|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 201 to 300 out of 492 for Pts

<< First    < Previous  |  Next >    Last >>
0.025s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:5309857
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757722
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423183
Age: embryonic day 14.5
Image: EB675; Specimen B402
Specimen Label: EB675; Specimen B402
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691403
Age: postnatal adult
Image: MRC Harwell_1685660
Specimen Label: MRC Harwell_1685660
Detected: true
Specimen Num: 21
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5309857
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757522
Stage: TS22
Assay Id: MGI:5423183
Age: embryonic day 14.5
Specimen Label: EB675; Specimen B402
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3281228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691403
Age: postnatal adult
Image: MRC Harwell_1685658
Specimen Label: MRC Harwell_1685658
Detected: true
Specimen Num: 19
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5309857
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738322
Stage: TS22
Assay Id: MGI:5423183
Age: embryonic day 14.5
Specimen Label: EB675; Specimen B402
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5309857
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5423183
Age: embryonic day 14.5
Specimen Label: EB675; Specimen B402
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691403
Age: postnatal adult
Image: MRC Harwell_1685650
Specimen Label: MRC Harwell_1685650
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691403
Age: postnatal adult
Image: MRC Harwell_1685654
Specimen Label: MRC Harwell_1685654
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691403
Age: postnatal adult
Image: MRC Harwell_1685655
Specimen Label: MRC Harwell_1685655
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691403
Age: postnatal adult
Image: MRC Harwell_1685648
Specimen Label: MRC Harwell_1685648
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5309857
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1768022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423183
Age: embryonic day 14.5
Image: EB675; Specimen B402
Note: Expression was strong in the skull (base and vault).
Specimen Label: EB675; Specimen B402
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5309857
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2672022
Stage: TS22
Assay Id: MGI:5423183
Age: embryonic day 14.5
Note: Expression was not detected in whisker follicle.
Specimen Label: EB675; Specimen B402
Detected: false
Specimen Num: 1
•
•
•
•
•
GO Term
GO:0009401 | phosphoenolpyruvate-dependent sugar phosphotransferase system
•
•
•
•
•
Publication
15556637 | J:94591
First Author: Thöny B
Year: 2004
Journal: FEBS Lett
Title: Tetrahydrobiopterin protects phenylalanine hydroxylase activity in vivo: implications for tetrahydrobiopterin-responsive hyperphenylalaninemia.
Volume: 577
Issue: 3
Pages: 507-11
•
•
•
•
•
Publication
10727395 | J:61559
 
First Author: Thöny B
Year: 2000
Journal: Biochem J
Title: Tetrahydrobiopterin biosynthesis, regeneration and functions.
Volume: 347 Pt 1
Pages: 1-16
•
•
•
•
•
Publication
11591653 | J:103507
First Author: Suzuki H
Year: 2001
Journal: Genome Res
Title: Protein-protein interaction panel using mouse full-length cDNAs.
Volume: 11
Issue: 10
Pages: 1758-65
•
•
•
•
•
Publication
18973680 | J:141291
 
First Author: Tamplin OJ
Year: 2008
Journal: BMC Genomics
Title: Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.
Volume: 9
Pages: 511
•
•
•
•
•
Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
•
•
•
•
•
Publication
18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
•
•
•
•
•
Publication
- | J:342601
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
•
•
•
•
•
Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
•
•
•
•
•
Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
•
•
•
•
•
Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
•
•
•
•
•
Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
•
•
•
•
•
Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
•
•
•
•
•
Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
•
•
•
•
•
Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
•
•
•
•
•
Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
•
•
•
•
•
Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
•
•
•
•
•
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
•
•
•
•
•
Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
•
•
•
•
•
Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
•
•
•
•
•
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
•
•
•
•
•
Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
•
•
•
•
•
Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
•
•
•
•
•
Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
•
•
•
•
•
Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
•
•
•
•
•
Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
•
•
•
•
•
Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Gene
103909285 | mucms2
Type: gene
Organism: zebrafish
•
•
•
•
•
Publication
1911744 | -
First Author: Liao DI
Year: 1991
Journal: Biochemistry
Title: Structure of the IIA domain of the glucose permease of Bacillus subtilis at 2.2-A resolution.
Volume: 30
Issue: 40
Pages: 9583-94
•
•
•
•
•
Protein Domain
IPR002178 | PTS_EIIA_type-2_dom
Type: Domain
Description: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS) [, ]is a major carbohydrate transport system in bacteria. The PTS catalyses the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. The general mechanism of the PTS is the following: a phosphoryl group from phosphoenolpyruvate (PEP) is transferred to enzyme I (EI) of PTS which in turn transfers it to a phosphoryl carrier protein (HPr). Phospho-HPr then transfers the phosphoryl group to a sugar-specific permease which consists of at least three structurally distinct domains (IIA, IIB, and IIC), []which can either be fused together in a single polypeptide chain or exist as two or three interactive chains, formerly called enzymes II (EII) and III (EIII).The first domain (IIA) , carries the first permease-specific phosphorylation site, an histidine which is phosphorylated by phospho-HPr. The second domain (IIB) is phosphorylated by phospho-IIA on a cysteinyl or histidyl residue, depending on the sugar transported. Finally, the phosphoryl group is transferred from the IIB domain to the sugar substrate concomitantly with the sugar uptake processed by the IIC domain. The IIC domain forms the translocation channel and at the specific substrate-binding site. An additional transmembrane domain IID, homologous to IIC, can be found in some PTSs, e.g. for mannose [, , ].According to structural and sequence analyses, the PTS EIIA domain can be divided in five groups [, , ].The PTS EIIA type 1 domain, which is found in the Glucose class of PTS, has an average length of about 100 amino acids. It forms an antiparallel β-barrel structure that incorporates 'Greek key' and 'jellyroll' topological motifs. The phosphorylation site (His) is located in the middle of the domain, at the C terminus of a β-strand [].The PTS EIIA type 2 domain, which is found in the Mannitol class of PTS, has an average length of about 142 amino acids. It consists of an alternating beta/alpha arrangement of five-stranded β-sheet and five α-helices, where the two last alpha helices forms an helical hairpin. The phosphorylation site (His) is located at the N terminus of the domain, at the topological switch-point of the structure, close to the subunit interface [].The PTS EIIA type 3 domain, which is found in the Lactose class of PTS, has an average length of about 100 amino acids. It is composed of three α-helices. The phosphorylation site (His) is located at the C terminus of the domain in the third alpha helix [].The PTS EIIA type 4 domain, which is found in the Mannose class of PTS, has an average length of about 130 amino acids. It consists of a single five-stranded mixed beta sheet, flanked by helices on both sides. The phosphorylation site (His) is located at the end of the third beta strand, in a shallow crevice lined with hydrophobic residues.The PTS EIIA type 5 domain, which is found in the Sorbitol class of PTS, has an average length of about 110 amino acids. The phosphorylation site (His) is located at the N terminus of the domain.EIIA-like domains similar to type 1 to 4 can be found in other kind of proteins, which are mainly transcriptional regulators []. In these cases, the EIIA-like domain is found in association with other domains like the Sigma-54 interaction domain, the DeoR-type HTH domain, or the PTS regulation domain (transcriptional antiterminator). It may possess a regulatory function, through its phosphorylation activity, or act as a simple phosphoryl donor. Some proteins known to contains a EIIA-like domain are listed below:Bacterial transcriptional regulatory proteins levR, nrtC, bglG.Bacterial lactose permease lacS, a non-PTS transport system.Bacterial PTS-dependent dihydroxyacetone kinase, phosphotransferase subunit dhaM.
•
•
•
•
•
Publication
1856179 | -
First Author: Reidl J
Year: 1991
Journal: J Bacteriol
Title: The malX malY operon of Escherichia coli encodes a novel enzyme II of the phosphotransferase system recognizing glucose and maltose and an enzyme abolishing the endogenous induction of the maltose system.
Volume: 173
Issue: 15
Pages: 4862-76
•
•
•
•
•
Protein Domain
IPR011301 | PTS_Mal/Glc-sp_IIBC_component
Type: Family
Description: This entry represents a family of PTS enzyme II fused B and C components including and most closely related to the MalX maltose and glucose-specific transporter of Escherichia coli [].
•
•
•
•
•
Protein Domain
IPR036095 | PTS_EIIB-like_sf
Type: Homologous_superfamily
Description: The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. The lactose/cellobiose-specific family are one of four structurally and functionally distinct group IIB PTS system cytoplasmic enzymes. The fold of IIB cellobiose shows similarstructure to mammalian tyrosine phosphatases. This signature is often found downstream of .The PTS structure presents three layers (alpha/beta/alpha) with parallel β-sheet of four strands.
•
•
•
•
•
Publication
3023349 | -
First Author: Erni B
Year: 1986
Journal: J Biol Chem
Title: Glucose-permease of the bacterial phosphotransferase system. Gene cloning, overproduction, and amino acid sequence of enzyme IIGlc.
Volume: 261
Issue: 35
Pages: 16398-403
•
•
•
•
•
Publication
2120236 | -
First Author: Sutrina SL
Year: 1990
Journal: J Biol Chem
Title: The glucose permease of Bacillus subtilis is a single polypeptide chain that functions to energize the sucrose permease.
Volume: 265
Issue: 30
Pages: 18581-9
•
•
•
•
•
Protein Domain
IPR011299 | PTS_IIBC_glc
Type: Domain
Description: This entry represents the combined B and C domains of the PTS transport system enzyme II specific for glucose transport []. Many of the genes in this family also include an A domain as part of the same polypeptide and thus should be given the name 'PTS system, glucose-specific IIABC component' while the Bacillus subtilus enzyme also contains an enzyme III domain which appears to act independently of the enzyme II domains []. This group is most closely related to the N-acetylglucosamine-specific PTS enzymes ().
•
•
•
•
•
GO Term
GO:0022855 | protein-N(PI)-phosphohistidine-glucose phosphotransferase system transporter activity
•
•
•
•
•
GO Term
GO:0022856 | protein-N(PI)-phosphohistidine-sorbitol phosphotransferase system transporter activity
•
•
•
•
•
GO Term
GO:0022869 | protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
•
•
•
•
•
GO Term
GO:0022870 | protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity
•
•
•
•
•
GO Term
GO:0022871 | protein-N(PI)-phosphohistidine-sorbose phosphotransferase system transporter activity
•
•
•
•
•
GO Term
GO:0022872 | protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity
•
•
•
•
•
GO Term
GO:0022873 | protein-N(PI)-phosphohistidine-maltose phosphotransferase system transporter activity
•
•
•
•
•
GO Term
GO:0022874 | protein-N(PI)-phosphohistidine-cellobiose phosphotransferase system transporter activity
•
•
•
•
•
GO Term
GO:0022875 | protein-N(PI)-phosphohistidine-galactitol phosphotransferase system transmembrane transporter activity
•
•
•
•
•
GO Term
GO:0022876 | protein-N(PI)-phosphohistidine-galactosamine phosphotransferase system transporter activity
•
•
•
•
•
GO Term
GO:0022877 | protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
•
•
•
•
•
GO Term
GO:0022878 | protein-N(PI)-phosphohistidine-sucrose phosphotransferase system transporter activity
•
•
•
•
•
GO Term
GO:0022879 | protein-N(PI)-phosphohistidine-trehalose phosphotransferase system transporter activity
•
•
•
•
•
GO Term
GO:0022880 | protein-N(PI)-phosphohistidine-N-acetylglucosamine phosphotransferase system transporter activity
•
•
•
•
•
GO Term
GO:0022881 | protein-N(PI)-phosphohistidine-N-acetylgalactosamine phosphotransferase system transporter activity
•
•
•
•
•
GO Term
GO:0022882 | protein-N(PI)-phosphohistidine-beta-glucoside phosphotransferase system transporter activity
•
•
•
•
•
Protein Domain
IPR033887 | PTS_IIA_man
Type: Domain
Description: The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation. IIA subunits receive phosphoryl groups from HPr and transfer them to IIB subunits, which in turn phosphorylate the substrate [, ].
•
•
•
•
•
Publication
17158705 | -
First Author: Deutscher J
Year: 2006
Journal: Microbiol Mol Biol Rev
Title: How phosphotransferase system-related protein phosphorylation regulates carbohydrate metabolism in bacteria.
Volume: 70
Issue: 4
Pages: 939-1031
•
•
•
•
•
Publication
9826184 | -
First Author: Kowolik CM
Year: 1998
Journal: Eur J Biochem
Title: The lactose transporter of Staphylococcus aureus--overexpression, purification and characterization of the histidine-tagged domains IIC and IIB.
Volume: 257
Issue: 2
Pages: 389-94
•
•
•
•
•
Protein Domain
IPR041713 | PTS_IIB
Type: Domain
Description: This entry represents the IIB domain found in subunit IIB of enzyme II (EII) of the lactose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS) from Firmicutes as well as Actinobacteria []. In this system, EII is a lactose-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain. The IIC and IIB domains are expressed as a single protein from the lac operon. The IIB domain fold includes a central four-stranded parallel open twisted β-sheet flanked by α-helices on both sides []. The seven major PTS systems with this IIB fold include lactose, chitobiose/lichenan, ascorbate, galactitol, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system [].
•
•
•
•
•
Publication
11447120 | -
First Author: van Tilbeurgh H
Year: 2001
Journal: EMBO J
Title: Crystal structure of an activated form of the PTS regulation domain from the LicT transcriptional antiterminator.
Volume: 20
Issue: 14
Pages: 3789-99
•
•
•
•
•
Publication
2125052 | -
First Author: de Vos WM
Year: 1990
Journal: J Biol Chem
Title: Characterization of the lactose-specific enzymes of the phosphotransferase system in Lactococcus lactis.
Volume: 265
Issue: 36
Pages: 22554-60
•
•
•
•
•
Publication
15667312 | -
First Author: Saier MH
Year: 2005
Journal: Biochem Soc Trans
Title: Evolution of the bacterial phosphotransferase system: from carriers and enzymes to group translocators.
Volume: 33
Issue: Pt 1
Pages: 220-4
•
•
•
•
•
Publication
12949193 | -
First Author: André A
Year: 2003
Journal: Microbiology
Title: Glucose and trehalose PTS permeases of Spiroplasma citri probably share a single IIA domain, enabling the spiroplasma to adapt quickly to carbohydrate changes in its environment.
Volume: 149
Issue: Pt 9
Pages: 2687-96
•
•
•
•
•
Allele
Pts<em1Smoc> | MGI:7291912
Name: 6-pyruvoyl-tetrahydropterin synthase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Publication
9261069 | -
First Author: Sliz P
Year: 1997
Journal: Structure
Title: The structure of enzyme IIAlactose from Lactococcus lactis reveals a new fold and points to possible interactions of a multicomponent system.
Volume: 5
Issue: 6
Pages: 775-88
•
•
•
•
•
Ontology Term
- | Phosphotransferase system
•
•
•
•
•
GO Term
GO:0000268 | peroxisome targeting sequence binding
•
•
•
•
•
GO Term
GO:0103111 | protein-N(pi)-phosphohistidine--N-acetyl-D-glucosamine phosphotransferase activity
•
•
•
•
•
Publication
11532441 | -
First Author: Siebold C
Year: 2001
Journal: FEBS Lett
Title: Carbohydrate transporters of the bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS).
Volume: 504
Issue: 3
Pages: 104-11
•
•
•
•
•
Publication
8676384 | -
First Author: Nunn RS
Year: 1996
Journal: J Mol Biol
Title: Structure of the IIA domain of the mannose transporter from Escherichia coli at 1.7 angstroms resolution.
Volume: 259
Issue: 3
Pages: 502-11
•
•
•
•
•
Strain
MGI:6476122 | C57BL/6JSmoc-Pts<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
•
•
•
•
•
Publication
10393270 | -
First Author: Robillard GT
Year: 1999
Journal: Biochim Biophys Acta
Title: Structure/function studies on the bacterial carbohydrate transporters, enzymes II, of the phosphoenolpyruvate-dependent phosphotransferase system.
Volume: 1422
Issue: 2
Pages: 73-104
•
•
•
•
•
Allele
Tg(DBH-PTS)41Csic | MGI:7513828
Name: transgene insertion 41, Chiho Sumi-Ichinose
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
Publication
7815935 | -
First Author: Saier MH Jr
Year: 1994
Journal: Mol Microbiol
Title: The bacterial phosphotransferase system: new frontiers 30 years later.
Volume: 13
Issue: 5
Pages: 755-64
•
•
•
•
•
Publication
11361063 | -
First Author: Tchieu JH
Year: 2001
Journal: J Mol Microbiol Biotechnol
Title: The complete phosphotransferase system in Escherichia coli.
Volume: 3
Issue: 3
Pages: 329-46
•
•
•
•
•
DO Term
DOID:0090106 | BH4-deficient hyperphenylalaninemia A
•
•
•
•
•
Publication
1537788 | -
First Author: Saier MH Jr
Year: 1992
Journal: J Bacteriol
Title: Proposed uniform nomenclature for the proteins and protein domains of the bacterial phosphoenolpyruvate: sugar phosphotransferase system.
Volume: 174
Issue: 5
Pages: 1433-8
•
•
•
•
•
Publication
8246840 | -
First Author: Postma PW
Year: 1993
Journal: Microbiol Rev
Title: Phosphoenolpyruvate:carbohydrate phosphotransferase systems of bacteria.
Volume: 57
Issue: 3
Pages: 543-94
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom