|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 201 to 300 out of 4544 for Pten

<< First    < Previous  |  Next >    Last >>
0.409s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
34083580 | J:307288
First Author: Chen J
Year: 2021
Journal: Sci Rep
Title: Transformation of SOX9+ cells by Pten deletion synergizes with steatotic liver injury to drive development of hepatocellular and cholangiocarcinoma.
Volume: 11
Issue: 1
Pages: 11823
•
•
•
•
•
Publication
15944184 | J:100428
First Author: Yue Q
Year: 2005
Journal: Development
Title: PTEN deletion in Bergmann glia leads to premature differentiation and affects laminar organization.
Volume: 132
Issue: 14
Pages: 3281-91
•
•
•
•
•
Publication
21262837 | J:169097
First Author: Tandon P
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Requirement for ribosomal protein S6 kinase 1 to mediate glycolysis and apoptosis resistance induced by Pten deficiency.
Volume: 108
Issue: 6
Pages: 2361-5
•
•
•
•
•
Publication
34638474 | J:328281
 
First Author: Eritja N
Year: 2021
Journal: Cancers (Basel)
Title: Endometrial PTEN Deficiency Leads to SMAD2/3 Nuclear Translocation.
Volume: 13
Issue: 19
•
•
•
•
•
Publication
26180201 | J:225815
First Author: Chen Y
Year: 2015
Journal: J Neurosci
Title: Pten Mutations Alter Brain Growth Trajectory and Allocation of Cell Types through Elevated β-Catenin Signaling.
Volume: 35
Issue: 28
Pages: 10252-67
•
•
•
•
•
Publication
22167068 | J:197590
First Author: Tiozzo C
Year: 2012
Journal: Endocr Relat Cancer
Title: Embryonic epithelial Pten deletion through Nkx2.1-cre leads to thyroid tumorigenesis in a strain-dependent manner.
Volume: 19
Issue: 2
Pages: 111-122
•
•
•
•
•
Publication
27880908 | J:270422
First Author: Yue F
Year: 2016
Journal: Cell Rep
Title: Conditional Loss of Pten in Myogenic Progenitors Leads to Postnatal Skeletal Muscle Hypertrophy but Age-Dependent Exhaustion of Satellite Cells.
Volume: 17
Issue: 9
Pages: 2340-2353
•
•
•
•
•
Publication
23023706 | J:192736
First Author: Tiozzo C
Year: 2012
Journal: J Clin Invest
Title: Mesodermal Pten inactivation leads to alveolar capillary dysplasia- like phenotype.
Volume: 122
Issue: 11
Pages: 3862-72
•
•
•
•
•
Publication
31240311 | J:322113
First Author: Sánchez-Puelles C
Year: 2020
Journal: Cereb Cortex
Title: PTEN Activity Defines an Axis for Plasticity at Cortico-Amygdala Synapses and Influences Social Behavior.
Volume: 30
Issue: 2
Pages: 505-524
•
•
•
•
•
Publication
37558155 | J:339988
 
First Author: Stewart AN
Year: 2023
Journal: Exp Neurol
Title: PTEN knockout using retrogradely transported AAVs transiently restores locomotor abilities in both acute and chronic spinal cord injury.
Volume: 368
Pages: 114502
•
•
•
•
•
Publication
28751459 | J:249247
First Author: Barrows CM
Year: 2017
Journal: J Neurosci
Title: PTEN Loss Increases the Connectivity of Fast Synaptic Motifs and Functional Connectivity in a Developing Hippocampal Network.
Volume: 37
Issue: 36
Pages: 8595-8611
•
•
•
•
•
Publication
19574443 | J:167962
First Author: Tiozzo C
Year: 2009
Journal: Am J Respir Crit Care Med
Title: Deletion of Pten expands lung epithelial progenitor pools and confers resistance to airway injury.
Volume: 180
Issue: 8
Pages: 701-12
•
•
•
•
•
Publication
24893171 | J:218509
First Author: Kim HJ
Year: 2014
Journal: PLoS One
Title: Patterns of gene expression associated with Pten deficiency in the developing inner ear.
Volume: 9
Issue: 6
Pages: e97544
•
•
•
•
•
Publication
22350410 | J:184935
First Author: Mulholland DJ
Year: 2012
Journal: Cancer Res
Title: Pten loss and RAS/MAPK activation cooperate to promote EMT and metastasis initiated from prostate cancer stem/progenitor cells.
Volume: 72
Issue: 7
Pages: 1878-89
•
•
•
•
•
Publication
19587782 | J:151696
First Author: Jagarlamudi K
Year: 2009
Journal: PLoS One
Title: Oocyte-specific deletion of Pten in mice reveals a stage-specific function of PTEN/PI3K signaling in oocytes in controlling follicular activation.
Volume: 4
Issue: 7
Pages: e6186
•
•
•
•
•
Publication
21926349 | J:178784
First Author: Furumoto Y
Year: 2011
Journal: Blood
Title: PTEN deficiency in mast cells causes a mastocytosis-like proliferative disease that heightens allergic responses and vascular permeability.
Volume: 118
Issue: 20
Pages: 5466-75
•
•
•
•
•
Publication
26764354 | J:232645
First Author: Liu YL
Year: 2016
Journal: Blood
Title: Timing of the loss of Pten protein determines disease severity in a mouse model of myeloid malignancy.
Volume: 127
Issue: 15
Pages: 1912-22
•
•
•
•
•
Publication
19435886 | J:207672
First Author: Schade B
Year: 2009
Journal: J Biol Chem
Title: PTEN deficiency in a luminal ErbB-2 mouse model results in dramatic acceleration of mammary tumorigenesis and metastasis.
Volume: 284
Issue: 28
Pages: 19018-26
•
•
•
•
•
Publication
31527903 | J:279960
First Author: Nelson DS
Year: 2019
Journal: PLoS One
Title: BRAF V600E and Pten deletion in mice produces a histiocytic disorder with features of Langerhans cell histiocytosis.
Volume: 14
Issue: 9
Pages: e0222400
•
•
•
•
•
Publication
31377403 | J:353191
 
First Author: LaSarge CL
Year: 2019
Journal: Exp Neurol
Title: Impact of mTOR hyperactive neurons on the morphology and physiology of adjacent neurons: Do PTEN KO cells make bad neighbors?
Volume: 321
Pages: 113029
•
•
•
•
•
Publication
26563471 | J:251220
 
First Author: Hu X
Year: 2015
Journal: Sci Rep
Title: Inhibition of Pten deficient Castration Resistant Prostate Cancer by Targeting of the SET - PP2A Signaling axis.
Volume: 5
Pages: 15182
•
•
•
•
•
Publication
20858757 | J:170203
First Author: Laguë MN
Year: 2010
Journal: Am J Physiol Endocrinol Metab
Title: Decidual PTEN expression is required for trophoblast invasion in the mouse.
Volume: 299
Issue: 6
Pages: E936-46
•
•
•
•
•
Publication
36591296 | J:353485
 
First Author: Zhou X
Year: 2022
Journal: Front Immunol
Title: Microglial Pten safeguards postnatal integrity of the cortex and sociability.
Volume: 13
Pages: 1059364
•
•
•
•
•
Publication
26285813 | J:320862
First Author: Choi JP
Year: 2015
Journal: Endocr Relat Cancer
Title: Androgen actions via androgen receptor promote PTEN inactivation induced uterine cancer.
Volume: 22
Issue: 5
Pages: 687-701
•
•
•
•
•
Publication
19185849 | J:144810
First Author: Guertin DA
Year: 2009
Journal: Cancer Cell
Title: mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice.
Volume: 15
Issue: 2
Pages: 148-59
•
•
•
•
•
Publication
20194734 | J:158751
First Author: Wang H
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Allele-specific tumor spectrum in pten knockin mice.
Volume: 107
Issue: 11
Pages: 5142-7
•
•
•
•
•
Publication
23730527 | J:241985
First Author: Wen Y
Year: 2013
Journal: Aging Dis
Title: Astroglial PTEN Loss Disrupts Neuronal Lamination by Dysregulating Radial Glia-guided Neuronal Migration.
Volume: 4
Issue: 3
Pages: 113-26
•
•
•
•
•
Publication
27849608 | J:239096
First Author: Rangel R
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Transposon mutagenesis identifies genes that cooperate with mutant Pten in breast cancer progression.
Volume: 113
Issue: 48
Pages: E7749-E7758
•
•
•
•
•
Publication
23300485 | J:195087
First Author: Francis JC
Year: 2013
Journal: PLoS Genet
Title: β-catenin is required for prostate development and cooperates with Pten loss to drive invasive carcinoma.
Volume: 9
Issue: 1
Pages: e1003180
•
•
•
•
•
Publication
29337147 | J:261151
 
First Author: Gallent EA
Year: 2018
Journal: Exp Neurol
Title: Neuronal PTEN deletion in adult cortical neurons triggers progressive growth of cell bodies, dendrites, and axons.
Volume: 303
Pages: 12-28
•
•
•
•
•
Publication
31813249 | J:294301
First Author: Shi Y
Year: 2020
Journal: Am J Physiol Renal Physiol
Title: Downregulation of PTEN promotes podocyte endocytosis of lipids aggravating obesity-related glomerulopathy.
Volume: 318
Issue: 3
Pages: F589-F599
•
•
•
•
•
Publication
22940198 | J:299569
First Author: Sanchez-Gurmaches J
Year: 2012
Journal: Cell Metab
Title: PTEN loss in the Myf5 lineage redistributes body fat and reveals subsets of white adipocytes that arise from Myf5 precursors.
Volume: 16
Issue: 3
Pages: 348-62
•
•
•
•
•
Publication
18687666 | J:142150
First Author: Laguë MN
Year: 2008
Journal: Carcinogenesis
Title: Synergistic effects of Pten loss and WNT/CTNNB1 signaling pathway activation in ovarian granulosa cell tumor development and progression.
Volume: 29
Issue: 11
Pages: 2062-72
•
•
•
•
•
Publication
25502566 | J:222654
First Author: Palian BM
Year: 2014
Journal: PLoS Genet
Title: Maf1 is a novel target of PTEN and PI3K signaling that negatively regulates oncogenesis and lipid metabolism.
Volume: 10
Issue: 12
Pages: e1004789
•
•
•
•
•
Publication
23873941 | J:199362
First Author: Wang Q
Year: 2013
Journal: Genes Dev
Title: Spatially distinct roles of class Ia PI3K isoforms in the development and maintenance of PTEN hamartoma tumor syndrome.
Volume: 27
Issue: 14
Pages: 1568-80
•
•
•
•
•
Publication
20400965 | J:166570
First Author: Alimonti A
Year: 2010
Journal: Nat Genet
Title: Subtle variations in Pten dose determine cancer susceptibility.
Volume: 42
Issue: 5
Pages: 454-8
•
•
•
•
•
Publication
30018330 | J:266099
First Author: Sizemore GM
Year: 2018
Journal: Nat Commun
Title: Stromal PTEN determines mammary epithelial response to radiotherapy.
Volume: 9
Issue: 1
Pages: 2783
•
•
•
•
•
Publication
16675393 | J:109635
First Author: Kwon CH
Year: 2006
Journal: Neuron
Title: Pten regulates neuronal arborization and social interaction in mice.
Volume: 50
Issue: 3
Pages: 377-88
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6181556
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6191160
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Pten
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6181556
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191160
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Pten
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6181556
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191160
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Pten
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6181556
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191160
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Pten
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6181556
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191160
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Pten
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6181556
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191160
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Pten
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6181556
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191160
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Pten
Detected: true
Specimen Num: 7
•
•
•
•
•
Publication
27611660 | J:242099
 
First Author: Baohan A
Year: 2016
Journal: Nat Commun
Title: Pten and EphB4 regulate the establishment of perisomatic inhibition in mouse visual cortex.
Volume: 7
Pages: 12829
•
•
•
•
•
Publication
16537919 | J:106937
First Author: Stiles BL
Year: 2006
Journal: Mol Cell Biol
Title: Selective deletion of Pten in pancreatic beta cells leads to increased islet mass and resistance to STZ-induced diabetes.
Volume: 26
Issue: 7
Pages: 2772-81
•
•
•
•
•
Publication
24766807 | J:214411
First Author: Papa A
Year: 2014
Journal: Cell
Title: Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function.
Volume: 157
Issue: 3
Pages: 595-610
•
•
•
•
•
Publication
25512490 | J:216935
First Author: Xu B
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: PTEN signaling through RAF1 proto-oncogene serine/threonine kinase (RAF1)/ERK in the epididymis is essential for male fertility.
Volume: 111
Issue: 52
Pages: 18643-8
•
•
•
•
•
Publication
23817021 | J:200002
First Author: Chen Y
Year: 2013
Journal: Nat Med
Title: ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss.
Volume: 19
Issue: 8
Pages: 1023-9
•
•
•
•
•
Publication
12163417 | J:78415
First Author: Li G
Year: 2002
Journal: Development
Title: Conditional loss of PTEN leads to precocious development and neoplasia in the mammary gland.
Volume: 129
Issue: 17
Pages: 4159-70
•
•
•
•
•
Publication
33534863 | J:301579
First Author: Jones CE
Year: 2021
Journal: PLoS One
Title: Pten regulates collagen fibrillogenesis by fibroblasts through SPARC.
Volume: 16
Issue: 2
Pages: e0245653
•
•
•
•
•
Publication
18474617 | J:137442
First Author: Frew IJ
Year: 2008
Journal: Mol Cell Biol
Title: Combined VHLH and PTEN mutation causes genital tract cystadenoma and squamous metaplasia.
Volume: 28
Issue: 14
Pages: 4536-48
•
•
•
•
•
Publication
25698082 | J:220252
First Author: Joshi A
Year: 2015
Journal: Am J Pathol
Title: Activated mutant p110α causes endometrial carcinoma in the setting of biallelic Pten deletion.
Volume: 185
Issue: 4
Pages: 1104-13
•
•
•
•
•
Publication
22190384 | J:211100
First Author: Antico Arciuch VG
Year: 2011
Journal: Oncotarget
Title: Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors.
Volume: 2
Issue: 12
Pages: 1109-26
•
•
•
•
•
Publication
24497577 | J:210673
First Author: Clipperton-Allen AE
Year: 2014
Journal: Hum Mol Genet
Title: Pten haploinsufficient mice show broad brain overgrowth but selective impairments in autism-relevant behavioral tests.
Volume: 23
Issue: 13
Pages: 3490-505
•
•
•
•
•
Publication
34535684 | J:312395
First Author: Langdon CG
Year: 2021
Journal: Nat Commun
Title: Synthetic essentiality between PTEN and core dependency factor PAX7 dictates rhabdomyosarcoma identity.
Volume: 12
Issue: 1
Pages: 5520
•
•
•
•
•
Publication
19033462 | J:142106
First Author: Fu Y
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium.
Volume: 105
Issue: 49
Pages: 19444-9
•
•
•
•
•
Publication
29461205 | J:263276
   
First Author: González-Fernández E
Year: 2018
Journal: Elife
Title: PTEN negatively regulates the cell lineage progression from NG2+ glial progenitor to oligodendrocyte via mTOR-independent signaling.
Volume: 7
•
•
•
•
•
Publication
24615332 | J:210989
First Author: Melchor L
Year: 2014
Journal: J Pathol
Title: Identification of cellular and genetic drivers of breast cancer heterogeneity in genetically engineered mouse tumour models.
Volume: 233
Issue: 2
Pages: 124-37
•
•
•
•
•
Publication
38901501 | J:359886
 
First Author: Liu Y
Year: 2024
Journal: Free Radic Biol Med
Title: Regulation of YAP translocation by myeloid Pten deficiency alleviates acute lung injury via inhibition of oxidative stress and inflammation.
Volume: 222
Pages: 199-210
•
•
•
•
•
Publication
23393595 | J:197212
First Author: Kim HJ
Year: 2013
Journal: PLoS One
Title: Conditional deletion of pten leads to defects in nerve innervation and neuronal survival in inner ear development.
Volume: 8
Issue: 2
Pages: e55609
•
•
•
•
•
Publication
22836754 | J:191327
First Author: Wang J
Year: 2012
Journal: Cancer Res
Title: B-Raf activation cooperates with PTEN loss to drive c-Myc expression in advanced prostate cancer.
Volume: 72
Issue: 18
Pages: 4765-76
•
•
•
•
•
Publication
29904909 | J:288801
First Author: Sementino E
Year: 2018
Journal: J Cell Physiol
Title: Inactivation of Tp53 and Pten drives rapid development of pleural and peritoneal malignant mesotheliomas.
Volume: 233
Issue: 11
Pages: 8952-8961
•
•
•
•
•
Publication
24794706 | J:210599
First Author: Xu C
Year: 2014
Journal: Cancer Cell
Title: Loss of Lkb1 and Pten leads to lung squamous cell carcinoma with elevated PD-L1 expression.
Volume: 25
Issue: 5
Pages: 590-604
•
•
•
•
•
Publication
26317218 | J:243021
First Author: Filtz EA
Year: 2015
Journal: PLoS One
Title: Rb1 and Pten Co-Deletion in Osteoblast Precursor Cells Causes Rapid Lipoma Formation in Mice.
Volume: 10
Issue: 8
Pages: e0136729
•
•
•
•
•
Publication
22961549 | J:302950
First Author: Zhang Y
Year: 2012
Journal: Brain
Title: PTEN deletion enhances survival, neurite outgrowth and function of dopamine neuron grafts to MitoPark mice.
Volume: 135
Issue: Pt 9
Pages: 2736-49
•
•
•
•
•
Publication
23604118 | J:212371
First Author: Yu M
Year: 2014
Journal: Oncogene
Title: Inactivation of TGF-β signaling and loss of PTEN cooperate to induce colon cancer in vivo.
Volume: 33
Issue: 12
Pages: 1538-47
•
•
•
•
•
Publication
23774212 | J:200612
First Author: Ghosh S
Year: 2013
Journal: Cancer Res
Title: mTOR signaling feedback modulates mammary epithelial differentiation and restrains invasion downstream of PTEN loss.
Volume: 73
Issue: 16
Pages: 5218-31
•
•
•
•
•
Publication
31122699 | J:291195
First Author: Zhang SJ
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Schwann cell-specific PTEN and EGFR dysfunctions affect neuromuscular junction development by impairing Agrin signaling and autophagy.
Volume: 515
Issue: 1
Pages: 50-56
•
•
•
•
•
Publication
31852223 | J:303168
First Author: Lu S
Year: 2020
Journal: Arterioscler Thromb Vasc Biol
Title: PTEN (Phosphatase and Tensin Homolog) Protects Against Ang II (Angiotensin II)-Induced Pathological Vascular Fibrosis and Remodeling-Brief Report.
Volume: 40
Issue: 2
Pages: 394-403
•
•
•
•
•
Publication
29142193 | J:338791
First Author: Wozniak DJ
Year: 2017
Journal: Nat Commun
Title: PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer.
Volume: 8
Issue: 1
Pages: 1508
•
•
•
•
•
Publication
17218262 | J:120364
First Author: Shen WH
Year: 2007
Journal: Cell
Title: Essential role for nuclear PTEN in maintaining chromosomal integrity.
Volume: 128
Issue: 1
Pages: 157-70
•
•
•
•
•
Publication
30165041 | J:270541
First Author: Tu WL
Year: 2018
Journal: Am J Pathol
Title: Pten Haplodeficiency Accelerates Liver Tumor Growth in miR-122a-Null Mice via Expansion of Periportal Hepatocyte-Like Cells.
Volume: 188
Issue: 11
Pages: 2688-2702
•
•
•
•
•
Publication
15951562 | J:114725
First Author: Valiente M
Year: 2005
Journal: J Biol Chem
Title: Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases.
Volume: 280
Issue: 32
Pages: 28936-43
•
•
•
•
•
Publication
21620777 | J:172730
First Author: Mulholland DJ
Year: 2011
Journal: Cancer Cell
Title: Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth.
Volume: 19
Issue: 6
Pages: 792-804
•
•
•
•
•
Publication
33083717 | J:306838
First Author: Kato T
Year: 2020
Journal: iScience
Title: The Loss of Nuclear PTEN Increases Tumorigenesis in a Preclinical Mouse Model for Hepatocellular Carcinoma.
Volume: 23
Issue: 10
Pages: 101548
•
•
•
•
•
Publication
20406970 | J:159457
First Author: Akins EJ
Year: 2010
Journal: Cancer Res
Title: In situ vaccination combined with androgen ablation and regulatory T-cell depletion reduces castration-resistant tumor burden in prostate-specific pten knockout mice.
Volume: 70
Issue: 9
Pages: 3473-82
•
•
•
•
•
Publication
17283127 | J:118219
First Author: Yeager N
Year: 2007
Journal: Cancer Res
Title: Pten loss in the mouse thyroid causes goiter and follicular adenomas: insights into thyroid function and Cowden disease pathogenesis.
Volume: 67
Issue: 3
Pages: 959-66
•
•
•
•
•
Publication
25026288 | J:224513
First Author: Vignarajan S
Year: 2014
Journal: Oncotarget
Title: Loss of PTEN stabilizes the lipid modifying enzyme cytosolic phospholipase A₂α via AKT in prostate cancer cells.
Volume: 5
Issue: 15
Pages: 6289-99
•
•
•
•
•
Publication
32782145 | J:304228
First Author: Li XX
Year: 2020
Journal: Biochem Biophys Res Commun
Title: Schwann cell-specific Pten inactivation reveals essential role of the sympathetic nervous system activity in adipose tissue development.
Volume: 531
Issue: 2
Pages: 118-124
•
•
•
•
•
Publication
27345403 | J:238768
First Author: Su Q
Year: 2017
Journal: Oncogene
Title: Jagged1 upregulation in prostate epithelial cells promotes formation of reactive stroma in the Pten null mouse model for prostate cancer.
Volume: 36
Issue: 5
Pages: 618-627
•
•
•
•
•
Publication
28094257 | J:244565
 
First Author: Yue F
Year: 2017
Journal: Nat Commun
Title: Pten is necessary for the quiescence and maintenance of adult muscle stem cells.
Volume: 8
Pages: 14328
•
•
•
•
•
Publication
24037529 | J:213043
First Author: Macdonald FH
Year: 2014
Journal: Oncogene
Title: PTEN ablation in Ras(Ha)/Fos skin carcinogenesis invokes p53-dependent p21 to delay conversion while p53-independent p21 limits progression via cyclin D1/E2 inhibition.
Volume: 33
Issue: 32
Pages: 4132-43
•
•
•
•
•
Publication
19847259 | J:153747
First Author: Trimboli AJ
Year: 2009
Journal: Nature
Title: Pten in stromal fibroblasts suppresses mammary epithelial tumours.
Volume: 461
Issue: 7267
Pages: 1084-91
•
•
•
•
•
Publication
15657439 | J:95993
First Author: Wijesekara N
Year: 2005
Journal: Mol Cell Biol
Title: Muscle-specific Pten deletion protects against insulin resistance and diabetes.
Volume: 25
Issue: 3
Pages: 1135-45
•
•
•
•
•
Publication
25477498 | J:221383
First Author: Newton RH
Year: 2015
Journal: Blood
Title: Suppression of T-cell lymphomagenesis in mice requires PTEN phosphatase activity.
Volume: 125
Issue: 5
Pages: 852-5
•
•
•
•
•
Publication
26158445 | J:224365
 
First Author: He J
Year: 2015
Journal: Nat Commun
Title: PTEN regulates DNA replication progression and stalled fork recovery.
Volume: 6
Pages: 7620
•
•
•
•
•
Publication
37561626 | J:339664
First Author: Xu Z
Year: 2023
Journal: Cell Rep
Title: PTEN regulates hematopoietic lineage plasticity via PU.1-dependent chromatin accessibility.
Volume: 42
Issue: 8
Pages: 112967
•
•
•
•
•
Publication
23419777 | J:199549
First Author: Jang HD
Year: 2013
Journal: Bone
Title: PTEN regulation by the Akt/GSK-3β axis during RANKL signaling.
Volume: 55
Issue: 1
Pages: 126-31
•
•
•
•
•
Publication
25704959 | J:219855
 
First Author: Danilov CA
Year: 2015
Journal: Exp Neurol
Title: Conditional genetic deletion of PTEN after a spinal cord injury enhances regenerative growth of CST axons and motor function recovery in mice.
Volume: 266
Pages: 147-60
•
•
•
•
•
Publication
23308230 | J:195810
First Author: Kwak MK
Year: 2013
Journal: PLoS One
Title: Conditional deletion of the Pten gene in the mouse prostate induces prostatic intraepithelial neoplasms at early ages but a slow progression to prostate tumors.
Volume: 8
Issue: 1
Pages: e53476
•
•
•
•
•
Publication
16452183 | J:106683
First Author: Yao D
Year: 2006
Journal: Cancer Res
Title: PTEN loss promotes rasHa-mediated papillomatogenesis via dual up-regulation of AKT activity and cell cycle deregulation but malignant conversion proceeds via PTEN-associated pathways.
Volume: 66
Issue: 3
Pages: 1302-12
•
•
•
•
•
Publication
28387983 | J:242917
First Author: Meng Y
Year: 2017
Journal: Dev Dyn
Title: Pten facilitates epiblast epithelial polarization and proamniotic lumen formation in early mouse embryos.
Volume: 246
Issue: 7
Pages: 517-530
•
•
•
•
•
Publication
29273451 | J:273682
First Author: Kopp JL
Year: 2018
Journal: Gastroenterology
Title: Loss of Pten and Activation of Kras Synergistically Induce Formation of Intraductal Papillary Mucinous Neoplasia From Pancreatic Ductal Cells in Mice.
Volume: 154
Issue: 5
Pages: 1509-1523.e5
•
•
•
•
•
Gene
298575 | Pink1
Type: gene
Organism: rat
•
•
•
•
•
Gene
749028 | PINK1
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
510683 | PINK1
Type: gene
Organism: cattle
•
•
•
•
•
Gene
100688445 | PINK1
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
494085 | pink1
Type: gene
Organism: zebrafish
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom