| Type |
Details |
Score |
| Publication |
| First Author: |
The Jackson Laboratory |
| Year: |
2005 |
| Journal: |
Unpublished |
| Title: |
Information obtained from The Jackson Laboratory, Bar Harbor, ME |
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•
•
•
•
•
|
| Publication |
| First Author: |
Tamplin OJ |
| Year: |
2008 |
| Journal: |
BMC Genomics |
| Title: |
Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives. |
| Volume: |
9 |
|
| Pages: |
511 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Araki K |
| Year: |
1999 |
| Journal: |
Cell Mol Biol (Noisy-le-grand) |
| Title: |
Exchangeable gene trap using the Cre/mutated lox system. |
| Volume: |
45 |
| Issue: |
5 |
| Pages: |
737-50 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Taniwaki T |
| Year: |
2005 |
| Journal: |
Dev Growth Differ |
| Title: |
Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. |
| Volume: |
47 |
| Issue: |
3 |
| Pages: |
163-72 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mammalian Functional Genomics Centre |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hansen J |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
| Volume: |
100 |
| Issue: |
17 |
| Pages: |
9918-22 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Friedel RH |
| Year: |
2007 |
| Journal: |
Brief Funct Genomic Proteomic |
| Title: |
EUCOMM--the European conditional mouse mutagenesis program. |
| Volume: |
6 |
| Issue: |
3 |
| Pages: |
180-5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Stryke D |
| Year: |
2003 |
| Journal: |
Nucleic Acids Res |
| Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
| Volume: |
31 |
| Issue: |
1 |
| Pages: |
278-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
GOA curators, MGI curators |
| Year: |
2001 |
|
| Title: |
Gene Ontology annotation based on Enzyme Commission mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GO Central curators, GOA curators, Rhea curators |
| Year: |
2020 |
|
| Title: |
Automatic Gene Ontology annotation based on Rhea mapping |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hansen GM |
| Year: |
2008 |
| Journal: |
Genome Res |
| Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
| Volume: |
18 |
| Issue: |
10 |
| Pages: |
1670-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Helmholtz Zentrum Muenchen GmbH |
| Year: |
2010 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
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|
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•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2014 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Magdaleno S |
| Year: |
2006 |
| Journal: |
PLoS Biol |
| Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
| Volume: |
4 |
| Issue: |
4 |
| Pages: |
e86 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carninci P |
| Year: |
2005 |
| Journal: |
Science |
| Title: |
The transcriptional landscape of the mammalian genome. |
| Volume: |
309 |
| Issue: |
5740 |
| Pages: |
1559-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kawai J |
| Year: |
2001 |
| Journal: |
Nature |
| Title: |
Functional annotation of a full-length mouse cDNA collection. |
| Volume: |
409 |
| Issue: |
6821 |
| Pages: |
685-90 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zambrowicz BP |
| Year: |
2003 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
| Volume: |
100 |
| Issue: |
24 |
| Pages: |
14109-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGD Nomenclature Committee |
| Year: |
1995 |
|
| Title: |
Nomenclature Committee Use |
|
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|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
| Year: |
2008 |
| Journal: |
Database Download |
| Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cyagen Biosciences Inc. |
| Year: |
2022 |
|
| Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
| Year: |
2011 |
|
| Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
UniProt |
| Year: |
2021 |
|
| Title: |
Electronic Gene Ontology annotations created by ARBA machine learning models |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
| Year: |
2004 |
| Journal: |
Database Release |
| Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okazaki Y |
| Year: |
2002 |
| Journal: |
Nature |
| Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
| Volume: |
420 |
| Issue: |
6915 |
| Pages: |
563-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
GemPharmatech |
| Year: |
2020 |
|
| Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
| Year: |
2001 |
|
| Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI Genome Annotation Group and UniGene Staff |
| Year: |
2015 |
| Journal: |
Database Download |
| Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zou D |
| Year: |
2024 |
| Journal: |
Pharmacol Res |
| Title: |
Single-cell and spatial transcriptomics reveals that PTPRG activates the m(6)A methyltransferase VIRMA to block mitophagy-mediated neuronal death in Alzheimer's disease. |
| Volume: |
201 |
|
| Pages: |
107098 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu M |
| Year: |
2016 |
| Journal: |
Oncotarget |
| Title: |
MiR-19b suppresses PTPRG to promote breast tumorigenesis. |
| Volume: |
7 |
| Issue: |
39 |
| Pages: |
64100-64108 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cheung AK |
| Year: |
2015 |
| Journal: |
Oncotarget |
| Title: |
PTPRG suppresses tumor growth and invasion via inhibition of Akt signaling in nasopharyngeal carcinoma. |
| Volume: |
6 |
| Issue: |
15 |
| Pages: |
13434-47 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xiao J |
| Year: |
2014 |
| Journal: |
Int J Cancer |
| Title: |
PTPRG inhibition by DNA methylation and cooperation with RAS gene activation in childhood acute lymphoblastic leukemia. |
| Volume: |
135 |
| Issue: |
5 |
| Pages: |
1101-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mercati O |
| Year: |
2013 |
| Journal: |
Biol Open |
| Title: |
Contactin 4, -5 and -6 differentially regulate neuritogenesis while they display identical PTPRG binding sites. |
| Volume: |
2 |
| Issue: |
3 |
| Pages: |
324-34 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lau LC |
| Year: |
2014 |
| Journal: |
PLoS One |
| Title: |
Association of common variants in TCF4 and PTPRG with Fuchs' corneal dystrophy: a systematic review and meta-analysis. |
| Volume: |
9 |
| Issue: |
10 |
| Pages: |
e109142 |
|
•
•
•
•
•
|
| Allele |
| Name: |
protein tyrosine phosphatase receptor type G; endonuclease-mediated mutation 1, Walter Boron |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Humanized sequence, Inserted expressed sequence, Null/knockout, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
protein tyrosine phosphatase receptor type G; endonuclease-mediated mutation 2, Walter Boron |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Humanized sequence, Inserted expressed sequence, Null/knockout, Reporter |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sheriff S |
| Year: |
2011 |
| Journal: |
J Med Chem |
| Title: |
Small molecule receptor protein tyrosine phosphatase ?? (RPTP??) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop. |
| Volume: |
54 |
| Issue: |
19 |
| Pages: |
6548-62 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Linhares ND |
| Year: |
2014 |
| Journal: |
Genet Mol Res |
| Title: |
Modulation of expressivity in PDGFRB-related infantile myofibromatosis: a role for PTPRG? |
| Volume: |
13 |
| Issue: |
3 |
| Pages: |
6287-92 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
Receptor-type tyrosine-protein phosphatase G (PTPRG), also called protein-tyrosine phosphatase gamma (R-PTP-gamma), belongs to the superfamily of classical tyrosine-specific protein tyrosine phosphatases (PTPs). PTPs () catalyse the dephosphorylation of phosphotyrosine peptides. PTPRG is an important tumour suppressor gene in multiple human cancers such as lung, ovarian, and breast cancers. It is widely expressed in many tissues, including the central nervous system, where it plays a role during neuroinflammation processes. It can dephosphorylate platelet-derived growth factor receptor beta (PDGFRB) and may play a role in PDGFRB-related infantile myofibromatosis. PTPRG is a type 1 integral membrane protein consisting of an extracellular region with a carbonic anhydrase-like (CAH) and a fibronectin type III (FN3) domains, and an intracellular region with a catalytic PTP domain (repeat 1) proximal to the membrane, and a catalytically inactive PTP-fold domain (repeat 2) distal to the membrane. This entry represents the inactive PTP-like domain (repeat 2) [, , , , , , , , , ]. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kuboyama K |
| Year: |
2012 |
| Journal: |
PLoS One |
| Title: |
Protein tyrosine phosphatase receptor type z negatively regulates oligodendrocyte differentiation and myelination. |
| Volume: |
7 |
| Issue: |
11 |
| Pages: |
e48797 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hashemi H |
| Year: |
2011 |
| Journal: |
Mol Cell Neurosci |
| Title: |
Receptor tyrosine phosphatase PTP? is a regulator of spinal cord neurogenesis. |
| Volume: |
46 |
| Issue: |
2 |
| Pages: |
469-82 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
Carbonic anhydrases are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism []. Carbonic anhydrase related proteins (CARPs) are sequence similar to carbonic anhydrases, but they have lost conserved histidines involved in zinc binding and consequently their catalytic activity.This entry represents a carbonic anhydrase-related domain found in tyrosine phosphatase receptors type gamma (Ptprg) [, ]and type zeta (Ptprz), which mediate cell adhesion and signaling during development []. Ptprg is a regulator of spinal cord neurogenesis []. Ptprz negatively regulates oligodendrocyte differentiation and myelination []. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Alonso A |
| Year: |
2016 |
| Journal: |
FEBS J |
| Title: |
The extended human PTPome: a growing tyrosine phosphatase family. |
| Volume: |
283 |
| Issue: |
8 |
| Pages: |
1404-29 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Alonso A |
| Year: |
2016 |
| Journal: |
Methods Mol Biol |
| Title: |
The Extended Family of Protein Tyrosine Phosphatases. |
| Volume: |
1447 |
|
| Pages: |
1-23 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
667
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tripp BC |
| Year: |
2001 |
| Journal: |
J Biol Chem |
| Title: |
Carbonic anhydrase: new insights for an ancient enzyme. |
| Volume: |
276 |
| Issue: |
52 |
| Pages: |
48615-8 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
597
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1612
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
429
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1612
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1442
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1442
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2312
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1463
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1463
 |
| Fragment?: |
false |
|
•
•
•
•
•
|