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Search results 201 to 300 out of 1688 for Prnp

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Type Details Score
Publication
15632159 | J:339969
First Author: Fioriti L
Year: 2005
Journal: J Biol Chem
Title: Cytosolic prion protein (PrP) is not toxic in N2a cells and primary neurons expressing pathogenic PrP mutations.
Volume: 280
Issue: 12
Pages: 11320-8
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Publication
26155834 | J:238383
 
First Author: Carulla P
Year: 2015
Journal: Sci Rep
Title: Involvement of PrP(C) in kainate-induced excitotoxicity in several mouse strains.
Volume: 5
Pages: 11971
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Publication
34358614 | J:346542
 
First Author: Lavigna G
Year: 2021
Journal: Neurobiol Dis
Title: Doxycycline rescues recognition memory and circadian motor rhythmicity but does not prevent terminal disease in fatal familial insomnia mice.
Volume: 158
Pages: 105455
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Publication
15542685 | J:94219
First Author: Browning SR
Year: 2004
Journal: J Virol
Title: Transmission of prions from mule deer and elk with chronic wasting disease to transgenic mice expressing cervid PrP.
Volume: 78
Issue: 23
Pages: 13345-50
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Publication
23831375 | J:211720
First Author: Ordóñez-Gutiérrez L
Year: 2013
Journal: Neurobiol Aging
Title: Cellular prion protein modulates β-amyloid deposition in aged APP/PS1 transgenic mice.
Volume: 34
Issue: 12
Pages: 2793-804
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Strain
MGI:5298017 | 129P2/OlaHsd-Prnp<tm2Edin>/H
Attribute String: targeted mutation, mutant strain, coisogenic
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Allele
Prnp<tm2Cwe> | MGI:2682347
Name: prion protein; targeted mutation 2, Charles Weissmann
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Publication
20472884 | J:161315
First Author: Christensen HM
Year: 2010
Journal: Am J Pathol
Title: A highly toxic cellular prion protein induces a novel, nonapoptotic form of neuronal death.
Volume: 176
Issue: 6
Pages: 2695-706
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Publication
25502554 | J:246766
First Author: Sorce S
Year: 2014
Journal: PLoS Pathog
Title: The role of the NADPH oxidase NOX2 in prion pathogenesis.
Volume: 10
Issue: 12
Pages: e1004531
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Publication
25654651 | J:219996
   
First Author: Altmeppen HC
Year: 2015
Journal: Elife
Title: The sheddase ADAM10 is a potent modulator of prion disease.
Volume: 4
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Publication
17569776 | J:142939
First Author: Dong J
Year: 2007
Journal: Am J Pathol
Title: Doppel induces degeneration of cerebellar Purkinje cells independently of Bax.
Volume: 171
Issue: 2
Pages: 599-607
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Publication
27973593 | J:253690
First Author: Donaldson DS
Year: 2016
Journal: PLoS Pathog
Title: Increased Abundance of M Cells in the Gut Epithelium Dramatically Enhances Oral Prion Disease Susceptibility.
Volume: 12
Issue: 12
Pages: e1006075
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Publication
11823413 | J:74652
First Author: Mallucci GR
Year: 2002
Journal: EMBO J
Title: Post-natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration.
Volume: 21
Issue: 3
Pages: 202-10
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Publication
23133383 | J:195363
First Author: Falsig J
Year: 2012
Journal: PLoS Pathog
Title: Prion pathogenesis is faithfully reproduced in cerebellar organotypic slice cultures.
Volume: 8
Issue: 11
Pages: e1002985
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Publication
33137126 | J:297547
First Author: Leca I
Year: 2020
Journal: PLoS Genet
Title: A proteomic survey of microtubule-associated proteins in a R402H TUBA1A mutant mouse.
Volume: 16
Issue: 11
Pages: e1009104
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Publication
20098419 | J:158343
First Author: Bremer J
Year: 2010
Journal: Nat Neurosci
Title: Axonal prion protein is required for peripheral myelin maintenance.
Volume: 13
Issue: 3
Pages: 310-8
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Publication
25510416 | J:225676
 
First Author: Cassard H
Year: 2014
Journal: Nat Commun
Title: Evidence for zoonotic potential of ovine scrapie prions.
Volume: 5
Pages: 5821
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Publication
32673372 | J:346543
First Author: Ghirardini E
Year: 2020
Journal: PLoS Pathog
Title: Mutant prion proteins increase calcium permeability of AMPA receptors, exacerbating excitotoxicity.
Volume: 16
Issue: 7
Pages: e1008654
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Publication
17947689 | J:152995
First Author: Zabel MD
Year: 2007
Journal: J Immunol
Title: Stromal complement receptor CD21/35 facilitates lymphoid prion colonization and pathogenesis.
Volume: 179
Issue: 9
Pages: 6144-52
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Publication
27975168 | J:330089
First Author: Tahir W
Year: 2018
Journal: Mol Neurobiol
Title: Molecular Alterations in the Cerebellum of Sporadic Creutzfeldt-Jakob Disease Subtypes with DJ-1 as a Key Regulator of Oxidative Stress.
Volume: 55
Issue: 1
Pages: 517-537
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Publication
23761404 | J:223991
First Author: Griffiths PC
Year: 2013
Journal: J Gen Virol
Title: Overexpression of chimaeric murine/ovine PrP (A136H154Q171) in transgenic mice facilitates transmission and differentiation of ruminant prions.
Volume: 94
Issue: Pt 11
Pages: 2577-86
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Publication
22163178 | J:183163
First Author: Watts JC
Year: 2011
Journal: PLoS Pathog
Title: Protease-resistant prions selectively decrease Shadoo protein.
Volume: 7
Issue: 11
Pages: e1002382
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Publication
19209230 | J:183308
First Author: Rutishauser D
Year: 2009
Journal: PLoS One
Title: The comprehensive native interactome of a fully functional tagged prion protein.
Volume: 4
Issue: 2
Pages: e4446
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Publication
19100703 | J:142638
First Author: Heikenwalder M
Year: 2008
Journal: Immunity
Title: Lymphotoxin-dependent prion replication in inflammatory stromal cells of granulomas.
Volume: 29
Issue: 6
Pages: 998-1008
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Publication
24965601 | J:339740
First Author: Vergara C
Year: 2015
Journal: Mol Neurobiol
Title: Role of PrP(C) Expression in Tau Protein Levels and Phosphorylation in Alzheimer's Disease Evolution.
Volume: 51
Issue: 3
Pages: 1206-20
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Publication
11792852 | J:73986
First Author: Prinz M
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Lymph nodal prion replication and neuroinvasion in mice devoid of follicular dendritic cells.
Volume: 99
Issue: 2
Pages: 919-24
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Publication
23903654 | J:205018
First Author: Sonati T
Year: 2013
Journal: Nature
Title: The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein.
Volume: 501
Issue: 7465
Pages: 102-6
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Publication
30174115 | J:269374
First Author: Heisler FF
Year: 2018
Journal: Neuron
Title: Muskelin Coordinates PrPC Lysosome versus Exosome Targeting and Impacts Prion Disease Progression.
Volume: 99
Issue: 6
Pages: 1155-1169.e9
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Publication
9414161 | J:44933
First Author: Klein MA
Year: 1997
Journal: Nature
Title: A crucial role for B cells in neuroinvasive scrapie.
Volume: 390
Issue: 6661
Pages: 687-90
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Protein Coding Gene
MGP_CAROLIEiJ_G0024332 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0026534 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0026498 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0026473 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0026510 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0026253 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_97769 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0026955 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0025714 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0026233 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0026367 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0026331 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0026472 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0026351 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0027010 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0025450 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0025788 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0025777 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0025252 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
2890436 | J:8918
First Author: Westaway D
Year: 1987
Journal: Cell
Title: Distinct prion proteins in short and long scrapie incubation period mice.
Volume: 51
Issue: 4
Pages: 651-62
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Publication
3462700 | J:8406
First Author: Locht C
Year: 1986
Journal: Proc Natl Acad Sci U S A
Title: Molecular cloning and complete sequence of prion protein cDNA from mouse brain infected with the scrapie agent.
Volume: 83
Issue: 17
Pages: 6372-6
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Publication
9799790 | J:50880
First Author: Lee IY
Year: 1998
Journal: Genome Res
Title: Complete genomic sequence and analysis of the prion protein gene region from three mammalian species.
Volume: 8
Issue: 10
Pages: 1022-37
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Publication
3923361 | J:7876
First Author: Chesebro B
Year: 1985
Journal: Nature
Title: Identification of scrapie prion protein-specific mRNA in scrapie-infected and uninfected brain.
Volume: 315
Issue: 6017
Pages: 331-3
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Publication
8035877 | J:19448
First Author: Collinge J
Year: 1994
Journal: Nature
Title: Prion protein is necessary for normal synaptic function.
Volume: 370
Issue: 6487
Pages: 295-7
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Publication
8637886 | J:77633
First Author: Lledo PM
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Mice deficient for prion protein exhibit normal neuronal excitability and synaptic transmission in the hippocampus.
Volume: 93
Issue: 6
Pages: 2403-7
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Publication
9837873 | J:163149
First Author: Pauly PC
Year: 1998
Journal: J Biol Chem
Title: Copper stimulates endocytosis of the prion protein.
Volume: 273
Issue: 50
Pages: 33107-10
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Publication
11756421 | J:75094
First Author: Lorenz H
Year: 2002
Journal: J Biol Chem
Title: Cellular phenotyping of secretory and nuclear prion proteins associated with inherited prion diseases.
Volume: 277
Issue: 10
Pages: 8508-16
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Publication
15161660 | J:91094
First Author: Paisley D
Year: 2004
Journal: Am J Pathol
Title: Male infertility and DNA damage in Doppel knockout and prion protein/Doppel double-knockout mice.
Volume: 164
Issue: 6
Pages: 2279-88
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Publication
19381258 | J:240271
First Author: Stevens DJ
Year: 2009
Journal: PLoS Pathog
Title: Early onset prion disease from octarepeat expansion correlates with copper binding properties.
Volume: 5
Issue: 4
Pages: e1000390
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Publication
10842180 | J:64416
First Author: Silverman GL
Year: 2000
Journal: J Biol Chem
Title: Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein. Expression in testis and ectopic production in the brains of Prnp(0/0) mice predisposed to Purkinje cell loss.
Volume: 275
Issue: 35
Pages: 26834-41
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Publication
1373228 | J:472
First Author: Büeler H
Year: 1992
Journal: Nature
Title: Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein.
Volume: 356
Issue: 6370
Pages: 577-82
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Publication
24810941 | J:213227
 
First Author: Hernandez-Rapp J
Year: 2014
Journal: Sci Rep
Title: A PrP(C)-caveolin-Lyn complex negatively controls neuronal GSK3β and serotonin 1B receptor.
Volume: 4
Pages: 4881
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Publication
10987828 | J:126619
First Author: Herms JW
Year: 2000
Journal: J Neurochem
Title: Altered intracellular calcium homeostasis in cerebellar granule cells of prion protein-deficient mice.
Volume: 75
Issue: 4
Pages: 1487-92
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Publication
15951190 | J:104630
First Author: Mayer-Sonnenfeld T
Year: 2005
Journal: Neurobiol Dis
Title: The metabolism of glycosaminoglycans is impaired in prion diseases.
Volume: 20
Issue: 3
Pages: 738-43
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Publication
19664595 | J:152714
First Author: Mays CE
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Enhancement of protein misfolding cyclic amplification by using concentrated cellular prion protein source.
Volume: 388
Issue: 2
Pages: 306-10
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Publication
7912659 | J:18996
First Author: Sailer A
Year: 1994
Journal: Cell
Title: No propagation of prions in mice devoid of PrP.
Volume: 77
Issue: 7
Pages: 967-8
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Publication
26926995 | J:233015
First Author: Nuvolone M
Year: 2016
Journal: J Exp Med
Title: Strictly co-isogenic C57BL/6J-Prnp-/- mice: A rigorous resource for prion science.
Volume: 213
Issue: 3
Pages: 313-27
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Publication
17618696 | J:124113
First Author: Lobão-Soares B
Year: 2007
Journal: Behav Brain Res
Title: Cellular prion protein regulates the motor behaviour performance and anxiety-induced responses in genetically modified mice.
Volume: 183
Issue: 1
Pages: 87-94
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Publication
17056541 | J:140521
First Author: Martínez del Hoyo G
Year: 2006
Journal: J Immunol
Title: Prion protein expression by mouse dendritic cells is restricted to the nonplasmacytoid subsets and correlates with the maturation state.
Volume: 177
Issue: 9
Pages: 6137-42
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Publication
25034251 | J:212238
First Author: Angers R
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Structural effects of PrP polymorphisms on intra- and interspecies prion transmission.
Volume: 111
Issue: 30
Pages: 11169-74
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Publication
16574930 | J:129246
First Author: Weise J
Year: 2006
Journal: Stroke
Title: Deletion of cellular prion protein results in reduced Akt activation, enhanced postischemic caspase-3 activation, and exacerbation of ischemic brain injury.
Volume: 37
Issue: 5
Pages: 1296-300
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Publication
15530652 | J:94449
First Author: Maglio LE
Year: 2004
Journal: Brain Res Mol Brain Res
Title: Hippocampal synaptic plasticity in mice devoid of cellular prion protein.
Volume: 131
Issue: 1-2
Pages: 58-64
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Publication
10818004 | J:62194
First Author: Montrasio F
Year: 2000
Journal: Science
Title: Impaired prion replication in spleens of mice lacking functional follicular dendritic cells.
Volume: 288
Issue: 5469
Pages: 1257-9
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Publication
26608316 | J:230051
First Author: Khalifé M
Year: 2015
Journal: J Virol
Title: Mutated but Not Deleted Ovine PrP(C) N-Terminal Polybasic Region Strongly Interferes with Prion Propagation in Transgenic Mice.
Volume: 90
Issue: 3
Pages: 1638-46
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Publication
16940522 | J:112385
First Author: Tamgüney G
Year: 2006
Journal: J Virol
Title: Transmission of elk and deer prions to transgenic mice.
Volume: 80
Issue: 18
Pages: 9104-14
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Publication
28760925 | J:247312
First Author: West E
Year: 2017
Journal: J Cell Sci
Title: The cholesterol ester cycle regulates signalling complexes and synapse damage caused by amyloid-β.
Volume: 130
Issue: 18
Pages: 3050-3059
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Publication
21277354 | J:170112
 
First Author: Ratté S
Year: 2011
Journal: Neuroscience
Title: Threshold for epileptiform activity is elevated in prion knockout mice.
Volume: 179
Pages: 56-61
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Publication
12758067 | J:126706
First Author: Curtis J
Year: 2003
Journal: Neurobiol Dis
Title: Age-dependent loss of PTP and LTP in the hippocampus of PrP-null mice.
Volume: 13
Issue: 1
Pages: 55-62
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Publication
8845956 | J:128205
First Author: Herms JW
Year: 1995
Journal: Eur J Neurosci
Title: Patch-clamp analysis of synaptic transmission to cerebellar purkinje cells of prion protein knockout mice.
Volume: 7
Issue: 12
Pages: 2508-12
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Publication
32845931 | J:298164
First Author: Chida J
Year: 2020
Journal: PLoS Pathog
Title: Prion protein signaling induces M2 macrophage polarization and protects from lethal influenza infection in mice.
Volume: 16
Issue: 8
Pages: e1008823
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Publication
25202268 | J:288689
 
First Author: Shin HY
Year: 2014
Journal: Front Aging Neurosci
Title: Deficiency of prion protein induces impaired autophagic flux in neurons.
Volume: 6
Pages: 207
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Publication
29220360 | J:254806
First Author: Eigenbrod S
Year: 2017
Journal: PLoS One
Title: Substitutions of PrP N-terminal histidine residues modulate scrapie disease pathogenesis and incubation time in transgenic mice.
Volume: 12
Issue: 12
Pages: e0188989
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Publication
8100741 | J:12900
First Author: Büeler H
Year: 1993
Journal: Cell
Title: Mice devoid of PrP are resistant to scrapie.
Volume: 73
Issue: 7
Pages: 1339-47
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Publication
9582258 | J:47634
First Author: Satoh J
Year: 1998
Journal: Exp Neurol
Title: Cultured skin fibroblasts isolated from mice devoid of the prion protein gene express major heat shock proteins in response to heat stress.
Volume: 151
Issue: 1
Pages: 105-15
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Publication
17098996 | J:136473
First Author: Cordier C
Year: 2006
Journal: J Gen Virol
Title: Transmission and characterization of bovine spongiform encephalopathy sources in two ovine transgenic mouse lines (TgOvPrP4 and TgOvPrP59).
Volume: 87
Issue: Pt 12
Pages: 3763-71
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Publication
20138835 | J:158829
First Author: Lutz J
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Microdeletions within the hydrophobic core region of cellular prion protein alter its topology and metabolism.
Volume: 393
Issue: 3
Pages: 439-44
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Publication
7553876 | J:29186
First Author: Telling GC
Year: 1995
Journal: Cell
Title: Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein.
Volume: 83
Issue: 1
Pages: 79-90
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Publication
26159734 | J:233051
First Author: Richardson DD
Year: 2015
Journal: J Cell Sci
Title: The prion protein inhibits monocytic cell migration by stimulating β1 integrin adhesion and uropod formation.
Volume: 128
Issue: 16
Pages: 3018-29
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Publication
24766164 | J:228555
First Author: Rial D
Year: 2014
Journal: Eur J Neurosci
Title: Cellular prion protein is present in dopaminergic neurons and modulates the dopaminergic system.
Volume: 40
Issue: 3
Pages: 2479-86
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Publication
9030645 | J:38695
First Author: Tobler I
Year: 1997
Journal: J Neurosci
Title: Sleep and sleep regulation in normal and prion protein-deficient mice.
Volume: 17
Issue: 5
Pages: 1869-79
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Publication
18614678 | J:137960
First Author: Prestori F
Year: 2008
Journal: J Neurosci
Title: Altered neuron excitability and synaptic plasticity in the cerebellar granular layer of juvenile prion protein knock-out mice with impaired motor control.
Volume: 28
Issue: 28
Pages: 7091-103
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Publication
17245436 | J:117485
First Author: Baumann F
Year: 2007
Journal: EMBO J
Title: Lethal recessive myelin toxicity of prion protein lacking its central domain.
Volume: 26
Issue: 2
Pages: 538-47
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Publication
21777560 | J:176313
First Author: Seelig DM
Year: 2011
Journal: Am J Pathol
Title: Chronic wasting disease prion trafficking via the autonomic nervous system.
Volume: 179
Issue: 3
Pages: 1319-28
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Publication
26024859 | J:225530
 
First Author: Ramljak S
Year: 2015
Journal: Exp Neurol
Title: Cellular prion protein directly interacts with and enhances lactate dehydrogenase expression under hypoxic conditions.
Volume: 271
Pages: 155-67
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Publication
22948149 | J:192133
First Author: Kang HE
Year: 2012
Journal: J Biol Chem
Title: Characterization of conformation-dependent prion protein epitopes.
Volume: 287
Issue: 44
Pages: 37219-32
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Publication
31726043 | J:283502
 
First Author: Adão-Novaes J
Year: 2020
Journal: Brain Res
Title: Substrain-related dependence of Cu(I)-ATPase activity among prion protein-null mice.
Volume: 1727
Pages: 146550
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Publication
12876477 | J:89766
First Author: Coitinho AS
Year: 2003
Journal: Neuroreport
Title: Cellular prion protein ablation impairs behavior as a function of age.
Volume: 14
Issue: 10
Pages: 1375-9
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Publication
16730679 | J:110404
First Author: Maglio LE
Year: 2006
Journal: Brain Res
Title: Role of cellular prion protein on LTP expression in aged mice.
Volume: 1097
Issue: 1
Pages: 11-8
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Publication
22252492 | J:181928
First Author: Zhang Y
Year: 2011
Journal: Int J Dev Biol
Title: Multiple effects of the cellular prion protein on tooth development.
Volume: 55
Issue: 10-12
Pages: 953-60
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Publication
15082172 | J:89280
First Author: Asante EA
Year: 2004
Journal: Neurosci Lett
Title: Pathogenic human prion protein rescues PrP null phenotype in transgenic mice.
Volume: 360
Issue: 1-2
Pages: 33-6
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Publication
28207746 | J:247923
First Author: Leske H
Year: 2017
Journal: PLoS One
Title: Protease resistance of infectious prions is suppressed by removal of a single atom in the cellular prion protein.
Volume: 12
Issue: 2
Pages: e0170503
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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