Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:7596097 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-02-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3759328 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:7596098 |
Age: |
postnatal adult |
|
Note: |
Expression is in a group. |
Specimen Label: |
2M |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7596097 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-02-22 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:3777328 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7596098 |
Age: |
postnatal adult |
|
|
Specimen Label: |
2J |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7596097 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-02-22 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3807628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7596098 |
Age: |
postnatal adult |
|
|
Specimen Label: |
2H |
Detected: |
false |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7596097 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-02-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3807528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7596098 |
Age: |
postnatal adult |
|
|
Specimen Label: |
2F |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7596097 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-02-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3807528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7596098 |
Age: |
postnatal adult |
|
|
Specimen Label: |
4 |
Detected: |
true |
Specimen Num: |
17 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7596097 |
Assay Type: |
RNA in situ |
Annotation Date: |
2024-02-22 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3814328 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7596098 |
Age: |
postnatal adult |
|
|
Specimen Label: |
2H |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alappat SR |
Year: |
2003 |
Journal: |
Dev Dyn |
Title: |
Mouse pigpen encodes a nuclear protein whose expression is developmentally regulated during craniofacial morphogenesis. |
Volume: |
228 |
Issue: |
1 |
Pages: |
59-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aubert J |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Screening for mammalian neural genes via fluorescence-activated cell sorter purification of neural precursors from Sox1-gfp knock-in mice. |
Volume: |
100 Suppl 1 |
|
Pages: |
11836-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
1999 |
|
Title: |
Mouse Genome Informatics Orthology Assignments |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Xie W |
Year: |
2009 |
Journal: |
Neurobiol Dis |
Title: |
Tissue and developmental regulation of fragile X mental retardation 1 exon 12 and 15 isoforms. |
Volume: |
35 |
Issue: |
1 |
Pages: |
52-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li MZ |
Year: |
2006 |
Journal: |
Dev Biol |
Title: |
Molecular mapping of developing dorsal horn-enriched genes by microarray and dorsal/ventral subtractive screening. |
Volume: |
292 |
Issue: |
2 |
Pages: |
555-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Centre for Modeling Human Disease |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the NorCOMM project by the Centre for Modeling Human Disease (Cmhd), Institute of Biomaterials & Biomedical Engineering, University of Toronto |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
McKee AE |
Year: |
2005 |
Journal: |
BMC Dev Biol |
Title: |
A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. |
Volume: |
5 |
|
Pages: |
14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP) |
Year: |
2011 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mammalian Functional Genomics Centre |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ingham NJ |
Year: |
2019 |
Journal: |
PLoS Biol |
Title: |
Mouse screen reveals multiple new genes underlying mouse and human hearing loss. |
Volume: |
17 |
Issue: |
4 |
Pages: |
e3000194 |
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators, MGI curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation based on Enzyme Commission mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2016 |
|
Title: |
Automatic assignment of GO terms using logical inference, based on on inter-ontology links |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bedogni F |
Year: |
2021 |
Journal: |
Front Mol Neurosci |
Title: |
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
Volume: |
14 |
|
Pages: |
686034 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
571 |
Description: |
Omega-N-methylarginine; alternate; by PRMT8 |
Type: |
modified residue |
End: |
571 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
595 |
Description: |
Omega-N-methylarginine; alternate; by PRMT8 |
Type: |
modified residue |
End: |
595 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
489 |
Description: |
Asymmetric dimethylarginine; by PRMT8 |
Type: |
modified residue |
End: |
489 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
606 |
Description: |
Omega-N-methylarginine; alternate; by PRMT8 |
Type: |
modified residue |
End: |
606 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
602 |
Description: |
Asymmetric dimethylarginine; by PRMT8 |
Type: |
modified residue |
End: |
602 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
73 |
Description: |
Asymmetric dimethylarginine; by PRMT8 |
Type: |
modified residue |
End: |
73 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
58 |
Description: |
Omega-N-methylarginine; by PRMT8 |
Type: |
modified residue |
End: |
58 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
606 |
Description: |
Asymmetric dimethylarginine; alternate; by PRMT8 |
Type: |
modified residue |
End: |
606 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
595 |
Description: |
Asymmetric dimethylarginine; alternate; by PRMT8 |
Type: |
modified residue |
End: |
595 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
571 |
Description: |
Asymmetric dimethylarginine; alternate; by PRMT8 |
Type: |
modified residue |
End: |
571 |
|
•
•
•
•
•
|
Allele |
Name: |
protein arginine N-methyltransferase 8; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Publication |
First Author: |
Pahlich S |
Year: |
2006 |
Journal: |
Biochim Biophys Acta |
Title: |
Protein arginine methylation: Cellular functions and methods of analysis. |
Volume: |
1764 |
Issue: |
12 |
Pages: |
1890-903 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wolf SS |
Year: |
2009 |
Journal: |
Cell Mol Life Sci |
Title: |
The protein arginine methyltransferase family: an update about function, new perspectives and the physiological role in humans. |
Volume: |
66 |
Issue: |
13 |
Pages: |
2109-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bedford MT |
Year: |
2005 |
Journal: |
Mol Cell |
Title: |
Arginine methylation an emerging regulator of protein function. |
Volume: |
18 |
Issue: |
3 |
Pages: |
263-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bedford MT |
Year: |
2007 |
Journal: |
J Cell Sci |
Title: |
Arginine methylation at a glance. |
Volume: |
120 |
Issue: |
Pt 24 |
Pages: |
4243-6 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Protein arginine methyltransferases (PRMTs) are enzymes that transfer methyl groups to the arginine residues of histones and other proteins. Arginine methylation is an important posttranslational modification process that plays functional roles in transcriptional control, splicing, DNA repair, and signaling [, , ]. PRMTs use S-adenosylmethionine(SAM or AdoMet)-dependent methylation to modify the guanidino nitrogens of the arginine side chain by adding one or two methyl groups []. According to their methylation status, the PRMT enzymes are classified into different group types. While the type-I PRMT enzymes catalyse the formation of monomethylarginine (MMA) and asymmetric dimethylarginine (aDMA), the type-II PRMT enzymes form MMA and symmetric dimethylarginine (sDMA). The enzymes PRMT1, PRMT3, PRMT4, PRMT6 and PRMT8 belong to the type-I and PRMT5, PRMT7 and PRMT9 to type-II. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
394
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
371
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
378
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
354
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
318
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
164
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
343
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
353
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
113
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
350
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
193
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
208
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
113
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
217
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
254
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
298
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
162
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
122
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
235
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
217
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
345
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
254
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
608
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
692
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
651
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
203
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
528
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
637
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
846
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
846
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
418
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
637
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
305
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
448
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
445
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
475
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
231
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
254
 |
Fragment?: |
false |
|
•
•
•
•
•
|