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Search results 201 to 216 out of 216 for Ppargc1b

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0.027s
Type Details Score
Publication      
First Author: Kelly DP
Year: 2010
Journal: MGI Direct Data Submission
Title: Direct Submission for Tg(tetO-Ppargc1b) 7Dpk
Genotype
Symbol: Tg(tetO-Ppargc1b)7Dpk/?
Background: FVB-Tg(tetO-Ppargc1b)7Dpk
Zygosity: ot
Has Mutant Allele: true
Allele
Name: transgene insertion T37, Bruce M Spiegelman
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Strain
Attribute String: coisogenic, mutant strain, transgenic
Strain
Attribute String: coisogenic, transgenic
Genotype
Symbol: Tg(Ckm-Ppargc1b)T37Brsp/?
Background: FVB-Tg(Ckm-Ppargc1b)T37Brsp
Zygosity: ot
Has Mutant Allele: true
Publication
First Author: Meirhaeghe A
Year: 2003
Journal: Biochem J
Title: Characterization of the human, mouse and rat PGC1 beta (peroxisome-proliferator-activated receptor-gamma co-activator 1 beta) gene in vitro and in vivo.
Volume: 373
Issue: Pt 1
Pages: 155-65
Publication
First Author: Kressler D
Year: 2007
Journal: J Biol Chem
Title: Coactivators PGC-1beta and SRC-1 interact functionally to promote the agonist activity of the selective estrogen receptor modulator tamoxifen.
Volume: 282
Issue: 37
Pages: 26897-907
Publication
First Author: Bourdoncle A
Year: 2005
Journal: J Mol Biol
Title: The nuclear receptor coactivator PGC-1alpha exhibits modes of interaction with the estrogen receptor distinct from those of SRC-1.
Volume: 347
Issue: 5
Pages: 921-34
Publication
First Author: Heery DM
Year: 1997
Journal: Nature
Title: A signature motif in transcriptional co-activators mediates binding to nuclear receptors.
Volume: 387
Issue: 6634
Pages: 733-6
Protein Domain
Type: Domain
Description: This entry represents the RNA recognition motif (RRM) of PPARGC1B (also known as PGC-1beta or PERC), which is one of the members of the PGC-1 transcriptional coactivators family, including PGC-1alpha and PGC-1-related coactivator (PRC). PGC-1beta is a tissue-specifically expressed coactivator of selective nuclear receptors and plays a nonredundant role in controlling mitochondrial oxidative energy metabolism and affects both insulin sensitivity and mitochondrial biogenesis, and functions in a number of oxidative tissues [, , ]. PGC-1beta is a multi-domain protein containing an N-terminal activation domain, an LXXLL coactivator signature [], a tetrapeptide motif (DHDY) responsible for HCF binding, two glutamic/aspartic acid-rich acidic domains, and an RNA recognition motif (RRM). In contrast to PGC-1alpha, PGC-1beta lacks most of the arginine/serine (SR)-rich domain that is responsible for the regulation of RNA processing [].
Publication
First Author: Hallenborg P
Year: 2016
Journal: Am J Physiol Endocrinol Metab
Title: p53 regulates expression of uncoupling protein 1 through binding and repression of PPARγ coactivator-1α.
Volume: 310
Issue: 2
Pages: E116-28
Publication
First Author: Su Z
Year: 2008
Journal: J Lipid Res
Title: Candidate genes for plasma triglyceride, FFA, and glucose revealed from an intercross between inbred mouse strains NZB/B1NJ and NZW/LacJ.
Volume: 49
Issue: 7
Pages: 1500-10
Publication
First Author: Filiano AN
Year: 2013
Journal: PLoS One
Title: Chronic ethanol consumption disrupts the core molecular clock and diurnal rhythms of metabolic genes in the liver without affecting the suprachiasmatic nucleus.
Volume: 8
Issue: 8
Pages: e71684
Protein
Organism: Mus musculus/domesticus
Length: 1014  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1014  
Fragment?: false