9QLM4
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
•
•
•
•
•
Protein
F6TK25
Organism: Mus musculus/domesticus
Length: 173  
Fragment?: true
•
•
•
•
•
HT Experiment
GSE237577 | Transcriptional profiling of cortex from a mouse model of Huntington's disease (Q140) crossed with Pms2 heterozygous and homozygous mice [Pms2]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
•
•
•
•
•
HT Experiment
GSE237584 | Transcriptional profiling of striatum from a mouse model of Huntington's disease (Q140) crossed with Pms2 heterozygous and homozygous mice [Pms2_striatum]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
•
•
•
•
•
DO Term
DOID:0070275 | hereditary nonpolyposis colorectal cancer type 4
•
•
•
•
•
Gene
7027 | TFDP1
Type: gene
Organism: human
•
•
•
•
•
Allele
Pms2<em1Smoc> | MGI:7291738
Name: PMS1 homolog2, mismatch repair system component; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Gene
9014 | TAF1B
Type: gene
Organism: human
•
•
•
•
•
Gene
114571 | SLC22A9
Type: gene
Organism: human
•
•
•
•
•
Gene
28990 | ASTE1
Type: gene
Organism: human
•
•
•
•
•
Strain
MGI:6429381 | C57BL/6JSmoc-Pms2<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
•
•
•
•
•
Gene
5426 | POLE
Type: gene
Organism: human
•
•
•
•
•
DO Term
DOID:0112182 | mismatch repair cancer syndrome
•
•
•
•
•
Gene
2956 | MSH6
Type: gene
Organism: human
•
•
•
•
•
Allele
Tg(EIF1AX-PMS2*)685Tcar | MGI:4357948
Name: transgene insertion 685, Trent Carrier
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
Strain
MGI:4358208 | B6;SJL-Tg(EIF1AX-PMS2*)685Tcar/J
Attribute String: mutant stock, transgenic
•
•
•
•
•
Publication
16382047 | J:152366
 
First Author: Nicolaides NC
Year: 2005
Journal: Ann N Y Acad Sci
Title: Morphogenics as a tool for target discovery and drug development.
Volume: 1059
Pages: 86-96
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(EIF1AX-PMS2*)685Tcar/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
•
•
•
•
•
Gene
8635 | RNASET2
Type: gene
Organism: human
•
•
•
•
•
Gene
7048 | TGFBR2
Type: gene
Organism: human
•
•
•
•
•
Gene
4436 | MSH2
Type: gene
Organism: human
•
•
•
•
•
Gene
4292 | MLH1
Type: gene
Organism: human
•
•
•
•
•
Allele
Pms2<tm2(cre)Lisk> | MGI:5538273
Name: PMS1 homolog2, mismatch repair system component; targeted mutation 2, Michael Liskay
Allele Type: Targeted
Attribute String: Recombinase
•
•
•
•
•
Genotype
Genotype
Symbol: Tg(EIF1AX-PMS2*)685Tcar/? Tg(TacLIZa)A1Jsh/?
Background: involves: C57BL/6 * SJL
Zygosity: cx
Has Mutant Allele: true
•
•
•
•
•
Publication
11717305 | -
First Author: Hall MC
Year: 2002
Journal: J Biol Chem
Title: Differential ATP binding and intrinsic ATP hydrolysis by amino-terminal domains of the yeast Mlh1 and Pms1 proteins.
Volume: 277
Issue: 5
Pages: 3673-9
•
•
•
•
•
Protein Domain
IPR038973 | MutL/Mlh/Pms
Type: Family
Description: Mismatch repair contributes to the overall fidelity of DNA replication by targeting mispaired bases that arise through replication errors during homologous recombination and as a result of DNA damage. It involves the correction of mismatched base pairs that have been missed by the proofreading element of the DNA polymerase complex []. This entry represents a family of evolutionarily related DNA mismatch repair proteins, including MutL, Mlh1, Mlh2 and Mlh3, and Pms 1 and 2. Bacterial MutL proteins are homodimers, while their eukaryotic homologues form heterodimers consisting of the MutL homologue Mlh1 and either Pms1, Pms2 or Mlh3 [, ]. MutL homologues share a conserved ATP binding site [].
•
•
•
•
•
Publication
8673133 | J:34291
First Author: Baker SM
Year: 1996
Journal: Nat Genet
Title: Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over.
Volume: 13
Issue: 3
Pages: 336-42
•
•
•
•
•
Genotype
Genotype
Symbol: Pms2/Pms2
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
•
•
•
•
•
Protein
D3YX04
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: true
•
•
•
•
•
Protein
Q9CTA7
Organism: Mus musculus/domesticus
Length: 419  
Fragment?: false
•
•
•
•
•
Protein
F6R1G0
Organism: Mus musculus/domesticus
Length: 94  
Fragment?: true
•
•
•
•
•
Protein
D3Z611
Organism: Mus musculus/domesticus
Length: 88  
Fragment?: true
•
•
•
•
•
Publication
16024043 | -
First Author: Kosinski J
Year: 2005
Journal: J Mol Biol
Title: Analysis of the quaternary structure of the MutL C-terminal domain.
Volume: 351
Issue: 4
Pages: 895-909
•
•
•
•
•
Publication
10946232 | -
First Author: Yang W
Year: 2000
Journal: Mutat Res
Title: Structure and function of mismatch repair proteins.
Volume: 460
Issue: 3-4
Pages: 245-56
•
•
•
•
•
Protein Domain
IPR002099 | DNA_mismatch_repair_N
Type: Domain
Description: This entry represents the N-terminal domain of DNA mismatch repair proteins, such asMutL. Bacterial MutL proteins are homodimers, while their eukaryotic homologues form heterodimers consisting of the MutL homologue Mlh1 and either Pms1, Pms2 or Mlh3 [, ]. MutL proteins and their homologues share sequence homology at their N termini over the first 300-400 residues; the C termini are less well conserved, they constitute the main dimerization domain and are required for interaction between MutL and UvrD helicase []. The activity of the protein is modulated by the ATP-dependent dimerization of the N-terminal domain [].The dimeric MutL protein has a key function in communicating mismatch recognition by MutS to downstream repair processes. Mismatch repair contributes to the overall fidelity of DNA replication by targeting mispaired bases that arise through replication errors during homologous recombination and as a result of DNA damage. It involves the correction of mismatched base pairs that have been missed by the proofreading element of the DNA polymerase complex [].
•
•
•
•
•
Publication
26436461 | -
 
First Author: Kunkel TA
Year: 2015
Journal: Annu Rev Genet
Title: Eukaryotic Mismatch Repair in Relation to DNA Replication.
Volume: 49
Pages: 291-313
•
•
•
•
•
Publication
10092760 | J:53460
First Author: Phung QH
Year: 1999
Journal: J Immunol
Title: Hypermutation in Ig V genes from mice deficient in the MLH1 mismatch repair protein.
Volume: 162
Issue: 6
Pages: 3121-4
•
•
•
•
•
Publication
10747038 | J:61445
First Author: Oda S
Year: 2000
Journal: EMBO J
Title: Efficient repair of A/C mismatches in mouse cells deficient in long-patch mismatch repair.
Volume: 19
Issue: 7
Pages: 1711-8
•
•
•
•
•
Publication
9110401 | J:40099
First Author: Prolla TA
Year: 1996
Journal: Semin Cancer Biol
Title: DNA mismatch repair deficient mice in cancer research.
Volume: 7
Issue: 5
Pages: 241-7
•
•
•
•
•
Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pms2/Pms2
Background: involves: 129S4/SvJaeSor
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pms2/Pms2<+>
Background: involves: 129S4/SvJaeSor
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Publication
14527292 | -
 
First Author: Schofield MJ
Year: 2003
Journal: Annu Rev Microbiol
Title: DNA mismatch repair: molecular mechanisms and biological function.
Volume: 57
Pages: 579-608
•
•
•
•
•
Publication
10570173 | -
First Author: Wang TF
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Functional specificity of MutL homologs in yeast: evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction.
Volume: 96
Issue: 24
Pages: 13914-9
•
•
•
•
•
Gene
7157 | TP53
Type: gene
Organism: human
•
•
•
•
•
Publication
9916805 | J:51921
First Author: Edelmann W
Year: 1999
Journal: Nat Genet
Title: Mammalian MutS homologue 5 is required for chromosome pairing in meiosis.
Volume: 21
Issue: 1
Pages: 123-7
•
•
•
•
•
Publication
12091911 | J:78200
First Author: Lipkin SM
Year: 2002
Journal: Nat Genet
Title: Meiotic arrest and aneuploidy in MLH3-deficient mice.
Volume: 31
Issue: 4
Pages: 385-90
•
•
•
•
•
Publication
19638594 | J:151771
First Author: Edwards RA
Year: 2009
Journal: Cancer Res
Title: Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer.
Volume: 69
Issue: 16
Pages: 6423-9
•
•
•
•
•
Publication
12175905 | J:85244
First Author: Hersh MN
Year: 2002
Journal: Mutat Res
Title: Visualization of mosaicism in tissues of normal and mismatch-repair-deficient mice carrying a microsatellite-containing transgene.
Volume: 505
Issue: 1-2
Pages: 51-62
•
•
•
•
•
Publication
10615123 | J:59324
First Author: Lipkin SM
Year: 2000
Journal: Nat Genet
Title: MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability.
Volume: 24
Issue: 1
Pages: 27-35
•
•
•
•
•
Publication
10498885 | J:58239
First Author: Heyer J
Year: 1999
Journal: Oncogene
Title: Mouse models for colorectal cancer.
Volume: 18
Issue: 38
Pages: 5325-33
•
•
•
•
•
Publication
12062055 | J:77402
First Author: Colussi C
Year: 2002
Journal: Curr Biol
Title: The mammalian mismatch repair pathway removes DNA 8-oxodGMP incorporated from the oxidized dNTP pool.
Volume: 12
Issue: 11
Pages: 912-8
•
•
•
•
•
Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kras/Kras<+> Pms2/Pms2
Background: involves: 129S4/SvJae * 129S4/SvJaeSor
Zygosity: cn
Has Mutant Allele: true
•
•
•
•
•
Protein
F6X8D5
Organism: Mus musculus/domesticus
Length: 166  
Fragment?: true
•
•
•
•
•
Protein
D3Z0R7
Organism: Mus musculus/domesticus
Length: 127  
Fragment?: true
•
•
•
•
•
Protein
Q9JK91
Organism: Mus musculus/domesticus
Length: 760  
Fragment?: false
•
•
•
•
•
Protein
Q8CAP8
Organism: Mus musculus/domesticus
Length: 653  
Fragment?: false
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom