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Search results 201 to 222 out of 222 for Ppp1ca

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Type Details Score
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 301
Description: Required for efficient binding to PPP1CA and for targeting PPP1CA to the nucleolus
Type: short sequence motif
End: 304
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Allele
Tg(Ppp1ca-EGFP)HL155Gsat | MGI:4847333
Name: transgene insertion HL155, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Protein Domain
IPR029135 | PPP1R35_C
Type: Domain
Description: This entry represents the C terminus of protein phosphatase 1 regulatory subunit 35. This protein inhibits the serine/threonine-protein phosphatase PPP1CA [].
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Strain
MGI:5003733 | STOCK Tg(Ppp1ca-EGFP)HL155Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Protein
Q9D8C8
Organism: Mus musculus/domesticus
Length: 260  
Fragment?: false
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Protein
F6XYC5
Organism: Mus musculus/domesticus
Length: 144  
Fragment?: true
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Publication
29335436 | J:257713
First Author: Chen M
Year: 2018
Journal: Nat Commun
Title: Deregulated PP1α phosphatase activity towards MAPK activation is antagonized by a tumor suppressive failsafe mechanism.
Volume: 9
Issue: 1
Pages: 159
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Protein Domain
IPR037981 | PPP1CC
Type: Family
Description: Serine/threonine-protein phosphatase PP1 () is a complex of a catalytic subunit, either PPP1CA, PPP1CB or PPP1CC, with one or more regulatory or targeting subunits. Example targeting subunits are PPP1R12A and PPP1R12C, which mediate binding of PP1 to myosin [, , ]; PPP1R3A, which mediates binding to glycogen in the skeletal muscle []; PPP1R7, []; PPP1R15A, which mediates binding to EIF2S1 []. The phosphatase associates with any one of many other regulatory proteins to form a complex that dephosphorylates a specific target protein. For example, centrosome splitting is regulated by the association of NEK2 with PP1 via the PPP1CA subunit [], binding to ATG16L1 antagonizes casein kinase 2-mediated phosphorylation of ATG16L1 affecting the fate of cadiomyocytes []and association with TNF-a induces phosphorylation of FOXP3 which controls regulatory T cell function []. PP1 is required for the cell cycle [], cell division, glycogen metabolism [], muscle contraction []and protein synthesis. PPP1CA and PPP1CB are components of the PTW/PP1 phosphatase complex [].This entry includes the catalytic subunit gamma (PPP1CC) from mammals, Dis2 from fission yeasts and Glc7 from budding yeasts. Glc7 is also a component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB [].
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Publication
21598252 | J:175264
First Author: Molina-Pinelo S
Year: 2011
Journal: J Pathol
Title: Down-regulation of spinophilin in lung tumours contributes to tumourigenesis.
Volume: 225
Issue: 1
Pages: 73-82
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Publication
26334248 | J:229419
 
First Author: Liu R
Year: 2015
Journal: J Mol Cell Cardiol
Title: Cardiac-specific deletion of protein phosphatase 1β promotes increased myofilament protein phosphorylation and contractile alterations.
Volume: 87
Pages: 204-13
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Publication
25001178 | J:213851
First Author: Banzhaf-Strathmann J
Year: 2014
Journal: EMBO J
Title: MicroRNA-125b induces tau hyperphosphorylation and cognitive deficits in Alzheimer's disease.
Volume: 33
Issue: 15
Pages: 1667-80
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Publication
30948508 | J:280519
First Author: Addison WN
Year: 2019
Journal: J Biol Chem
Title: Dephosphorylation of the transcriptional cofactor NACA by the PP1A phosphatase enhances cJUN transcriptional activity and osteoblast differentiation.
Volume: 294
Issue: 20
Pages: 8184-8196
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Publication
19389623 | -
First Author: Hendrickx A
Year: 2009
Journal: Chem Biol
Title: Docking motif-guided mapping of the interactome of protein phosphatase-1.
Volume: 16
Issue: 4
Pages: 365-71
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Protein
P63087
Organism: Mus musculus/domesticus
Length: 323  
Fragment?: false
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Protein
Q3U7K1
Organism: Mus musculus/domesticus
Length: 323  
Fragment?: false
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Protein
A0A0G2JFF1
Organism: Mus musculus/domesticus
Length: 292  
Fragment?: true
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Protein
A0A0G2JGC1
Organism: Mus musculus/domesticus
Length: 273  
Fragment?: false
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Protein
Q6ZWM8
Organism: Mus musculus/domesticus
Length: 323  
Fragment?: false
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Publication
12819204 | -
First Author: Nedea E
Year: 2003
Journal: J Biol Chem
Title: Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends.
Volume: 278
Issue: 35
Pages: 33000-10
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Publication
- | J:100256
     
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data
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