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Search results 201 to 300 out of 5063 for Pole

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
GO Term
GO:0046594 | maintenance of pole plasm mRNA location
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GO Term
GO:0045451 | pole plasm oskar mRNA localization
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GO Term
GO:0034631 | microtubule anchoring at spindle pole body
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Protein Domain
IPR031392 | Spc29
Type: Family
Description: Spc29 is a component of the Spc-110 subcomplex and is required for the SPB (Spindle pole body) duplication. Spc29 acts as a linker between the central plaque component Spc42 to the inner plaque component Spc110 [].
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GO Term
GO:0019096 | pole plasm mitochondrial lrRNA localization
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GO Term
GO:0019095 | pole plasm mitochondrial rRNA localization
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GO Term
GO:0019097 | pole plasm mitochondrial srRNA localization
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GO Term
GO:0045495 | pole plasm
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GO Term
GO:0032121 | meiotic attachment of telomeric heterochromatin to spindle pole body
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GO Term
GO:0071990 | maintenance of protein location to spindle pole body
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GO Term
GO:1903087 | mitotic spindle pole body duplication
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GO Term
GO:0070057 | prospore membrane spindle pole body attachment site
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GO Term
GO:1990608 | mitotic spindle pole body localization
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GO Term
GO:1990901 | old cell pole
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GO Term
GO:1990902 | new cell pole
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Publication
28469279 | J:275317
First Author: Magescas J
Year: 2017
Journal: Sci Rep
Title: Spindle pole cohesion requires glycosylation-mediated localization of NuMA.
Volume: 7
Issue: 1
Pages: 1474
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GO Term
GO:1902440 | protein localization to mitotic spindle pole body
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GO Term
GO:1902441 | protein localization to meiotic spindle pole body
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Protein Domain
IPR021611 | Spc42
Type: Family
Description: Spc42 is a central plaque component of spindle pole body (SPB), which is the microtubule organising centre (MTOC) in the yeast Saccharomyces. Spc42 is involved in SPB duplication and facilitates the attachment of the SPB to the nuclear membrane [].
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UniProt Feature
UniProt Feature
Begin: 1
Description: Centrosome and spindle pole associated protein 1
Type: chain
End: 1205
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GO Term
GO:0051305 | chromosome movement towards spindle pole
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HT Sample
GSM5387089
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal day 56
Stage: 28
Structure . Name: prefrontal cortex
Notes: frontal pole cortex
Curation Status: Curated
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HT Sample
GSM5387090
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal day 56
Stage: 28
Structure . Name: prefrontal cortex
Notes: frontal pole cortex
Curation Status: Curated
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HT Sample
GSM5387091
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal day 56
Stage: 28
Structure . Name: prefrontal cortex
Notes: frontal pole cortex
Curation Status: Curated
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HT Sample
GSM5629175
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal adult
Stage: 28
Structure . Name: prefrontal cortex
Notes: primary motor/frontal pole
Curation Status: Curated
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Protein Domain
IPR029328 | Bbp1_N
Type: Domain
Description: This N-terminal domain of Bbp1, a spindle pole body component, interacts directly, though transiently, with the polo-box domain of Cdc5. Full length Bbp1 localises at the cytoplasmic side of the central plaque periphery of the spindle pole body (SPB) and plays an important role in inserting a duplication plaque into the nuclear envelope and assembling a functional inner plaque []. Although not a membrane protein itself, Bbp1 binds to Mps2 as well as to Spc29 and the half-bridge protein Kar1, thus providing a model for how the SPB core is tethered within the nuclear envelope and to the half-bridge [].
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Gene
315330 | Espl1
Type: gene
Organism: rat
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Gene
607879 | ESPL1
Type: gene
Organism: dog, domestic
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Gene
362472 | Cspp1
Type: gene
Organism: rat
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Gene
451937 | ESPL1
Type: gene
Organism: chimpanzee
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Gene
472785 | CSPP1
Type: gene
Organism: chimpanzee
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Gene
477902 | CSPP1
Type: gene
Organism: dog, domestic
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Gene
506740 | ESPL1
Type: gene
Organism: cattle
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Gene
524180 | CSPP1
Type: gene
Organism: cattle
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Gene
420169 | CSPP1
Type: gene
Organism: chicken
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Gene
425536 | ESPL1
Type: gene
Organism: chicken
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Gene
570598 | cspp1b
Type: gene
Organism: zebrafish
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Gene
797406 | espl1
Type: gene
Organism: zebrafish
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Gene
702136 | ESPL1
Type: gene
Organism: macaque, rhesus
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Gene
704476 | CSPP1
Type: gene
Organism: macaque, rhesus
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Gene
779552 | cspp1
Type: gene
Organism: frog, western clawed
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Gene
100158636 | espl1
Type: gene
Organism: frog, western clawed
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Gene
103909748 | cspp1
Type: gene
Organism: zebrafish
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Gene
431925 | espl1.S
Type: gene
Organism: frog, African clawed
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Gene
445837 | cspp1.L
Type: gene
Organism: frog, African clawed
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Gene
733221 | espl1.L
Type: gene
Organism: frog, African clawed
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GO Term
GO:0031616 | spindle pole centrosome
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GO Term
GO:1990735 | gamma-tubulin complex localization to mitotic spindle pole body
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Protein Coding Gene
MGI:2146156 | Espl1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
31895686 | J:294949
First Author: Wang X
Year: 2020
Journal: Reproduction
Title: CEP215 and AURKA regulate spindle pole focusing and aMTOC organization in mouse oocytes.
Volume: 159
Issue: 3
Pages: 261-274
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Publication
9531532 | -
First Author: Bridge AJ
Year: 1998
Journal: Genes Dev
Title: The fission yeast SPB component Cut12 links bipolar spindle formation to mitotic control.
Volume: 12
Issue: 7
Pages: 927-42
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Publication
12065422 | -
First Author: Grallert A
Year: 2002
Journal: EMBO J
Title: Schizosaccharomyces pombe NIMA-related kinase, Fin1, regulates spindle formation and an affinity of Polo for the SPB.
Volume: 21
Issue: 12
Pages: 3096-107
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Protein Domain
IPR021589 | Cut12
Type: Domain
Description: This is the central coiled-coil region of cut12 also found in other fungi, barring S. cerevisiae. The full protein has two predicted coiled-coil regions, and one consensus phosphorylation site for p34cdc2 and two for MAP kinase. During fission yeast mitosis, the duplicated spindle pole bodies (SPBs) nucleate microtubule arrays that interdigitate to form the mitotic spindle. Cut12 is localised to the SPB throughout the cell cycle, predominantly around the inner face of the interphase SPB, adjacent to the nucleus []. Cut12 associates with Fin1 and is important in this context for the activity of Plo1 [].
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GO Term
GO:0140480 | mitotic spindle pole body insertion into the nuclear envelope
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GO Term
GO:0031322 | ascospore-type prospore-specific spindle pole body remodeling
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GO Term
GO:0071957 | old mitotic spindle pole body
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Publication
11702954 | J:71788
First Author: Kelly RG
Year: 2001
Journal: Dev Cell
Title: The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm.
Volume: 1
Issue: 3
Pages: 435-40
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Publication
20890279 | J:166542
First Author: Nicholas AK
Year: 2010
Journal: Nat Genet
Title: WDR62 is associated with the spindle pole and is mutated in human microcephaly.
Volume: 42
Issue: 11
Pages: 1010-4
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Publication
35385691 | J:351903
First Author: Nikalayevich E
Year: 2022
Journal: Curr Biol
Title: Aurora B/C-dependent phosphorylation promotes Rec8 cleavage in mammalian oocytes.
Volume: 32
Issue: 10
Pages: 2281-2290.e4
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Protein
F6QJJ3
Organism: Mus musculus/domesticus
Length: 153  
Fragment?: true
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Protein
Q7TMJ9
Organism: Mus musculus/domesticus
Length: 477  
Fragment?: true
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Protein
A0A087WQ80
Organism: Mus musculus/domesticus
Length: 264  
Fragment?: true
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Protein
Q8C5S5
Organism: Mus musculus/domesticus
Length: 269  
Fragment?: false
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Publication
16826565 | -
First Author: Patzke S
Year: 2006
Journal: J Cell Physiol
Title: CSPP and CSPP-L associate with centrosomes and microtubules and differently affect microtubule organization.
Volume: 209
Issue: 1
Pages: 199-210
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Protein Domain
IPR026708 | CSPP1
Type: Family
Description: Centrosome and spindle pole associated protein 1 (CSPP) interacts with MyoGEF (a guanine nucleotide exchange factor that localises to the central spindle and cleavage furrow) and may play a role in cell-cycle-dependent microtubule organisation [, ].
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Protein Domain
IPR029330 | Bbp1_C
Type: Domain
Description: This C-terminal domain of Bbp1, a spindle pole body component, carries coiled-coils that are necessary for the localisation of Bbp1 to the spindle pole body (SPB) []. Although not a membrane protein itself, Bbp1 binds to Mps2 as well as to Spc29 and the half-bridge protein Kar1, thus providing a model for how the SPB core is tethered within the nuclear envelope and to the half-bridge [].
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GO Term
GO:0007277 | pole cell development
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Publication
10806191 | J:63658
First Author: Paine CT
Year: 2000
Journal: J Biol Chem
Title: A tuftelin-interacting protein (TIP39) localizes to the apical secretory pole of mouse ameloblasts.
Volume: 275
Issue: 29
Pages: 22284-92
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Publication
24069443 | J:206027
First Author: Shin H
Year: 2013
Journal: PLoS One
Title: The formin protein mDia2 serves as a marker of spindle pole dynamics in vitrified-warmed mouse oocytes.
Volume: 8
Issue: 9
Pages: e75729
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Publication
16709898 | J:122633
First Author: Christoffels VM
Year: 2006
Journal: Circ Res
Title: Formation of the venous pole of the heart from an Nkx2-5-negative precursor population requires Tbx18.
Volume: 98
Issue: 12
Pages: 1555-63
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Publication
27240320 | J:236813
First Author: van Ree JH
Year: 2016
Journal: Nat Cell Biol
Title: Pten regulates spindle pole movement through Dlg1-mediated recruitment of Eg5 to centrosomes.
Volume: 18
Issue: 7
Pages: 814-21
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GO Term
GO:0106212 | centromere detachment from spindle pole body involved in meiotic chromosome organization
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GO Term
GO:0005825 | half bridge of spindle pole body
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GO Term
GO:0016345 | female meiotic chromosome movement towards spindle pole
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GO Term
GO:0016346 | male meiotic chromosome movement towards spindle pole
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GO Term
GO:1902365 | positive regulation of protein localization to spindle pole body
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GO Term
GO:1902364 | negative regulation of protein localization to spindle pole body
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Publication
- | J:78216
   
First Author: Strausberg R
Year: 2002
Journal: GenBank Submission
Title: Mus musculus, similar to spindle pole body protein, clone IMAGE: 5324982, mRNA, partial cds
Pages: BC025647
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Protein Domain
IPR040593 | Spc110_C
Type: Domain
Description: This entry represents the C-terminal domain of Spc110 (spindle pole body component 110). Its N terminus is shown to bind to gamma-tubulin small complex (g-TuSC), while its C-terminal domain is essential for calmodulin-binding. The C terminus of Spc110 is anchored to the SPB via a conserved PACT domain [].
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GO Term
GO:0045856 | positive regulation of pole plasm oskar mRNA localization
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Publication
18832392 | J:143444
First Author: Park EJ
Year: 2008
Journal: Development
Title: An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart.
Volume: 135
Issue: 21
Pages: 3599-610
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Publication
39645657 | J:361364
First Author: Ma R
Year: 2024
Journal: Cell Rep
Title: Vimentin modulates regulatory T cell receptor-ligand interactions at distal pole complex, leading to dysregulated host response to viral pneumonia.
Volume: 43
Issue: 12
Pages: 115056
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GO Term
GO:0007278 | pole cell fate determination
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GO Term
GO:0071958 | new mitotic spindle pole body
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GO Term
GO:1902543 | negative regulation of protein localization to mitotic spindle pole body
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Publication
16030258 | J:106531
First Author: Huang X
Year: 2005
Journal: Mol Biol Cell
Title: Securin and separase phosphorylation act redundantly to maintain sister chromatid cohesion in mammalian cells.
Volume: 16
Issue: 10
Pages: 4725-32
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Publication
24680892 | J:212416
First Author: Thomas PS
Year: 2014
Journal: Dev Biol
Title: AcvR1-mediated BMP signaling in second heart field is required for arterial pole development: implications for myocardial differentiation and regional identity.
Volume: 390
Issue: 2
Pages: 191-207
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Publication
22855565 | J:212637
First Author: Lescroart F
Year: 2012
Journal: Circ Res
Title: Lineage tree for the venous pole of the heart: clonal analysis clarifies controversial genealogy based on genetic tracing.
Volume: 111
Issue: 10
Pages: 1313-22
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Publication
23284708 | -
First Author: Yong-Gonzales V
Year: 2012
Journal: PLoS One
Title: The Smc5-Smc6 complex regulates recombination at centromeric regions and affects kinetochore protein sumoylation during normal growth.
Volume: 7
Issue: 12
Pages: e51540
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Protein Domain
IPR031361 | Kre28
Type: Family
Description: S.cerevisiae Kre28 is asubunit of a kinetochore-microtubule binding complex that bridges centromeric heterochromatin and kinetochore MAPs and motors []. It may be regulated by sumoylation [].
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GO Term
GO:0000922 | spindle pole
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GO Term
GO:0060187 | cell pole
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GO Term
GO:0061493 | central plaque of mitotic spindle pole body
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GO Term
GO:0045855 | negative regulation of pole plasm oskar mRNA localization
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GO Term
GO:0016344 | meiotic chromosome movement towards spindle pole
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GO Term
GO:0007279 | pole cell formation
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GO Term
GO:0106084 | mitotic nuclear membrane microtubule tethering complex
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GO Term
GO:1905047 | mitotic spindle pole body organization
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GO Term
GO:0140475 | spindle pole body anchor activity
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GO Term
GO:1990395 | meiotic spindle pole body organization
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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